LOCUS       NM_134386               5361 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor associated sorting
            protein 1 (Gprasp1), mRNA.
ACCESSION   NM_134386 XM_017601903
VERSION     NM_134386.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5361)
  AUTHORS   He,C., Wei,Y., Sun,K., Li,B., Dong,X., Zou,Z., Liu,Y., Kinch,L.N.,
            Khan,S., Sinha,S., Xavier,R.J., Grishin,N.V., Xiao,G.,
            Eskelinen,E.L., Scherer,P.E., Whistler,J.L. and Levine,B.
  TITLE     Beclin 2 functions in autophagy, degradation of G protein-coupled
            receptors, and metabolism
  JOURNAL   Cell 154 (5), 1085-1099 (2013)
   PUBMED   23954414
REFERENCE   2  (bases 1 to 5361)
  AUTHORS   Kiyama,A., Isojima,Y. and Nagai,K.
  TITLE     Role of Per1-interacting protein of the suprachiasmatic nucleus in
            NGF mediated neuronal survival
  JOURNAL   Biochem Biophys Res Commun 339 (2), 514-519 (2006)
   PUBMED   16298334
  REMARK    GeneRIF: nuclear translocation of PIPS is involved in NGF mediated
            neuronal survival via TrkA, PI3K, and Gab1 signaling pathway
REFERENCE   3  (bases 1 to 5361)
  AUTHORS   Bartlett,S.E., Enquist,J., Hopf,F.W., Lee,J.H., Gladher,F.,
            Kharazia,V., Waldhoer,M., Mailliard,W.S., Armstrong,R., Bonci,A.
            and Whistler,J.L.
  TITLE     Dopamine responsiveness is regulated by targeted sorting of D2
            receptors
  JOURNAL   Proc Natl Acad Sci U S A 102 (32), 11521-11526 (2005)
   PUBMED   16049099
REFERENCE   4  (bases 1 to 5361)
  AUTHORS   Tischkau,S.A., Mitchell,J.W., Tyan,S.H., Buchanan,G.F. and
            Gillette,M.U.
  TITLE     Ca2+/cAMP response element-binding protein (CREB)-dependent
            activation of Per1 is required for light-induced signaling in the
            suprachiasmatic nucleus circadian clock
  JOURNAL   J Biol Chem 278 (2), 718-723 (2003)
   PUBMED   12409294
  REMARK    GeneRIF: Ca(2+)/cAMP response element-binding protein (CREB) and
            Per1 are integral components of the pathway transducing
            light-stimulated GLU neurotransmission into phase advance of the
            circadian clock
REFERENCE   5  (bases 1 to 5361)
  AUTHORS   Sumova,A., Sladek,M., Jac,M. and Illnerova,H.
  TITLE     The circadian rhythm of Per1 gene product in the rat
            suprachiasmatic nucleus and its modulation by seasonal changes in
            daylength
  JOURNAL   Brain Res 947 (2), 260-270 (2002)
   PUBMED   12176169
  REMARK    GeneRIF: Per1 gene product in the rat suprachiasmatic nucleus is
            modulated by seasonal changes in daylength.
REFERENCE   6  (bases 1 to 5361)
  AUTHORS   Matsuki,T., Kiyama,A., Kawabuchi,M., Okada,M. and Nagai,K.
  TITLE     A novel protein interacts with a clock-related protein, rPer1
  JOURNAL   Brain Res 916 (1-2), 1-10 (2001)
   PUBMED   11597585
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On or before Mar 8, 2021 this sequence version replaced
            XM_017601903.2, NM_134386.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.528611.1,
                                           SRR26643429.59498.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               JAXUCZ010000021.1  103556493-103556707
            216-278             JAXUCZ010000021.1  103557921-103557983
            279-354             JAXUCZ010000021.1  103558144-103558219
            355-426             JAXUCZ010000021.1  103558366-103558437
            427-503             JAXUCZ010000021.1  103558599-103558675
            504-574             JAXUCZ010000021.1  103558833-103558903
            575-656             JAXUCZ010000021.1  103559220-103559301
            657-5361            JAXUCZ010000021.1  103559571-103564275
FEATURES             Location/Qualifiers
     source          1..5361
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq32"
     gene            1..5361
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /note="G protein-coupled receptor associated sorting
                     protein 1"
                     /db_xref="GeneID:171407"
                     /db_xref="RGD:621343"
     exon            1..215
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            216..278
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            279..354
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            355..426
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            427..503
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            504..574
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            575..656
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     exon            657..5361
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /inference="alignment:Splign:2.1.0"
     CDS             966..5006
                     /gene="Gprasp1"
                     /gene_synonym="pips"
                     /note="GASP-1; per1-interacting protein; Per1 interacting
                     protein"
                     /codon_start=1
                     /product="G-protein coupled receptor-associated sorting
                     protein 1"
                     /protein_id="NP_599213.2"
                     /db_xref="GeneID:171407"
                     /db_xref="RGD:621343"
                     /translation="MTGAEVEPGAQAKAENKPGDENANAAEVEPEVPLVVRPKVRTQM
                     MTGARPKVKPKGTPGARPKGETSSPGGAYAKCKPRSIPISRSKHDAQVWAPSKFRGES
                     MSKMGKQCQISAADSPLVSNDSGAVAQAKCLSVDRELANMDTESIPKKASSPARFQPS
                     FGPEEGTSMGSWYRPRPIPKGEAYENSDFKWADKSSGSSSFWNRDETSTRFRPRKSMK
                     SNTRFRHMAKQEANTMSRHKNKQEFYNISSSDSEDESAKTPWFWAKDKPKVWSRPKEE
                     PNTRSWFRSKKEVRVESTSGSECENHTKSLFWSGEEAKCRSKPRARKGVNMRARHQAK
                     REAYSDVTSGSVDKNKKDSWFLPEEKANAFSKSKTKKEPRTRAMPREEVKTKARASTK
                     QEARPEEEVLVGAWFWNTQDNTMGERISMKTTCVEEEPIVGDWFWSEEEASVDSETGL
                     KSRPRAKEEQVSSFCLGSGKKTSMESGPKATSKSMPVAKDDEVIIGSWFWADDEEISL
                     QADDESIFGSWFWGTGEKSLRSVGVSCEKMPKSGEKEVTDSWFWAGEVNTEAEMEEQA
                     SSASTKGTIFVPWFWSEKQAHMDLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEV
                     NSKSSLEDEEEPIRSPWFGAREQPNMKYAAGVGYKPMAEAEEANKKSCVWAKEPCLYP
                     TNRESLKSTLGEKEDTVDPWLWSNNYPRTETITGSWLWAAEEGNIDDETGEEIKLPTL
                     EDNVFNSWFWKENEETVVEAPNREESKPEAEEEDIIGSWFWAGDEDRFQPAAKIKEEN
                     KIAPEDEDTVGSWFWGKEEASVEAVKGGTFESVSGIKEEKATGSWFWTDKAKIGAGPQ
                     TVETGSETEDEAIFESLIWAAKKDSMQTGVNRVSKPKDEGEGIESWLWSGDKATTESK
                     TVTVSESSPENGKESIVKFGSRAKDEVINKTGSGDNCKFSTEAESIVGPWFWEGDEAS
                     FESNPVPVCKAACEPESSTEHEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSLNPFRFP
                     KEAASLFAEMFGGKPKLVEVGTEREPEPQFPFQYDPSYRSVREIREHLKARESAQAEN
                     WSCNCIQCELRIGSEEFEELLLMMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGV
                     ISLIEALMNYPSSRARTAFLENMIQMAPTYPDLNMIETYVCQVCEDTFDYDLDSSDQL
                     SGLTMITHLTTTFDYHKVVVAYLAGFYYLLNSGNTTTRFHVLKLLLNLSESLVMTKRL
                     LITDSVSEFMALFNREDSDENIQIILAIFENISKNIQKEALFADDEEEEEEEEAVNLE
                     PLISAFREAEKFAKELKRKTDDQKSP"
ORIGIN      
        1 cttcccgaca ccctccagga gagctgtgct tgccgcagtc tgcgcagccc ctgcccgttt
       61 ggtgcagagg cgtgggggca ggacacagct ctgccattcc actcgcgctc aaagcagtga
      121 aagcccagtg aaaggatctg cggaggacag agaacagccg ggagcaggag agggacgcgg
      181 gggagcccgg ggacctgggc tgtgcccctg gccagccctg ctttaaggct gcaagcaagg
      241 aaagaaggct tctaggcgac tgtctcagat ctctggaggt ctgctttaag gctggttttt
      301 ctgcaatcaa ggaaagaagg tttcaaggcg actgtctcag atctctggaa gttggtctgc
      361 tttaaggctg gtcagttctt caatcaagaa aaaaaggctt cagggtgact gtctcagatc
      421 ttggaggtct gctttaaggc tggtcagttc ttcaatcaag gaaagaaggt ttcaaggcaa
      481 ctgtctcaga tctctggaag ttggtctgcc ctaaggctgg tttttctgca agcaaggaaa
      541 gaaggcttca gggcgactgt ctcagatctt ggaggactcc ctgcagtcag ccagctgttt
      601 gtcttaacac tgcttgaaca cagaagagag gggagaactg caccacatct gtgaagatca
      661 cctgcagtgg ccgcttggtg gtgctgaggt tgccgctgac cagtgcaatc aacaggtctg
      721 cacccaccta ggacctgttc gtcgtcctcc agcttgattt cacctcttct gcactgtatc
      781 tgtgttattg actgagactg cttgggtagg agcctccttg agtgctgaac tgttcatttc
      841 agtctaattc ttttcaatct cataccaagt taccaaaggt ggtagtgaag agctatcttg
      901 taacagatat ctagtgaagg ttcactgtta agtgctatac attggggctt catctaccgt
      961 atactatgac tggggcagag gttgagcctg gtgcccaggc aaaggctgaa aataagcctg
     1021 gggatgagaa tgctaatgct gctgaagtag agcctgaagt tccgttagtg gtcagaccca
     1081 aggttaggac acaaatgatg actggagcaa gacccaaagt gaagcctaag ggtacccctg
     1141 gagcaaggcc taaaggtgaa accagttcac caggtggggc atatgctaaa tgtaagccca
     1201 ggtcaatccc tatttcacga tctaagcatg atgcacaagt ctgggccccg agtaagtttc
     1261 gtggtgagtc catgtcaaag atggggaagc aatgtcagat cagtgctgca gactccccac
     1321 tggtcagtaa tgattctggg gcggttgctc aagctaagtg cctgtctgta gatagagaac
     1381 ttgctaatat ggacactgag agtattccca aaaaggccag ttctccagca agattccagc
     1441 cttcatttgg cccagaggag ggaaccagta tgggatcctg gtaccgtccc aggcctatcc
     1501 ctaaaggaga ggcatatgag aattctgatt tcaaatgggc agataaatcc tcaggaagtt
     1561 cctccttctg gaatagagat gaaaccagta caagatttcg tcctaggaaa agcatgaaat
     1621 ccaataccag attcaggcac atggccaaac aagaggcaaa taccatgtct agacacaaga
     1681 acaaacagga gttctataat atttccagtt ctgattctga agatgagtct gctaagactc
     1741 cctggttctg ggccaaagac aagcccaaag tctggtctag gcccaaagaa gagcccaata
     1801 ctaggtcctg gtttaggtct aagaaagaag tccgtgttga atccacttct gggtctgaat
     1861 gtgaaaacca tacaaaatct ttgttttggt ctggagaaga ggctaaatgt aggtctaaac
     1921 ccagagccag gaaaggggtc aatatgaggg ccaggcacca ggccaagcga gaagcttata
     1981 gtgatgtcac atctggatct gtagataaaa ataagaaaga ttcctggttc ttgcctgaag
     2041 agaaagctaa tgccttttca aagtctaaga caaagaaaga gcccagaacc agagcaatgc
     2101 caagggaaga agtcaaaact aaggccagag caagtaccaa acaagaagcc aggccagagg
     2161 aggaagtcct cgttggggct tggttctgga acacccagga caacactatg ggggagagga
     2221 taagcatgaa gaccacttgt gtagaggagg agcctattgt tggagattgg ttctggagtg
     2281 aagaagaagc cagtgtggac tctgagaccg gtcttaaatc cagaccaagg gctaaggagg
     2341 aacaagttag tagtttctgt ttaggatctg gaaagaagac cagtatggaa agtgggccaa
     2401 aggctacttc taaatctatg ccagtagcta aggatgatga ggtcattatt ggatcctggt
     2461 tctgggctga tgatgaagag atcagcttac aggctgatga tgagtctatt tttggatctt
     2521 ggttctgggg cactggtgag aaaagcctta gatctgttgg agtcagttgt gagaagatgc
     2581 ccaagtctgg ggaaaaagaa gttactgatt cctggttctg ggctggagaa gtcaatactg
     2641 aggctgagat ggaggaacag gccagttcag catccacaaa aggaacaatc tttgtgcctt
     2701 ggttttggtc tgaaaagcaa gcacatatgg atttaggaac cgaaccttgc tctgacatca
     2761 tggcaggagc tgaggaggag cccataattg ggccctggtt ctgggctaaa gtagataata
     2821 gtgtggaggc tgaagttaat agtaagtcta gccttgaaga tgaggaagaa cccattagat
     2881 caccttggtt tggggccaga gaacaaccca atatgaagta tgcagctggt gtcggataca
     2941 agcctatggc agaagccgag gaggctaaca aaaagtcgtg tgtctgggca aaagagccct
     3001 gtttgtatcc taccaataga gaaagcttga aatctactct gggagagaaa gaggacactg
     3061 ttgatccatg gctctggtcc aataattacc caaggaccga gaccatcaca gggtcctggc
     3121 tctgggctgc agaagaggga aatatagatg atgagactgg agaagaaatc aaactaccaa
     3181 ctttagagga caatgtattc aattcttggt tctggaaaga aaatgaagaa accgttgtag
     3241 aggctcccaa cagagaagag tccaagccag aagcggaaga ggaagatatt attggctctt
     3301 ggttttgggc tggggatgaa gacaggtttc agccagctgc taagattaag gaagagaaca
     3361 agatagcacc tgaagatgaa gatacagttg gatcctggtt ctggggcaag gaagaggcca
     3421 gtgtagaggc agtgaaaggg ggtacttttg agtctgtgtc tggaattaag gaagagaaag
     3481 ctactgggtc gtggttctgg actgataagg ccaaaatagg ggctgggcca cagactgtcg
     3541 aaactgggtc agaaactgaa gatgaggcaa tttttgagtc cctgatctgg gccgcaaaaa
     3601 aggacagtat gcaaacagga gtaaaccgtg tgtccaagcc aaaggatgag ggtgaaggga
     3661 ttgagtcctg gctctggtct ggtgacaagg ccactacaga atctaaaact gtgacggtca
     3721 gtgagtctag tccagaaaat gggaaagagt ccattgttaa gtttgggtca agagcaaagg
     3781 atgaagtgat taacaagact ggcagcggtg acaattgtaa atttagtaca gaagctgaaa
     3841 gcatagtggg accctggttc tgggaaggag atgaagctag ctttgaatca aaccctgttc
     3901 ctgtatgcaa ggccgcttgt gaacctgagt cttcaactga acatgaacct gatccttccc
     3961 gcaggcctca gagctgggat gaggtcactg ttcagtttaa gcctggtcca tggggaaagg
     4021 ctggcttccc atccttaaac cccttccgat tcccaaaaga agcagcatct ctgtttgcag
     4081 aaatgtttgg gggaaagcct aagcttgtgg aagttggtac tgaaagagag cctgaacccc
     4141 agttcccatt tcagtatgat ccttcttacc ggtcagtccg ggaaattcgg gagcatctta
     4201 aggccaggga gagtgcacag gctgagaact ggtcttgcaa ctgcatccag tgtgagctta
     4261 gaattggttc tgaggagttt gaggaacttc ttttaatgat ggacagaaat cgtgatccat
     4321 ttatccatga gatatctaaa attgcaatgg gcatgagagg tgcttctcag tttacccgag
     4381 atttcattcg aaactcgggt gttatctcac ttattgaagc cctgatgaat tatccttcct
     4441 cccgagcgag gactgccttt ttggaaaaca tgattcaaat ggctccaact tatccagacc
     4501 taaacatgat cgagacatat gtgtgtcagg tgtgtgagga tacctttgat tatgacttgg
     4561 attcctctga ccagttgtct ggactgacaa tgattacaca cctcactact acttttgact
     4621 atcacaaagt ggttgtcgct tacttggctg gcttttacta cctactgaat tcgggcaata
     4681 ccacaacaag gtttcatgtt ctgaaactgc tactaaattt gtctgaaagc cttgtcatga
     4741 caaaacgcct acttattact gattcagtgt cagaatttat ggcccttttt aatagggagg
     4801 actcagatga aaacattcaa attattcttg caatatttga gaatatcagt aaaaatattc
     4861 aaaaagaggc actgtttgct gatgatgagg aagaggagga ggaggaggag gcggtgaatc
     4921 ttgaaccgct tatttcagca ttccgtgagg ctgaaaaatt tgccaaggaa ctgaaacgta
     4981 aaaccgacga tcagaaatca ccctgaagca gaacaaaaag agtaatgtgc ttaaccattt
     5041 gcctccggtt gtccttgtgt tcccaagtca ttgaccctca aataatgctt tgctttccca
     5101 gctgactctg tgtttcactg tgcctcttta tgctggtggt aattataccc aaccctgtgt
     5161 aatctgtatc attattctaa tgccaaatga agatacaagt gaaaacacat gacacttgtt
     5221 ggtgaccctc gtttcgttga ctgtgatgtt cagtatttga gtgtaaagtg aactgagccg
     5281 gtgtaaataa gattcccttc taaatgttgt tctcatgtat atttgagtct tgtgcttcaa
     5341 taaagttcta tgtggacgtg a
//
