LOCUS       NM_001109513            2028 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus GrpE-like 2, mitochondrial (Grpel2), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001109513 XM_001065348
VERSION     NM_001109513.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2028)
  AUTHORS   Schulz C, Schendzielorz A and Rehling P.
  TITLE     Unlocking the presequence import pathway
  JOURNAL   Trends Cell Biol 25 (5), 265-275 (2015)
   PUBMED   25542066
  REMARK    Review article
REFERENCE   2  (bases 1 to 2028)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   3  (bases 1 to 2028)
  AUTHORS   Da Cruz S, Xenarios I, Langridge J, Vilbois F, Parone PA and
            Martinou JC.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   4  (bases 1 to 2028)
  AUTHORS   Naylor DJ, Stines AP, Hoogenraad NJ and Hoj PB.
  TITLE     Evidence for the existence of distinct mammalian cytosolic,
            microsomal, and two mitochondrial GrpE-like proteins, the
            Co-chaperones of specific Hsp70 members
  JOURNAL   J Biol Chem 273 (33), 21169-21177 (1998)
   PUBMED   9694873
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473971.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001065348.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV764723.1, DY575570.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2028
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..2028
                     /gene="Grpel2"
                     /gene_synonym="Afap1l1"
                     /note="GrpE-like 2, mitochondrial"
                     /db_xref="GeneID:688777"
                     /db_xref="RGD:1585231"
     exon            1..97
                     /gene="Grpel2"
                     /gene_synonym="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..698
                     /gene="Grpel2"
                     /gene_synonym="Afap1l1"
                     /note="AFAP1-like protein 1; actin filament-associated
                     protein 1-like 1"
                     /codon_start=1
                     /product="grpE protein homolog 2, mitochondrial"
                     /protein_id="NP_001102983.1"
                     /db_xref="GeneID:688777"
                     /db_xref="RGD:1585231"
                     /translation="MAARSLWAVQRLQRLLASGAVSESRGWLHPFSTATQRTAGEDCS
                     SEDPPDGLGPSLAEQALRLKAVKLEKEVQDLTLRYQRAVADCENIRRRTQRCVEDAKI
                     FGIQSFCKDLVEVADILEKTAECFSDGAEPQDHKLTLEKVFQGLSLLEAKLKSVFTKH
                     GLEKMAPIGDKYDPHEHELICHMPAGVGVQPGTVALVRQDGYKLHGRTIRLAQVEVAV
                     ESQRRL"
     exon            98..251
                     /gene="Grpel2"
                     /gene_synonym="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            252..333
                     /gene="Grpel2"
                     /gene_synonym="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            334..2028
                     /gene="Grpel2"
                     /gene_synonym="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgtcggcgc tctaatctgg aacatggcgg cgcgttcgct gtgggcggtg cagcgtctgc
       61 agcgcctact ggcctccggg gctgtgtcag agagcagggg atggctacac cctttcagca
      121 ctgccaccca gagaactgct ggggaagact gcagttctga ggaccctcct gatggacttg
      181 gtccctccct tgctgaacag gccttaaggc taaaagctgt taaactggaa aaagaagtcc
      241 aggatttaac actgagatac cagagagccg tcgctgactg tgaaaacata aggagacgga
      301 cccagagatg tgtggaagat gcgaagatat ttgggatcca gagcttctgt aaggacctcg
      361 tggaggtagc agacattttg gagaagactg ccgagtgctt ttcagacgga gctgaacctc
      421 aggaccacaa gcttactctg gaaaaagtct tccaagggct gtccctgtta gaagcaaagc
      481 tgaaaagtgt gtttaccaag catggcctag agaaaatggc acccatcggt gacaaatacg
      541 accctcatga gcatgaactc atctgccaca tgccagcagg tgttggggtg cagcctggca
      601 ccgtggcatt agttcggcag gatggctaca aacttcatgg ccgcaccatt agacttgcac
      661 aagtggaagt ggcagtagag tctcaaagaa ggctctgaac aggtgactgg aaccaaaccc
      721 tgtcctagag tcaggcacct gtctccttta tttattaagc tggtttgtat tatacatgag
      781 gtccttcgtg tgctccacct cggatttagt cacattggct gtgtctctgc agtgtcttat
      841 gggcttatgt gacctgtttg gtcttatcag gagtcctgcc actaggcatt tgaacaatgt
      901 gacgagtgcc atgtggcctt tatcaaaatg tttacagaaa tcatttaaat tggtactcag
      961 atgactgaat ccagaacctt cttacctgtg ttttcatctg actgctggaa ctagtgcagc
     1021 atctgtatct tgagtttttg ggaaagggaa atggtgggga ttggttttga catttaggta
     1081 cgtggatgaa taatgcctta cccttgtata aatttagatc atttgggctg gagtggagag
     1141 agacttccca aggccccttt tttattgcgc atttcattca gtcatctctt gtgcttgtat
     1201 tcccttctag ggtcacactc acactgtttc atagccaccc ctttccggtc ccttttggaa
     1261 gggctaaagg gtcaggccag tcttcctttt ttgttgttgg taaggtgaat acgtttatca
     1321 ttaaactagt ctcaagtcta agaacaggca agccctggtt gccttgacaa cacaacccaa
     1381 tcccagaaac caaaagcctc catacatctc aagtcggaga aatagacttt agggaccagg
     1441 catgatggct atcaattcaa aaataaaaac agaatgctaa ggtggataat ttcttacagt
     1501 atataattta cacagacgtg atgctgcttg cctcccttgc atggactcgg aagggccatc
     1561 ctcctttctg gattagggtg tggggctgct ttggaaagaa cagggaactt cctatagcag
     1621 cagcaacaaa aataaatata aaatgaatgt gtccacattg tgaaacactt gctgtcacct
     1681 tcaccattcc agtttttaaa tcctgagtcc aaagcaccaa gaaaaatttt ttgcatattt
     1741 ataattgacg aaaagatcaa agttgtctca gttctgcata tgttttgtta agaaaaggtg
     1801 tgacacagct cctagaactc cacctagaat cattgcaaag gaagggccgt attccccgag
     1861 tccttcttgg tgcactgtat ctgctggaag gtaaggcaga ggtgcaggat gccgggggaa
     1921 ttagtgtatc ctgtagtcat cagtgcctga gtacatggtg gtaccaccag agggcactgt
     1981 cggcactgag gcctttgcgg acattgacat cacacttaat gatggaag
//
