LOCUS       NM_001034855            2675 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 153 (Gpr153), mRNA.
ACCESSION   NM_001034855
VERSION     NM_001034855.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2675)
  AUTHORS   Sreedharan,S., Almen,M.S., Carlini,V.P., Haitina,T.,
            Stephansson,O., Sommer,W.H., Heilig,M., de Barioglio,S.R.,
            Fredriksson,R. and Schioth,H.B.
  TITLE     The G protein coupled receptor Gpr153 shares common evolutionary
            origin with Gpr162 and is highly expressed in central regions
            including the thalamus, cerebellum and the arcuate nucleus
  JOURNAL   FEBS J 278 (24), 4881-4894 (2011)
   PUBMED   21981325
  REMARK    GeneRIF: antisense oligodeoxynucleotide knockdown of Gpr153 caused
            a slight reduction in food intake and elevated plus maze test
            showed significant reduction in the percentage of time spent in
            centre square, which points towards probable role in decision
            making.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC105872.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2675
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2675
                     /gene="Gpr153"
                     /note="G protein-coupled receptor 153"
                     /db_xref="GeneID:619550"
                     /db_xref="RGD:1564170"
     exon            1..222
                     /gene="Gpr153"
                     /inference="alignment:Splign:2.1.0"
     exon            223..690
                     /gene="Gpr153"
                     /inference="alignment:Splign:2.1.0"
     CDS             335..2044
                     /gene="Gpr153"
                     /codon_start=1
                     /product="probable G-protein coupled receptor 153"
                     /protein_id="NP_001030027.1"
                     /db_xref="GeneID:619550"
                     /db_xref="RGD:1564170"
                     /translation="MSDERRLPGSAVGWLACGGLSLLANAWGILSVGAKQKKWKPLEF
                     LLCTLAATHMLNVAVPIATYAVVQLRRQRPDYEWNEGLCKVFVSTFYTLTLATCFSVT
                     SISYHRMWMVRWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHG
                     CRFIVAEIGLGFGVCFLLLVGGSVAMGVVCTAIALFQTLATQVVSFSSLRADASAPWM
                     VLCVLWCSVTQALLLPLFLWTCDRYRADLKAVWEKCVALMANDEDSDNETSLEGSISP
                     DLVLERSLDYGGDFVALDRMAKYELSALEGGLPQLYPLRPLQEDRMQYLQGAGRHRCG
                     FPGGQPCFSPAGCSQVPPTRRFSHDDADVWAAIPLPTFLPRWSSGEDLAALAHLMLPA
                     GSDRRRGSLLAFTEDAPPFRPRRRSAESLLSLQPSSLDGGPRRAQDSPPGSPCRRPGP
                     GARSASVSLLPDAFALTAFDREPQPLRRVPAPARPFPAAPDGTETAEIPTPPGGRAQR
                     SQGRRAARAHAGPLQSSLSASWGEPGGLLAAGCGSTSSFLSSPSESSGYVTLHSDSLG
                     SAS"
     exon            691..940
                     /gene="Gpr153"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1133
                     /gene="Gpr153"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1312
                     /gene="Gpr153"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..2644
                     /gene="Gpr153"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggaggcgg cgcccaggga gggagggcgg cggggccgag cgcagcgcag cgctctggcc
       61 atcggcagct tccaccgcca gaatgccccg gcccgagggc cgctccgccg ccagctaccc
      121 ccgcggcccc tggcggcagg cgctcagtgc cggggcgcgg gaaccgcaac cggagccgga
      181 ggcgggagca gcgagccgga gccacgggcg cctcaatgct ggctgcttgt ggtccctggc
      241 atcaccgggc ccccacgtgt gagggctgcc gcattacaaa gaggcctggc tctgaggagg
      301 atgtcacggc cgctcgccag ctccagtctg catcatgagt gatgagcgga ggctgcccgg
      361 cagtgcggta ggctggctgg catgcggagg cctgtcgctg ctagccaatg cctggggcat
      421 cctcagtgtg ggtgccaagc agaagaagtg gaagccactg gagttcttgc tttgcacgct
      481 ggcagccacc cacatgctca acgtggcggt gcccatcgcc acgtacgcag ttgtgcagct
      541 gcggaggcag cgccctgact acgagtggaa cgagggcctc tgtaaggtct tcgtgtcgac
      601 gttctacacc ctcacgctgg ccacctgctt ctccgtcacc tccatctcct accaccgcat
      661 gtggatggtc cggtggccgg tcaactaccg gctgagcaac gccaagaagc aggcggtgca
      721 cacagttatg ggcatctgga tggtgtcctt catcctgtcg gcccttcctg ccgtcggctg
      781 gcacgacacc agcgagcgtt tctacaccca cggctgtcgc ttcatcgtgg ctgagatcgg
      841 cctgggcttc ggcgtctgtt tcttgctgct ggtgggaggc agcgtggcca tgggcgtggt
      901 ctgcacggcc attgccctct tccagacgct ggccacgcag gtggtgagct tcagtagcct
      961 gcgggctgat gcctcagcac cttggatggt gctctgtgtc ctgtggtgct ccgtgaccca
     1021 ggccctgctg ctgcctctgt tcctgtggac ttgtgatcgc taccgggcag acctcaaggc
     1081 agtctgggag aagtgtgtgg ccctgatggc caatgatgag gactcagaca acgagaccag
     1141 tctagagggt agcatctccc ccgacctggt attggagcgc tcccttgact atggaggtga
     1201 cttcgtggct ctggacagga tggccaagta tgaactctct gccctggagg gaggcttacc
     1261 ccagctctac cctctgcggc cactgcagga ggatcggatg cagtatctgc agggcgcggg
     1321 gaggcatcgg tgcgggtttc caggagggca gccctgtttc agcccggccg ggtgctcgca
     1381 ggtcccgccc acccggcggt tctcccacga tgatgccgac gtgtgggcgg ccatcccgct
     1441 gcccaccttc ctgccacgct ggagctcggg cgaggacttg gcagccctgg cacacttaat
     1501 gctgcctgcg ggctccgacc ggcggcgcgg gagcctgctg gccttcaccg aagatgcgcc
     1561 cccgttccgc ccgcgccgtc gttctgcgga gagcctgttg tccctgcagc cctcgtccct
     1621 agatggtggc ccgcgtcgcg cccaggactc gcctccgggc agcccgtgtc gccgccccgg
     1681 gcctggcgct cgctctgcct cggtctcgct gctgcctgac gccttcgcgc tgaccgcctt
     1741 cgaccgcgag ccgcagcctc tgcgtcgcgt gcccgctccg gcgcggccgt tccccgctgc
     1801 cccggacggc acggagactg ctgagatccc gacgccccct ggtggccgtg cgcagcgcag
     1861 ccagggacgc cgggcggcgc gcgcgcacgc ggggcccctg cagagcagcc tgagcgcgtc
     1921 ctggggcgag cccggcggct tgctcgcggc gggctgcggc agcactagca gctttctgag
     1981 ctcgccctcc gagtcctcgg gctatgtcac gctgcactcg gattcgctgg gctctgcgtc
     2041 ctagccaccc caccctcacc ccagacgcca tgcagacgga agaggcacag aactaaagat
     2101 gctgccacat gtgttaggcc ccaataagcg ccacctgtgc taggcagtga atgggtagtg
     2161 aacgcctctt acagttcctt ccttctgatg tcgcctggag ggacgatcgg tcaccttgga
     2221 gggctgccca ggacatgaac ctgctgctgg gcacggcatc tcccaggaag aggcaggctg
     2281 tgcctgtgta gcgagtggca tctgtacgtt ttgtacacct ctgaggctag accggggtgt
     2341 ggggaaccct gagatccgac catcattgga aaggacattc tcagagacgc ttaaaccgga
     2401 agtcacgact gcatccaact tcccgcacta ccgctgcctc acctctaggg tgtggcgtgt
     2461 agagagtccg caaacacggg tcttcagggc ccaaacaagt tctattgagc aggttttcct
     2521 tgtggcctgc ctcagcttcc ctatctccga agagtggatg accatgatac atctctcagg
     2581 gctgtttgaa gaacactccc gatccgtgtg ccctcgtatt tgaatagacc ggttgtgaga
     2641 ggtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
