LOCUS       NP_001101728             508 aa            linear   ROD 20-MAR-2023
DEFINITION  probable G-protein coupled receptor 101 [Rattus norvegicus].
ACCESSION   NP_001101728 XP_001053254 XP_229186
VERSION     NP_001101728.1
DBSOURCE    REFSEQ: accession NM_001108258.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 508)
  AUTHORS   Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li
            SS, Teasdale RD and Collins BM.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   2  (residues 1 to 508)
  AUTHORS   Nilaweera KN, Wilson D, Bell L, Mercer JG, Morgan PJ and Barrett P.
  TITLE     G protein-coupled receptor 101 mRNA expression in supraoptic and
            paraventricular nuclei in rat hypothalamus is altered by pregnancy
            and lactation
  JOURNAL   Brain Res 1193, 76-83 (2008)
   PUBMED   18187126
  REMARK    GeneRIF: Increased GPCR101 mRNA expression in supraoptic and
            paraventricular nuclei from late pregnancy to late lactation may
            reflect the functional importance of this receptor in the
            regulation of neurons of these nuclei during this period.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474019.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_229186.4, XP_001053254.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: CB727369.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760393, SAMEA5760433 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq36"
     Protein         1..508
                     /product="probable G-protein coupled receptor 101"
                     /calculated_mol_wt=56216
     Region          33..461
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          34..58
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          67..89
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          105..127
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          150..166
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          190..213
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          394..416
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          429..454
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..508
                     /gene="Gpr101"
                     /gene_synonym="RGD1564196"
                     /coded_by="NM_001108258.1:228..1754"
                     /db_xref="GeneID:317608"
                     /db_xref="RGD:1564196"
ORIGIN      
        1 mpssctnstq ennssrvclp lskmpisiah giirsvvlli ilgvafvgnv vlgyvlhrkp
       61 hllqvtnrfi fnllvtdllq valvapwvvs taipffwpln ihfctalvsl thlfafasvn
      121 tivvvsidry lsiihplsyp skmtnrrsyi llygtwiaaf lqstpplygw ghatfddrna
      181 fcsmiwgdsp aytvvsvvsf lviplgvmia cysvvfgaar rqqallykak shrfqvrvkd
      241 svvheneqga krdecqdene fedqdeggqe stsmldegam vaenssmktg agsldfcasi
      301 laamgseevs ngsmeglels teiqassaka ntdrrdvnqc niyvgeddve fgmdeihfne
      361 ddveamripe srppsrrnst snpplppcye ckaarvifii ifsyvlslgp ycflavlavw
      421 vdidsqvpqw vitiiiwlff lqccvhpyvy gymhksikke ikevlkkltc kkstsvddsh
      481 pelreteagt eggtegkaip shdsatsp
//
