LOCUS       NP_001100755             572 aa            linear   ROD 03-APR-2024
DEFINITION  glypican-5 precursor [Rattus norvegicus].
ACCESSION   NP_001100755 XP_001078143 XP_224489
VERSION     NP_001100755.2
DBSOURCE    REFSEQ: accession NM_001107285.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 572)
  AUTHORS   Williams,E.H., Pappano,W.N., Saunders,A.M., Kim,M.S., Leahy,D.J.
            and Beachy,P.A.
  TITLE     Dally-like core protein and its mammalian homologues mediate
            stimulatory and inhibitory effects on Hedgehog signal response
  JOURNAL   Proc Natl Acad Sci U S A 107 (13), 5869-5874 (2010)
   PUBMED   20231458
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Dec 3, 2009 this sequence version replaced NP_001100755.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on both rat and homologous mouse transcript
            alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.58405.1,
                                           SRR26643297.45933.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q23-q24"
     Protein         1..572
                     /product="glypican-5 precursor"
                     /calculated_mol_wt=60961
     sig_peptide     1..24
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2789
     Region          20..569
                     /region_name="Glypican"
                     /note="pfam01153"
                     /db_xref="CDD:460084"
     CDS             1..572
                     /gene="Gpc5"
                     /coded_by="NM_001107285.2:1..1719"
                     /db_xref="GeneID:306157"
                     /db_xref="RGD:1308835"
ORIGIN      
        1 mdartwrlgw rcllllallg strsegvesc eevrklfqwr lggavkglpe apragpdlqv
       61 clsknptcct rkmeeqyqia aqqdlqqvlq tssstlklli srnaaafqet letlirqaen
      121 ytsilfcnty rnmaleaaas tqefftdvgl ylfgadvnpe efvnrffdsl fplvynhlin
      181 pgvtdsslqy secirtarqd vspfgnipkr vmgqmgrsll pgrtflqaln lgievinttd
      241 hihfskecsr allkmqycph cqsltlskpc mgyclnvirg clahmtdlnp hwhayirsle
      301 elsdamhgty dvehvllnfh llvndamlqa hlnaqklldq vnkicglpvr tatqsprctf
      361 dpskerhgmk isprngeetl anrrkefins lrlhrsfygg ladqlcvnew aaaegrpcwn
      421 gedivksyaq rvvgngvkaq sanpevrvrg tdpvvnqiid klkhviqllq grspkpnkwe
      481 llhpgsgggm leqssgdcdd edgcggsgsg evkrtlkitn wmpdsmnfsd vkqvhgadrg
      541 stldttgagc gsgtesmtll lmgtlmflpw lw
//
