LOCUS       NM_001169132             960 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 31 (Gpr31), mRNA.
ACCESSION   NM_001169132 XM_001070058 XM_217867
VERSION     NM_001169132.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Mashiko,M., Kurosawa,A., Tani,Y., Tsuji,T. and Takeda,S.
  TITLE     GPR31 and GPR151 are activated under acidic conditions
  JOURNAL   J Biochem 166 (4), 317-322 (2019)
   PUBMED   31119277
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Morita,N., Umemoto,E., Fujita,S., Hayashi,A., Kikuta,J., Kimura,I.,
            Haneda,T., Imai,T., Inoue,A., Mimuro,H., Maeda,Y., Kayama,H.,
            Okumura,R., Aoki,J., Okada,N., Kida,T., Ishii,M., Nabeshima,R. and
            Takeda,K.
  TITLE     GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by
            bacterial metabolites
  JOURNAL   Nature 566 (7742), 110-114 (2019)
   PUBMED   30675063
REFERENCE   3  (bases 1 to 960)
  AUTHORS   Zhang,X.J., Cheng,X., Yan,Z.Z., Fang,J., Wang,X., Wang,W.,
            Liu,Z.Y., Shen,L.J., Zhang,P., Wang,P.X., Liao,R., Ji,Y.X.,
            Wang,J.Y., Tian,S., Zhu,X.Y., Zhang,Y., Tian,R.F., Wang,L.,
            Ma,X.L., Huang,Z., She,Z.G. and Li,H.
  TITLE     An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic
            ischemia-reperfusion injury
  JOURNAL   Nat Med 24 (1), 73-83 (2018)
   PUBMED   29227475
REFERENCE   4  (bases 1 to 960)
  AUTHORS   Fehrenbacher,N., Tojal da Silva,I., Ramirez,C., Zhou,Y., Cho,K.J.,
            Kuchay,S., Shi,J., Thomas,S., Pagano,M., Hancock,J.F., Bar-Sagi,D.
            and Philips,M.R.
  TITLE     The G protein-coupled receptor GPR31 promotes membrane association
            of KRAS
  JOURNAL   J Cell Biol 216 (8), 2329-2338 (2017)
   PUBMED   28619714
REFERENCE   5  (bases 1 to 960)
  AUTHORS   Guo,Y., Zhang,W., Giroux,C., Cai,Y., Ekambaram,P., Dilly,A.K.,
            Hsu,A., Zhou,S., Maddipati,K.R., Liu,J., Joshi,S., Tucker,S.C.,
            Lee,M.J. and Honn,K.V.
  TITLE     Identification of the orphan G protein-coupled receptor GPR31 as a
            receptor for 12-(S)-hydroxyeicosatetraenoic acid
  JOURNAL   J Biol Chem 286 (39), 33832-33840 (2011)
   PUBMED   21712392
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 18, 2009 this sequence version replaced
            XM_001070058.1, XM_217867.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR26360194.2422223.1,
                                        SRR26360176.1752714.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-960               JAXUCZ010000001.1  55474484-55475443   c
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..960
                     /gene="Gpr31"
                     /note="G protein-coupled receptor 31"
                     /db_xref="GeneID:292310"
                     /db_xref="RGD:1305187"
     CDS             1..960
                     /gene="Gpr31"
                     /codon_start=1
                     /product="12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid
                     receptor"
                     /protein_id="NP_001162603.1"
                     /db_xref="GeneID:292310"
                     /db_xref="RGD:1305187"
                     /translation="MERTNCSAASPVVETAVGAMLTLECVLGLMGNAVALWTFFYRLK
                     VWKPYAVYLFNLVVADLLLATSLPFLAAFYLKGKTWKLGHTPCQVLLFLLTFSRGVGV
                     AFLTTVALDRYLRVIHPRLRVNLLSLKAAWGISSLIWLLMVVLTPQNLLICKTTQNST
                     ECPSFYPVGETKASATCQEVLFFLQVLIPFALISFCNSELIRTLQKRLRESDKQPRIR
                     RARVLVAMVLLLFGLCFLPSVLTRVLVHIFQEFESCTVQKAMVQASDIAGSLTCLHSA
                     LSPAIYCFSNPAFTHSYRKVLKSLRGMRKVAESPSSNLRDSIS"
     exon            1..960
                     /gene="Gpr31"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagcgca ccaactgctc agcggccagc cctgtggtgg agacagccgt gggcgccatg
       61 ctgacactgg agtgtgtgct gggccttatg ggcaatgctg tggccctctg gaccttcttt
      121 taccgtctca aagtgtggaa gccttatgcc gtctacctgt tcaacctggt ggtggctgac
      181 ctgctgctgg ccaccagtct gccattctta gctgccttct atctgaaggg caagacctgg
      241 aagctcggcc acacgccctg ccaagtcctg ctcttcctgc tgacattcag ccgtggtgtg
      301 ggggtagcct tcctgacgac agtggctcta gaccggtatc tgcgtgtgat ccatcctcgg
      361 ctcagagtta acttgctgtc tctgaaggca gcttggggca tctccagcct catctggctt
      421 ctgatggttg ttctcactcc ccaaaacctg ctcatttgca agactaccca gaattccacg
      481 gagtgcccca gcttctaccc cgtaggagag accaaagcca gtgccacctg ccaggaggta
      541 ctcttcttcc ttcaggtcct gattcccttt gccctcatct ccttctgcaa cagtgagctc
      601 atcaggaccc tccagaagag actccgagag tctgacaaac agcccaggat ccggagggcc
      661 agggtgctgg ttgccatggt gctgctactg ttcgggctgt gcttcctgcc tagcgtcctg
      721 accagggttc tggtgcacat ctttcaggaa tttgagagct gcactgtcca gaaagccatg
      781 gtgcaggcct ctgacatcgc aggcagcctc acctgcctgc acagtgcact gagcccggcc
      841 atttactgct tctccaatcc agccttcacc cactcatacc ggaaggtgct caaaagcctt
      901 cggggcatga ggaaggtagc agaatcacct agctccaacc tcagggactc catttcctga
//
