LOCUS       NM_001139486            1824 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 89B (Gpr89b), mRNA.
ACCESSION   NM_001139486 XM_001060170 XM_342301
VERSION     NM_001139486.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1824)
  AUTHORS   Tarutani M, Nakajima K, Uchida Y, Takaishi M, Goto-Inoue N, Ikawa
            M, Setou M, Kinoshita T, Elias PM, Sano S and Maeda Y.
  TITLE     GPHR-dependent functions of the Golgi apparatus are essential for
            the formation of lamellar granules and the skin barrier
  JOURNAL   J Invest Dermatol 132 (8), 2019-2025 (2012)
   PUBMED   22572823
REFERENCE   2  (bases 1 to 1824)
  AUTHORS   Maeda Y, Ide T, Koike M, Uchiyama Y and Kinoshita T.
  TITLE     GPHR is a novel anion channel critical for acidification and
            functions of the Golgi apparatus
  JOURNAL   Nat Cell Biol 10 (10), 1135-1145 (2008)
   PUBMED   18794847
REFERENCE   3  (bases 1 to 1824)
  AUTHORS   Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y,
            Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H and Sugano S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY548897.1, DY546285.1, BC166718.1 and CO387870.1.
            
            On or before Nov 19, 2008 this sequence version replaced
            XM_001060170.1, XM_342301.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY724489.1, SRR8487226.158173.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-667               DY548897.1         1-667
            668-1131            DY546285.1         230-693
            1132-1339           BC166718.1         1123-1330
            1340-1775           CO387870.1         21-456              c
            1776-1824           BC166718.1         1767-1815
FEATURES             Location/Qualifiers
     source          1..1824
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1824
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /note="G protein-coupled receptor 89B"
                     /db_xref="GeneID:362003"
                     /db_xref="RGD:1304837"
     exon            1..140
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1466
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /codon_start=1
                     /product="G protein-coupled receptor 89"
                     /protein_id="NP_001132958.1"
                     /db_xref="GeneID:362003"
                     /db_xref="RGD:1304837"
                     /translation="MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEVRQYVVQVIF
                     SVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNI
                     QLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMAL
                     LSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAVTRRTMFQRG
                     DVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIE
                     YSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQF
                     DVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFV
                     SSVLLIRMSMPPEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPE
                     KHMAP"
     exon            141..200
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            201..304
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            305..411
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            412..513
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            514..634
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            635..715
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            716..825
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            826..914
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1007
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1103
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1193
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1259
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1787
                     /gene="Gpr89b"
                     /gene_synonym="Gpr89; RGD1304837"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgaaggcc gcctaacaca gcaagtggac aggtcttagc aagcggctgg cttctctgag
       61 gtgtagacag ctgggcatgg gcctcccgag gcttcgccat gagcttcttg atcgactcca
      121 gcatcatgat cacctcccag atactgttct ttggattcgg gtggcttttc ttcatgcgcc
      181 agttgtttaa ggactatgag gttcgtcagt atgtggtgca ggtgatcttc tccgtgacct
      241 ttgcgttttc ctgcaccatg ttcgagctta tcatctttga aatcttggga gttctgaaca
      301 gcagctcccg ttactttcac tggaaaatga acctgtgtgt cattctgctc atcctggttt
      361 tcatggttcc cttctacatt ggttatttta tcgtgagtaa catccaactg ttgcacaaac
      421 agcgtctgct cttttcctgt ctcttatggc tgacctttat gtacttcttc tggaagctgg
      481 gagatccatt ccccatactc agcccaaaac atgggatctt gtccatagag cagctcatca
      541 gccgggtagg tgtgattggg gtgacactca tggctctgct ttccggattc ggtgctgtca
      601 actgccccta cacatacatg tcctacttcc tcaggaatgt gactgacacg gatatccttg
      661 ccctggaacg gcgactgctg cagaccatgg acatgatcat aagcaaaaag aaaaggatgg
      721 cggtgacccg gagaacaatg ttccagaggg gggatgtgca gaacaagcca tcgggactct
      781 ggggcatgct gaagagtgtc actgcctcgg ccccaggaag tgaaaatctg actcttatcc
      841 aacaggaagt agatgcttta gaagaactga gcaggcagct tttcctggaa acagccgatc
      901 tgtatgctac aaaggaaaga attgaatact ccaaaacatt caaggggaaa tattttaatt
      961 tcctgggtta ttttttctct atttattgtg tctggaaaat ttttatggca accatcaata
     1021 ttgttcttga tcgggttggg aaaactgacc ctgtcaccag aggcatcgag atcactgtga
     1081 attatctggg aatccagttc gatgtgaagt tctggtctca gcacatttct ttcatcctgg
     1141 ttggaataat cattgtcacg tccatcaggg gactgctgat cacacttacc aagttctttt
     1201 acgccatctc cagcagtaag tcctccaatg tcatcgtcct gctcttagca cagataatgg
     1261 gaatgtactt tgtgtcctct gtactgctga tccgaatgag tatgccccca gaataccgca
     1321 ccataatcac agaggtcctt ggagagcttc agttcaactt ctatcaccgc tggtttgacg
     1381 tcatcttcct ggtcagtgcc ctctccagca tattgttcct ctatctggct cacaagcagg
     1441 cgccagagaa gcatatggcc ccttgaactc agaccgcctg ccaacttcag gaaagaagac
     1501 acagtgggga tgccagagcc tagagctctt tagaacaggc atcgctgcaa ggtctgttct
     1561 gcctcgggcg catatgccta cttcctcctg aggtactgga gtcgtgagta gcctcagcta
     1621 aggcacaaga agaagatcca cagcactcag cggggagcac gtatgggtct gaggctgtgc
     1681 aaagtgagga ggagagggcc agggctgaga atatccggga gctcctgcgt ggatggcttc
     1741 ccttgaaaat actagtaaaa tcagagtttg taacactttg gccttgaaaa aaaaaaaaaa
     1801 aaaaaaaaaa aaaaaaaaaa aaaa
//
