LOCUS       NM_001107285            2491 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus glypican 5 (Gpc5), mRNA.
ACCESSION   NM_001107285 XM_001078143 XM_224489
VERSION     NM_001107285.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2491)
  AUTHORS   Williams,E.H., Pappano,W.N., Saunders,A.M., Kim,M.S., Leahy,D.J.
            and Beachy,P.A.
  TITLE     Dally-like core protein and its mammalian homologues mediate
            stimulatory and inhibitory effects on Hedgehog signal response
  JOURNAL   Proc Natl Acad Sci U S A 107 (13), 5869-5874 (2010)
   PUBMED   20231458
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Dec 3, 2009 this sequence version replaced NM_001107285.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on both rat and homologous mouse transcript
            alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.58405.1,
                                           SRR26643297.45933.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-163               JAXUCZ010000015.1  98646758-98646920
            164-325             JAXUCZ010000015.1  98676897-98677058
            326-1020            JAXUCZ010000015.1  98919532-98920226
            1021-1154           JAXUCZ010000015.1  98953596-98953729
            1155-1184           JAXUCZ010000015.1  98986778-98986807
            1185-1280           JAXUCZ010000015.1  98986808-98986903
            1281-1401           JAXUCZ010000015.1  99130133-99130253
            1402-1561           JAXUCZ010000015.1  99362447-99362606
            1562-2491           JAXUCZ010000015.1  100050356-100051285
FEATURES             Location/Qualifiers
     source          1..2491
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q23-q24"
     gene            1..2491
                     /gene="Gpc5"
                     /note="glypican 5"
                     /db_xref="GeneID:306157"
                     /db_xref="RGD:1308835"
     CDS             1..1719
                     /gene="Gpc5"
                     /codon_start=1
                     /product="glypican-5 precursor"
                     /protein_id="NP_001100755.2"
                     /db_xref="GeneID:306157"
                     /db_xref="RGD:1308835"
                     /translation="MDARTWRLGWRCLLLLALLGSTRSEGVESCEEVRKLFQWRLGGA
                     VKGLPEAPRAGPDLQVCLSKNPTCCTRKMEEQYQIAAQQDLQQVLQTSSSTLKLLISR
                     NAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASTQEFFTDVGLYLFGADVNPE
                     EFVNRFFDSLFPLVYNHLINPGVTDSSLQYSECIRTARQDVSPFGNIPKRVMGQMGRS
                     LLPGRTFLQALNLGIEVINTTDHIHFSKECSRALLKMQYCPHCQSLTLSKPCMGYCLN
                     VIRGCLAHMTDLNPHWHAYIRSLEELSDAMHGTYDVEHVLLNFHLLVNDAMLQAHLNA
                     QKLLDQVNKICGLPVRTATQSPRCTFDPSKERHGMKISPRNGEETLANRRKEFINSLR
                     LHRSFYGGLADQLCVNEWAAAEGRPCWNGEDIVKSYAQRVVGNGVKAQSANPEVRVRG
                     TDPVVNQIIDKLKHVIQLLQGRSPKPNKWELLHPGSGGGMLEQSSGDCDDEDGCGGSG
                     SGEVKRTLKITNWMPDSMNFSDVKQVHGADRGSTLDTTGAGCGSGTESMTLLLMGTLM
                     FLPWLW"
     exon            1..163
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            164..325
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            326..1020
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1154
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1280
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1401
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1561
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..2491
                     /gene="Gpc5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggatgctc gcacctggcg tctgggatgg cgctgtctcc ttctcctggc tcttcttgga
       61 tctacccgaa gcgagggcgt ggaaagctgc gaagaagttc ggaaactttt ccagtggagg
      121 cttgggggag ctgtcaaggg gctgccggag gcgccgcggg caggacctga tcttcaggtg
      181 tgcctatcca aaaacccaac gtgctgtacc aggaagatgg aggagcagta ccagattgcc
      241 gctcagcagg atttgcagca ggtgctacag acatccagct caacactaaa gttgctaata
      301 tctcggaatg cagctgcttt tcaagagacc ctggaaaccc tcatccgaca agcagagaat
      361 tacaccagta tccttttctg caacacctac cggaacatgg ccttggaggc tgctgcttcc
      421 actcaggagt ttttcaccga tgtgggactc tatttatttg gtgcggatgt taaccccgag
      481 gaatttgtaa acagattttt tgacagtctt ttccctctgg tctataacca tctcataaac
      541 cctggtgtga ctgacagttc tctgcaatac tcagaatgca tccgaacggc ccgccaggat
      601 gttagtccat ttggcaacat ccccaaaaga gtcatgggac agatggggag gtcactgctg
      661 cccggtcgca cattcctgca ggcgcttaat ctgggcattg aagtcatcaa caccacggac
      721 catatccact tctctaagga gtgcagtagg gccctcctga agatgcagta ctgtcctcac
      781 tgccagagcc tgacgctcag taagccctgt atggggtact gcctcaatgt catcaggggc
      841 tgtctagccc acatgacaga ccttaatcca cactggcatg cttatatccg ctccttggaa
      901 gagctgtcgg atgcgatgca cggaacctac gacgttgagc acgtgctcct gaacttccac
      961 ttacttgtta atgatgccat gctgcaggct cacctcaatg cgcagaagtt actggatcag
     1021 gtgaataaga tttgcggcct tccagtgaga acagcgacgc agagcccccg ctgtactttt
     1081 gatccaagca aagagaggca tgggatgaag atctctccaa ggaatggtga agagacactt
     1141 gccaacagaa gaaaagaatt catcaatagc cttaggctgc acaggtcctt ctatggtggc
     1201 ctggctgacc agctttgtgt taatgaatgg gctgcagctg aagggaggcc ctgctggaat
     1261 ggggaggaca tagtgaaaag ctatgctcag cgtgtggttg gaaatggcgt caaagcccag
     1321 tctgcaaatc ctgaagtcag agtcagagga actgatcctg tggtaaatca gataattgac
     1381 aaactgaagc atgtgatcca gctgttacag ggcagatcac ccaaacccaa caagtgggag
     1441 cttcttcatc cgggcagtgg tggcggcatg cttgagcaat ctagtggaga ttgtgatgac
     1501 gaagacggtt gtgggggatc aggaagcgga gaagtcaaga ggaccctaaa gatcacaaac
     1561 tggatgccag acagcatgaa cttcagtgac gtcaaacaag ttcatggagc agaccgtgga
     1621 agtactctgg atacaactgg tgcgggatgc gggtcaggaa ctgagtctat gacgctcctg
     1681 ctgatgggga cgctgatgtt tcttccctgg ctttggtaat ggagctcttc ttcaagacat
     1741 accctactgc agacttgact tatcccctat ctctttatgc ctggaaaaga agaactctta
     1801 aaataccgat ggaaattaca ggaaagtatg cgatagtaac ttcttagaag ccaatggaat
     1861 gtccacagca ttcctatcaa tcaagactct gatagtctgt ttcaaactct gtcttcttgg
     1921 catctaactt aaaacttctt aaattctaac actcaatcta aactgtgaaa actcagaagt
     1981 gacttttaat aagaaggctt cggtgtatct gtaattctgc tctgctcaat caaacccttt
     2041 cctttcagtg ttgtgaatgc tggcatttga gggtgtgttt gccaagcacg ggatacgata
     2101 agtagtattt cttaaagtac tgggaataaa aataacatta agtcaaagca cacaaaggca
     2161 agtattatgc atgcattctg ggagattctt tcatttttgc gagttaaatc aagaagttgc
     2221 tacaagtctg tgagctatac agtagattag cagggcgatt tcacataaat tcactgaagg
     2281 agcttggtaa tgtgttctcc cacgaaacct cctctactga gcttagtgac ttagagatgc
     2341 ccctgtgatg tccctttaac atttgaaatg cactgtcgta tcatggctct gttcctcttt
     2401 tgtcttttcc taaaacatct agctatgtca gaaaagcaca cttatctact ccaataaagg
     2461 tgttgattat ctgatgaaaa atgttaaaga a
//
