LOCUS       NM_001270986            3824 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 176 (Gpr176), mRNA.
ACCESSION   NM_001270986 XM_342493
VERSION     NM_001270986.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3824)
  AUTHORS   Doi,M., Murai,I., Kunisue,S., Setsu,G., Uchio,N., Tanaka,R.,
            Kobayashi,S., Shimatani,H., Hayashi,H., Chao,H.W., Nakagawa,Y.,
            Takahashi,Y., Hotta,Y., Yasunaga,J., Matsuoka,M., Hastings,M.H.,
            Kiyonari,H. and Okamura,H.
  TITLE     Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets
            the pace of circadian behaviour
  JOURNAL   Nat Commun 7, 10583 (2016)
   PUBMED   26882873
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3824)
  AUTHORS   Hata,S., Emi,Y., Iyanagi,T. and Osumi,T.
  TITLE     cDNA cloning of a putative G protein-coupled receptor from brain
  JOURNAL   Biochim Biophys Acta 1261 (1), 121-125 (1995)
   PUBMED   7893747
REFERENCE   3  (bases 1 to 3824)
  AUTHORS   Ishizaka,N., Okazaki,H., Kurokawa,K., Kumada,M. and Takuwa,Y.
  TITLE     Molecular cloning of a novel putative G protein-coupled receptor
            from rat aortic smooth muscle. Downregulation of the mRNA level by
            the cyclic AMP messenger pathway
  JOURNAL   Biochim Biophys Acta 1218 (2), 173-180 (1994)
   PUBMED   8018717
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Aug 18, 2012 this sequence version replaced XM_342493.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.18156.1,
                                           SRR26360190.1249992.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-354               JAXUCZ010000003.1  125790819-125791172 c
            355-607             JAXUCZ010000003.1  125697510-125697762 c
            608-3824            JAXUCZ010000003.1  125690751-125693967 c
FEATURES             Location/Qualifiers
     source          1..3824
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..3824
                     /gene="Gpr176"
                     /gene_synonym="Gm1012; Gpr; RBU-15"
                     /note="G protein-coupled receptor 176"
                     /db_xref="GeneID:117257"
                     /db_xref="RGD:621718"
     exon            1..354
                     /gene="Gpr176"
                     /gene_synonym="Gm1012; Gpr; RBU-15"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1727
                     /gene="Gpr176"
                     /gene_synonym="Gm1012; Gpr; RBU-15"
                     /note="G-protein coupled receptor AGR9; putative G protein
                     coupled receptor"
                     /codon_start=1
                     /product="probable G-protein coupled receptor 176"
                     /protein_id="NP_001257915.1"
                     /db_xref="GeneID:117257"
                     /db_xref="RGD:621718"
                     /translation="MGHNGSWVSPNTSHPRNTSGAQAGANSSAFGELSEAQLYRQFTT
                     TVQVVIFIGSLLGNFTVLWSTCRTTVFKSVTNRFIKNLACSGICASVVCVPFDIILST
                     SPHCCWWIYTMLFCKVLKFLHKVFCSVTVLSFPAIALDRYYSVLYPLERKISDAKSRE
                     LVMYIWAHAVVASVPVFAVTNVADIYATSTCTEVWSNSLGHLVYVLIYNVTTVIVPVA
                     VVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVTVFIL
                     CSVPYATLVVYQTVLNVPNTSVFLLLTAIWLPKVSLLANPVLFLTVNRSVRKCLVGTL
                     VQLHHRYSRRNVVSTGSGVVEPSLEPSMRSGSQLLEMFHIGQQQIFKPSEDEEESEAK
                     YLGSTDFQAKEVLTSSPEGEESQLAPSVPPPGTVDSVSRVSPVAPVEPGIFPDKYSLQ
                     FGFGPFELPPQWLSETRNSKKRLLPPLGNTPEELIQTKVPRVSRVERKMSRNNKVSIF
                     PKVDS"
     exon            355..607
                     /gene="Gpr176"
                     /gene_synonym="Gm1012; Gpr; RBU-15"
                     /inference="alignment:Splign:2.1.0"
     exon            608..3824
                     /gene="Gpr176"
                     /gene_synonym="Gm1012; Gpr; RBU-15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccctcccac cccatctcga ggacggctgg ttaggcgatg agcagacgtg aggggctagc
       61 cggctgcccg gctctgcagg acgctgcctg gctcccgagc gtcggtccct ccgcgcccgg
      121 ggcaggagcg gctgtgcgct ggggctcaga ggccgggcag gagagtacaa gcccccggct
      181 tcgctatggg gcacaacggc agctgggtgt caccgaacac cagccacccg cgtaacacgt
      241 cgggcgccca ggctggcgcc aacagcagcg cgttcgggga gctgagcgag gcgcagctgt
      301 accgccagtt caccaccacc gtgcaggtcg tcatcttcat tggttcgctg ctcgggaact
      361 tcacggtgtt atggtcaacc tgccgcacga ccgtgttcaa atctgtcacc aacaggttca
      421 ttaaaaacct ggcctgctcc gggatttgtg ccagcgtggt ctgcgtgccc ttcgacatca
      481 tcctgagcac cagccctcac tgctgctggt ggatctacac gatgctcttc tgcaaggtgc
      541 ttaaattcct acacaaggtg ttctgctcgg tgactgtcct cagctttcct gccattgccc
      601 tggacaggta ctattcagtc ctctaccctc tggagagaaa aatctctgac gccaagtctc
      661 gggaactagt gatgtacatc tgggcccatg cagtggtggc cagcgtccct gtgtttgctg
      721 tgaccaatgt agctgacatc tatgctacat ccacctgcac ggaagtctgg agcaactcct
      781 tgggccacct ggtgtatgtc ctgatctaca acgtcaccac ggtcattgtg cctgtggctg
      841 tggtattcct ctttcttatc ctgatccgga gggccctgag tgccagtcag aagaagaaag
      901 tcatcatcgc tgcactgagg accccacaga acaccatctc tatcccctat gcatcccagc
      961 gggaggcaga gctacatgcc accctgctct ccatggtgac agttttcatc ctctgcagcg
     1021 taccctatgc caccctggtt gtctaccaga ctgtgctcaa tgtacctaac acttctgtgt
     1081 tcttgcttct cactgctatt tggctgccca aagtctcact gttggccaac cctgtgctct
     1141 tcctaactgt gaacagatca gtacgcaaat gcttggtggg gaccctggtg cagttgcacc
     1201 accggtacag tcgccgcaat gtggttagta cagggagtgg ggtggttgag cctagccttg
     1261 agcccagcat gcgctctggt agccagctct tggagatgtt ccacattgga cagcaacaga
     1321 tctttaagcc ctcggaggat gaggaagaga gtgaggccaa gtatcttggc tcaactgatt
     1381 tccaggccaa ggaggtactc acctcctccc cagagggcga ggagtcacag cttgcaccct
     1441 ctgtgccgcc tccaggcaca gtagactctg tatctcgggt gtccccagta gcccccgtgg
     1501 aacctggcat attccctgat aagtattccc tgcagtttgg ctttgggcct ttcgagttgc
     1561 cccctcagtg gctctctgag actcgaaata gcaagaagag gctgcttccc ccactgggca
     1621 ataccccaga agagctgatc cagacaaagg tgcccagagt gagcagggtg gagcggaaga
     1681 tgagcagaaa caataaagtg agcatttttc caaaggtaga ctcctagcga ggactatgag
     1741 tgcctgagag tgtaagggag cttgtatatt cctgttctcc cttccctctg gctgccactg
     1801 tggggcgata actcctttac atggcaaatg cttctgaatg aaagggaagt ctacagaaaa
     1861 cccaatgtcc tctttattga gggagtatat atctatctta gtgatctgtg tccttcatca
     1921 cattcagtgt aagctgggca gaatggaaca ggtctgaggg ctctctgaca cattttctgg
     1981 gagattcctc ctttttttgt gtgcagcaaa gaactcaaat ggagcaggca ctccaaggag
     2041 gcccaggata attctgggct tcaatggcca cagagaagaa gctaatttgt ttttaaaatg
     2101 tttgttttgt tttgttttgt tttttttttt ttgagactgg atttctctat gtagccccac
     2161 cctacagatt gggctggcct tgaactcaga gagccacctg tctctgcctt ctgagtgctg
     2221 ggcttaaagg tctgtgccca catgcccact taagaagcct atttgggtag ctaaataaga
     2281 ataacaaata ggaaaatatc tgagaagaca gagccatggt gtcgaatggt ttttgctaga
     2341 tttcacaatc acccaactcc tggttgctaa tacccctcgt ctggatttct gggtcataaa
     2401 gggggggatg actggattta tcttaggata gacagggcag tgtctgaggg agcctttttg
     2461 tccttgatta tctctccacc ctgttggtat caccaaggcc tccaacaaat gtacctgctt
     2521 ccaccagtca gccatgctgc ctggaaacca ctgccaacca ttcactgtgt gtccatttta
     2581 tcagcaacaa gaagggaaga tttgtggtgg cgaagacagg ctgagaaatg cccaccatga
     2641 ataacctttt ttctctctca cgtgattaag agcaaaagac tagactcagt ataggggggt
     2701 ataggcacaa agtaaaacgt cctaactggc aaatgtttgg aattaaaagg tgcttaagaa
     2761 atgtaggtgg catgcactgg gtcgtttggc accattaagg taaaaatcct tgattagcac
     2821 aagcgactct gccctaagac ttattagttt gacatacagg acacgcccac ccgccagtct
     2881 cattttcagt gtgttctgat tctggatccc acagaaggtg agcagagcag gagaaataat
     2941 gattgcaaat gctaaagcaa ttcccaccct gatttagcac tccatcctct acttccaatg
     3001 aagttcaggt atgagccatg gtggatggga gaatgtgctc tctcagcagc tcagtgccct
     3061 ggctctcatg tgtgagccac tctgggactg atgtaccaga cctaattcaa acccaactct
     3121 cccctcatac atcaagttgg gagctctgct cttcttaggg tgttttgttc ttgtttgtgg
     3181 tccttggtgg agccagtcgg gcaccttgaa tggataggta ttcctacgag caaacttcta
     3241 catctcaaag gcagtggtcc tagcagcacg tttagccatg ctggcccatc gcccctaaga
     3301 ggaagctcag cccgtgtata gggagactcc ttttcttttc ttctattgtg ttatgtcttg
     3361 tgaaccccaa catctcctcc ttggagaggg ggcgccttcc tttctgtgca ctgcctcaca
     3421 gacttgtttt ctcacgtcag agacagggta ctgtgcccct cttgtggctc tgtggccctc
     3481 tgggccctgt gtacctgcca tctgtagctc tttgtcctga tgctgtgtta atgctgtggc
     3541 cctccaagct catctttcaa agccttctta attgttacag cttttactaa ggggaaaaat
     3601 aatccctcag agaatcctat gtaccagaga agaacctgtg aaatgtacgt gtgttgctgt
     3661 cgtcctgacc tgtatgtgtg acttaataaa ttctcaacag cggagtttgg ttcaccaaat
     3721 tctcatgtat gttggaaaga gaaggctgac gtctagcagg ctgtcgccga gtgtatttct
     3781 atactctttg aagaataaca ttttaataaa aattataaag ctgt
//
