LOCUS       XM_017588777            6886 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus glutamate metabotropic receptor 1
            (Grm1), transcript variant X1, mRNA.
ACCESSION   XM_017588777
VERSION     XM_017588777.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017588777.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017588777.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6886
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6886
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /note="glutamate metabotropic receptor 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 8 ESTs, 19 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     19 samples with support for all annotated introns"
                     /db_xref="GeneID:24414"
                     /db_xref="RGD:2742"
     CDS             442..4041
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /codon_start=1
                     /product="metabotropic glutamate receptor 1 isoform X1"
                     /protein_id="XP_017444266.1"
                     /db_xref="GeneID:24414"
                     /db_xref="RGD:2742"
                     /translation="MVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGD
                     VIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLG
                     SEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVI
                     GPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDI
                     VKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRK
                     LRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEA
                     NGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKK
                     VCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGRKL
                     LDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNID
                     DYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCRACD
                     LGWWPNAELTGCEPIPVRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVK
                     SSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRI
                     ARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIK
                     EVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIW
                     LAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVV
                     RMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQAPKGQHVWQRLS
                     VHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEEDNTPSAHFSPPS
                     SPSMVVHRRGPPVATTPPLPPHLTAEETPLFLADSVIPKGLPPPLPQQQPQQPPPQQP
                     PQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNSLRSLYPPPPPPQHLQMLPLH
                     LSTFQEESISPPGEDDDDDSERFKLLQEFVYEREGNTEEDELEEEEDLPTASKLTPED
                     SPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL"
ORIGIN      
        1 gtcctctgac ctgagaccaa tagctgtgtc tacccggact caggtaggtc ttggagtaca
       61 tactccaaac tggctcaggt gagcggatat cttcctgagg tgaaagccac ccctcaaatg
      121 aagcgtccag ctcaccgcca ctaacgcgcc gcgcattgga cacctgatcc acacaccttc
      181 gggcaccagt gaaaaaccgc gacttgattt tctggaagaa cgcccccagg gtgtgggagc
      241 ggtcgtggag gaccagcagg aggaagcgga ggggagaggg gcagtagtgg aggcagagaa
      301 agcgttgaac cagctgtgtt ggccgaaggc acgaaaaggc aaaaggcagc ggtgagcatc
      361 tgtgtggttc ccgctgggaa cctgcaggca ggaccggcgt gggaacgtgg ctggcccgcg
      421 gtggaccgcg tcttcgccac aatggtccgg ctcctcttga ttttcttccc aatgatcttt
      481 ttggagatgt ccattttgcc caggatgcct gacagaaaag tattgctggc aggtgcctcg
      541 tcccagcgct ccgtggcgag aatggacgga gatgtcatca tcggagccct cttctcagtc
      601 catcaccagc ctccagccga gaaggtaccc gaaaggaagt gtggggagat cagggaacag
      661 tatggtatcc agagggtgga ggccatgttc cacacgttgg ataagattaa cgcggacccg
      721 gtgctcctgc ccaacatcac tctgggcagt gagatccggg actcctgctg gcactcttca
      781 gtggctctcg aacagagcat cgaattcatc agagactccc tgatttccat ccgagatgag
      841 aaggatgggc tgaaccgatg cctgcctgat ggccagaccc tgccccctgg caggactaag
      901 aagcctattg ctggagtgat cggccctggc tccagctctg tggccattca agtccagaat
      961 cttctccagc tgttcgacat cccacagatc gcctattctg ccacaagcat agacctgagt
     1021 gacaaaactt tgtacaaata cttcctgagg gtggtccctt ctgacacttt gcaggcaagg
     1081 gcgatgctcg acatagtcaa gcgttacaac tggacctatg tctcagcagt ccacacagaa
     1141 gggaattacg gcgagagtgg aatggatgct ttcaaagaac tggctgccca ggaaggcctc
     1201 tgcatcgcac actcggacaa aatctacagc aatgctggcg agaagagctt tgaccggctc
     1261 ctgcgtaaac tccgggagcg gcttcccaag gccagggttg tggtctgctt ctgcgagggc
     1321 atgacagtgc ggggcttact gagtgccatg cgccgcctgg gcgtcgtggg cgagttctca
     1381 ctcattggaa gtgatggatg ggcagacaga gatgaagtca tcgaaggcta tgaggtggaa
     1441 gccaacggag ggatcacaat aaagcttcag tctccagagg tcaggtcatt tgatgactac
     1501 ttcctgaagc tgaggctgga caccaacaca aggaatcctt ggttccctga gttctggcaa
     1561 catcgcttcc agtgtcgcct acctggacac ctcttggaaa accccaactt taagaaagtg
     1621 tgcacaggaa atgaaagctt ggaagaaaac tatgtccagg acagcaaaat gggatttgtc
     1681 atcaatgcca tctatgccat ggcacatggg ctgcagaaca tgcaccatgc tctgtgtccc
     1741 ggccatgtgg gcctgtgtga tgctatgaaa cccattgatg gcaggaagct cctggatttc
     1801 ctcatcaaat cctcttttgt cggagtgtct ggagaggagg tgtggttcga tgagaagggg
     1861 gatgctcccg gaaggtatga cattatgaat ctgcagtaca cagaagctaa tcgctatgac
     1921 tatgtccacg tggggacctg gcatgaagga gtgctgaata ttgatgatta caaaatccaa
     1981 atgaacaaaa gcggaatggt acgatctgtg tgcagtgagc cttgcttaaa gggtcagatt
     2041 aaggtcatac ggaaaggaga agtgagctgc tgctggatct gcacggcctg caaagagaat
     2101 gagtttgtgc aggacgagtt cacctgcaga gcctgtgacc tggggtggtg gcccaacgca
     2161 gagctcacag gctgtgagcc cattcctgtc cgttatcttg agtggagtga catagaatct
     2221 atcatagcca tcgccttttc ttgcctgggc atcctcgtga cgctgtttgt caccctcatc
     2281 ttcgttctgt accgggacac acccgtggtc aaatcctcca gtagggagct ctgctatatc
     2341 attctggctg gtattttcct cggctatgtg tgccctttca ccctcatcgc caaacctact
     2401 accacatcct gctacctcca gcgcctccta gttggcctct cttctgccat gtgctactct
     2461 gctttagtga ccaaaaccaa tcgtattgca cgcatcctgg ctggcagcaa gaagaagatc
     2521 tgcacccgga agcccagatt catgagcgct tgggcccaag tgatcatagc ctccattctg
     2581 attagtgtac agctaacact agtggtgacc ttgatcatca tggagcctcc catgcccatt
     2641 ttgtcctacc cgagtatcaa ggaagtctac cttatctgca ataccagcaa cctgggtgta
     2701 gtggcccctg tgggttacaa tggactcctc atcatgagct gtacctacta tgccttcaag
     2761 acccgcaacg tgccggccaa cttcaatgag gctaaataca tcgccttcac catgtacact
     2821 acctgcatca tctggctggc tttcgttccc atttactttg ggagcaacta caagatcatc
     2881 actacctgct tcgcggtgag cctcagtgtg acggtggccc tggggtgcat gtttactccg
     2941 aagatgtaca tcatcattgc caaacctgag aggaacgtcc gcagtgcctt cacgacctct
     3001 gatgttgtcc gcatgcacgt cggtgatggc aaactgccgt gccgctccaa caccttcctc
     3061 aacattttcc ggagaaagaa gcccggggca gggaatgcca attctaacgg caagtctgtg
     3121 tcatggtctg aaccaggtgg aagacaggcg cccaagggac agcacgtgtg gcagcgcctc
     3181 tctgtgcacg tgaagaccaa cgagacggcc tgtaaccaaa cagccgtaat caaacccctc
     3241 actaaaagtt accaaggctc tggcaagagc ctgacctttt cagatgccag caccaagacc
     3301 ctttacaatg tggaagaaga ggacaatacc ccttctgctc acttcagccc tcccagcagc
     3361 ccttctatgg tggtgcaccg acgcgggcca cccgtggcca ccacaccacc tctgccaccc
     3421 catctgaccg cagaagagac ccccctgttc ctggctgatt ccgtcatccc caagggcttg
     3481 cctcctcctc tcccgcagca gcagccacag cagccgcccc ctcagcagcc cccgcagcag
     3541 cccaagtccc tgatggacca gctgcaaggc gtagtcacca acttcggttc ggggattcca
     3601 gatttccatg cggtgctggc aggcccgggg acaccaggaa acagcctgcg ctctctgtac
     3661 ccgcccccgc ctccgccgca acacctgcag atgctgcccc tgcacctgag caccttccag
     3721 gaggagtcca tctcccctcc tggggaggac gacgatgatg acagtgagag attcaagctc
     3781 ctgcaggagt tcgtgtacga gcgcgaaggg aacaccgaag aagatgaatt ggaagaggag
     3841 gaggacctgc ccacagccag caagctgacc cctgaggatt ctcctgccct gacgcctcct
     3901 tctcctttcc gagattccgt ggcctctggc agctcagtgc ccagttcccc cgtatctgag
     3961 tcggtcctct gcacccctcc aaatgtgacc tacgcctctg tcattctgag ggactacaag
     4021 caaagctctt ccaccctgta gtgtgtgtgt gtgtgggggg ggagtgcgca tggagaagcc
     4081 agagatgcca aggagtgtca acccttccag aaatgtgtag aaagcagggt gagggatggg
     4141 gatggaggac cacggtctgc agggaagaaa aaaaaaatgc tgcggctgcc ttaaagaagg
     4201 agagggacga tgccaactga acagtggtcc tggccaggat tgtgactctt gaattattca
     4261 aaaaccttct ctagaaagaa agggaattat gacaaagcac aattccatat ggtatgtaac
     4321 ttttatcgaa aaaaataata aaacgtaaaa ataaaatcaa caaaaataat ctcttctttt
     4381 gctcaatcgt gcatacatat atctgcccac actcccgtgg taaaactaga agcgaagcag
     4441 gccctgcgat ggtgccaact gaatcctaag ttcatcatcc tagtgagcag atggagagag
     4501 ggcaggaggc gggggtaggt tcggacaaca gctcccatct cagaccttga ctgtgctgag
     4561 tcttcagact cctggactaa ggaagacccg gggactgacc ttatgagggt ccctttccac
     4621 tgctgtgatc cattgccagc ctgtagtcac ccgggataaa ggcacagtaa ccttttgcat
     4681 tcctgtgatt ccctgtgttt aaggaaaagg aaagtatgag caaagctatc accaaaaaga
     4741 gcgccattag aagttacggg ggagaaaaaa agaaaagcaa gatgatatat aagcacaggg
     4801 ccttgaacaa ggtgagcgtg cttcacagat tccgtattaa tgtacagata cttttggaga
     4861 ggagaaagat aacaaggagt gtcaggccgt ttgtgaactc acttgcactg tgccaaccag
     4921 gttctccgct gcccttcagc aaaagaggac aagccgcgtt gccaggtttt accttccatt
     4981 tactgtagca aatactatca accagtcgga cttctaagat tcagtttcag tttcagtaca
     5041 atgcggtgcc actgtttctc ccatgtgcta tggaaacgaa tctatctttg aacttaatga
     5101 tgtattcata gcaactatta ctggtttaga ttttttcctt ttgtcacagg agtccctgga
     5161 actagtaact gaaagtgttt tcctgcgttt cttgtataca tgtgattatg aaattcgtgc
     5221 catttaatgt caatttagct gtcactagaa gactgtcttt tggatatagt ataaatattt
     5281 ttatgtacca gtgatgttct ccataccacg gttaccatgt ttctctggag gttgggtctg
     5341 tggtctgatg tttctcatgt gcagcttcga tgggaattct tctaagtggg atttattttt
     5401 cagatatttt atgatatgag aatgttatta atgaagtaat ttgaaagtgc attgtataaa
     5461 aatggtcacc aagcaatgcg tgacagtaaa aggtccgttt ttataaacct gcgcacattg
     5521 ttattaaaat gtaaggttga aaaggcaata tttagaatat ttcagatata tttttaaaaa
     5581 gtttttccac agctacttga gtttcatggt cttctagtat ataacaacac tcaagtctac
     5641 ccagagtgtc tcaactatct gcttgtcaat tctgcttaat tttattttca tgcatttaaa
     5701 cttttatatc tttgttagca tctcttcctt atgatcctca tgtgtactat tatgtaataa
     5761 ccacatacat gtaatatcca catacatgta atatccacac atgtaacatt cacatacatg
     5821 tagtccagtt attccatctt gaccctacct tttcgaaccc aaaagaaaat tgttcttgtt
     5881 atttttattt cttctgttat ttgtgagatg aacccgttcc ctttaaataa tctttgtttg
     5941 tgccttatgt tcagtcattt taatttgctg tcttcatgtc gaagctgctg gtttctcagc
     6001 caaaaagcat catcttagac tctctaaata gccaaagcat catgagtttg gaatttaaca
     6061 tcagctccca tgtcagagtt gtgctcctca tgtgatccca cattctactg cccagtgtag
     6121 tgaattcctt tccaagaact cttgcctttg ctttccaagt tatttttgag catcttggtt
     6181 gcagagatct caagaattta cgtcttggat tccacgtttt cactacgaag aaacagaatg
     6241 agaagaagaa gaaaaattag gcagtgtaga gctgggcgta gtggtccagg tctttaagcc
     6301 caggctagcc tgatttagcc aataaattct aggcctaaaa agagagacct gtctcaaaac
     6361 tcaaagcaca caacagatgc taagtagatg ggtctccata attgggaagc caatgagaga
     6421 atgcatattt cttcctatgt tctttaaaac ttgaagcagt tacatccgtc tttcatcatt
     6481 acgggactcg tgcgttcaga gccttttgtt gttcttttgc cagaatagat gaggcaacat
     6541 ttgcctattc gaatgctgta acaggcaagt tgactctagg gttttggtct gagacatttg
     6601 gtgaacacct tcaacactga ttaaaatatt actgaatgcc tactcttatc ctgattatga
     6661 atcttccaga ataaatagaa tattagctca tataattgtt cagaattgga gatgtatgcc
     6721 tactaccctg tacctaaagg gcaaaaatat cttcactgta atgtgtgtgc ttcttcaagg
     6781 tgttttgctt cttgtaaaag tgttttcctt tggcttgtta ctgccttttg tcagataatc
     6841 ttgatgacgc tgtatcataa taaatatttt ctatttatta aatggg
//
