LOCUS       NM_001191616            2831 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus GRAM domain containing 1B (Gramd1b), mRNA.
ACCESSION   NM_001191616 XM_217113
VERSION     NM_001191616.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2831)
  AUTHORS   Sandhu,J., Li,S., Fairall,L., Pfisterer,S.G., Gurnett,J.E.,
            Xiao,X., Weston,T.A., Vashi,D., Ferrari,A., Orozco,J.L.,
            Hartman,C.L., Strugatsky,D., Lee,S.D., He,C., Hong,C., Jiang,H.,
            Bentolila,L.A., Gatta,A.T., Levine,T.P., Ferng,A., Lee,R.,
            Ford,D.A., Young,S.G., Ikonen,E., Schwabe,J.W.R. and Tontonoz,P.
  TITLE     Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER
            Cholesterol Transport in Mammalian Cells
  JOURNAL   Cell 175 (2), 514-529 (2018)
   PUBMED   30220461
REFERENCE   2  (bases 1 to 2831)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jul 17, 2010 this sequence version replaced XM_217113.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.22617.1,
                                           SRR26643292.33118.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-465               JAXUCZ010000008.1  49718482-49718946   c
            466-543             JAXUCZ010000008.1  49675322-49675399   c
            544-754             JAXUCZ010000008.1  49592612-49592822   c
            755-775             JAXUCZ010000008.1  49586388-49586408   c
            776-860             JAXUCZ010000008.1  49575419-49575503   c
            861-964             JAXUCZ010000008.1  49574757-49574860   c
            965-1060            JAXUCZ010000008.1  49573645-49573740   c
            1061-1141           JAXUCZ010000008.1  49572915-49572995   c
            1142-1257           JAXUCZ010000008.1  49569537-49569652   c
            1258-1414           JAXUCZ010000008.1  49567671-49567827   c
            1415-1604           JAXUCZ010000008.1  49566365-49566554   c
            1605-1748           JAXUCZ010000008.1  49565935-49566078   c
            1749-1867           JAXUCZ010000008.1  49564837-49564955   c
            1868-2010           JAXUCZ010000008.1  49564428-49564570   c
            2011-2114           JAXUCZ010000008.1  49563177-49563280   c
            2115-2318           JAXUCZ010000008.1  49562430-49562633   c
            2319-2409           JAXUCZ010000008.1  49561587-49561677   c
            2410-2517           JAXUCZ010000008.1  49558045-49558152   c
            2518-2635           JAXUCZ010000008.1  49557655-49557772   c
            2636-2831           JAXUCZ010000008.1  49556332-49556527   c
FEATURES             Location/Qualifiers
     source          1..2831
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..2831
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /note="GRAM domain containing 1B"
                     /db_xref="GeneID:300644"
                     /db_xref="RGD:1305443"
     exon            1..465
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..2725
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /note="GRAM domain-containing protein 1B"
                     /codon_start=1
                     /product="protein Aster-B"
                     /protein_id="NP_001178545.1"
                     /db_xref="GeneID:300644"
                     /db_xref="RGD:1305443"
                     /translation="MPAANMMENLQLPALQVPEPQGAPEGSAVWSSSSTPTLRRRRFK
                     MRRMKNVQEQSLEAGLVAPDLPGVLAPGKEFLQLPSIEITPSSDEDTPWSNCSTPSAS
                     PRRKRFLLRKWLRVRERKECSESSSQQSSQQSSHDDDSSRFLSPRVREESTASNSNRS
                     TPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGG
                     KNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLS
                     ENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARD
                     RTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYC
                     EEIPIEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDGLPLEE
                     EVMEGDGSLEKELAIDNIIGEKIEIMAPVTSPSLDFNDNEDIPTELSDSSDTHDEGEV
                     QAFYEDLSGRQYVNEVFNFSVDKLYDLLFTTSPFLRDFMEQRRFSDIIFHPWKKEENG
                     NQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYT
                     INRYTLTRVARNKSRLRVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTKT
                     ESTYLAEIHRQSPKEKTNKSSAVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIK
                     HVAGSTQTRHIPEDTPDGFHLQSVSKLLLVISCVLVLLVILNMMLFYKLWMLEYTTQT
                     LTAWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQRWREIIKSSVMLLDQMKDSLIN
                     LQNGIRSRDYTAESDEKRNRYH"
     exon            466..543
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            544..754
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            755..775
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            776..860
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            861..964
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1060
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1141
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1257
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1414
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1604
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1748
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1867
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..2010
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2114
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2318
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            2319..2409
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            2410..2517
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            2518..2635
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
     exon            2636..2831
                     /gene="Gramd1b"
                     /gene_synonym="RGD1305443"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgccacgggc cccggggtag ggagccgaga gagggagcct cgagccaggc tgcagaagga
       61 gggcaccggg cagcggccag ggaccccgat gccggcagcc aacatgatgg agaacctgca
      121 gctgcccgcc ctgcaggtgc cagagcctca gggcgcgccg gagggcagcg cggtgtggtc
      181 cagctcgtcc acccccacgc tccgccgccg gcgctttaag atgcgccgga tgaagaacgt
      241 gcaggagcag agcctggagg cggggctggt agccccggac ctaccgggcg tcttggcccc
      301 cggcaaggag ttcctgcaac tgccgtccat tgagattacg ccctccagcg acgaggacac
      361 cccgtggtcc aactgttcca cacccagcgc gtccccgcgc cgaaaacgct tcctgctccg
      421 caagtggctg agggtgaggg agcggaagga gtgcagtgag agcagcagcc agcagagcag
      481 ccagcagagc agccacgacg atgattccag caggttcctg agtcctcgag tgcgcgaaga
      541 aagcactgcc agtaactcca accgcagcac gccggcctgc tctcccatcc tccggaagcg
      601 gtcccgctca ccaacaccac agaaccagga cggagacacc atggtggaaa agggctcaga
      661 tcactcctcg gacaagtccc catccacccc agagcagggt gtgcaacgca gttgctcctc
      721 acagtctggt cggagcggtg gtaaaaattc caagaaaagc cagagttggt acaatgtgct
      781 aagccccact tacaagcaga gaaatgaaga cttcagaaag ctcttcaagc aactcccaga
      841 cacggagcgc ctcattgttg attactcttg tgcactccaa agagacattc ttcttcaggg
      901 ccgactctac ctctcagaga attggatctg cttctacagc aacatcttcc gctgggaaac
      961 tctgctgaca gtccgtttga aagatatctg ctccatgact aaagagaaaa cagctcgcct
     1021 cattcccaat gccatccaag tctgcactga ttcagaaaag cactttttta cttcatttgg
     1081 agcccgggat aggacgtaca tgatgatgtt ccggctctgg cagaatgctc tcctcgaaaa
     1141 gcccctgtgc cccaaggagc tctggcactt tgtccaccag tgctacggga acgagctggg
     1201 tctaaccagt gatgacgagg actacgtgcc tccagacgat gacttcaaca cgatgggcta
     1261 ctgcgaggag atccccatag aagagaatga ggtgaatgac agctcatcca aaagcagcat
     1321 agagaccaag ccggatgcca gcccacagct gcccaagaag tctatcacca acagcacact
     1381 gacatctacg ggaagcagtg aagcccccgt ctcgtttgat ggcttgccgt tggaggaaga
     1441 ggtgatggag ggtgacgggt ccctagagaa ggaacttgcc attgacaaca tcatagggga
     1501 gaagatcgag atcatggcgc ctgtgacctc cccttcacta gacttcaatg acaatgagga
     1561 tatccccacc gagctcagtg attcttcaga tacccacgat gaaggagagg tccaggcctt
     1621 ctatgaggac ctaagtggaa gacagtatgt gaacgaagtc ttcaacttca gcgtggacaa
     1681 actctatgac ctgctgttca ccacctcacc ctttctgcgg gacttcatgg agcagcggcg
     1741 cttctctgat atcatcttcc acccatggaa aaaggaggag aatggaaacc agagtcgagt
     1801 gattctctac actatcaccc ttactaatcc tctggctccc aaaacggcca ctgtcaggga
     1861 gacacagacc atgtacaaag caagtcagga gagcgagtgc tatgtgatag acgccgaagt
     1921 cctcacccac gatgtgccat accacgacta cttctatacc atcaatcgat acacactcac
     1981 cagagtggcc cggaacaaga gcagactcag ggtctccaca gagctccgct atcgaaaaca
     2041 gccctggggg tttgtgaaaa ctttcatcga gaagaacttc tggagtggac tggaggacta
     2101 cttccgccat ttagagactg agctaaccaa aaccgagagt acctacttgg ccgagataca
     2161 cagacagtcg cccaaggaga agaccaataa gtcctcagca gtccggagga ggaagcgtcc
     2221 ccatgcccac ctgcgggtac ctcatctgga agaggtgatg agtcctgtca ccacccccac
     2281 agatgaagat gtgggccaca ggatcaagca cgtggcaggt tccacgcaga cacggcatat
     2341 cccggaggac actcctgatg gttttcatct gcaaagcgtg tccaagctgc tgctggttat
     2401 cagctgtgtt ctggtgctgc tggtcatcct taacatgatg ctcttttaca agctgtggat
     2461 gctggaatac accacacaga cgctcactgc ctggcagggt ctcagactcc aggaaaggtt
     2521 accccagtct cagacagaat gggcccagct attagaatcc caacaaaagt accacgacac
     2581 cgagctccag aggtggaggg aaatcatcaa atcctcagtg atgctccttg accagatgaa
     2641 ggactctctt atcaaccttc agaacggtat ccggtcccga gactacacag ctgagagcga
     2701 cgagaagagg aaccgctatc actgacaagg caggaccagg ggtggctaca agaggcctgt
     2761 gcaatacatg tacatagacc ctataaatat atataaatat atatatatac agaatataaa
     2821 tatatattat a
//
