LOCUS       NM_001107828            3950 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus G protein-coupled receptor 107 (Gpr107), mRNA.
ACCESSION   NM_001107828 XM_001079739 XM_231134
VERSION     NM_001107828.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3950)
  AUTHORS   Elrick,M.M., Samson,W.K., Corbett,J.A., Salvatori,A.S., Stein,L.M.,
            Kolar,G.R., Naatz,A. and Yosten,G.L.
  TITLE     Neuronostatin acts via GPR107 to increase cAMP-independent PKA
            phosphorylation and proglucagon mRNA accumulation in pancreatic
            alpha-cells
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 310 (2), R143-R155 (2016)
   PUBMED   26561648
  REMARK    GeneRIF: Neuronostatin acts via GPR107 to increase cAMP-independent
            PKA phosphorylation and proglucagon mRNA accumulation in pancreatic
            alpha-cells.
REFERENCE   2  (bases 1 to 3950)
  AUTHORS   Zhou,G.L., Na,S.Y., Niedra,R. and Seed,B.
  TITLE     Deficits in receptor-mediated endocytosis and recycling in cells
            from mice with Gpr107 locus disruption
  JOURNAL   J Cell Sci 127 (Pt 18), 3916-3927 (2014)
   PUBMED   24849652
REFERENCE   3  (bases 1 to 3950)
  AUTHORS   Yosten,G.L., Redlinger,L.J. and Samson,W.K.
  TITLE     Evidence for an interaction of neuronostatin with the orphan G
            protein-coupled receptor, GPR107
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 303 (9), R941-R949 (2012)
   PUBMED   22933024
  REMARK    GeneRIF: GPR107 is a promising candidate receptor for
            neuronostatin, and neuronostatin, interacting with GPR107, may play
            an important role in the central control of cardiovascular
            function.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079739.1, XM_231134.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3950
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..3950
                     /gene="Gpr107"
                     /note="G protein-coupled receptor 107"
                     /db_xref="GeneID:311857"
                     /db_xref="RGD:1305882"
     exon            1..156
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1689
                     /gene="Gpr107"
                     /note="protein GPR107"
                     /codon_start=1
                     /product="protein GPR107 precursor"
                     /protein_id="NP_001101298.1"
                     /db_xref="GeneID:311857"
                     /db_xref="RGD:1305882"
                     /translation="MAVRVPLGCTGSFCPRLLPLLALLELLVDPSLGRVHHLALKDDV
                     RHKVHLNTFGFFKDGYMVVNISSLSVNEPEGVKDKDTEIGFSLDRTKNDGFSSYLDED
                     VNYCILKKKSMSSVTLLILDISGSGVKVRSPPEAGKQLPEIVFSKDEKVPSRSQEPAV
                     SSNPKDSKVQRTPDGSKAQRSTVDSKTIAEKFFSIHKNDGAVSFQFFFNISTSDQEGL
                     YSLYFHKCPSSKLRSGEQVSFSLNIDITEKNPDSYLSAGEIPLPKLYVSMALLFFLSG
                     TVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYI
                     THLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEG
                     TTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYV
                     LIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQL
                     SQEEDDLEMESVVTTSGVMENMKKVKKVSNGAVEPQGSWEGTA"
     exon            157..279
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            280..330
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            331..413
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            414..553
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            554..591
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            592..648
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            649..759
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            760..893
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            894..969
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1043
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1161
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1292
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1336
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1386
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1470
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1592
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..3950
                     /gene="Gpr107"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagaggaag cagctggtga tgctggaata aatatggccg tccgggtacc cctcggctgc
       61 acgggctcct tctgcccgcg gctgctacca ctgctggcat tgttggagct gctcgtcgac
      121 cccagcttgg gccgcgtcca tcacctggcg ctcaaagatg acgtgcggca caaagtccat
      181 ctcaacacct tcggcttctt caaggacggg tacatggtgg tcaacatcag cagcctctct
      241 gtgaacgagc ctgagggagt caaggacaaa gacactgaga ttggcttcag tcttgatcgg
      301 accaagaatg atggcttttc ttcttacctg gatgaagatg tgaattactg tattttaaaa
      361 aaaaagtcca tgtcttctgt cactctgctc atcttagaca tctccggaag tggagtcaag
      421 gtcagatccc caccagaagc tggcaagcag ttacccgaga ttgtcttcag caaggatgag
      481 aaagtcccga gtcggagcca ggagcctgct gtcagctcca accccaaaga cagcaaggtg
      541 cagagaaccc ctgatggttc caaggctcaa cgaagtacag tggattcaaa gactatagca
      601 gagaaattct tctcaattca taagaatgat ggggcagttt catttcagtt cttctttaac
      661 atcagcacca gtgaccagga aggcctctac agcctttact tccacaagtg cccaagcagc
      721 aagctgaggt ctggtgagca ggtctcattc agcctaaata ttgatatcac cgagaagaat
      781 cctgacagct acctgtctgc aggggaaatc cctctcccca agttatacgt ttccatggcc
      841 ttgttgttct tcctgtctgg gaccgtgtgg attcacatcc ttcgtaaacg aaggaatgat
      901 gtatttaaaa ttcactggtt gatggcggcc cttcctttca ccaagtctct ctccttggtg
      961 ttccatgcaa tcgactacca ctacatctcc tcgcagggct ttccgattga aggctgggct
     1021 gttgtgtact acataactca cctgctgaag ggtgcactgc tgttcatcac catcgccctc
     1081 attggcactg gctgggcctt catcaagcac atcctgtctg ataaggacaa gaagatcttc
     1141 atgattgtca ttccgctcca ggtactggcg aatgtggcct acatcatcat agagtctact
     1201 gaggagggca caactgagta tggcttgtgg aaggactctc tattcctggt ggatttgctg
     1261 tgctgcggcg ccatcctctt cccagtggtg tggtcaatca ggcatttaca agaagcctcg
     1321 gccacagatg gaaaagctgc cattaaccta gcaaagctga agcttttcag acattactac
     1381 gtcctgatcg tgtgctacat ctacttcacc aggatcatcg cctttcttct caagttcgct
     1441 gttcccttcc agtggaagtg gctctaccag ctgctggatg aaacagccac actggtgttc
     1501 tttgtcctga cggggtataa atttcgccca gcttcagata acccctacct gcagctctct
     1561 caggaagaag atgacctgga gatggagtct gtagtgacga cgtcaggagt aatggagaac
     1621 atgaagaagg tgaagaaagt gagcaatggt gctgtggagc cccagggcag ctgggaaggc
     1681 accgcgtgac agcgcagctg aggaccgcag gccgtcaatg aacctagctt atccatagcc
     1741 ctatcagtga gcacgcctgt tcctgacaga cgatggcatc tcccagcagc aacaccccgg
     1801 cgctcagcac catggccgag ccgagtgcta tggacacaca cttttgtact cttagggatc
     1861 tggattgagg tgggctacag gcagtgagga ctgccctcag tgagggcgga ggcttagagg
     1921 aggagtaaag actgtctgtc tgatttacct tgctaattgg gagcctgggt ctgtgcaggg
     1981 gagcccccag tggctgctac tcagaaaggc tgtgggtgtg gcacgggtct gccactcgct
     2041 ggtcacagtt ctgtggaggc tgggaggatg tgactcactg cttggcctag catttacgag
     2101 gctttgggtt caattcctag tgccagggtg gggggaaaag aagttacttt gggactagtc
     2161 aggtatctac caagggcaca gagaagagaa agagattgtc agcctttggg aacaagaaca
     2221 acagaaatga ttgaaattct tttaaatagc caataaaccc ctaggtggca gaagacacct
     2281 gtccagggtc actggccccc aggcaccact ctaaatgtcc ctgcccctga tgtgacctac
     2341 aacagtggtg ctagaggcca gagggaggga gggagggggc ctgttacatg gctggctgca
     2401 ggggagaaga gccttggctc tccagaagtg ttctccagtt ggctctcagg actccatccc
     2461 ctggctgcct gcccagagca gccgcctggc ttcctctcct tccacctgtg tcttctgatc
     2521 cgagaaaaca gttttcctga aggagcagcc gaggacagaa agggtagtct ctaaacaaac
     2581 acttaggtta agcatcttcc acagctcgca tgggccaggc aggacctctg agcctcagct
     2641 atagtccaag catgcgtgaa ggaagtgttt gagccactca tgctcagaga cctgaggcag
     2701 ccgggtctgc tcagagcttg gacagggaca ccagcggcac ctgcggaagg cctgtgaggg
     2761 gccacaggag accagctcag cacctcagag ctgctgcctg cccagaactg gcgggcgagt
     2821 tgcaccttca aggaacaggc acttccggga ggggggtgag ttactccacc tcccagtgca
     2881 gaagacaaag gtctggtctc cacaccacac cccaagtccc tgtcctgtgc caccagtgag
     2941 aagctgctgt ctgctgccct agcaggtccg tcactaccgc aggtgctcca tcttgagaaa
     3001 ggtcgacagg cctgaaggat ccacctaaag gacctttttc tcctgttttg tttgctttgt
     3061 ttatacttgt ttaaagtatg tggtgggaag ggagtgtcga ggagacaagg tgttaatgct
     3121 ttgtcttctg cacataagca ctcctccagc actgcagaag tgtgtccctg tggtgactct
     3181 aagccacagc tgtccctcag agggcgcgat ctttatggaa ggagcctcct ttcacttgct
     3241 gggttttaat aaggccactc tgacagagag cagagggagc tgtgtacaac ccagccacag
     3301 agctctctgg gtgcacagct gagcggctat gggagacagc ccgctccttc cagagcatgg
     3361 gtgcacaggc agggaggtgt gctacagcag cggccctccc aagtcctgcc ctgtgactgc
     3421 tgtaggtggg aagccaggca tgttgggggt tgtggtgggg aggggggatc agaagcctaa
     3481 catggggctg ggaagaactg gcctggtgcc caggctgtgg aaaggaaaac tcccagccct
     3541 cagcatgcac tgtaaggtgt ctgtctcatc tgcatcgctt gagagctggg agcccgcatt
     3601 cagcagtgtc cttgggtaga ggagtctgat tggcatccag ccgccccagt tcatgagctg
     3661 ccctctgcag ccttgagtct tagcctaccc agctccacaa ccgtgtttga gtggtgaagc
     3721 ccttgtgttg gaggggctga gcagaaatgg ggtgtacatt gcactgccac tgtggtatta
     3781 atagctctgt gttgtgtccc cacccccacc ccccatcttc tgcctgcgtg aggtatccat
     3841 acttgttttg agagtgctgt ggactggaag ctgtgggctg tgacatttaa taaagtgtgg
     3901 attttgttag ataattattt cttggacaac aggaacaagt gttcagctct
//
