LOCUS       NM_017261               6745 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Rattus norvegicus glutamate ionotropic receptor AMPA type subunit 2
            (Gria2), transcript variant 1, mRNA.
ACCESSION   NM_017261
VERSION     NM_017261.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6745)
  AUTHORS   Zhang,J., Liu,Z., Liu,X., Wang,X. and Yu,L.
  TITLE     Intravenous Injection of GluR2-3Y Inhibits Repeated Morphine-Primed
            Reinstatement of Drug Seeking in Rats
  JOURNAL   Brain Sci 13 (4), 590 (2023)
   PUBMED   37190555
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6745)
  AUTHORS   Han,J.X., Wen,C.X., Sun,R., Tang,M.Y., Li,X.M. and Lian,H.
  TITLE     The dorsal hippocampal CA3 regulates spatial reference memory
            through the CtBP2/GluR2 pathway
  JOURNAL   FASEB J 36 (9), e22456 (2022)
   PUBMED   35969153
  REMARK    GeneRIF: The dorsal hippocampal CA3 regulates spatial reference
            memory through the CtBP2/GluR2 pathway.
REFERENCE   3  (bases 1 to 6745)
  AUTHORS   Herguedas,B., Kohegyi,B.K., Dohrke,J.N., Watson,J.F., Zhang,D.,
            Ho,H., Shaikh,S.A., Lape,R., Krieger,J.M. and Greger,I.H.
  TITLE     Mechanisms underlying TARP modulation of the GluA1/2-gamma8 AMPA
            receptor
  JOURNAL   Nat Commun 13 (1), 734 (2022)
   PUBMED   35136046
  REMARK    GeneRIF: Mechanisms underlying TARP modulation of the
            GluA1/2-gamma8 AMPA receptor.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6745)
  AUTHORS   Schwarz,A.P., Kovalenko,A.A., Zakharova,M.V. and Zaitsev,A.V.
  TITLE     The application of the self-probing primer PCR for quantitative
            expression analysis of R607Q (un)edited GluA2 AMPA receptor mRNA
  JOURNAL   Biochem Biophys Res Commun 569, 174-178 (2021)
   PUBMED   34252589
  REMARK    GeneRIF: The application of the self-probing primer PCR for
            quantitative expression analysis of R607Q (un)edited GluA2 AMPA
            receptor mRNA.
REFERENCE   5  (bases 1 to 6745)
  AUTHORS   Pereyra,M., de Landeta,A.B., Dalto,J.F., Katche,C. and Medina,J.H.
  TITLE     AMPA Receptor Expression Requirement During Long-Term Memory
            Retrieval and Its Association with mTORC1 Signaling
  JOURNAL   Mol Neurobiol 58 (4), 1711-1722 (2021)
   PUBMED   33244735
  REMARK    GeneRIF: AMPA Receptor Expression Requirement During Long-Term
            Memory Retrieval and Its Association with mTORC1 Signaling.
REFERENCE   6  (bases 1 to 6745)
  AUTHORS   Hume,R.I., Dingledine,R. and Heinemann,S.F.
  TITLE     Identification of a site in glutamate receptor subunits that
            controls calcium permeability
  JOURNAL   Science 253 (5023), 1028-1031 (1991)
   PUBMED   1653450
REFERENCE   7  (bases 1 to 6745)
  AUTHORS   Nakanishi,N., Shneider,N.A. and Axel,R.
  TITLE     A family of glutamate receptor genes: evidence for the formation of
            heteromultimeric receptors with distinct channel properties
  JOURNAL   Neuron 5 (5), 569-581 (1990)
   PUBMED   1699567
REFERENCE   8  (bases 1 to 6745)
  AUTHORS   Sommer,B., Keinanen,K., Verdoorn,T.A., Wisden,W., Burnashev,N.,
            Herb,A., Kohler,M., Takagi,T., Sakmann,B. and Seeburg,P.H.
  TITLE     Flip and flop: a cell-specific functional switch in
            glutamate-operated channels of the CNS
  JOURNAL   Science 249 (4976), 1580-1585 (1990)
   PUBMED   1699275
REFERENCE   9  (bases 1 to 6745)
  AUTHORS   Boulter,J., Hollmann,M., O'Shea-Greenfield,A., Hartley,M.,
            Deneris,E., Maron,C. and Heinemann,S.
  TITLE     Molecular cloning and functional expression of glutamate receptor
            subunit genes
  JOURNAL   Science 249 (4972), 1033-1037 (1990)
   PUBMED   2168579
REFERENCE   10 (bases 1 to 6745)
  AUTHORS   Keinanen,K., Wisden,W., Sommer,B., Werner,P., Herb,A.,
            Verdoorn,T.A., Sakmann,B. and Seeburg,P.H.
  TITLE     A family of AMPA-selective glutamate receptors
  JOURNAL   Science 249 (4968), 556-560 (1990)
   PUBMED   2166337
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from M38061.1, AF164344.1,
            CO400088.1 and JAXUCZ010000002.1.
            
            On Apr 3, 2007 this sequence version replaced NM_017261.1.
            
            Summary: Glutamate receptors are the predominant excitatory
            neurotransmitter receptors in the mammalian brain and are activated
            in a variety of normal neurophysiologic processes. This gene
            product belongs to a family of glutamate receptors that are
            sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate
            (AMPA), and function as ligand-activated cation channels. These
            channels are assembled from 4 related subunits, Gria1-4. The
            subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R
            and R/G), which is thought to render the channels impermeable to
            Ca(2+), and to affect the kinetic aspects of these channels in rat
            brain. Alternative splicing, resulting in transcript variants
            encoding different isoforms (flip and flop), has been noted for
            this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) encodes isoform 1 (also known
            as the flip isoform). RNA editing changes Gln607Arg (CAG->CGG) and
            Arg764Gly (AGA->GGA).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF164344.1, X54655.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            undergoes RNA editing  :: PMID: 7992055, 12045112
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1227              M38061.1           1-1227
            1228-1413           AF164344.1         1147-1332
            1414-1916           CO400088.1         179-681
            1917-3605           AF164344.1         1836-3524
            3606-6745           JAXUCZ010000002.1  168247490-168250629 c
FEATURES             Location/Qualifiers
     source          1..6745
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q33"
     gene            1..6745
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /note="glutamate ionotropic receptor AMPA type subunit 2"
                     /db_xref="GeneID:29627"
                     /db_xref="RGD:61862"
     exon            1..518
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     CDS             431..3082
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; glutamate receptor B; AMPA-selective glutamate
                     receptor 2; glutamate receptor, ionotropic, AMPA 2"
                     /codon_start=1
                     /product="glutamate receptor 2 isoform 1 precursor"
                     /protein_id="NP_058957.1"
                     /db_xref="GeneID:29627"
                     /db_xref="RGD:61862"
                     /translation="MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAF
                     RVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITS
                     FCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLST
                     LQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVND
                     IVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIER
                     WSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP
                     AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV
                     DKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLA
                     AEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREE
                     VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR
                     FSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGG
                     VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRR
                     SKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCD
                     TMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKD
                     SGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNPQNIN
                     PSSSQNSQNFATYKEGYNVYGIESVKI"
     exon            519..659
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            660..899
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1096
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1150
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1312
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1480
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1585
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..1696
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1903
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..2274
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            2275..2473
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            2474..2721
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..2836
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            2837..3085
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..6745
                     /gene="Gria2"
                     /gene_synonym="GluA2; gluR-B; GluR-K2; GluR2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagactgcct gcccctctct gtgactttcc tgtgtgtgtg cgtgtgtgtg tatgtgtgtg
       61 tatgtgtgtg cgcgctcgtg tgagagagga gagagggaga agagagctcg agagagggtg
      121 attgtgtgag tgcatgggag ggtgctgata ttcccagaca ccaggactac agcggcagct
      181 cagctaaaaa ctgcattcag ccagtcctcg ggacttcggg agcagggaca ggacgcaagg
      241 catcaacagc caccagctac aactgggaaa taaggattct tctgccttca cttcgtgttt
      301 ttagcagctc cttgctaaat atcgacctca caatgcagag gatctaattt gctgaggaaa
      361 acagtcaaag aaggaagagg aagaaaggga aacgagggga tattttgtgg atgctctact
      421 tttcttggaa atgcaaaaga ttatgcatat ttctgtcctc ctttctcctg ttttatgggg
      481 actgattttt ggtgtctctt ctaacagcat acagataggg gggctatttc caaggggcgc
      541 tgatcaagaa tacagtgcat ttcgggtagg gatggttcag ttttccactt cggagttcag
      601 actgacaccc catatcgaca atttggaggt agccaacagt ttcgcagtca ccaatgcttt
      661 ctgctcccag ttttcaagag gagtctacgc aatttttgga ttttatgaca agaagtctgt
      721 aaataccatc acatcattct gtgggacact ccatgtgtcc ttcatcacac ctagcttccc
      781 aacagatggc acacatccat ttgtcatcca gatgcgacct gacctcaaag gagcactcct
      841 tagcttgatt gagtactacc aatgggacaa gttcgcatac ctctatgaca gtgacagagg
      901 cttatcaaca ctgcaagctg ttctggattc tgctgcagag aagaagtggc aggtgactgc
      961 tatcaatgtg gggaacatca acaatgacaa gaaagatgag acctacagat cgctctttca
     1021 agatctggag ttaaaaaaag aacggcgtgt aatcctggac tgtgaaaggg ataaagtaaa
     1081 tgacattgtg gaccaggtta ttaccattgg aaaacatgtt aaagggtacc attatatcat
     1141 tgcaaatctg ggattcactg atggggacct gctgaaaatt cagtttggag gagcaaatgt
     1201 ctctggattt cagattgtag actacgacga ttccctggtg tctaaattta tagaaagatg
     1261 gtcaacactg gaagagaaag aataccctgg agcacacaca gcgacaatta agtatacttc
     1321 ggccctgacg tatgatgctg tccaagtgat gactgaagca ttccgtaacc ttcggaagca
     1381 gaggattgaa atatcccgga gaggaaatgc aggagattgt ttggccaacc cagctgtgcc
     1441 ctggggacaa ggggtcgaaa tagaaagggc cctcaagcag gttcaagttg aaggcctctc
     1501 tggaaatata aagtttgacc agaatggaaa acgaataaac tacacaatta acatcatgga
     1561 gctcaaaaca aatggacccc ggaagattgg gtactggagt gaagtggata aaatggttgt
     1621 caccctaact gagctcccat caggaaatga cacgtctggg cttgaaaaca agactgtggt
     1681 ggtcaccaca atattggaat ctccatatgt tatgatgaag aaaaatcatg aaatgcttga
     1741 agggaatgag cgttacgagg gctactgtgt tgacttagct gcagaaattg ctaaacactg
     1801 tgggttcaag tacaagctga ctattgttgg ggatggcaag tatggggcca gggatgccga
     1861 caccaaaatt tggaatggta tggttggaga gcttgtctac gggaaagctg acattgcaat
     1921 tgctccatta actatcactc tcgtgagaga agaggtgatt gacttctcca agcccttcat
     1981 gagtcttgga atctctatca tgatcaagaa gcctcagaag tccaaaccag gagtgttttc
     2041 ctttcttgat cctttagcct atgagatctg gatgtgcatt gtgtttgcct acattggggt
     2101 cagtgtagtt ttattcctgg tcagcagatt tagcccctac gagtggcaca ctgaggaatt
     2161 tgaagatgga agagaaacac aaagtagtga atcaactaat gaatttggga tttttaatag
     2221 tctctggttt tccttgggtg cctttatgcg gcaaggatgc gatatttcgc caagatccct
     2281 ctctgggcgc attgttggag gtgtgtggtg gttctttacc ctgatcataa tctcctccta
     2341 cacggctaac ttagctgcct tcctgactgt agagaggatg gtgtctccca tcgaaagtgc
     2401 tgaggatctg tctaagcaaa cagaaattgc ttatggaaca ttagactctg gctccactaa
     2461 agagtttttc aggagatcta aaatcgcagt gtttgataaa atgtggactt atatgaggag
     2521 tgcagagccc tctgtgtttg tgaggactac cgcagaagga gtagccagag tccggaaatc
     2581 caaaggaaag tatgcctact tgctggagtc cacaatgaac gagtacatcg agcagaggaa
     2641 gccttgtgac accatgaaag tgggaggaaa cttggattcc aaaggctacg gcatcgccac
     2701 acctaaagga tcctcattag gaaccccagt aaatcttgca gtattgaaac tcagtgagca
     2761 aggcgtctta gacaagctga aaaacaaatg gtggtacgat aaaggtgaat gtggagccaa
     2821 ggactcggga agtaaggaaa agaccagtgc cctcagtctg agcaacgttg ctggagtatt
     2881 ctacatcctt gtcgggggcc ttggtttggc aatgctggtg gctttgattg agttctgtta
     2941 caagtcaagg gccgaggcga aacgaatgaa ggtggcaaag aatccacaga atattaaccc
     3001 atcttcctcg cagaattccc agaattttgc aacttataag gaaggttaca acgtatatgg
     3061 catcgagagt gttaaaattt aggggatgac cttgagtgat gtcatgagga gcaaggcaag
     3121 gctgtcaatt acaggaagta ctggagaaaa tggacgtgtt atgactccag aatttcccaa
     3181 agcagtgcat gctgtccctt acgtgagtcc tggcatggga atgaatgtca gtgtgactga
     3241 tctctcgtga ttgataggaa ccttctgagt gccttacaca atggtttcct tgtgtgttta
     3301 ttgtcaaagt ggtgagaggc atccgatatc ttgaaggctt ttctttcagc caagaattct
     3361 taactatgtg gagttcacct tgaattgtaa ggaaagataa attacaaaca gagcatcatt
     3421 ttctactccg atatcagagg aagcgtggtg gacatgcaca gctaacatgg aaatactatc
     3481 atttaactga agtctttgta cagacaacaa acccgtttcc gcagccacta ttgttagtct
     3541 cttgattcat aatgacttaa gcacacttga catcaactgc atcaagatgt gacctgtttt
     3601 ataaataaaa aggaaaaaaa catttaaaat aaaaaaatat ttttaggtat tttcacagac
     3661 aaactggctt ttaaataaat ttgcttccgt actggttggt taagacaaat acaaaaacaa
     3721 aaacaaaaca aaacaaaaac caaaaaaaac aaaacaaaac aaaacaaaaa ataaaaaaat
     3781 gataaagtca aactgagtgg gaagtgattg aaaaaaaggt ctgtggtatc agttccgtat
     3841 tttttcaaag ccaaatatgt aaatggtgag gaaggaaaca gaggagaatc cagtcgtgta
     3901 atttaatatt gttattaaaa ctttaatgta tcctattctt taacctttgg tgttaatatg
     3961 aaactacttg gtgatgcttg acatttgaaa taaacatttt tctattgttt tatttgcaag
     4021 tggtccaatt aattttgctt agctacagtt tggtcataaa tccagtgatc taaagacagg
     4081 aatgcatagt ccctaagatt cctaagaaaa ggcccccagt taaaagactg gaatattttt
     4141 tctctgacaa gtagaatttc ccccaaatag tctatgtaaa gctatttttt ctgtacatca
     4201 tactgtataa tagtaaaata tttgttaatt aaaaagcatt taatctatat agataaatgc
     4261 ttatagttta aaaatcagat ttattatcaa atgtcagaag gcgtgatttt ctgctcttga
     4321 agtatttaag gttgtgtagg agcagtaatc aatatagata aagtcagaaa tggcttgaag
     4381 gtatcaactg ttcagacacc cgtactggcc aaattctgta atctaagtat gcatcttcag
     4441 ttttaaaatt ataaaaacca acatcagttt ttgaatactt tagtgaccta gaaatagttt
     4501 ctttccattt ccatctataa aatcagccct aatttttatt tatgccccaa atagaagggg
     4561 cactttaata agtgtaatat ggatactctc ccatctctgt aactgttcac tgaagagatt
     4621 atactgtttt atttgatgaa tttaagccat ccatcttccc ttcattaaaa tgccttttat
     4681 ttttatttcc actaatgtgt tccaaatgag attagtttag ggttaaaagc acctgacaca
     4741 cagtagctat ctttaagatt tatgttattt ttttctcata aaaattctat gtaatatttg
     4801 gtgtctgacc aagtggttgg tagagcatcc ttattgacta tttttagaga tcagaaatgt
     4861 aagatttaac agtagccact tacattctac atggtaacat gtagttcgtg atgatcttca
     4921 ctaaatttta ccatccctcc tataaattcc gagatcattc aaaataattt gagtgcatta
     4981 ctcatcaggg atgctggagg tacattttaa gttttaataa taaatgctag aatgaccaaa
     5041 ttgcagacta attatttcca tattgtactt aaaattagtt tttaaaaatt attttaaaaa
     5101 aagatgacta tatacaatca atgctattta ttgtacctct gggcgtactc ttccaaaaat
     5161 tgagcttatc aatttttctc tgtcaagctt gaactaatgt aaataatcga aataatgtaa
     5221 agttatattt tcatgttttt atagatatga catgacaaga acatataatg taagagtatc
     5281 tcaagtgtgg ataatgttga ttggctaaca cagagctcag tcttaggcag taaaacctag
     5341 ttcaatatcc atgtaacaat gcatcagtat attgctgtat acatgtgtct gtgcatagaa
     5401 gtgataaatg ctcaaataag agtggtgaca gctatctcaa ggtttttttt aattcatttt
     5461 atataaactg ttatggaaag accaaaataa ttatgaacta ttcttatgta aatttacaat
     5521 tgtcctttaa tgtacatttt gtttacagta tagtacctta ttctctgctg tgttaagtgg
     5581 gtgtcgtact ccaaggagac aaacactttc tacaacttct attgaagaca ctgggatttc
     5641 caattttttc atgtgtacta tgtcagaaaa tgcttttgat tttattttta aatctaacat
     5701 ctgatggctt tttcagagtg ttgtggaaac ttcagtcata cataaaatat gttcttataa
     5761 aatgccaaca tctttttatt ctgtttttcc tcaatggtac aacaatctaa taatgagaaa
     5821 acagaaagtg tatcttatat tcttcccaaa taaatctaga tgtttgtagt gaaggagggc
     5881 atctctgctc agtttgttag aaaagtatga tagagtcaag gcagaatgtc tttttaattt
     5941 aaatgaagag aattggtcgt tgtggtacgt catgctcctt aagcactttg gacatagaga
     6001 gaaatgtggc aattgattaa atcaccaatt ctgcatacag gcattgtgta cttcagcctt
     6061 ccttgtgcag tcctctcatt tggtatggta ctcatattaa agagcaggga agtaacttgc
     6121 tttaaaatat ggtttgattt ttaaaaactg accatttatt atttgactta aaaattcttt
     6181 ccattttaac cagttttgac aaagctggtc atttgaatat ttacacaatc ctatttacat
     6241 gttctccaaa attattctaa catgacagtt ctaactttca cataaatttg tcaaagtttt
     6301 atatttaaat gtatcaggta tttaacacac caatataaag gcgaatctgc ttaaaataca
     6361 gtaattttac atttctaatc tgtaagtact atggatattt tgatgatcat gatggtattc
     6421 ggagaaaaag aagagaatta ctagcaatat tccggtaaaa aaaagttacc accaaccatt
     6481 tcttaatgat atcattaatt tttatttttc aattaagtgt acgtatgtgt gtgcctgctg
     6541 tgggaatgtg ccagtgagtg caggtgcctg ctgataacag gggtgaggcc aattatatca
     6601 gagctagagt tggggtgttc ataggtgttt gggagctccc aaatggtttg cgggaaacta
     6661 gcctgggtcc actgcaagtg ttctttctca aaccactgaa caattctcca gtaccaacaa
     6721 tatcattaaa ttttttttta aaaaa
//
