LOCUS       NM_022216               1670 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 20 (Gpr20), mRNA.
ACCESSION   NM_022216
VERSION     NM_022216.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1670)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   2  (bases 1 to 1670)
  AUTHORS   Hase,M., Yokomizo,T., Shimizu,T. and Nakamura,M.
  TITLE     Characterization of an orphan G protein-coupled receptor, GPR20,
            that constitutively activates Gi proteins
  JOURNAL   J Biol Chem 283 (19), 12747-12755 (2008)
   PUBMED   18347022
  REMARK    GeneRIF: GPR20 constitutively activates G(i) proteins without
            ligand stimulation
REFERENCE   3  (bases 1 to 1670)
  AUTHORS   Herold,C.L., Qi,A.D., Harden,T.K. and Nicholas,R.A.
  TITLE     Agonist versus antagonist action of ATP at the P2Y4 receptor is
            determined by the second extracellular loop
  JOURNAL   J Biol Chem 279 (12), 11456-11464 (2004)
   PUBMED   14670966
  REMARK    GeneRIF: second extracellular loop and the NH(2) terminus form a
            functional motif that plays a key role in determining whether ATP
            functions as an agonist or antagonist at mammalian P2Y(4) receptors
REFERENCE   4  (bases 1 to 1670)
  AUTHORS   Bogdanov,Y.D., Wildman,S.S., Clements,M.P., King,B.F. and
            Burnstock,G.
  TITLE     Molecular cloning and characterization of rat P2Y4 nucleotide
            receptor
  JOURNAL   Br J Pharmacol 124 (3), 428-430 (1998)
   PUBMED   9647463
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 25, 2020 this sequence version replaced NM_022216.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1670              JAXUCZ010000007.1  107490795-107492464 c
FEATURES             Location/Qualifiers
     source          1..1670
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1670
                     /gene="Gpr20"
                     /gene_synonym="Gpcr5-1; P2Y4"
                     /note="G protein-coupled receptor 20"
                     /db_xref="GeneID:60667"
                     /db_xref="RGD:620034"
     exon            1..1670
                     /gene="Gpr20"
                     /gene_synonym="Gpcr5-1; P2Y4"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..1083
                     /gene="Gpr20"
                     /gene_synonym="Gpcr5-1; P2Y4"
                     /note="G protein-coupled receptor 5-1"
                     /codon_start=1
                     /product="G-protein coupled receptor 20"
                     /protein_id="NP_071552.2"
                     /db_xref="GeneID:60667"
                     /db_xref="RGD:620034"
                     /translation="MPSALSSRPWDAVFPNTTTAAWTNGSVPETPLFYLFARLDEELH
                     ATFPSLWLALMVVHGTIFLAGLFLNGLALYVFCCRTRAKTPSVTYTINLVVTDLLVGL
                     SLPTRFAVFYGARGCLHCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVQPEGSHRWR
                     QPACAKAVCVFVWLAAGVVTLSVLGVKTGGRSCCRVFALTVLEFLLPLLVISVFTGRI
                     MCALSRPGLLRQGRQRRMRAMQLLLTVLVIFLVCFTPFHARQVTVALWPNVPYHTSLV
                     AYHVAVTLSSLNSCMDPIVYCFITSGFQATVQGLFYQRGEEFKPSTMDMVSMHKSTKG
                     SAPIHILSTGSHTLTQPLTNGPEP"
ORIGIN      
        1 atggccatgc cctctgcgtt gtcttcgagg ccctgggatg ctgtgttccc caataccact
       61 acagcagcat ggaccaatgg aagtgtgcca gagactcccc tgttctacct attcgcccgg
      121 ctggatgagg aacttcatgc caccttcccc agcctgtggc tggcactaat ggtcgtgcat
      181 ggcaccatct tccttgccgg gctgttcctc aatggactgg cgctgtacgt cttctgctgc
      241 cgcacgcggg ccaagacacc ttcagtcacc tataccatca acctggtggt gactgacctg
      301 ctggtgggcc tgtccctgcc cacacgcttt gcagtcttct acggtgcccg cggctgccta
      361 cactgtgcct tccctcacgt cctgggctac ttcctcaaca tgcactgttc tatcctcttc
      421 ctcacctgca tctgtgtgga ccgctacctg gccattgtgc aacctgaggg ctcccatcgc
      481 tggcgccagc cggcctgcgc caaggctgtg tgcgtctttg tgtggctggc agcgggagtc
      541 gtgaccctgt ctgtattggg tgtgaagact ggtggacggt catgctgccg ggtctttgct
      601 ctgaccgttc tggagttcct gctgccgcta ctggtcatca gcgtgttcac aggccgtatc
      661 atgtgtgcac tgtcgaggcc aggcctgcta cgccagggtc gtcagcggcg catgagggcc
      721 atgcagctgc tgctcacggt gctggtcatc ttcctggtct gtttcacacc cttccatgcc
      781 cgccaggtga ctgtggcact gtggcccaat gtgccttacc ataccagcct tgtggcttac
      841 catgtggccg tcaccctcag cagcctcaac agctgcatgg accccatcgt ctactgtttt
      901 atcaccagtg gtttccaggc cactgtccaa ggcctcttct accagcgtgg agaagaattc
      961 aagcccagca ctatggatat ggtcagcatg cacaagagca ccaagggctc agcccccatt
     1021 cacatcctca gcaccggttc tcacaccctc acccagcctt tgaccaacgg gcctgagcca
     1081 taggtagcag tactccacca agggtcgaag gtcaaggctc tgaaaggtta ccaaccagac
     1141 atatcctggt cctggacagc agttaatttc ctattgctct gttggatatg actgttcagt
     1201 gtgttgtgtt gacaaactga gcccactgtg ctgtgattga ttagcagtgt ctgcaagggc
     1261 tccagatagg gtataatgat ataaatgctg gatgcttgcc tttcctatgg ttatgtagta
     1321 tccactgaac actcaaaaag gtatctagga gctgctccta gcctctgtga attgttccct
     1381 gaagaagctc ttccagagaa agcacaaaga tcaatgttct gatgactcca ggaaggttaa
     1441 acccaaccag aagagtctcc actacaggta gatggagaaa caagagtaga tggtcagtgt
     1501 tttgggggca atagtgttat gtacagggag tagagacacc ccagacttct gtgaactaca
     1561 ccacaagcca gcatagcaat acaaggtggc cctctgtgta ccaggagttg gacttgggta
     1621 tcctggttga catttgaacc actgcaaccc caaatgaaga agctagtgca
//
