LOCUS       NM_001191826            3753 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus GRAM domain containing 1C (Gramd1c), mRNA.
ACCESSION   NM_001191826 XM_340988
VERSION     NM_001191826.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3753)
  AUTHORS   Sandhu,J., Li,S., Fairall,L., Pfisterer,S.G., Gurnett,J.E.,
            Xiao,X., Weston,T.A., Vashi,D., Ferrari,A., Orozco,J.L.,
            Hartman,C.L., Strugatsky,D., Lee,S.D., He,C., Hong,C., Jiang,H.,
            Bentolila,L.A., Gatta,A.T., Levine,T.P., Ferng,A., Lee,R.,
            Ford,D.A., Young,S.G., Ikonen,E., Schwabe,J.W.R. and Tontonoz,P.
  TITLE     Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER
            Cholesterol Transport in Mammalian Cells
  JOURNAL   Cell 175 (2), 514-529 (2018)
   PUBMED   30220461
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Oct 7, 2022 this sequence version replaced NM_001191826.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.422202.1,
                                           SRR26360181.2104968.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                JAXUCZ010000011.1  70140930-70141018
            90-236              JAXUCZ010000011.1  70144830-70144976
            237-321             JAXUCZ010000011.1  70158689-70158773
            322-425             JAXUCZ010000011.1  70168254-70168357
            426-521             JAXUCZ010000011.1  70168891-70168986
            522-602             JAXUCZ010000011.1  70170580-70170660
            603-721             JAXUCZ010000011.1  70184877-70184995
            722-854             JAXUCZ010000011.1  70188155-70188287
            855-1017            JAXUCZ010000011.1  70191491-70191653
            1018-1155           JAXUCZ010000011.1  70200067-70200204
            1156-1274           JAXUCZ010000011.1  70211190-70211308
            1275-1417           JAXUCZ010000011.1  70215550-70215692
            1418-1521           JAXUCZ010000011.1  70216436-70216539
            1522-1698           JAXUCZ010000011.1  70217851-70218027
            1699-1756           JAXUCZ010000011.1  70218700-70218757
            1757-1867           JAXUCZ010000011.1  70221215-70221325
            1868-1973           JAXUCZ010000011.1  70221570-70221675
            1974-3753           JAXUCZ010000011.1  70222699-70224478
FEATURES             Location/Qualifiers
     source          1..3753
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..3753
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /note="GRAM domain containing 1C"
                     /db_xref="GeneID:360717"
                     /db_xref="RGD:1305433"
     exon            1..89
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..2054
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /note="GRAM domain-containing protein 1C"
                     /codon_start=1
                     /product="protein Aster-C"
                     /protein_id="NP_001178755.1"
                     /db_xref="GeneID:360717"
                     /db_xref="RGD:1305433"
                     /translation="MEGALTARQIVNDGDSSLATELQGELEENSSPAVDESIVSAKKQ
                     GPSTHNWSGDWSFWISSSTYKDRNEEYRQQFTHLPDSEKLIADYACALQRDILLQGRL
                     YLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFG
                     ARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMEHLSLSIEENVQ
                     PRSPGRSSVDDSGERDEKFSKAISLTHESVSRASETESLDGNSPERGLGKEGSQSERH
                     VRKSPSLASEKKLGRVPSKTLDLNKNEYLSLDKSSTSDSVDEENIPEKDLQGRLYINR
                     VFHISAERMFELLFTSSHFMQRFTNSRNIIDVVSTPWTVESGGDQLRTMTYTIVLSNP
                     LTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCR
                     LRVSTDLKYRKQPWGLIKSLIEKNSWSSLENYFKQLESDLLMEESVLSQPMEDAGKLS
                     SLRRRRRTLNRTAEPVPKLPSQRSPTDLGFEAKDDITGKRKAVDSCDTALIVVMSVFL
                     LLLVLLNVTLFLKLSKIEHATQSFYQLHLQGEKSLNLVSDRLSRTENIQKNKDQAHRL
                     KGVLQDSIVMLEQLKSSLIMLQKTFDLLNKNKSGVVVES"
     exon            90..236
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            237..321
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            322..425
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            426..521
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            522..602
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            603..721
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            722..854
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            855..1017
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1155
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1274
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1417
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1521
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1698
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1699..1756
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1867
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..1973
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..3753
                     /gene="Gramd1c"
                     /gene_synonym="RGD1305433"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctcccgcc ccggagctct cagggacgcg cgtgcggggt gccgccgcgg gagggtgccg
       61 cgatggaggg cgctctgacg gcccgccaga tagtaaacga cggggattca agtcttgcca
      121 cggagctaca gggagagttg gaggaaaatt ctagcccggc tgtggatgag agtatagttt
      181 cagccaaaaa acagggacca agcacacaca attggagcgg cgactggagc ttttggatct
      241 cgagctccac ctacaaagac aggaacgagg aatacaggca gcagttcaca cacctgcccg
      301 actccgaaaa gctgatagca gattacgctt gcgctcttca gagggatatc ttgcttcagg
      361 ggaggctgta cctttcagaa aactggctgt gtttctatag caacatcttc agatgggaaa
      421 ccacaatttc tattgcttta aagaatataa cctttatgac caaggagaaa actgctcgac
      481 tcatcccaaa tgctatccag atcatcacag agggggaaaa gtttttcttc acgtcttttg
      541 gtgccagaga cagaagttac ctgagcatat ttaggttgtg gcagaatgta ttgctagata
      601 agagcctgac cagacaggag ttctggcaat tgctccagca gaactatggc accgaactag
      661 gattaaacgc tgaagaaatg gaacacttgt cgctatcaat tgaagaaaac gtgcagccaa
      721 gaagtccagg aagaagcagc gtggatgact ctggggaaag agacgagaag ttctccaagg
      781 ccatcagttt gacacacgag tcagttagca gagcttcaga aacagagtca ttggatggaa
      841 actcaccgga aagaggatta ggaaaagagg ggtctcagag tgagagacac gtgagaaaaa
      901 gtccttccct agcttcagaa aagaagttag gcagagtgcc ctccaagaca ctggacttga
      961 ataagaatga gtacctttct ctggacaaga gcagtacttc agattctgtg gatgaagaaa
     1021 atattcccga gaaagatctt caaggaagac tctatatcaa ccgagttttt cacatcagtg
     1081 ctgagagaat gtttgaattg ctcttcacca gctcacactt tatgcagaga tttactaatt
     1141 ctagaaacat aatagatgtg gtgtccaccc cctggacagt tgaatctgga ggcgatcagc
     1201 tgagaaccat gacctacact atagtcctca gcaatccact tacgggcaaa tgtactgccg
     1261 ccacggaaaa gcagacactg tataaagaga gccgggaagc ccagttttat ttagtagatt
     1321 cagaagtgct gacacacgac gtcccctacc acgactactt ctacactttg aatagatact
     1381 gcatcgtgcg ctctgcaaaa cagaggtgca ggctgagagt ctccacagac ttgaaataca
     1441 ggaaacaacc gtggggcctt atcaagtctt taatcgagaa gaattcctgg agttcgctgg
     1501 agaactattt caaacagctt gaatcagatt tgttaatgga agagtctgtg ttgagtcaac
     1561 ccatggaaga tgctggaaaa cttagcagcc tacgccggag acggcggacc ttgaaccgga
     1621 cagcagagcc ggttccaaag ctgccctctc agcgctctcc tacagatttg ggcttcgagg
     1681 ccaaagacga tattacagga aagagaaagg cagtggacag ttgtgacact gcccttatcg
     1741 tggtgatgag cgtatttttg ctgctgctag ttctgctgaa tgtgacactg tttctgaagt
     1801 tgtcaaagat agaacacgcc acccagtcct tctaccagct tcacctccaa ggagagaaat
     1861 ctttaaattt agtctctgac aggctctcaa gaacggaaaa tattcaaaag aacaaagatc
     1921 aggcccaccg tttaaaagga gtactccagg attccatagt gatgttggaa cagctgaaga
     1981 gctcactcat tatgcttcag aaaacctttg atttactaaa caagaacaag tctggggtgg
     2041 ttgtggagag ctagtgctga aatgtggaga tcaaagagac atctggacct agaagacaac
     2101 atctggaagg aaacagagga tgaagactgt cgcggtcaaa aggacatttc tgatcttttt
     2161 attaccggga tttctactag aaaagcctta tttaaataac atttactcag tgattctcac
     2221 cagtagcctt aagactctat cttttcactt cttatagcta ttttcaagct gtgaatttct
     2281 ctagtgaacc atgaaatata ttttggaatt gaaattctgt gacacaaaag gggggaagga
     2341 agacaccctg gctacagtgg cttctcttct ccagtgaggc ttgtcacttg atcctttaaa
     2401 tttacgttag cacagagtcc ctgtgcccag tggggtgtgt tcatagctga gtctaagagc
     2461 ctaaaaaggt aagaaggaac cctttaatca cttgtcacct taaaggatca ttttccaagt
     2521 gcagacattg caggtttgta tctttaaact ttacaatgtc ttcattgact tggcttcaag
     2581 gccagtggtc agaccttttg tatgtctgaa agagtcattg accatgttgt atcttaatga
     2641 aggaatatat gtgtatgtat acacacatac atatatatat atatatatac atgtacataa
     2701 atgtgtgtat atgtatatat gtatgtaggt acatatttat atctaccaaa ggtgagatta
     2761 cccttcatac atccaaaaga ctgaatagta atttaggaga aggaagtatt cgagttatta
     2821 atgctcagaa tgaactactt ttagttttag aagccataag attattataa agtctgggca
     2881 tttcatgatg gatcaaatga gaccatgaat tatgcttgga ttcaccttag gagggcccat
     2941 aatggaagtg acccatgcca tggaaaagaa ttgatggctt ttcagtagca gctacataca
     3001 gcttcattct ttattcttca ttctgtgtgt agcttgtctt gctggcaatc agaagataga
     3061 cagacagata ctcgcactcg ccagtaaaga ctgggggacg tgcgtgctga ctgaagttga
     3121 gaggcacaag cttgggctct caggacagct gcttaggcat ttgtgaaaag aaggactctg
     3181 tgaccagact tgaaattagc tccgtccccc aggatttagg gaatgttcag gacatattta
     3241 tttattgttt tgttctctag aggtctttct agaacacgca catatattta ttcttattga
     3301 atatccattg tctttaagtc aatgttgcct ttccctcagg tcaccaaagc caaatgtcat
     3361 tgttaacaac gcttttgcga agcctgtagg gaataaaaat actggctaaa gggaagggtt
     3421 tctcttcaca agtcctatct actctccctg gggaaggggg cttcagagta atacctcctg
     3481 ttccgttttg tcttgttttg ttttgtttgt ttaggaacat aggaagtatc tggctgtatg
     3541 ttagagtgag tggattagaa acttcaaatt gttacattta gaaaaatgtt aactgtcaga
     3601 gtgaatgttt ttgttgtttc tctcagacta ctttatcaca tacctcaaag gttaccaacg
     3661 ttgctttgta gataaaacac taaatatgta tgtagaatta agatcttaat ctgttatata
     3721 tagattgact tcaataaaac ccaaaatgtc taa
//
