LOCUS       NM_001109381            4034 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus G patch domain and KOW motifs (Gpkow), mRNA.
ACCESSION   NM_001109381 XM_001054977 XM_001055037 XM_001055091
VERSION     NM_001109381.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Zang,S., Lin,T.Y., Chen,X., Gencheva,M., Newo,A.N., Yang,L.,
            Rossi,D., Hu,J., Lin,S.B., Huang,A. and Lin,R.J.
  TITLE     GPKOW is essential for pre-mRNA splicing in vitro and suppresses
            splicing defect caused by dominant-negative DHX16 mutation in vivo
  JOURNAL   Biosci Rep 34 (6), e00163 (2014)
   PUBMED   25296192
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  AUTHORS   Aksaas,A.K., Larsen,A.C., Rogne,M., Rosendal,K., Kvissel,A.K. and
            Skalhegg,B.S.
  TITLE     G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear
            RNA-binding protein regulated by protein kinase A
  JOURNAL   J Mol Signal 6, 10 (2011)
   PUBMED   21880142
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001109381.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.62132.1,
                                           SRR26643429.58624.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-265               JAXUCZ010000021.1  17478034-17478298   c
            266-423             JAXUCZ010000021.1  17476757-17476914   c
            424-548             JAXUCZ010000021.1  17476529-17476653   c
            549-658             JAXUCZ010000021.1  17473360-17473469   c
            659-872             JAXUCZ010000021.1  17471886-17472099   c
            873-1005            JAXUCZ010000021.1  17468902-17469034   c
            1006-1144           JAXUCZ010000021.1  17468131-17468269   c
            1145-1268           JAXUCZ010000021.1  17467814-17467937   c
            1269-1338           JAXUCZ010000021.1  17467653-17467722   c
            1339-1424           JAXUCZ010000021.1  17466224-17466309   c
            1425-4034           JAXUCZ010000021.1  17463525-17466134   c
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..4034
                     /gene="Gpkow"
                     /note="G patch domain and KOW motifs"
                     /db_xref="GeneID:679890"
                     /db_xref="RGD:1583600"
     exon            1..265
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..1559
                     /gene="Gpkow"
                     /note="G patch domain and KOW motifs-containing protein"
                     /codon_start=1
                     /product="G-patch domain and KOW motifs-containing
                     protein"
                     /protein_id="NP_001102851.1"
                     /db_xref="GeneID:679890"
                     /db_xref="RGD:1583600"
                     /translation="MAGRESPPPAAASTAPISFGFTRTSVRRRLADLGDSEGQAPEKK
                     DFLATVEGRELQSVNPPEAPKELVIPLIQNGSRRQLLSKNPKPSETSTVLTSDGVLSQ
                     AVKELIEESKKSLEERENAGVDPTLTIPMIQKGCTPIGEGTYSEPQAETVPEEADYEA
                     VPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKGLGLGANLMETQALASTG
                     SHHPPRPDGDREKDKEGQPQGLMHGGAVVVLSGPYRGLYGKVEGLDPDNVRAMVRLAV
                     GNRVVNVSEYCLRPVSQQEFDSHTSKPGHVSKTSTEQQHRATGTASSVKALQNQEDSK
                     RRQKDSEKKRKHSPDRRDGPVPKTEKAAPRNKHWLHRDLRVRFIDKVHKGGRYYNTKM
                     TIEDVLSPGTCVCRTDEGRVLEGVKEGMLETLVPRGEGHRVMVVLGPHAGKVGLLLRR
                     DRAQSHAMVQLGRENQVVELHYDAICQYMGPGDSDED"
     exon            266..423
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            424..548
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            549..658
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            659..872
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1005
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1144
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1268
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1338
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1424
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..4034
                     /gene="Gpkow"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attctgggat agattctggc gttcctgggc ggcccttaag gtactagagt taaacttccc
       61 agcaggcaga gcgctcgcct gggactcgag ccaagatggc gggccgtgag agtccgccac
      121 cggctgccgc gtccacagct ccgatttctt tcggtttcac tcgcacatct gtccggaggc
      181 gactggcaga cctcggagac agcgaaggac aggccccaga gaagaaagat ttcttggcga
      241 ctgtggaagg gagggagctg cagagtgtga accctccaga agctccaaag gagctggtta
      301 tcccattgat ccagaatggc tctcgcaggc aactgctgtc caagaaccct aagccctcag
      361 aaacaagcac cgtgttgacg tcagatggtg tgttgtccca ggctgtgaag gaactcattg
      421 aggaatccaa gaagtctctg gaggagaggg agaatgcagg tgttgacccc acgctcacta
      481 tccccatgat ccagaaagga tgtactccca ttggggaagg aacatacagc gaacctcagg
      541 ctgagacagt gccggaagaa gccgactatg aggcagtgcc tgtggaggcc tatgggctgg
      601 ccatgttgcg gggcatgggc tggaaacctg gcaagggcat cggcaataca ttcagtcagg
      661 tagtgaagcc ccgagtcaac tctataaggc caaagggctt agggctgggt gccaacctga
      721 tggagactca ggccttggcc tccactggct ctcaccaccc accaagacca gatggggatc
      781 gtgagaagga taaggaaggc caacctcaag ggctgatgca tggaggagct gtggtggtcc
      841 tttctggccc ttaccggggc ctctatggga aggtagaagg cctagatcct gacaatgtac
      901 gagccatggt tcggctggca gtaggcaacc gcgttgtgaa tgttagtgag tattgcctgc
      961 ggcctgtttc ccagcaggag tttgatagcc acacgtcgaa gccaggccat gtgagcaaaa
     1021 cttccacaga gcagcagcac agagcaactg gaacagcctc atcagtgaag gccctacaga
     1081 atcaggaaga ctcaaagagg aggcagaagg attcagagaa gaagcggaaa cactctcctg
     1141 accgacggga tggacctgtg cccaagactg agaaagcggc gcctagaaac aagcactggt
     1201 tacacaggga cctacgtgtg cggttcattg acaaagtgca caagggtggc cgctattata
     1261 acaccaagat gacaattgaa gatgtcctga gcccaggtac ttgtgtgtgt cggacggatg
     1321 aaggccgagt tctagaaggt gtgaaagaag gcatgctgga gaccctggtt cccaggggag
     1381 agggccaccg cgtgatggtg gtactgggac cacatgctgg aaaggtggga cttcttctgc
     1441 gtcgggacag agcacagagt cacgctatgg tccagcttgg gagagagaat caggtggtgg
     1501 agctccacta tgatgccatc tgccagtaca tgggccccgg tgactcagat gaagactgac
     1561 acatggacca ttgcccgtca ctcaggctgt cactactttt gttacaattt ataacatgcc
     1621 agaggaagat gggaaataat tgtttgagat gcaaagatgg ggatgtgact agatagaaca
     1681 ggctatttac caaaatttag agcataataa aaaccatttt caatggtgaa aggttgaaat
     1741 caaaaccagt atgtgaactg taaatttggg tgggaactga gataacagaa gtagaaatac
     1801 ttcgtttctt aacctcattt ccctgctgaa ggtgcagggc aagttagatt acccactcaa
     1861 tacatagctc acccttggaa cttaagaact atgaagtcta tccccaaaca ctatcgaatc
     1921 tgcaatgcca catctcagaa caacttcctg agtttgggtc ttgaatggcc ttcaaaggcc
     1981 catatctttt ttttataaga tttattgtat gttgctgttg ttgttgttgt tgttgttgtt
     2041 gttgttgctt tatgagagag agagagagag agagagagag agagagagag agagactgtg
     2101 aatataaatg aatgctttca gagaccatga gtgttgagtt cccctagagt cgaagttata
     2161 ggcaattgca agctgcctag catgggtgct aggaaccaaa ctgaggtcct ttggaagcgc
     2221 agtaagcact cttaaccact gagctacctc cccagctcat atgccacatg gtaaaggatt
     2281 tgtgctcaag actgtactac tagcatatac ttttgacctt tgaaaaataa aggcctgggg
     2341 gagattactt aggtcatgac ttagaacctc taaaactgat ccaaataata cctttcctcc
     2401 ttataattta attacggctg gaagtttgtc agaggaaggg gaaagtaact cttattccca
     2461 ttgacaactc tagtaggaac atctgtttca tccttgatcc agggaagacc tccaggattg
     2521 tccccgagct gatgatgcac tgaagagaaa gggatacttc tgcccacgaa tatgatgggt
     2581 tagttccagt ttccaaagga gctagtcact ttagtccaga acactgctca ggttaaaggt
     2641 atttctgact tatgcagttt ctctgcttac cctaggtaca ttcttaaaaa agaaaaaaag
     2701 ggggttgggg atttaggtca gtggtagagc gcttgcctag caaacacaag gccctgggtt
     2761 cggtccccag ctccgaaaaa aaaaaaaggt tattgttgag aatcctgaac ctttttcctg
     2821 ttcaatggtt agagaagaaa agtcagagac ttagacacaa ttgtttctaa atcatctcta
     2881 aatcatatac atacagatgg atgatacttg acttagatct gggccacagg taaaaagtta
     2941 cctaacttgt cagactgtgg cacacactaa aaacactgaa aagaatcgaa acactgcaga
     3001 acaggatggt actggtaaat gtggctattg ctggagctca gtattggtac atttgcctag
     3061 catatgtaaa tccctgggtt ccacattagg gggcggggga ggaaattgct gtctctgttg
     3121 aacaaggcaa actgaactct ctggtcaaaa tgaacagaca gaaagatgtg agtcacaccg
     3181 agtgcagtgg cccatgtcag gaatctagca cttgagaagc tgagacagga aagtctgagc
     3241 ttcactgccc tttcatcaaa acctaaaagg aaatgtgcta agtgtagtag cacacacctt
     3301 tgatcctagc actcaggaga cagaagtagg cagacctcca taagtgcaaa gccagcctgg
     3361 tttacacaag ctccggtcca gccagaactc attggaagaa cctgtctcaa agaagaaata
     3421 ggaatgtgtg gcttttttcc ttcctcttgt cccttttatg tctctctctt acctaattgc
     3481 tacatctaag actttgatac tgtatcacat aagatagggg agagtggaca tcttgttact
     3541 gatttcagag aaaatgctca gtgtgtctat atataatata atgttggcta tagatttatt
     3601 gtatatagcc attattattt tgacatattt ccatgtattc caacagtttc cagagctttt
     3661 atcacaaaaa tatgttgaac tttgtaaatg ggttttcagc attcactgaa ctaattcatg
     3721 cttttctgtt cgtgagtttg tttatatgct gtattccatt tgctgattta tgtaagttga
     3781 aacacctttg ccttttggga atgatgcgta cttggtcata atgtgtaatc ttcctaatat
     3841 attcctagat tcagtttgta agcattttgt taggaatttt tttaacgtaa catttttatt
     3901 aactctgcag gaatttcaca ttatgcaccc tgatcacact tcccagtcct tccatgtcgt
     3961 cccccaccct actttgtgac ctccccacca aaacaagtta aaataaaaaa aataataact
     4021 aaaaattaga aaat
//
