LOCUS       NM_001107811            4810 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 155 (Gpr155), mRNA.
ACCESSION   NM_001107811 XM_001062029 XM_230989
VERSION     NM_001107811.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4810)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 4810)
  AUTHORS   Nishimura,Y., Martin,C.L., Vazquez-Lopez,A., Spence,S.J.,
            Alvarez-Retuerto,A.I., Sigman,M., Steindler,C., Pellegrini,S.,
            Schanen,N.C., Warren,S.T. and Geschwind,D.H.
  TITLE     Genome-wide expression profiling of lymphoblastoid cell lines
            distinguishes different forms of autism and reveals shared pathways
  JOURNAL   Hum Mol Genet 16 (14), 1682-1698 (2007)
   PUBMED   17519220
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473949.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001062029.1, XM_230989.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4810
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..4810
                     /gene="Gpr155"
                     /note="G protein-coupled receptor 155"
                     /db_xref="GeneID:311730"
                     /db_xref="RGD:1309162"
     exon            1..207
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            208..692
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..2845
                     /gene="Gpr155"
                     /note="integral membrane protein GPR155"
                     /codon_start=1
                     /product="lysosomal cholesterol signaling protein"
                     /protein_id="NP_001101281.1"
                     /db_xref="GeneID:311730"
                     /db_xref="RGD:1309162"
                     /translation="MDSYFPAKNSTLAVNMNETLSASHGFNSTSDPPPMSITRLFPAL
                     LECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFANVDWAFLY
                     SILIGKASVFFVVCVLTLLVASPESRFSKAGLFPIFATQSNDFALGYPIVEALYQTTY
                     PEYLQYIYLVAPISLMMLNPIGFIFCEIQKSKDTRNASQNKAKIVGLGFLRVLQNPIV
                     FMVFVGIAFNFILDKKIPVYMENFLDGLANSFSGSALFYLGLTMVGKIRRLKKSAFVA
                     LIVLITAKLLVLPLLCREMVEVLDKGNSVVNHTSLSNYAFLYGVFPVAPGVAIFATQF
                     NMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDAKPLAYAIQNVSFDISIISLVSL
                     IWSLSVLLLSKKYKQLPHMLTANLLIAQTIVCAGMVIWNFVKEKNFVGQILVFVLLYS
                     SLYSTYLWTGLLAVSLFLLKKRESVQIPVGLIIISGWGIPALLVGVLLITGKHNGDSV
                     DSAFFYGKEQMITTAVTLFCSILIAGVSLMCMNRTTQAGHYEGFGQSQSHKPVEPGST
                     AFEESPAPTSEPELFPSSIPETGCCSCSLGNGELRCPSIQPGTNSSASRPRPSSFEKT
                     DQCVSRCDSQSCILAQEEEQYLQSGDPQLTRHVLLCLLLIIGLFANLSSCLWWLFNHE
                     TGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWNNKETAEDRESP
                     VSEEIKMTCQQFVHYHRDLCIRNIVRERRCGAKTSAGTFCGCDLVNWLIEVGLASDRG
                     EAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPERSPPAGTVSNPPEESYKEI
                     GHASPPSLSPKT"
     exon            693..1092
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1258
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1414
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1498
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1616
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1701
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1792
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..2003
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2108
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            2109..2245
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            2246..2341
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            2342..2406
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            2407..2544
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
     exon            2545..4810
                     /gene="Gpr155"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggtacccgg ccgcagacgc ctaaggtagc tgacaggccc gcagcggctc acccctccct
       61 tttctcggaa cgtggttggg catctgctgc tggctcaagc ctttagaaga gggctccggg
      121 caggagatga cggcagtgtg ctcgctgcct agtcctctgc gagcaccggc ttccttctcc
      181 tcgcagccgg agctgcaaac ctagcagaga ccagtctgga agtacaggga gagggaagat
      241 ggattcttat ttcccagcaa agaactcaac tcttgctgtt aatatgaatg agactttgtc
      301 tgccagtcat ggctttaatt ccaccagtga cccacctccg atgtcaataa ccaggctctt
      361 cccagcgtta ctcgagtgct ttggcatcgt cctttgtggg tacatagcgg gaagggccaa
      421 tgtcataaca tccacacagg ccaaaggact gggaaacttc gtctccagat ttgccctccc
      481 agctttatta ttcaaaaaca tggttgtgct taattttgcc aatgtggatt gggcttttct
      541 atatagcatc ctaattggca aggcctctgt atttttcgtt gtatgcgtgt taaccctgtt
      601 ggttgccagt cctgagagtc gatttagcaa agctggactg ttccctatct ttgctacaca
      661 gagcaatgac tttgctttgg gataccctat agttgaagct ctgtaccaaa ccacataccc
      721 agaatatctc cagtacattt atttggtggc accaatatct cttatgatgt taaaccctat
      781 agggttcatc ttctgtgaaa tccagaagtc aaaagacact cgaaatgctt ctcaaaacaa
      841 agcaaaaatt gtgggacttg gattcctgcg cgtgttacag aacccgatag tgtttatggt
      901 cttcgttggc atcgccttca attttattct tgataaaaag atccctgtgt atatggaaaa
      961 ttttcttgat gggcttgcaa actccttctc tgggtcagcc ctgttctatc tcggtctgac
     1021 catggtagga aaaatcaggc ggctgaagaa gtcggcgttc gtggcgctca ttgtcctcat
     1081 cacagctaaa ctcctggtgc tgccccttct gtgcagagaa atggtggaag tcctggacaa
     1141 gggtaacagc gtagtgaacc acacgagtct gtccaactat gcgtttctct atggcgtctt
     1201 ccctgtggct ccaggagtgg ctatctttgc aacacaattc aacatggaag tggagatcat
     1261 aacctcagga atggtcataa gtacatttgt gtctgctcca atcatgtatg tttctgcctg
     1321 gttattgacc tttcctacca tggatgctaa gccactggca tatgccattc agaatgttag
     1381 ctttgacata agcattatca gcctggtctc cttgatctgg tctctgtctg ttcttctctt
     1441 gagtaagaag tataagcagc ttcctcacat gctcacagct aacctactca tcgctcagac
     1501 tattgtttgc gctggaatgg tgatatggaa ttttgttaaa gaaaaaaatt ttgttggaca
     1561 aattttggtg tttgttttat tgtacagctc cctgtacagc acctatctat ggacaggcct
     1621 tctagcagtt tctttgtttc ttttaaagaa gcgggagagc gttcagatcc cagtgggcct
     1681 catcatcata tctggctggg gaatccctgc tctcctcgtg ggcgtgcttc tgataactgg
     1741 aaaacacaat ggagacagcg ttgactcggc tttcttttat ggaaaagagc agatgatcac
     1801 cacagcagtc accctgttct gcagcattct catagctggg gtgtcactca tgtgcatgaa
     1861 ccgtaccacc caagctggcc actacgaagg tttcggccag tctcagagtc acaaaccggt
     1921 agagcctgga agcactgcgt tcgaggagag cccagcgcca acaagtgaac cagagctctt
     1981 cccaagttct atcccagaaa caggttgctg ttcttgctcc ttgggaaatg gtgaattacg
     2041 ctgtccatca atacagccag gaacgaactc aagtgctagc aggcctaggc cttcttcctt
     2101 tgagaaaacc gaccagtgtg tgagccgctg tgactcccag agctgcatcc tcgcccagga
     2161 agaagagcag tacctgcaga gtggagaccc gcagctgacc cgtcacgttc tgctgtgcct
     2221 gctgctcatc atcggcctgt ttgctaatct ctctagctgt ctctggtggc tctttaacca
     2281 cgagacagga cggctctacg ttgaattaca gtttttctgt gctgtgttta acttcggcca
     2341 gggatttatt tccttcggaa tttttgggtt ggacaaacat ctaatcatcc tacctttcaa
     2401 aagaaggctt gaattcctgt ggaacaataa agaaacagca gaagacagag aatccccggt
     2461 ttccgaggaa ataaaaatga cctgtcaaca gtttgtacat tatcaccgtg acctgtgcat
     2521 ccgaaacatc gtcagagaaa gaaggtgtgg tgcaaagacg tctgccggga ccttctgtgg
     2581 ctgtgacctg gtgaactggc tcatcgaagt cggcctagct tctgaccgtg gcgaagctgt
     2641 gatctatgga gacagactgg tgcaaggggg agtcatccag cacatcacca atgaatatga
     2701 gtttcgggac gagtatttgt tttacagatt tcttcaaaag agtcctgaac ggagtcctcc
     2761 tgccggcact gtaagcaacc ccccagaaga aagctataaa gaaattggtc acgcgtctcc
     2821 gccctcactc tcccctaaga cttaagatcc agagagagcc ccgcaggacc acaccctcta
     2881 gcctcaaatc tgatcctttt agctgtggga ccctgggcag gtcatctctt ctgtaaaatg
     2941 acaaaggcaa tcctaccttg tactgacatc ccataacttt acgtgtctat agagcacata
     3001 ggaaactgac aagagatttc acaaagttaa aggttatgat aatgaataca gcagttgcta
     3061 aagataccac tgctgtccca acattttaaa aatcatctct ttctgaaact gttatcatta
     3121 tagagtcagt atccagctgg ctgtgatttt aagttgccaa atgtggcagg tttgctgctc
     3181 tcaaaaggaa ccttaggaca acctcacatt tatcaataac acttcccccc aacagatttt
     3241 tacttattct agtaaaagct tttattttcc ttcccacttc tttgacaaat actacctatt
     3301 cgaaaattac aactactgtt ctgtttttga gccaaggtct catgatgtag cccaggctgg
     3361 cctcaaattc ctatgtagcc aggaatggtt tttaactact gatcttcctg cctctgccta
     3421 ctgagttctg gactttttgg tgtgtgccaa catgcccggc taaccccagt atttttttaa
     3481 agtaattttt aaatttattt ttgataaaac accagtttta aaggtttttg tcttttcttg
     3541 ttttctatct acattacaaa tgtgtaccaa taagaagaga ataagaacat tactatctct
     3601 ataatctttt aagataaaaa ttttaaataa tttgaactta ttcatttaaa tgttatttaa
     3661 gaaataatgc caagcaatgt actgtttctg atagaagaaa aatccacttt attccctgca
     3721 ttgagaaagt atatagtcag gaacttaaaa ttctaagcct agcaacctac cttagaattt
     3781 agtcctttct gtgtccatgt ctaaaaaatt tgtaagttta aaaattagta agtgttgctt
     3841 agtccattga gattttagga cagaatgaca ggaacacaac tagttactaa gcaacaggga
     3901 ggcttcctta cagatctggg gctggcagtg caagggtaaa cagctgcact ccacctctgc
     3961 tgaggcccct gcaggtccac caccctcgat gggagctgcc ctcggtggga gggaagggct
     4021 ctggaagaac aaaccgcatg ttggcacctc ttctctcatg agccacactt ctccaggtca
     4081 cctccctggg gttgggtttt gaagagacat gtccagacca ttacagcctc aggtaaagct
     4141 ttattctcag agaatttgca catcctttga acagctactt aattattaga tatcagtgat
     4201 ggtttaactt attctaaatg ttatttatct tattttagtg tttcatatat aaaagccatt
     4261 taggaaatta tttatagggt tagtgccctg gcccttctaa tgtagcaaat acataattaa
     4321 aagaaaacct tgcatggaag cctagtgtat ataaaaagaa atgatgttta ttttatgtta
     4381 caatcatgga agcgggatgt tttaggtaga actatagcac cataaaactt aggggaaaaa
     4441 agagacacgc tcacactgta ctcctagggc ccaggagtac acataagccc ccgccttagc
     4501 agcctccagt agcaagacaa aattcacatg tatgcgggca actcaaattc aagcgaggga
     4561 atctgttctg tttatgaata acccatatta actatgctct ttcatttgca caagtggaat
     4621 ctgaaacatc attgtctgtg ggaggctcta agagagaacc atagatcaga gtgactcgca
     4681 gtttcagatg ataaaggcgt ttagccatgc tcttaggagt aaggataagc taattttatt
     4741 aaaggaaatg tttgtatgtt actttctcac tgacagcacg tttctcaata aaatacctat
     4801 tttaacttgc
//
