LOCUS       NM_001034944            1288 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus GRB2-related adaptor protein 2 (Grap2), mRNA.
ACCESSION   NM_001034944 XM_345859
VERSION     NM_001034944.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Tanase CA.
  TITLE     Histidine domain-protein tyrosine phosphatase interacts with Grb2
            and GrpL
  JOURNAL   PLoS One 5 (12), e14339 (2010)
   PUBMED   21179510
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  AUTHORS   Yamasaki S, Takase-Utsugi M, Ishikawa E, Sakuma M, Nishida K, Saito
            T and Kanagawa O.
  TITLE     Selective impairment of FcepsilonRI-mediated allergic reaction in
            Gads-deficient mice
  JOURNAL   Int Immunol 20 (10), 1289-1297 (2008)
   PUBMED   18664516
REFERENCE   3  (bases 1 to 1288)
  AUTHORS   Saito T, Ji G, Shinzawa H, Okumoto K, Hattori E, Adachi T, Takeda
            T, Sugahara K, Ito JI, Watanabe H, Saito K, Togashi H, Ishii K,
            Matsuura T, Inageda K, Muramatsu M and Kawata S.
  TITLE     Genetic variations in humans associated with differences in the
            course of hepatitis C
  JOURNAL   Biochem Biophys Res Commun 317 (2), 335-341 (2004)
   PUBMED   15063762
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC105895.1.
            
            On Oct 21, 2005 this sequence version replaced XM_345859.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105895.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN06680412
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1288
                     /gene="Grap2"
                     /note="GRB2-related adaptor protein 2"
                     /db_xref="GeneID:366962"
                     /db_xref="RGD:1307605"
     exon            1..113
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     exon            114..205
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1108
                     /gene="Grap2"
                     /codon_start=1
                     /product="GRB2-related adapter protein 2"
                     /protein_id="NP_001030116.1"
                     /db_xref="GeneID:366962"
                     /db_xref="RGD:1307605"
                     /translation="MEAIAKFDFMASGEDELSFHTGDILKILSNQEEWLKAELGSQEG
                     YVPKNFIDIKFPEWFHEGLSRHQAENLLMGKEIGFFVIRASQSSPGDFSISVRHEDDV
                     QHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQIFLRDGTQDQQGHRGNSL
                     DRRTQGGPPREVPSGTAGEEIRPLMNRKLSDHLPLGTQQFHPHQQLPPQFPPGPQPPP
                     QQRYLQHFHQDRRGGSLDINDGHLGIGSEMNATLMHRRHTDPVQLQAAGRVRWARALY
                     DFEALEEDELGLRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR"
     exon            206..297
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     exon            298..417
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     exon            418..586
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     exon            587..811
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     exon            812..928
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1264
                     /gene="Grap2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcgcggta aacttgacat ttgagtgcat cttcccaccg gcaaaagacg aacctaataa
       61 ctcgttgtca aagccgagat acacactcaa ctcaggctct tcgcttccca aagcttctcg
      121 tcaagacatg gaagctattg ccaagttcga tttcatggcc tcgggtgagg acgaattgag
      181 ctttcacact ggagatattc tgaagatcct aagcaaccag gaggagtggc tcaaggcgga
      241 gcttggaagc caagaaggat atgtgcctaa gaattttata gatatcaagt ttcctgagtg
      301 gttccatgaa ggcctctctc gacatcaggc agaaaactta ctcatgggca aggaaattgg
      361 attcttcgtc atcagggcca gtcagagttc accaggagac ttctccatct ctgtcaggca
      421 tgaggacgat gttcagcact tcaaagtcat gcgagacacc aagggcaatt acttcctgtg
      481 gactgagaag ttcccatccc taaataagct ggtggactac taccggacaa cttccatctc
      541 caaacagaag cagatcttcc ttcgggatgg aacccaagat cagcagggtc accggggcaa
      601 cagcctggac aggagaaccc agggaggccc tcccagggag gttccaagtg ggaccgcagg
      661 agaagaaatc cgacccttga tgaaccggaa gctgtcagac caccttcctc tgggtaccca
      721 gcagttccac ccgcaccagc aactgccccc ccagttccca ccagggcccc agccccctcc
      781 acagcagcgc tatctgcagc attttcacca ggaccgtcgt ggaggcagcc tggacataaa
      841 cgatggacac ctcggcattg gcagtgagat gaatgccacc ctgatgcacc ggagacatac
      901 agaccccgta caactccagg cggcagggcg agtgcgctgg gccagggcac tctatgactt
      961 tgaggccctg gaggaagatg agctggggct cagaagtgga gaggtggtcg aagtcctgga
     1021 cagctccaac ccgtcttggt ggaccggccg cctgcacaac aaactgggtc tcttccctgc
     1081 caactatgtg gcccccatga tgcgatgagt catgctggga ggcttagggg cttttcgtct
     1141 gaagcctcct gcaagatgga ggcaaggggg aaaagctgaa ctcaataact acacatacat
     1201 gcatacatgt gcatgtgtgc gcctgtgtac acacaacatg tatatgtacg cctatgtcta
     1261 cacaaaaaaa aaaaaaaaaa aaaaaaaa
//
