LOCUS       NP_001387629             914 aa            linear   ROD 30-MAR-2024
DEFINITION  G protein-regulated inducer of neurite outgrowth 1 [Rattus
            norvegicus].
ACCESSION   NP_001387629 XP_344572
VERSION     NP_001387629.1
DBSOURCE    REFSEQ: accession NM_001400700.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 914)
  AUTHORS   Nordman,J.C., Phillips,W.S., Kodama,N., Clark,S.G., Del Negro,C.A.
            and Kabbani,N.
  TITLE     Axon targeting of the alpha 7 nicotinic receptor in developing
            hippocampal neurons by Gprin1 regulates growth
  JOURNAL   J Neurochem 129 (4), 649-662 (2014)
   PUBMED   24350810
  REMARK    GeneRIF: alpha7 activation reduces hippocampal axon growth by
            coupling to Gprin1, which targets it to the growth cone. An
            alpha7/Gprin1 interaction is linked to a Galphao, growth-associated
            protein 43, and CDC42 cytoskeletal regulatory pathway within the
            developing axon.
REFERENCE   2  (residues 1 to 914)
  AUTHORS   Chen,L.T., Gilman,A.G. and Kozasa,T.
  TITLE     A candidate target for G protein action in brain
  JOURNAL   J Biol Chem 274 (38), 26931-26938 (1999)
   PUBMED   10480904
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Jan 26, 2022 this sequence version replaced XP_344572.7.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.68472.1,
                                           SRR26360194.1069587.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..914
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     Protein         1..914
                     /product="G protein-regulated inducer of neurite outgrowth
                     1"
                     /calculated_mol_wt=93293
     Region          <472..>709
                     /region_name="PRK07003"
                     /note="DNA polymerase III subunit gamma/tau"
                     /db_xref="CDD:235906"
     Region          775..911
                     /region_name="GRIN_C"
                     /note="G protein-regulated inducer of neurite outgrowth
                     C-terminus; pfam15235"
                     /db_xref="CDD:464577"
     CDS             1..914
                     /gene="Gprin1"
                     /coded_by="NM_001400700.1:258..3002"
                     /db_xref="GeneID:364676"
                     /db_xref="RGD:1308762"
ORIGIN      
        1 mrdrcsspka ipapprhild qslgmdsrhs sssgagegas caekpvgsla csplpetvra
       61 hgaltsease ttlfgkpepm ssveapsaae vrnpsssekm dsnslkqeds tssrkegags
      121 lrkeesmlvg kteplicgkg asetgvrvec sapkkeesgs lgtvdtacss kvdivppgge
      181 nagslrkvet iasgkmdprk enlmysrrey pestgegdlv sprgndmkpp dkadpgfsge
      241 lppgssgktk hvssvavapv tsenvnpass gitdpvasgd tetlssgkgd prflgkkepv
      301 stgesgpvsv rmaepvsagq pegmvpakkd ptsanstgps grvdsvslrn selvspvkpe
      361 hlssgqaerv slvktetlfs gkedprssgr vettvtgnik tfqkgnpess gktdpvssfs
      421 sgdagslgtl gslsaaktet vtegkgdpqs lekasptase kadplalcke ssasqgkaet
      481 vpsgevgstt lgktastssg ktalvspgkv dltaseraeg vpelrapekg npgnstrvdt
      541 tepksgvkvv tqlpgatspg kveapslqke qpqpsektdp sgkvdptasv epvslgkads
      601 astspsprka esqtsaktvp qapdkatsaf rqsdgtpyss aqprrdtrsi galpepepsa
      661 stsqkdlaav aaqkspsaeg aapppgprtr dnftkapswd agapppreda gtqagaqacv
      721 svavspmspq dgavgpafsf qaatrapspa prppsrrdag lqvslgaaet rsvatgpmtp
      781 qaaappaapp vfpevrvrpg svlaaamapq eaaepvrdvs wdekgmtwev ygasmevevl
      841 gmaiqkhler qieehgrqga papppavrag pgragsvrta paegaakrpp glfrallqsv
      901 rrprccsrag ptae
//
