LOCUS       NM_001399636            2960 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus GRAM domain containing 1A (Gramd1a), transcript
            variant 1, mRNA.
ACCESSION   NM_001399636 XM_006228833
VERSION     NM_001399636.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2960)
  AUTHORS   Sandhu,J., Li,S., Fairall,L., Pfisterer,S.G., Gurnett,J.E.,
            Xiao,X., Weston,T.A., Vashi,D., Ferrari,A., Orozco,J.L.,
            Hartman,C.L., Strugatsky,D., Lee,S.D., He,C., Hong,C., Jiang,H.,
            Bentolila,L.A., Gatta,A.T., Levine,T.P., Ferng,A., Lee,R.,
            Ford,D.A., Young,S.G., Ikonen,E., Schwabe,J.W.R. and Tontonoz,P.
  TITLE     Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER
            Cholesterol Transport in Mammalian Cells
  JOURNAL   Cell 175 (2), 514-529 (2018)
   PUBMED   30220461
REFERENCE   2  (bases 1 to 2960)
  AUTHORS   Besprozvannaya,M., Dickson,E., Li,H., Ginburg,K.S., Bers,D.M.,
            Auwerx,J. and Nunnari,J.
  TITLE     GRAM domain proteins specialize functionally distinct ER-PM contact
            sites in human cells
  JOURNAL   Elife 7, e31019 (2018)
   PUBMED   29469807
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2960)
  AUTHORS   Feng,Y., Liang,H.L. and Wong-Riley,M.
  TITLE     Differential gene expressions in the visual cortex of postnatal day
            1 versus day 21 rats revealed by suppression subtractive
            hybridization
  JOURNAL   Gene 329, 93-101 (2004)
   PUBMED   15033532
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 12, 2022 this sequence version replaced XM_006228833.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               JAXUCZ010000001.1  95520585-95520716   c
            133-421             JAXUCZ010000001.1  95519632-95519920   c
            422-638             JAXUCZ010000001.1  95508373-95508589   c
            639-659             JAXUCZ010000001.1  95508262-95508282   c
            660-744             JAXUCZ010000001.1  95507534-95507618   c
            745-848             JAXUCZ010000001.1  95507288-95507391   c
            849-944             JAXUCZ010000001.1  95507106-95507201   c
            945-1025            JAXUCZ010000001.1  95505933-95506013   c
            1026-1138           JAXUCZ010000001.1  95504611-95504723   c
            1139-1289           JAXUCZ010000001.1  95504248-95504398   c
            1290-1491           JAXUCZ010000001.1  95503607-95503808   c
            1492-1635           JAXUCZ010000001.1  95502910-95503053   c
            1636-1754           JAXUCZ010000001.1  95500790-95500908   c
            1755-1897           JAXUCZ010000001.1  95500564-95500706   c
            1898-2001           JAXUCZ010000001.1  95499256-95499359   c
            2002-2175           JAXUCZ010000001.1  95498997-95499170   c
            2176-2263           JAXUCZ010000001.1  95498829-95498916   c
            2264-2371           JAXUCZ010000001.1  95497578-95497685   c
            2372-2492           JAXUCZ010000001.1  95497372-95497492   c
            2493-2960           JAXUCZ010000001.1  95494378-95494845   c
FEATURES             Location/Qualifiers
     source          1..2960
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2960
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /note="GRAM domain containing 1A"
                     /db_xref="GeneID:361550"
                     /db_xref="RGD:1311022"
     exon            1..132
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            133..421
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..2585
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /note="isoform 1 is encoded by transcript variant 1; GRAM
                     domain-containing protein 1A; protein Aster-A"
                     /codon_start=1
                     /product="protein Aster-A isoform 1"
                     /protein_id="NP_001386565.1"
                     /db_xref="GeneID:361550"
                     /db_xref="RGD:1311022"
                     /translation="MADLLPLLPWAPQGAQGANQDSSGSPTEQQTQDDNVQDLSPKSW
                     RLLGVPAIHITPSSDGESPPGTPNTPRFQSLKTPDPECLSQDSTTPHSGRSSPSSSPS
                     LRKRLQLLPPSRPPSAPEPEPGTMVEKGSDSSSEKSGVSGTLSTQSLGSRNFIRNSKK
                     MQSWYSMLCPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWIC
                     FYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLL
                     IFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKEVGDV
                     IALSDISPSGAADRSQEPSPVGSRCGRVTPNLSRASSDADHGAEEDKEDQTDSQLDAS
                     SSQTVTPVAEPLSAEPAPPDGPTSNLGPLDLLSREELLTDTSNSSSSTGEEGDLAALL
                     PDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQRKFTDVTLSPWSSDSKCHQRR
                     VLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRY
                     CILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKSSWTGIEDYFHHLDRELAKAEKVS
                     LEEGGKDARGLLSGLRRRKRPLSWRGHRDGPQHPDPDPCTQTSMHTSGSLSSRFSEPS
                     VDQGPGAGIPSALVLISIVLIVLIALNALLFYRLWSLERTAHTFESWHSLALAKGKFP
                     QTATEWAEILALQKHFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVPDPPLDT
                     QPHPDDSFP"
     exon            422..638
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            639..659
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            660..744
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            745..848
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            849..944
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1025
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1138
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1289
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1491
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1492..1635
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1754
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1897
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..2001
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            2002..2175
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            2176..2263
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..2371
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            2372..2492
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
     exon            2493..2960
                     /gene="Gramd1a"
                     /gene_synonym="Eg1rvc; RGD1311022"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcagacta gctgttccgg cctgaaggtc atgagtctcc ggcccagccc aactcaggga
       61 ataaaggaag ggccaggctt tctcttacac tagaagtctg aaccctgtga gacagaagga
      121 agaattcaca aggggccaca ctgctgtcca aattcctcct catggctgac ctgcttcctc
      181 tgctgccctg ggctccccag ggggctcagg gtgctaacca ggactcatct gggtctccaa
      241 ctgagcaaca gacacaggat gacaatgtcc aggacctctc tcctaaatcc tggaggctct
      301 tgggggtgcc tgccattcac ataactccat ccagtgatgg ggaatcacct ccaggcaccc
      361 caaatacacc acgatttcag agtctgaaga ccccggaccc cgagtgtcta tctcaggaca
      421 gcaccacacc ccactctggc cggagctcac cgagcagctc cccgtctctt cggaagcggc
      481 ttcagctctt gcccccaagc cggccgcctt cggctcctga gccagagcca ggcaccatgg
      541 tggagaaggg gtctgacagt tcctctgaga agagcggagt gtccgggaca ctcagcaccc
      601 agagtctggg cagccggaac ttcatccgca acagtaagaa gatgcagagc tggtacagta
      661 tgctgtgtcc cacatacaaa caacgtaacg aggacttccg gaaactcttt agcaaacttc
      721 cagaagcaga acgcctcatt gtggattact cctgcgccct gcagcgggag atcctcctcc
      781 agggccgcct ctacctctct gagaactgga tctgtttcta cagcaacatc ttccgctggg
      841 agaccacgat ttccatccag ttgaaggaag tgacctgtct gaagaaggag aagacggcta
      901 agctcatccc caatgccatt cagatctgta ccgagagtga gaagcatttc ttcacttcct
      961 tcggggcccg agaccgttgc ttcctcctca tcttccgtct ctggcagaac gcgctgctcg
     1021 agaagacact gagtcctcga gagctttggc acctggtcca tcagtgttat ggctcggagc
     1081 tgggcctcac cagtgaagac gaagactatg tctgcccctt gcaactgaat ggactcggga
     1141 gtcccaaaga ggtgggagat gtgattgcac tcagcgacat tagcccctca ggggcagccg
     1201 accgcagcca ggagccaagc cccgtgggtt caaggtgtgg ccgggtcact ccaaacctct
     1261 ctcgagccag cagtgatgca gaccatgggg ccgaggagga caaagaagat cagacggaca
     1321 gtcagctgga tgcctcctcc agccagacag tgaccccagt agcagaacct ctgagtgctg
     1381 agccggcccc gccagatggg cccacgtcca acctgggtcc cctggatctg ctgtccagag
     1441 aggaactgtt gacagacacg agtaactcct cctcatccac tggggaagaa ggtgacctgg
     1501 ctgcattgct gcctgacctc tccggccggc tcctcatcaa ctccgtcttc cacgtgggtg
     1561 ctgaacgtct acagcagatg ctcttctcgg actctccatt cctgcaaggc ttcctgcagc
     1621 agcgcaagtt cacagatgtg accttgagcc cttggagcag tgacagcaag tgccaccagc
     1681 gcagagtcct gacctacacc atccccatta gcaaccagct aggccccaag agcgcctctg
     1741 tggtggagac acagacgctg ttccgacgtg gcccacaggc gggcgggtgc gtggtggact
     1801 ctgaggtgct cacccagggc atcccgtacc aggactactt ctacactgcc caccgatact
     1861 gtatcctggg tctggcccgg aacaaggccc ggcttcgtgt atcctcagag atccgctacc
     1921 gaaagcaacc gtggagcctt gtgaagtctc tcattgagaa gagctcgtgg actggcatcg
     1981 aagattattt ccaccacctg gatcgagaac tggccaaggc agagaaggtg tccctggagg
     2041 aaggggggaa agatgctcgt gggctgctgt caggcctgcg gaggaggaag cgacccctga
     2101 gctggagggg gcacagagat ggacctcagc acccagaccc agacccctgc acccagacca
     2161 gcatgcacac ctcaggttcc ctcagctctc gcttctcgga accatctgtg gatcagggcc
     2221 ccggggcagg catccccagt gccctggttc tcatcagcat tgtcctcatt gttctcatcg
     2281 ccctcaatgc cctcctcttc taccgtctct ggtctctgga gagaacagcc catacctttg
     2341 agtcctggca cagcctggca ctggccaagg gcaagttccc ccagacagcc acggagtggg
     2401 ccgagatctt ggctctgcag aagcatttcc acagcgttga ggtgcacaag tggaggcaga
     2461 tccttcgcgc atccgtggag ctcctggatg agatgaagtt ctccttggag aagctacatc
     2521 aaggaatcac tgtcccagat cctccgctgg acactcagcc acatcccgat gacagttttc
     2581 cctgaggact cctgattgaa aagccactcc cctgaacgga cagaaggaca cacggaaccc
     2641 tggcagccac tgctggcacg gtgtaaacgc cgccgggagg ttcctgcctg cccctcacag
     2701 tggccccgcc aagagccaca cagacctggg gaccatagaa ccaagatgca ctttagatct
     2761 gtgtgtgcct gtaccggtcc agctgccact gcctgctcag ccagggagct ggcctggtct
     2821 ttggcaggct ccccctccaa ctaacttatt ttgcccagct ggggttgtgg gggacacctt
     2881 ttggggtgca cgagaccctc tgggtttaat gtattatatt tatttgggaa tagcaacccc
     2941 aataaagggt tggaaatggc
//
