LOCUS       NM_001271106            3033 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor, class C, group 6,
            member A (Gprc6a), mRNA.
ACCESSION   NM_001271106 XM_228164
VERSION     NM_001271106.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3033)
  AUTHORS   Jacobsen,S.E., Ammendrup-Johnsen,I., Jansen,A.M., Gether,U.,
            Madsen,K.L. and Brauner-Osborne,H.
  TITLE     The GPRC6A receptor displays constitutive internalization and
            sorting to the slow recycling pathway
  JOURNAL   J Biol Chem 292 (17), 6910-6926 (2017)
   PUBMED   28280242
  REMARK    GeneRIF: GPRC6A predominantly undergoes constitutive
            internalization with the early endosome marker Rab5 and the long
            loop recycling endosome marker Rab11 and to a much lesser extent
            with the late endosome marker Rab7
REFERENCE   2  (bases 1 to 3033)
  AUTHORS   Wellendorph,P., Burhenne,N., Christiansen,B., Walter,B., Schmale,H.
            and Brauner-Osborne,H.
  TITLE     The rat GPRC6A: cloning and characterization
  JOURNAL   Gene 396 (2), 257-267 (2007)
   PUBMED   17478059
  REMARK    GeneRIF: cloning and characterization of rat GPRC6A
REFERENCE   3  (bases 1 to 3033)
  AUTHORS   Pi,M., Faber,P., Ekema,G., Jackson,P.D., Ting,A., Wang,N.,
            Fontilla-Poole,M., Mays,R.W., Brunden,K.R., Harrington,J.J. and
            Quarles,L.D.
  TITLE     Identification of a novel extracellular cation-sensing
            G-protein-coupled receptor
  JOURNAL   J Biol Chem 280 (48), 40201-40209 (2005)
   PUBMED   16199532
REFERENCE   4  (bases 1 to 3033)
  AUTHORS   Wellendorph,P. and Brauner-Osborne,H.
  TITLE     Molecular cloning, expression, and sequence analysis of GPRC6A, a
            novel family C G-protein-coupled receptor
  JOURNAL   Gene 335, 37-46 (2004)
   PUBMED   15194188
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Aug 31, 2012 this sequence version replaced XM_228164.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ535460.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-218               JAXUCZ010000020.1  31485904-31486121   c
            219-522             JAXUCZ010000020.1  31476551-31476854   c
            523-1359            JAXUCZ010000020.1  31475288-31476124   c
            1360-1572           JAXUCZ010000020.1  31471218-31471430   c
            1573-1696           JAXUCZ010000020.1  31466714-31466837   c
            1697-3033           JAXUCZ010000020.1  31464818-31466154   c
FEATURES             Location/Qualifiers
     source          1..3033
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..3033
                     /gene="Gprc6a"
                     /note="G protein-coupled receptor, class C, group 6,
                     member A"
                     /db_xref="GeneID:294394"
                     /db_xref="RGD:735077"
     exon            1..218
                     /gene="Gprc6a"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..2811
                     /gene="Gprc6a"
                     /note="G-protein coupled receptor family C group 6 member
                     A"
                     /codon_start=1
                     /product="G-protein coupled receptor family C group 6
                     member A precursor"
                     /protein_id="NP_001258035.1"
                     /db_xref="GeneID:294394"
                     /db_xref="RGD:735077"
                     /translation="MALSFVFITCFMILLDTSQSCHTPDDFVAITSPGHIMIGGLFAI
                     HEKMLSSDDHPRQPQIQKCVGFEISVFLQTLAMIHSIEMINNSSLLSGVKLGYEIYDT
                     CTEVTAAMAATLRFLSKFNCSRETVIFQCDYSSYVPRVKAIIGAGYSEISMAVSRMLN
                     LQLMPQVSYESTAEILSDKIRFPSFLRTVPSDFYQTKAMAHLIRQSGWNWVGAITTDD
                     DYGRLALNTFAIQAAENNVCIAFKEVLPAFLSDNTIEVRINQTLEKIIAEAQVNVIVV
                     FLRKFHVFNLFNKAIERKISKIWIASDNWSTAAKIITIPNVKKLGKVVGFTFRRGNMS
                     SFHSFLQTLHMYPSDNNKPLHEFAMLFSACKHIKDGDLSQCISNYSQATWTYDTTKTI
                     ETHLFKRNDFLWHYTEPGLIHSIQLAVLALGHAIRDLCQDRDCQKPNAFQPWELLAVL
                     KNVTFTDGKNSFHFDAHGDLNTGYEVVLWKETNGLMTVTKMAEYDLQHDVFITTNQET
                     KHEFRKLKQILSKCSKECIPGQMKKATGSQHSCCYECVNCPENHYSNETDMDHCLVCN
                     NETHWAPVRSTMCFEKEVEYLDWDDSLALLLIALSLLGIAFVLAVGIIFTRNLKTPVV
                     KSSGGLVVCYVMLACHALNFASTGFFIGEPQDFTCKTRQTLFGVSFTLCVSCILTKSL
                     KILLAFSFDPTLKTFLKCLYRPVPIVLTCTGIQVVICTLWLVLAAPTVEENTSLPRVI
                     ILECEEGSALAFGTMLGYIAVLAFICFVFAFKGRKLPENYNEAKFLTFGMLIYFIAWI
                     TFIPVYATTFGKYLPAVEIIVILISNYGILCCTFFPKCYIILCKQKTNTKSVFLQMVY
                     NYSAHSVDSLALSHVSLDSASHSTATTNPRPGNKTAACQNYKHLPVQVLAHTGMEKTM
                     HASKTLHQKRSSSI"
     exon            219..522
                     /gene="Gprc6a"
                     /inference="alignment:Splign:2.1.0"
     exon            523..1359
                     /gene="Gprc6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1572
                     /gene="Gprc6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1696
                     /gene="Gprc6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..3033
                     /gene="Gprc6a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catgaactga gcaaatgaga cagcatggcc ctatcatttg tatttattac ttgcttcatg
       61 attcttcttg atacctccca gtcttgtcat accccagatg acttcgtggc tatcacttct
      121 cctggacata tcatgattgg tggtttgttt gccattcacg aaaaaatgtt gtcctcagat
      181 gaccatccca ggcaaccaca aatccagaag tgtgttggtt ttgaaatatc agtgtttctt
      241 caaactctgg ctatgataca cagcattgag atgatcaata actcaagcct gttgtccgga
      301 gttaagctgg ggtatgaaat ctatgacact tgtactgaag tcacagcggc aatggctgcc
      361 accctgaggt tcctctctaa attcaactgc tctagagaaa ccgtgatctt tcaatgtgac
      421 tattccagct acgtgccaag ggtcaaggcc atcataggtg ctggctactc tgaaatatcc
      481 atggcggtct cgaggatgct gaatttacag ctcatgccac aggtgagtta tgaatccact
      541 gcagaaatcc tgagtgacaa aatccgcttt ccttcgtttt tacgaaccgt gcccagtgac
      601 ttctaccaaa ctaaagcaat ggcccacctg atccgacaat ccggatggaa ctgggttggt
      661 gccataacaa ccgacgatga ttatggaaga ctagcgctca acacatttgc aatccaggct
      721 gctgaaaaca atgtgtgcat cgccttcaaa gaggttctgc cagccttcct ctcagataat
      781 accattgaag tgagaatcaa ccagactctg gagaaaatca ttgccgaagc ccaggtcaat
      841 gtcatcgtgg tgtttcttag gaaattccac gtcttcaatc tcttcaacaa agccatcgag
      901 aggaaaataa gtaagatctg gattgctagt gataactggt caactgctgc caagattatc
      961 accattccca atgttaagaa gcttggcaaa gtagtgggct ttacttttag gagaggaaat
     1021 atgtcttctt tccattcttt tcttcaaact ctgcatatgt accccagtga caataacaaa
     1081 cccctacatg agtttgccat gcttttttct gcctgtaaac acatcaaaga tggtgatttg
     1141 agccaatgca tttccaacta ttctcaggca acttggacct atgacactac caagaccatt
     1201 gagacccatt tattcaagag aaatgacttc ctttggcatt atactgagcc aggactcatt
     1261 cacagcattc agcttgctgt gcttgccttg ggccatgcca tccgggatct gtgccaagat
     1321 cgagactgcc agaaacccaa cgcctttcag ccatgggagc tacttgcggt gctgaaaaac
     1381 gtgacattca ctgacggaaa aaactcattt cattttgatg cccatgggga tttaaatact
     1441 ggttacgagg tggtgctctg gaaagagact aacggcctca tgactgtcac gaagatggca
     1501 gaatatgacc tgcagcatga cgtcttcatc accacaaacc aagaaacaaa gcatgaattc
     1561 aggaaactta agcaaattct atctaaatgc tccaaagaat gcattcctgg tcaaatgaag
     1621 aaagccacag gaagccaaca cagctgttgc tatgaatgtg tgaactgccc agaaaaccac
     1681 tacagtaatg agacagacat ggatcactgc ctcgtatgca acaacgaaac ccactgggcc
     1741 ccagtaagga gcacgatgtg cttcgagaag gaagtggagt atcttgactg ggatgactcc
     1801 ttggctctcc tcctcattgc cctctcccta cttggaattg cctttgttct ggccgttggc
     1861 ataatattta caagaaacct gaagacacct gtggtgaaat catctggggg attagtggtc
     1921 tgttacgtga tgctcgcctg ccatgccctc aactttgcca gcacaggctt ttttattgga
     1981 gaaccacagg acttcacgtg caagaccagg cagaccctgt ttggcgtgag ctttactctg
     2041 tgtgtctcct gtattttgac gaagtccctg aaaattttgc tagccttcag cttcgacccc
     2101 acgctgaaga cattcctgaa gtgtctctat aggccagtcc ccattgtcct tacctgcacg
     2161 ggcattcaag tggtcatttg cacgctttgg ctggtcctgg cagcacctac tgtggaagag
     2221 aacacctcct tgcctagagt cattatccta gaatgtgagg agggatctgc actggcgttt
     2281 ggcaccatgc tgggctacat tgcagttctg gccttcattt gttttgtatt tgcattcaag
     2341 gggaggaagc ttcctgagaa ttacaacgaa gctaagttcc tgacctttgg gatgctgatt
     2401 tacttcatag cttggatcac attcatccca gtctatgcta ccactttcgg caagtatttg
     2461 cccgctgtgg agatcatagt cattctgata tccaactatg gtatcctctg ctgtacattc
     2521 ttccccaagt gctacattat tctttgcaag caaaagacta acactaagtc agtcttcctc
     2581 cagatggttt acaattactc tgctcacagc gtggacagcc ttgccttgag tcacgtatcc
     2641 ctggactccg ccagccacag tactgcaaca accaacccga ggcctggtaa caagactgca
     2701 gcctgtcaga attacaaaca tcttcctgta caagtgcttg ctcacacagg catggaaaag
     2761 actatgcacg cgtctaaaac tttgcatcag aaaagaagtt caagtatatg actgagttct
     2821 caggagaggc tatgattccc caataagatg tttctggtga tggctgcaaa ttgtgtattt
     2881 atttttctta gcaaatacat cttgggtttt tgttgtttgt ttggtttctg tttttcttct
     2941 ttgctttttg gggttcttct ttctaccact ttcttgaaca ctctgttcaa ctcattctgt
     3001 ttaacaatct gctaataaaa aatagtttcc ata
//
