LOCUS       NM_017011               6814 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus glutamate metabotropic receptor 1 (Grm1),
            transcript variant 1, mRNA.
ACCESSION   NM_017011
VERSION     NM_017011.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6814)
  AUTHORS   Liu,D., Wang,J., Tian,E., Chen,J., Kong,W., Lu,Y. and Zhang,S.
  TITLE     mGluR1/IP3/ERK signaling pathway regulates vestibular compensation
            in ON UBCs of the cerebellar flocculus
  JOURNAL   CNS Neurosci Ther 30 (2), e14419 (2024)
   PUBMED   37622292
  REMARK    GeneRIF: mGluR1/IP3/ERK signaling pathway regulates vestibular
            compensation in ON UBCs of the cerebellar flocculus.
REFERENCE   2  (bases 1 to 6814)
  AUTHORS   Taketo,M.
  TITLE     Activation of adenosine A1 receptor potentiates metabotropic
            glutamate receptor 1-mediated Ca2+ mobilization in the rat
            hippocampal marginal zone
  JOURNAL   Brain Res 1821, 148581 (2023)
   PUBMED   37714421
  REMARK    GeneRIF: Activation of adenosine A1 receptor potentiates
            metabotropic glutamate receptor 1-mediated Ca[2+] mobilization in
            the rat hippocampal marginal zone.
REFERENCE   3  (bases 1 to 6814)
  AUTHORS   Li,C.H., Zhao,C.L. and Liu,Y.Z.
  TITLE     [Activation of metabotropic glutamate receptor 1 inhibits chronic
            intermittent hypoxia-induced carotid body plasticity in rats]
  JOURNAL   Sheng Li Xue Bao 75 (5), 629-635 (2023)
   PUBMED   37909134
  REMARK    GeneRIF: [Activation of metabotropic glutamate receptor 1 inhibits
            chronic intermittent hypoxia-induced carotid body plasticity in
            rats].
REFERENCE   4  (bases 1 to 6814)
  AUTHORS   Bai,T., Chen,H., Hu,W., Liu,J., Lin,X., Chen,S., Luo,F., Yang,X.,
            Chen,J. and Li,C.
  TITLE     Amygdala Metabotropic Glutamate Receptor 1 Influences Synaptic
            Transmission to Participate in Fentanyl-Induced Hyperalgesia in
            Rats
  JOURNAL   Cell Mol Neurobiol 43 (3), 1401-1412 (2023)
   PUBMED   35798932
  REMARK    GeneRIF: Amygdala Metabotropic Glutamate Receptor 1 Influences
            Synaptic Transmission to Participate in Fentanyl-Induced
            Hyperalgesia in Rats.
REFERENCE   5  (bases 1 to 6814)
  AUTHORS   Speranza,L., Inglebert,Y., De Sanctis,C., Wu,P.Y., Kalinowska,M.,
            McKinney,R.A. and Francesconi,A.
  TITLE     Stabilization of Spine Synaptopodin by mGluR1 Is Required for
            mGluR-LTD
  JOURNAL   J Neurosci 42 (9), 1666-1678 (2022)
   PUBMED   35046120
  REMARK    GeneRIF: Stabilization of Spine Synaptopodin by mGluR1 Is Required
            for mGluR-LTD.
REFERENCE   6  (bases 1 to 6814)
  AUTHORS   Baude,A., Nusser,Z., Roberts,J.D., Mulvihill,E., McIlhinney,R.A.
            and Somogyi,P.
  TITLE     The metabotropic glutamate receptor (mGluR1 alpha) is concentrated
            at perisynaptic membrane of neuronal subpopulations as detected by
            immunogold reaction
  JOURNAL   Neuron 11 (4), 771-787 (1993)
   PUBMED   8104433
REFERENCE   7  (bases 1 to 6814)
  AUTHORS   Pin,J.P., Waeber,C., Prezeau,L., Bockaert,J. and Heinemann,S.F.
  TITLE     Alternative splicing generates metabotropic glutamate receptors
            inducing different patterns of calcium release in Xenopus oocytes
  JOURNAL   Proc Natl Acad Sci U S A 89 (21), 10331-10335 (1992)
   PUBMED   1438218
REFERENCE   8  (bases 1 to 6814)
  AUTHORS   Tanabe,Y., Masu,M., Ishii,T., Shigemoto,R. and Nakanishi,S.
  TITLE     A family of metabotropic glutamate receptors
  JOURNAL   Neuron 8 (1), 169-179 (1992)
   PUBMED   1309649
REFERENCE   9  (bases 1 to 6814)
  AUTHORS   Houamed,K.M., Kuijper,J.L., Gilbert,T.L., Haldeman,B.A.,
            O'Hara,P.J., Mulvihill,E.R., Almers,W. and Hagen,F.S.
  TITLE     Cloning, expression, and gene structure of a G protein-coupled
            glutamate receptor from rat brain
  JOURNAL   Science 252 (5010), 1318-1321 (1991)
   PUBMED   1656524
REFERENCE   10 (bases 1 to 6814)
  AUTHORS   Masu,M., Tanabe,Y., Tsuchida,K., Shigemoto,R. and Nakanishi,S.
  TITLE     Sequence and expression of a metabotropic glutamate receptor
  JOURNAL   Nature 349 (6312), 760-765 (1991)
   PUBMED   1847995
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 26, 2020 this sequence version replaced NM_017011.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (alpha).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M61099.1, X57569.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                JAXUCZ010000001.1  7273386-7273443     c
            59-1076             JAXUCZ010000001.1  7271023-7272040     c
            1077-1326           JAXUCZ010000001.1  7142053-7142302     c
            1327-1562           JAXUCZ010000001.1  6977303-6977538     c
            1563-1809           JAXUCZ010000001.1  6940914-6941160     c
            1810-1978           JAXUCZ010000001.1  6935514-6935682     c
            1979-2105           JAXUCZ010000001.1  6927212-6927338     c
            2106-3036           JAXUCZ010000001.1  6911256-6912186     c
            3037-6814           JAXUCZ010000001.1  6878545-6882322     c
FEATURES             Location/Qualifiers
     source          1..6814
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     gene            1..6814
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /note="glutamate metabotropic receptor 1"
                     /db_xref="GeneID:24414"
                     /db_xref="RGD:2742"
     exon            1..58
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            59..1076
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             377..3976
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /note="isoform alpha precursor is encoded by transcript
                     variant 1; metabotropic glutamate receptor 1; mGluR1; G
                     protein coupled receptor family C group 1 member A;
                     glutamate receptor, metabotropic 1"
                     /codon_start=1
                     /product="metabotropic glutamate receptor 1 isoform alpha
                     precursor"
                     /protein_id="NP_058707.2"
                     /db_xref="GeneID:24414"
                     /db_xref="RGD:2742"
                     /translation="MVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGD
                     VIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLG
                     SEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVI
                     GPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDI
                     VKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRK
                     LRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEA
                     NGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKK
                     VCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGRKL
                     LDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNID
                     DYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCRACD
                     LGWWPNAELTGCEPIPVRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVK
                     SSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRI
                     ARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIK
                     EVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIW
                     LAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVV
                     RMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQAPKGQHVWQRLS
                     VHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEEDNTPSAHFSPPS
                     SPSMVVHRRGPPVATTPPLPPHLTAEETPLFLADSVIPKGLPPPLPQQQPQQPPPQQP
                     PQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNSLRSLYPPPPPPQHLQMLPLH
                     LSTFQEESISPPGEDDDDDSERFKLLQEFVYEREGNTEEDELEEEEDLPTASKLTPED
                     SPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL"
     exon            1077..1326
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1562
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1809
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1978
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1979..2105
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2106..3036
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..6814
                     /gene="Grm1"
                     /gene_synonym="Gprc1a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagaacgg ctgcagtcct ctgacctgag accaatagct gtgtctaccc ggactcagcg
       61 tccagctcac cgccactaac gcgccgcgca ttggacacct gatccacaca ccttcgggca
      121 ccagtgaaaa accgcgactt gattttctgg aagaacgccc ccagggtgtg ggagcggtcg
      181 tggaggacca gcaggaggaa gcggagggga gaggggcagt agtggaggca gagaaagcgt
      241 tgaaccagct gtgttggccg aaggcacgaa aaggcaaaag gcagcggtga gcatctgtgt
      301 ggttcccgct gggaacctgc aggcaggacc ggcgtgggaa cgtggctggc ccgcggtgga
      361 ccgcgtcttc gccacaatgg tccggctcct cttgattttc ttcccaatga tctttttgga
      421 gatgtccatt ttgcccagga tgcctgacag aaaagtattg ctggcaggtg cctcgtccca
      481 gcgctccgtg gcgagaatgg acggagatgt catcatcgga gccctcttct cagtccatca
      541 ccagcctcca gccgagaagg tacccgaaag gaagtgtggg gagatcaggg aacagtatgg
      601 tatccagagg gtggaggcca tgttccacac gttggataag attaacgcgg acccggtgct
      661 cctgcccaac atcactctgg gcagtgagat ccgggactcc tgctggcact cttcagtggc
      721 tctcgaacag agcatcgaat tcatcagaga ctccctgatt tccatccgag atgagaagga
      781 tgggctgaac cgatgcctgc ctgatggcca gaccctgccc cctggcagga ctaagaagcc
      841 tattgctgga gtgatcggcc ctggctccag ctctgtggcc attcaagtcc agaatcttct
      901 ccagctgttc gacatcccac agatcgccta ttctgccaca agcatagacc tgagtgacaa
      961 aactttgtac aaatacttcc tgagggtggt cccttctgac actttgcagg caagggcgat
     1021 gctcgacata gtcaagcgtt acaactggac ctatgtctca gcagtccaca cagaagggaa
     1081 ttacggcgag agtggaatgg atgctttcaa agaactggct gcccaggaag gcctctgcat
     1141 cgcacactcg gacaaaatct acagcaatgc tggcgagaag agctttgacc ggctcctgcg
     1201 taaactccgg gagcggcttc ccaaggccag ggttgtggtc tgcttctgcg agggcatgac
     1261 agtgcggggc ttactgagtg ccatgcgccg cctgggcgtc gtgggcgagt tctcactcat
     1321 tggaagtgat ggatgggcag acagagatga agtcatcgaa ggctatgagg tggaagccaa
     1381 cggagggatc acaataaagc ttcagtctcc agaggtcagg tcatttgatg actacttcct
     1441 gaagctgagg ctggacacca acacaaggaa tccttggttc cctgagttct ggcaacatcg
     1501 cttccagtgt cgcctacctg gacacctctt ggaaaacccc aactttaaga aagtgtgcac
     1561 aggaaatgaa agcttggaag aaaactatgt ccaggacagc aaaatgggat ttgtcatcaa
     1621 tgccatctat gccatggcac atgggctgca gaacatgcac catgctctgt gtcccggcca
     1681 tgtgggcctg tgtgatgcta tgaaacccat tgatggcagg aagctcctgg atttcctcat
     1741 caaatcctct tttgtcggag tgtctggaga ggaggtgtgg ttcgatgaga agggggatgc
     1801 tcccggaagg tatgacatta tgaatctgca gtacacagaa gctaatcgct atgactatgt
     1861 ccacgtgggg acctggcatg aaggagtgct gaatattgat gattacaaaa tccaaatgaa
     1921 caaaagcgga atggtacgat ctgtgtgcag tgagccttgc ttaaagggtc agattaaggt
     1981 catacggaaa ggagaagtga gctgctgctg gatctgcacg gcctgcaaag agaatgagtt
     2041 tgtgcaggac gagttcacct gcagagcctg tgacctgggg tggtggccca acgcagagct
     2101 cacaggctgt gagcccattc ctgtccgtta tcttgagtgg agtgacatag aatctatcat
     2161 agccatcgcc ttttcttgcc tgggcatcct cgtgacgctg tttgtcaccc tcatcttcgt
     2221 tctgtaccgg gacacacccg tggtcaaatc ctccagtagg gagctctgct atatcattct
     2281 ggctggtatt ttcctcggct atgtgtgccc tttcaccctc atcgccaaac ctactaccac
     2341 atcctgctac ctccagcgcc tcctagttgg cctctcttct gccatgtgct actctgcttt
     2401 agtgaccaaa accaatcgta ttgcacgcat cctggctggc agcaagaaga agatctgcac
     2461 ccggaagccc agattcatga gcgcttgggc ccaagtgatc atagcctcca ttctgattag
     2521 tgtacagcta acactagtgg tgaccttgat catcatggag cctcccatgc ccattttgtc
     2581 ctacccgagt atcaaggaag tctaccttat ctgcaatacc agcaacctgg gtgtagtggc
     2641 ccctgtgggt tacaatggac tcctcatcat gagctgtacc tactatgcct tcaagacccg
     2701 caacgtgccg gccaacttca atgaggctaa atacatcgcc ttcaccatgt acactacctg
     2761 catcatctgg ctggctttcg ttcccattta ctttgggagc aactacaaga tcatcactac
     2821 ctgcttcgcg gtgagcctca gtgtgacggt ggccctgggg tgcatgttta ctccgaagat
     2881 gtacatcatc attgccaaac ctgagaggaa cgtccgcagt gccttcacga cctctgatgt
     2941 tgtccgcatg cacgtcggtg atggcaaact gccgtgccgc tccaacacct tcctcaacat
     3001 tttccggaga aagaagcccg gggcagggaa tgccaattct aacggcaagt ctgtgtcatg
     3061 gtctgaacca ggtggaagac aggcgcccaa gggacagcac gtgtggcagc gcctctctgt
     3121 gcacgtgaag accaacgaga cggcctgtaa ccaaacagcc gtaatcaaac ccctcactaa
     3181 aagttaccaa ggctctggca agagcctgac cttttcagat gccagcacca agacccttta
     3241 caatgtggaa gaagaggaca ataccccttc tgctcacttc agccctccca gcagcccttc
     3301 tatggtggtg caccgacgcg ggccacccgt ggccaccaca ccacctctgc caccccatct
     3361 gaccgcagaa gagacccccc tgttcctggc tgattccgtc atccccaagg gcttgcctcc
     3421 tcctctcccg cagcagcagc cacagcagcc gccccctcag cagcccccgc agcagcccaa
     3481 gtccctgatg gaccagctgc aaggcgtagt caccaacttc ggttcgggga ttccagattt
     3541 ccatgcggtg ctggcaggcc cggggacacc aggaaacagc ctgcgctctc tgtacccgcc
     3601 cccgcctccg ccgcaacacc tgcagatgct gcccctgcac ctgagcacct tccaggagga
     3661 gtccatctcc cctcctgggg aggacgacga tgatgacagt gagagattca agctcctgca
     3721 ggagttcgtg tacgagcgcg aagggaacac cgaagaagat gaattggaag aggaggagga
     3781 cctgcccaca gccagcaagc tgacccctga ggattctcct gccctgacgc ctccttctcc
     3841 tttccgagat tccgtggcct ctggcagctc agtgcccagt tcccccgtat ctgagtcggt
     3901 cctctgcacc cctccaaatg tgacctacgc ctctgtcatt ctgagggact acaagcaaag
     3961 ctcttccacc ctgtagtgtg tgtgtgtgtg gggggggagt gcgcatggag aagccagaga
     4021 tgccaaggag tgtcaaccct tccagaaatg tgtagaaagc agggtgaggg atggggatgg
     4081 aggaccacgg tctgcaggga agaaaaaaaa aatgctgcgg ctgccttaaa gaaggagagg
     4141 gacgatgcca actgaacagt ggtcctggcc aggattgtga ctcttgaatt attcaaaaac
     4201 cttctctaga aagaaaggga attatgacaa agcacaattc catatggtat gtaactttta
     4261 tcgaaaaaaa taataaaacg taaaaataaa atcaacaaaa ataatctctt cttttgctca
     4321 atcgtgcata catatatctg cccacactcc cgtggtaaaa ctagaagcga agcaggccct
     4381 gcgatggtgc caactgaatc ctaagttcat catcctagtg agcagatgga gagagggcag
     4441 gaggcggggg taggttcgga caacagctcc catctcagac cttgactgtg ctgagtcttc
     4501 agactcctgg actaaggaag acccggggac tgaccttatg agggtccctt tccactgctg
     4561 tgatccattg ccagcctgta gtcacccggg ataaaggcac agtaaccttt tgcattcctg
     4621 tgattccctg tgtttaagga aaaggaaagt atgagcaaag ctatcaccaa aaagagcgcc
     4681 attagaagtt acgggggaga aaaaaagaaa agcaagatga tatataagca cagggccttg
     4741 aacaaggtga gcgtgcttca cagattccgt attaatgtac agatactttt ggagaggaga
     4801 aagataacaa ggagtgtcag gccgtttgtg aactcacttg cactgtgcca accaggttct
     4861 ccgctgccct tcagcaaaag aggacaagcc gcgttgccag gttttacctt ccatttactg
     4921 tagcaaatac tatcaaccag tcggacttct aagattcagt ttcagtttca gtacaatgcg
     4981 gtgccactgt ttctcccatg tgctatggaa acgaatctat ctttgaactt aatgatgtat
     5041 tcatagcaac tattactggt ttagattttt tccttttgtc acaggagtcc ctggaactag
     5101 taactgaaag tgttttcctg cgtttcttgt atacatgtga ttatgaaatt cgtgccattt
     5161 aatgtcaatt tagctgtcac tagaagactg tcttttggat atagtataaa tatttttatg
     5221 taccagtgat gttctccata ccacggttac catgtttctc tggaggttgg gtctgtggtc
     5281 tgatgtttct catgtgcagc ttcgatggga attcttctaa gtgggattta tttttcagat
     5341 attttatgat atgagaatgt tattaatgaa gtaatttgaa agtgcattgt ataaaaatgg
     5401 tcaccaagca atgcgtgaca gtaaaaggtc cgtttttata aacctgcgca cattgttatt
     5461 aaaatgtaag gttgaaaagg caatatttag aatatttcag atatattttt aaaaagtttt
     5521 tccacagcta cttgagtttc atggtcttct agtatataac aacactcaag tctacccaga
     5581 gtgtctcaac tatctgcttg tcaattctgc ttaattttat tttcatgcat ttaaactttt
     5641 atatctttgt tagcatctct tccttatgat cctcatgtgt actattatgt aataaccaca
     5701 tacatgtaat atccacatac atgtaatatc cacacatgta acattcacat acatgtagtc
     5761 cagttattcc atcttgaccc taccttttcg aacccaaaag aaaattgttc ttgttatttt
     5821 tatttcttct gttatttgtg agatgaaccc gttcccttta aataatcttt gtttgtgcct
     5881 tatgttcagt cattttaatt tgctgtcttc atgtcgaagc tgctggtttc tcagccaaaa
     5941 agcatcatct tagactctct aaatagccaa agcatcatga gtttggaatt taacatcagc
     6001 tcccatgtca gagttgtgct cctcatgtga tcccacattc tactgcccag tgtagtgaat
     6061 tcctttccaa gaactcttgc ctttgctttc caagttattt ttgagcatct tggttgcaga
     6121 gatctcaaga atttacgtct tggattccac gttttcacta cgaagaaaca gaatgagaag
     6181 aagaagaaaa attaggcagt gtagagctgg gcgtagtggt ccaggtcttt aagcccaggc
     6241 tagcctgatt tagccaataa attctaggcc taaaaagaga gacctgtctc aaaactcaaa
     6301 gcacacaaca gatgctaagt agatgggtct ccataattgg gaagccaatg agagaatgca
     6361 tatttcttcc tatgttcttt aaaacttgaa gcagttacat ccgtctttca tcattacggg
     6421 actcgtgcgt tcagagcctt ttgttgttct tttgccagaa tagatgaggc aacatttgcc
     6481 tattcgaatg ctgtaacagg caagttgact ctagggtttt ggtctgagac atttggtgaa
     6541 caccttcaac actgattaaa atattactga atgcctactc ttatcctgat tatgaatctt
     6601 ccagaataaa tagaatatta gctcatataa ttgttcagaa ttggagatgt atgcctacta
     6661 ccctgtacct aaagggcaaa aatatcttca ctgtaatgtg tgtgcttctt caaggtgttt
     6721 tgcttcttgt aaaagtgttt tcctttggct tgttactgcc ttttgtcaga taatcttgat
     6781 gacgctgtat cataataaat attttctatt tatt
//
