LOCUS       XM_008764638            8579 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus growth regulating estrogen receptor
            binding 1 (Greb1), transcript variant X1, mRNA.
ACCESSION   XM_008764638
VERSION     XM_008764638.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008764638.3.
            
            On Jan 21, 2021 this sequence version replaced XM_008764638.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8579
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8579
                     /gene="Greb1"
                     /note="growth regulating estrogen receptor binding 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 14 ESTs, 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 3 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:500633"
                     /db_xref="RGD:1564091"
     CDS             542..6409
                     /gene="Greb1"
                     /codon_start=1
                     /product="protein GREB1 isoform X1"
                     /protein_id="XP_008762860.2"
                     /db_xref="GeneID:500633"
                     /db_xref="RGD:1564091"
                     /translation="MGNSYAGQLKSTRFEEVLHNSIEASLRSNTLVPRPIFSQLYLEA
                     EQQLSSLEGGSRADNEEEEEDGEGGLDPSSPPNAYQLPPPPEGCCTTDGFCQAGKDLR
                     LVSISNEPIEVPAGFLLVGAKSPSLPDHLLVCAVDKRFLPDDNGHNALLGFSGNCVGC
                     GKKGFCYFTEFSNHINLKLTTQPKKQKHLKYYLVRNAQGALTKGPLICWKGSEFRSRQ
                     NSTNTCSSSLFPPLESSGSLAAFPTEPAPGTNPSVPVGAQQAGPASDHPSVATATGPA
                     VFNGKDSPKHPQLVKNSLCAAPRPTALGLLPNSGPPKKRHKGWSPESKSTTDGSFIQA
                     VGNRAKHEGASMPCVPQAGLVGPTSVTFPVVASSEPVSVPDNLLKICKAKPVIFKGHG
                     NFPYLCGNLNDVVVSPLLYTCYQNSQSLSRSYEQHGASTMQPISEETQLLLTVYYLVQ
                     LAADQVPLMEDLEQIFLRSWRESHLTEIRQYQQVPPQPFPPATSTAAPVTSAQLPWLA
                     GLAASSCNDSVHVIECAYSLAEGLSEMFRLLIEGKLSKTNYVVIICACRNAAIDSCIA
                     VTGKYQARILSESLLSPAEYQREVHYELVTGKVDSLGAFFSSLCPEGDIDILLDKFHQ
                     ENQGHVSSSFTASSTKKTAVLDASGVPMCTSYHQEPRGIRPFQLAVAQKLLSHVCSIA
                     DSSTQNLDLGSFEKVDFLICIPPSEVTYQQTVFHVWHSGVLLELGLEKEPVTKQRAEQ
                     HVLKLDTEAQARFKAFLQNSFQNPHTLFVLIHDHAHWDLVSSAVHNIYSQSDPSVGLV
                     DRLLNCREVKEAPNIVTLHVTSFPYALQTQHTLISPYNEIHWPISYSNGVDLYHESKK
                     YFGLSEFIDSTLSGHSLPLLRYDSSFEAMVTALGKRFPRLHSAVIRTFVLVQHYAAAM
                     MAVSGLPQMKNHTSVETLEITQNLLNSPKQCPCGHGLMVLLRVPCSPLAAVAYERLAH
                     VRARLALEEHFEIILGHPSSGITVGKHFVKQLKMWQKIEDAEWRPQTYLELEGLPCIL
                     IFSGMDPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNDIPLEKGPKNE
                     ALESDGEKLSSTDEDEEAGTEGCFEAGSTSEQRGPVKRERSHSHDSASSSLSSKASGS
                     VLYGESLVQPSGLPQGEFARSSPPCGPAEEGRAPGEIQRLRVSQGPTVISRHSPGLVP
                     QPDSSLRTGRRSLQVPAAPSSQLSSSSSGASSTCTVSTANVLVLQASQCSMAKACRQP
                     PIVFLPKLVYDMLLSTDSSGLPKSASLLPSPSVMWTSSFRPLLSKMMTSTEQSLYYRQ
                     WTVPRPSHMDYGNRAEGRVDSFHPRRLLLSGPPQIGKTGAYLQFLSILSRMLIRLTEV
                     DVYDEEEINTGLQEESDWHYLQLTDPWPDLELFQKMPFDYIIHDPKYEDASMICSHHQ
                     SIKSEDRGMSRKPEDLYVRRQTARMRLSKYAAYNTYHHCEQCQQYMGFHPHYQLSEST
                     LHVFAFSCSMLGEEIQLHFIIPKSKEYHFVFSQPGGQLESMRLPLVTDKSYEHIKSPT
                     FTPTTGRHEHGLFNLYHAMDGANHLHVLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAG
                     VGAAHFLIKELCYHNLELERNRQEELGVKPQDIWPFIVISDDSCVMWNVADVDCAGDR
                     SREFSWSERNVSLKHIMQHIEASPNITHYALIGMRKWASKTRSREVQEPFSRCHVHDF
                     IILNVDLTQNVQYNQNRFTCDDVDFNLRVHSAGLLLCRFNRFSVMKKQIAVGGHRSFH
                     ITSKVADSSVAIVPSQYICAPDSKHTFLAAPAQLLLEKFLQYHSHRFFPLSLKNHSHP
                     VLSVDCYLNLGPQISVCYVSSRPHSLNVSCSDMMFSGLLLYLCDSFVGASFLKKFHFL
                     KGATLCVICQDRNSLRQTVVRLELEEEWQFRLRDEFQTANAKEDRPLFFLTARHI"
ORIGIN      
        1 agtcatgagc acatggagag agaagtggga gaggagtcgg gagagagggg gaagagggta
       61 agggagcaag aggagaagag gagtgaggag ggggtaagta gccccttttg taataagtca
      121 ggtacacctg actgttgaca ggtaactgtg ggtcaacagt ggtactttat cacaacagca
      181 gaaaacaaat gccctaggga atggtgtcac ctccagtgga atgatcccct ctcttcaatt
      241 aatgaagttg gctacatttc tagaaggagg gacagctctc tctgctcttt gatcctggca
      301 cctagcccac aggatgacag ttgatcgagc tctatataaa tgaaagtagc tgcagagagc
      361 cgccctcttc tgtctggggc tgagcagagg ccgcaacccg ttccttcttg ctgctgctac
      421 ctactgctgc tgcggctgct ctgtttgcct ctccatcggg ctttgtgtgg agtcagccct
      481 tctccgcaaa actgaaatgt cattttaacc agaagactct tatcctctct gtgctctgga
      541 gatgggcaat tcttacgctg gacagctaaa gagcacgcgg tttgaagagg tcctccacaa
      601 ctccatcgag gcttccctac gctccaacac cctggtgccc cggcccatct tctcccagct
      661 gtatctggag gccgagcagc agttgtcatc attggaaggc ggcagccgag cggacaatga
      721 ggaagaagaa gaagatgggg aaggagggct agatcccagc agtcccccaa atgcctacca
      781 gctgccccct cctcctgaag gatgttgcac cacagatggc ttctgtcagg ctgggaagga
      841 cctacgtctt gtctccattt ccaatgagcc cattgaagtg cctgcaggct tcctcctggt
      901 gggtgccaag tctcccagcc tgccagacca cctcctggtg tgtgcagtgg acaagaggtt
      961 cttgcccgat gacaatggcc acaatgccct gctcggtttc tctgggaact gtgttggctg
     1021 tgggaaaaaa ggcttctgct atttcaccga attctccaac cacatcaacc tgaagctgac
     1081 cacgcagccc aagaaacaga agcacctcaa gtactatctg gttcgaaatg cacaaggggc
     1141 actgaccaaa ggacctttga tttgctggaa aggctctgag ttcagaagtc ggcagaactc
     1201 caccaacacc tgctccagtt ctctgttccc accactggag agttcagggt ccctggccgc
     1261 cttccccact gagcctgctc ctgggacaaa ccccagtgtc ccagtgggag ctcaacaggc
     1321 aggaccagcc tctgatcacc cctcagtggc cacagcaaca ggtcctgctg tcttcaatgg
     1381 caaggattcc cccaagcatc cacagctggt gaagaatagc ctgtgtgccg cgccgcgccc
     1441 cacagcctta ggtctcttgc caaactctgg gcctcccaaa aaacggcaca aagggtggtc
     1501 cccagagtct aaatcaacca cagatggcag cttcatccag gctgtcggca acagagctaa
     1561 acatgaaggt gccagcatgc cttgtgtacc ccaggctggc ttggtgggac caacttcagt
     1621 caccttcccg gtggtggcct ccagcgaacc agtgtcagtt ccggataact tgctgaaaat
     1681 atgcaaggcc aagccagtga tatttaaagg ccacgggaac ttcccctacc tctgcggaaa
     1741 cctgaatgat gtggtcgtca gccccctact gtacacctgc taccagaact cgcagtcact
     1801 ttccaggtcc tatgagcaac acggtgcctc caccatgcag cccatatctg aagagacaca
     1861 gctgttgctg accgtctact acctcgtcca gctggctgca gaccaggtgc cactgatgga
     1921 ggacctggag cagatcttcc tgcgctcctg gcgagagtca catctgacgg agataaggca
     1981 gtaccagcag gtgcctccac agcccttccc gccagccacc agcacagcag cgcctgtgac
     2041 ttctgcacag ctgccctggc tggcaggcct ggccgccagc tcctgcaatg acagcgtgca
     2101 tgttatcgaa tgcgcttact cgctggctga gggcctctcc gagatgttcc ggttgctcat
     2161 tgagggtaaa ctctccaaga ccaactatgt ggtcatcatc tgtgcctgcc gaaatgccgc
     2221 cattgactcc tgcatcgctg tcaccgggaa ataccaagcc cggattctct ccgagagcct
     2281 cctcagtcct gcagagtacc agagagaagt ccactatgag ctggtcactg gcaaagtgga
     2341 ctcgctgggg gccttcttta gcagcctctg tccagagggt gacattgaca ttttgctgga
     2401 caaatttcac caggaaaatc aaggccatgt ctcttcctca ttcactgctt cctctaccaa
     2461 gaaaacagcc gtgctggatg ccagtggggt tcccatgtgc acaagttacc atcaggagcc
     2521 acggggcatc cggccctttc agctggcggt ggcgcagaag ctcctttccc acgtgtgctc
     2581 aatcgcagat tccagcaccc agaatctgga cttggggtcc ttcgagaagg tggactttct
     2641 catttgcatt cccccatcag aggtgaccta ccagcagact gtgttccatg tctggcattc
     2701 aggggttctg ctggagctgg gcctggagaa agaacctgtt accaagcaga gggcggagca
     2761 acacgtcctg aaactagaca cggaggccca ggcaagattt aaggcctttc tgcaaaactc
     2821 cttccagaac ccacatacgc tctttgtcct catccacgac cacgcccact gggatctagt
     2881 gagcagtgct gttcataaca tctattctca aagtgaccca tctgtgggat tagtggacag
     2941 actgctcaac tgccgagagg tgaaagaggc gcccaacatt gtgactctcc atgtgacctc
     3001 cttcccgtat gcgctgcaga ctcagcacac gctcatcagc ccctacaatg agatccactg
     3061 gcccatctcc tacagcaatg gagtggacct gtatcatgag agtaagaagt actttgggct
     3121 gtctgagttt attgactcca ccctgtcagg acacagtctt cctctgctcc ggtatgacag
     3181 ctcctttgag gccatggtca ctgcattggg gaaaaggttc ccccgcctgc acagcgcggt
     3241 gatcaggacc tttgttcttg tgcagcacta tgcggccgcc atgatggccg tgagtggcct
     3301 cccacagatg aagaaccata catcagtgga gaccctagag atcacccaga acctcctcaa
     3361 ctccccaaag cagtgcccct gtggccacgg gctcatggtc ctgctgcgcg tgccctgttc
     3421 tcctctggca gctgtggcct atgagcgact ggcccatgtg cgggcacggt tggctctaga
     3481 agaacacttt gagatcattc tgggccaccc cagctccggc atcactgtag gcaagcactt
     3541 tgtgaagcag ctcaagatgt ggcagaaaat tgaggatgca gaatggaggc ctcagactta
     3601 cttggagttg gagggcctgc cctgcatcct gatcttcagt gggatggacc ctcatgggga
     3661 gtcgctgcca cggtctctga ggtactgtga cctgcgtcta ataaattctt cctgcctggt
     3721 gaggacagcc ctggagcagg aactgggtct ggctgcctac tttgttagca acgatatccc
     3781 cttggagaag gggcccaaga atgaggcctt ggagagtgac ggggagaagc tgagtagcac
     3841 agacgaagat gaggaggcag ggacagaagg gtgttttgaa gcaggctcca cctcagagca
     3901 gaggggccct gtgaagaggg aacgttccca ctcccatgac tccgcatctt catctctctc
     3961 ttccaaagcg tctggctcgg tgctctatgg tgagtccctg gttcagccct caggacttcc
     4021 acagggagag tttgcccggt catctccacc ctgtggccct gcagaggagg gcagggcccc
     4081 tggggagata cagcggctcc gagtgagtca gggacctaca gtcatcagta ggcacagccc
     4141 tggcctggtc ccacagcctg attctagcct caggactgga cggaggagcc tgcaggtgcc
     4201 agccgcccca tcctcccagc tgtcctcctc ctcctcgggc gcatcatcca catgcacggt
     4261 gtccactgcc aatgtgctag tccttcaagc ttctcagtgc tccatggcca aggcctgccg
     4321 gcagccaccc attgtcttcc tgcctaagct cgtgtatgac atgctcctgt ccactgacag
     4381 cagtggcttg cccaagtctg cctccctcct gccttcccct tcggttatgt ggaccagctc
     4441 cttccgcccc ctcctcagca agatgatgac gtcaactgaa cagtccctct actaccggca
     4501 gtggacagtg ccccggccca gccacatgga ctacggcaac agagctgaag gccgtgtgga
     4561 cagtttccac ccacgtaggc tgctgctcag tgggccacct cagattggga agacgggtgc
     4621 ctacctgcag ttcctcagta tcttgtccag gatgctgatt cggctgacag aagtggatgt
     4681 ttacgatgaa gaagagatca ataccggcct ccaagaggaa tcagattggc attacctcca
     4741 gctcaccgac ccttggcctg acctggagct cttccagaag atgccttttg attacatcat
     4801 tcatgacccg aagtatgagg atgccagtat gatttgttca caccaccaga gcatcaagag
     4861 tgaagacaga gggatgtcca ggaagccaga ggacctgtat gtgcggcgtc agacggcacg
     4921 tatgagactg tctaagtatg cggcatacaa cacataccac cattgcgagc agtgccagca
     4981 gtacatgggc ttccaccccc actaccagct ctctgagtcc accctgcacg tctttgcctt
     5041 ctcttgctcc atgctaggag aggagatcca gctccacttc atcatcccca agtccaagga
     5101 gtaccacttt gtcttcagcc aaccgggagg ccagctggag agcatgcgct tgcccctcgt
     5161 cacagacaag agttatgagc acatcaaaag cccgaccttc accccgacga caggccggca
     5221 tgagcatggg ctctttaatt tgtaccatgc gatggatgga gccaaccatc tacatgtgct
     5281 ggtggtcaaa gagtacgaaa tggccattta taagaagtac tggcccaacc acatcatgct
     5341 tgtcctccca agcatcttta acagtgctgg agtcggggct gcccacttcc tgatcaaaga
     5401 gctgtgctac cacaacctgg agctggagag gaaccggcag gaggagctgg gggtcaagcc
     5461 tcaggacatc tggcccttca tcgtcatctc cgatgactcc tgtgtgatgt ggaatgttgc
     5521 agacgtggac tgtgctggag accggagcag ggagttttcc tggtcagaga ggaatgtctc
     5581 tctgaaacac atcatgcagc acattgaggc gtcccctaac atcacacact acgccctgat
     5641 cggcatgcgg aagtgggcca gcaagacccg gagccgtgag gtgcaggagc ctttttcccg
     5701 atgccacgtg catgacttca tcatcctcaa cgtagacttg acccagaatg tacagtacaa
     5761 ccagaatcgg tttacatgtg acgacgtaga cttcaacctt cgcgtgcaca gtgctggcct
     5821 cctgctctgc cggttcaatc gcttcagcgt catgaagaag cagatcgccg tgggtgggca
     5881 ccggtccttc cacatcacat ccaaggtggc tgacagctct gtggccattg tgccttccca
     5941 gtacatctgt gccccggaca gtaagcacac attcctggca gctcccgccc agctcctgct
     6001 ggagaagttc ctccagtacc acagccaccg cttcttcccg ctgtctctga agaaccacag
     6061 ccaccccgtg ttgtctgtag actgctacct taacctgggg cctcagattt ctgtttgtta
     6121 tgtcagctcc aggccccact ccttaaacgt cagctgctct gacatgatgt tcagcgggct
     6181 cctgctgtac ctctgcgact cttttgtggg ggctagcttc ttgaagaagt tccattttct
     6241 gaaaggagcc accttgtgcg tgatctgcca agaccggaac tcgcttcgac agacggtggt
     6301 ccgcctggag ctagaagagg agtggcagtt ccggctgcgg gatgagttcc agacagccaa
     6361 tgccaaggaa gacaggccac tctttttcct cactgcaaga cacatctgag agacacagat
     6421 gccggcagag ctcccgagag tgtgaggtcg tcaggaccca cctgccactg aggctactga
     6481 aggtgccagt ctaaggggta taagaactcc agcataccca gagatggcca tgcacagcct
     6541 cttgtgacac atgtcacaat gtcctgtggc agataatgac ttagagccac aggcaggagt
     6601 ccttgatagg caggcctgaa aaccaaagac tactgtgttc tgggctggac cgcatgccct
     6661 gagctgtcct gaagtccgtt atatgcagaa tgaagtttcg ctaagtctgc tgtcatccat
     6721 atgcttccgt ggacaaattc gatttgctct agagaacctt gggttgtcgg gtcacggtgc
     6781 ctgtgactat gatttcacaa agtaggtttc ctataactcc ctacagagca atattccaaa
     6841 ggaacatttt aactgtaaag gctggtgaca agaagacaaa agagcagatc attttaataa
     6901 gaattattta atcacctaca agtttacttt gcaggagcta gcccaaaggc atcaaattta
     6961 atatgattaa aatgaattgc tttaccttag aaacgatgtg actctattca aatagtatgg
     7021 ggtaaatacc ctacctctta taaagggcaa aatggagaag aagttttctt acaaaccaaa
     7081 agggctttag ggaggaaatt agggttgtag ctgtggactg aagagttgcc ttccgaagga
     7141 aagaggacca cattgcttac atgataaaaa aataagaaaa accaaagaga tacaggagac
     7201 aatgaaaaga gctggagcaa tggctcggct gtgtaagttc aatcctgagg actgtaagtg
     7261 tgtgctgttc aatcctgagg actgtaagtg tgtgctgttc aatcctgggg actgtaagtg
     7321 tgtgctgttc aatcctgggg actgtaactg tgtgctgttc aattctgggg actgtaagtg
     7381 tatgctgttc aatcctgggg actgtaagtg tgtgctgttc aatcctgggg actgtaactg
     7441 tgtgctgttc aatcctgggg actgtaagtg tgtgctgttc aatcctgagg actgtaagtg
     7501 tgtgctgttc aatcctgggg actgtaagtg tatgctgttc aatcctgagg actgtaagtg
     7561 tgtgctgttc aatcctgggg actgtaagtg tgtgctgttc aatcctgagg actgtaagtg
     7621 tgtgctgttc aatcctgggg actgtaagtg tgtgctgttc aatcctgggg actgtaagtg
     7681 tgtgctgttc aatcctgagg actgaaattc ggatgccacc acgcacataa caagccacat
     7741 attctgcaaa tgcctgtaat tccagccctg agagatttga tgctttcttc tgtcctctct
     7801 gtatctcagg tgtggcgcat gagtgtgttc tctctctctc tctctctctc tctctctctc
     7861 tctctctctc taaaaaacaa aacaacaaaa acagttaaga accagatttg taatttcttg
     7921 aagttcactt ttcagtgaga tcaacctgtg ttctcttact catcttggtt catttaggga
     7981 tagtctgggc ttctcagaaa atgtggaacc ggagagaaac aagtggctgt gcattaatta
     8041 ctgtgatggt gtttaagtcg atgccacctg ttagtctgtt ggtgtctggt tttcctgaat
     8101 ccatgaatga aagatgaata gattacaatg cagagaatac agactttggg aagaagcagg
     8161 accacaattc aaaccccaca gttcagctcc atcccaaacc acggcacatc aggagctaag
     8221 ggaaacacgg gttgctgaaa agttaatcag gacacagtcg cctgtgcaca cttagacacg
     8281 gctgagcact gtgtgtggta agagttcaag gagaaacctg tccaaataga tgccaaagat
     8341 ttcactgcta acctttttcc ccaaggaaga aagtatgcaa gtataaaaca tttccatcaa
     8401 tgtttataaa acaatcgtct gtgaatgtcg tgattcctgt tttgtaacaa aagctgatct
     8461 cctctagttc agtttgtctt ctgtaaatag cggctcctat gccattctcc cctttctatt
     8521 agttaattta aacgaacact ctcgactgtt ctagtcttat aaataaaacg tatagtgca
//
