LOCUS       NM_001003974            1259 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus G-protein signaling modulator 3 (Gpsm3), mRNA.
ACCESSION   NM_001003974
VERSION     NM_001003974.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1259)
  AUTHORS   Giguere,P.M., Billard,M.J., Laroche,G., Buckley,B.K.,
            Timoshchenko,R.G., McGinnis,M.W., Esserman,D., Foreman,O., Liu,P.,
            Siderovski,D.P. and Tarrant,T.K.
  TITLE     G-protein signaling modulator-3, a gene linked to autoimmune
            diseases, regulates monocyte function and its deficiency protects
            from inflammatory arthritis
  JOURNAL   Mol Immunol 54 (2), 193-198 (2013)
   PUBMED   23280397
REFERENCE   2  (bases 1 to 1259)
  AUTHORS   Cao,X., Cismowski,M.J., Sato,M., Blumer,J.B. and Lanier,S.M.
  TITLE     Identification and characterization of AGS4: a protein containing
            three G-protein regulatory motifs that regulate the activation
            state of Gialpha
  JOURNAL   J Biol Chem 279 (26), 27567-27574 (2004)
   PUBMED   15096500
REFERENCE   3  (bases 1 to 1259)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC088220.1.
            
            On Jan 2, 2005 this sequence version replaced NM_001003974.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088220.1, CO570164.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680432, SAMN06680437
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1259
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1259
                     /gene="Gpsm3"
                     /gene_synonym="AGS4; G18; Ng1"
                     /note="G-protein signaling modulator 3"
                     /db_xref="GeneID:406163"
                     /db_xref="RGD:1303014"
     exon            1..346
                     /gene="Gpsm3"
                     /gene_synonym="AGS4; G18; Ng1"
                     /inference="alignment:Splign:2.1.0"
     CDS             311..787
                     /gene="Gpsm3"
                     /gene_synonym="AGS4; G18; Ng1"
                     /note="G-protein signalling modulator 3 (AGS3-like, C.
                     elegans); activator of G-protein signalling 4; G-protein
                     signaling modulator 3 (AGS3-like, C. elegans)"
                     /codon_start=1
                     /product="G-protein-signaling modulator 3"
                     /protein_id="NP_001003974.1"
                     /db_xref="GeneID:406163"
                     /db_xref="RGD:1303014"
                     /translation="MEAERPQEDGEQSLPQDDQGWPPVNSTARPWRSAPPSPPPPGTR
                     HTALGPRSGSLLSLQTELLLDLVAEAQSRRLEEQRAAFHTPKVPPSLAPTPPRLLEDK
                     EQLYSTILSHQCQRIEAQRSDPPLPPGGQELLELLLRVQGGGRMEDQRSRPPTHTC"
     exon            347..449
                     /gene="Gpsm3"
                     /gene_synonym="AGS4; G18; Ng1"
                     /inference="alignment:Splign:2.1.0"
     exon            450..649
                     /gene="Gpsm3"
                     /gene_synonym="AGS4; G18; Ng1"
                     /inference="alignment:Splign:2.1.0"
     exon            650..1228
                     /gene="Gpsm3"
                     /gene_synonym="AGS4; G18; Ng1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccgcccgtc aggagcacac tccactcctg cagctggaat ttctcccagt ctctgtcctc
       61 ccctggggca agagaggtca agcgagctgt ttgggtggga aaaagcgagg atggaggaag
      121 ttgacagaga tgggcggggc ccgtgggggg gctgaccaac aacccagctt cctgctcagt
      181 acctaggcat ccagccccca gctcaccccc accccttcca gaccccattc ccctcaggaa
      241 cccaaggttc cagtcctcct cccaaattcc agccacccct ccccatcagt gtctctcccc
      301 aagtccaggg atggaggctg aaagacccca ggaagatggt gagcagagtc tccctcagga
      361 tgatcagggc tggccccctg tgaactccac cgctcggcct tggagatctg cacctccctc
      421 ccctcctcct cctggaaccc gacacacagc cctggggccc cgttctggct ccctgctctc
      481 cctgcagact gagctccttc tggacctggt ggctgaagcc cagtcacgcc gtctagagga
      541 acagagggcc gccttccaca cccccaaggt tcccccaagc ctagccccaa ccccaccccg
      601 gcttcttgaa gacaaagaac agctctacag caccatactc agtcaccagt gccagcggat
      661 tgaagcccaa cggtccgacc cgccccttcc ccccggcggg caggagctcc tggagttgct
      721 gctcagagtt cagggtggag gtcgaatgga ggaccaaaga tctcggcccc ctacacacac
      781 ctgctgaggc ctgagctccc aaccagtccc ttctctctgg gactcaaagc tgggacactc
      841 cccgaaggtc ttcaaccctg tttggctggg gtaccagaga ctgaagaccc ggctaaaatt
      901 gcacccactt tccctgggga ctggacttga gacaagtact ctaaccttga agataagtaa
      961 ggtagggttg gacacagctc cctgaggcag ttaagagtct ctctcctgag ctgtcaagct
     1021 actaaacagg ttgtgagggc tgaggcctgt ccctgcctag tgagaaaaaa gggaaaagag
     1081 taagacgact gtccagcgct agcacccccc acgcccgacc ccaaggcaga ggggcgcaga
     1141 ggctgtgaag cgaccttagc accgccccca ccctactgcc gagtctgtct gatgttttgg
     1201 ttgtacgaat aaatataatt cccctctgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
