LOCUS       NM_001100890            2724 bp    mRNA    linear   ROD 09-OCT-2023
DEFINITION  Rattus norvegicus G-rich RNA sequence binding factor 1 (Grsf1),
            mRNA.
ACCESSION   NM_001100890 XM_001073361 XM_223327
VERSION     NM_001100890.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Wang J, Lu J, Zhu Y, Huang Q, Gu Q, Tian S, Ge J, Lin X and Sha W.
  TITLE     Guanine-rich RNA sequence binding factor 1 regulates neuronal
            ferroptosis after spinal cord injury in rats via the GPX4 signaling
            pathway
  JOURNAL   Brain Res 1818, 148497 (2023)
   PUBMED   37506966
  REMARK    GeneRIF: Guanine-rich RNA sequence binding factor 1 regulates
            neuronal ferroptosis after spinal cord injury in rats via the GPX4
            signaling pathway.
REFERENCE   2  (bases 1 to 2724)
  AUTHORS   Pietras Z, Wojcik MA, Borowski LS, Szewczyk M, Kulinski TM,
            Cysewski D, Stepien PP, Dziembowski A and Szczesny RJ.
  TITLE     Dedicated surveillance mechanism controls G-quadruplex forming
            non-coding RNAs in human mitochondria
  JOURNAL   Nat Commun 9 (1), 2558 (2018)
   PUBMED   29967381
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2724)
  AUTHORS   Antonicka H and Shoubridge EA.
  TITLE     Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA
            Processing and Ribosome Biogenesis
  JOURNAL   Cell Rep 10 (6), 920-932 (2015)
   PUBMED   25683715
REFERENCE   4  (bases 1 to 2724)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 2724)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 2724)
  AUTHORS   Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J.
  TITLE     Dissecting Wnt/beta-catenin signaling during gastrulation using RNA
            interference in mouse embryos
  JOURNAL   Development 132 (11), 2599-2609 (2005)
   PUBMED   15857914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK474968.1, FM050032.1, CK601425.1 and BC103654.1.
            
            On or before Dec 20, 2009 this sequence version replaced
            XM_223327.4, XM_001073361.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                CK474968.1         1-39
            40-586              FM050032.1         1-547
            587-1029            CK601425.1         3-445
            1030-2724           BC103654.1         1-1695
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..2724
                     /gene="Grsf1"
                     /note="G-rich RNA sequence binding factor 1"
                     /db_xref="GeneID:305256"
                     /db_xref="RGD:1310858"
     exon            1..372
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..1458
                     /gene="Grsf1"
                     /codon_start=1
                     /product="G-rich sequence factor 1"
                     /protein_id="NP_001094360.1"
                     /db_xref="GeneID:305256"
                     /db_xref="RGD:1310858"
                     /translation="MAGTRWVLGALLRGCGCNCSSCRRTGAACLPFYSAAGTFPSGVS
                     GRRRLLLLLGAAAAAASQTRGLQLGPAAAGRLAGPVPVRPSAAAAAAASYSALRAPLL
                     PRSLAAAAGPARGYCQESKTTYLEDLPPLPEYELSPSKLGEEVDDVYLIRAQGLPWSC
                     TVEDVLSFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQ
                     RYVEVYEINNEDVDALMKSLQVKPTPALSDGVVRLRGLPYSCNEKDIVDFFAGLNIVD
                     ITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNEVRTHVGS
                     HKGKKMVSSPTTKYITEPEVVFEEHEVNEDARPMTAFESEKEIELPKEMSDKLAEAVD
                     FGAVPSLHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFDTHE
                     DAVAAMLKDRSHVQHRYIELFLNSCPKGK"
     exon            373..529
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            530..685
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            686..829
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..965
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1150
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1272
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1408
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1484
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..2696
                     /gene="Grsf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgccgcctc cggagcccat ggccgggacg cgctgggtgc taggggcgtt gctccggggc
       61 tgcggctgca actgcagcag ctgccggcga accggtgccg cctgcctgcc cttctactcg
      121 gccgccggca ctttcccgtc cggcgtctct ggccgccgcc gcctgctgct actcctcggg
      181 gccgccgcgg ccgccgcttc gcagacgcgg ggcctgcagc tcgggcctgc ggccgccggg
      241 agactggcgg gtcccgtccc tgtccggccc tccgccgccg cggcggctgc cgcgtcctac
      301 tcggcgttgc gcgccccgct gcttccgcga tcgctggccg ccgccgcggg cccggcgcgg
      361 ggttactgcc aggagtccaa aactacctac ctggaagacc tcccaccact acctgagtac
      421 gaactgagcc catccaagtt aggagaagag gtggatgatg tttacctcat tcgagctcag
      481 ggtctgccct ggtcctgcac tgtggaagat gtcctcagct ttttctcaga ctgcagaatc
      541 cgaaacagtg agaatggaat acatttcctc ctgaacagag atggcaaacg gaggggcgat
      601 gccttgattg aaatggagtc cgagcaggat gtacagaagg ccttggaaaa gcaccggatg
      661 tacatggggc agcggtatgt ggaagtgtat gaaataaaca acgaagatgt ggatgcctta
      721 atgaagagcc tacaggtcaa gcctacgcct gcactcagtg acggtgtggt ccgcctgaga
      781 ggactccctt acagctgcaa tgaaaaggac attgtggact tctttgcagg actgaacata
      841 gtagacatca cttttgtgat ggactataga gggagaagaa aaacagggga agcctatgta
      901 cagtttgaag aaccagaaat ggccaaccaa gcgcttctga agcacaggga agagattggt
      961 aaccgataca tagagatatt tccaagcaga aggaatgaag ttcgcacaca cgttggatct
     1021 cataaaggaa agaaaatggt gtcttctcct actaccaaat atataactga accagaagtg
     1081 gtgtttgagg aacatgaagt taatgaggac gctcggccca tgacagcttt tgaaagtgaa
     1141 aaagagatag agttgcctaa ggagatgtca gacaaacttg cagaggctgt tgactttgga
     1201 gctgtgccgt ccctgcattt tgtccacatg agaggattgc ctttccaagc caatgcccag
     1261 gacatcataa atttctttgc cccactgaag cctgtgagaa tcaccatgga gtacagctcc
     1321 agcggaaagg ccactggaga agctgacgtg cactttgata cccatgagga tgctgttgct
     1381 gccatgctca aggaccggtc gcatgtccaa cataggtata ttgagctgtt cctaaattca
     1441 tgtcctaaag gaaaataaga cttgaacaga ccccagaaga taaggatgga gcaggaagca
     1501 cctcgtttgc acatctctgg cataaaaaga tgagttgatt ggcagtggct gctggagaaa
     1561 ggatctgtgc gtctcagtgc tgtgtctaca ccgagaaaga tgcggctggg actctgaaat
     1621 aagcctcaca tgtacatttt cgtctaagca gtggttgaga aagtcgggcc tgtgtgttga
     1681 gttttctgac acagaggcca tattacagac gtgagatgat ctttccaccc agtgctgctc
     1741 ctcagatcct tactcctggt tgttgcctct gactgagggc tctgatacaa agctcatgga
     1801 ataaattaat ggtgtatttt taccaagcac tcaccaaagc agcaggaggt tcagaacttt
     1861 actaagccag tctgattggg tcaaacagtt ttgctttttt tcattttgat tttcatttga
     1921 ttacttaggg atagaacttt taaaaaatag caaaccacag attagtgagt gtaagtgacc
     1981 actcggcagt tttgtcttta gaaacacttt gcctccttaa gcctttgacc tgaaagcatt
     2041 tgacgttggt gcctgtctgt gtcttggaaa cctagacttc acttccttca cgtttttttg
     2101 gacaaatctt aaggctatta ggtttgaaat cgtaatgtga catatcaaag cagtccagac
     2161 tggtaaggac attaatcgct tcacttgaat taaaccagct ctagataagg gggaaacaat
     2221 cttaagtctc ctcctctgct tttccagtgg ggtagccatc ccatatttta gaacaagtag
     2281 gggtgccttg cttaaataaa actagcattt catgtataat tgtgtgaagg ttctatggct
     2341 agagctgtat ttctgtcaca ttgtggcagc accttctgct ttaatactaa atagcttgtt
     2401 atttaaatat tggataaaat ggctggcttc aaaaatagtc attaataaac ttaactttat
     2461 gtatacctgt gtagaagaat caaagtcctg tatattttct ttgccttgtt cctattctca
     2521 gggtgacagc tgccaccaag agataataag tctcactctt cagattgaat tttctgagct
     2581 ttcagaggtg gtaacctgga agaaacgtgt attgcttagt tcataaccac ctgggattac
     2641 cagctaaggg gcaaaattac tgtcctgtag acaataaatg aaggtttcaa gtcgaaaaaa
     2701 aaaaaaaaaa aaaaaaaaaa aaaa
//
