LOCUS       NM_001106410            3461 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus GC-rich promoter binding protein 1 (Gpbp1),
            transcript variant 1, mRNA.
ACCESSION   NM_001106410 XM_001066754 XM_006231921 XM_215485
VERSION     NM_001106410.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3461)
  AUTHORS   denDekker,A.D., Xu,X., Vaughn,M.D., Puckett,A.H., Gardner,L.L.,
            Lambring,C.J., Deschenes,L. and Samuelson,D.J.
  TITLE     Rat Mcs1b is concordant to the genome-wide association-identified
            breast cancer risk locus at human 5q11.2 and MIER3 is a candidate
            cancer susceptibility gene
  JOURNAL   Cancer Res 72 (22), 6002-6012 (2012)
   PUBMED   22993404
REFERENCE   2  (bases 1 to 3461)
  AUTHORS   Hsu,L.C., Liu,S., Abedinpour,F., Beech,R.D., Lahti,J.M., Kidd,V.J.,
            Greenspan,J.A. and Yeung,C.Y.
  TITLE     The murine G+C-rich promoter binding protein mGPBP is required for
            promoter-specific transcription
  JOURNAL   Mol Cell Biol 23 (23), 8773-8785 (2003)
   PUBMED   14612417
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Jun 27, 2022 this sequence version replaced
            XM_006231921.2, NM_001106410.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ211661.1, SRR26643284.2575.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               JAXUCZ010000002.1  44824129-44824281   c
            154-1098            JAXUCZ010000002.1  44821991-44822935   c
            1099-1218           JAXUCZ010000002.1  44800978-44801097   c
            1219-1342           JAXUCZ010000002.1  44787257-44787380   c
            1343-1566           JAXUCZ010000002.1  44786910-44787133   c
            1567-1633           JAXUCZ010000002.1  44782548-44782614   c
            1634-1693           JAXUCZ010000002.1  44781514-44781573   c
            1694-1878           JAXUCZ010000002.1  44774503-44774687   c
            1879-2019           JAXUCZ010000002.1  44773264-44773404   c
            2020-2187           JAXUCZ010000002.1  44772141-44772308   c
            2188-2375           JAXUCZ010000002.1  44770551-44770738   c
            2376-2478           JAXUCZ010000002.1  44767395-44767497   c
            2479-3461           JAXUCZ010000002.1  44756861-44757843   c
FEATURES             Location/Qualifiers
     source          1..3461
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..3461
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /note="GC-rich promoter binding protein 1"
                     /db_xref="GeneID:294734"
                     /db_xref="RGD:1305492"
     exon            1..153
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            154..1098
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1218
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     CDS             1156..2637
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /note="isoform 1 is encoded by transcript variant 1;
                     vasculin"
                     /codon_start=1
                     /product="vasculin isoform 1"
                     /protein_id="NP_001099880.1"
                     /db_xref="GeneID:294734"
                     /db_xref="RGD:1305492"
                     /translation="MAQHDFAPAWLNFPTPPSSTKSSLNFEKHSENFSWTENRYDVSR
                     RRHNSSDGFDSGIGRPNGGNFGRKEKNGWRTHGRNGTENINHRGGYHGGNSRSRSSIF
                     HSGKSQGLHENNIPDNETGRKEDKRERRQFEAEDFPSLNPEYEREPNQNKSLAAGVWG
                     LHAQTHTYPTKKISQAPLLEYPPNPKSRTPRMLVIKKGNTKDLQLSGFPVAGNLQSQP
                     VKNGTGPSVYKGLVPKPAVPPTKPTQWKSQTKENKVGTSFPHESTYGVGNFNTFKSTA
                     KNISPSTNSVKECNRSNSSSPVDKLNQQPRLTKLTRMRSDKKSEFLKALKRDRVEEEH
                     EDESHAGSEKDDDSFNLHNSNSTHQERDINRNFDENEIPQENGNASVISQQIIRSSTF
                     PQTDVLSSSLEAEHRLLKEMGWQEDSENDETCAPLTEDEMREFQVISEQLQKNGLRKN
                     GILKNGLICDFKFGPWKNSTFKPTIENDDTETSSSDTSDDDDV"
     exon            1219..1342
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1566
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1633
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..1693
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1878
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2019
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2187
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            2188..2375
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            2376..2478
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
     exon            2479..3461
                     /gene="Gpbp1"
                     /gene_synonym="RGD1305492"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgcggatc gggtcggcgc cattttggga ctgagactgg ttgtggggga gggaaaagcg
       61 gcaaaagggg attattcaaa gtaccgaaaa cctcctcccg ggatcgagcg cagcggcacc
      121 cccaggccag gggcacctct ggtggggcag aaggtgactg agtttggcag atatgaagat
      181 catcatctag gttttgttta aaggccccgg atatttcaag tggccatttt ggaattacag
      241 tttgtttttg tttggggtaa ttttgcccca gaagtttatt aaaattggca agaatcatct
      301 ctgaagtgaa tgatagtagt gaacaacgag ctacttaaaa gacccagcca tttcttcagt
      361 attttggttc aaacggatta tataagtggt taaagtattt cgtctggtgt taattttgtc
      421 tcttccccct ctcctgttgg tgttcttcag ccaaaactgt aagatatgtt tgatttgtgt
      481 actgagtagt ttcagcagtt tcaaattact gtttaaatat tgctgaagtt ttgtggcagt
      541 tctttttacc tttattaaaa gttttagtaa tttttgactt cagctctttt catattacaa
      601 tgggacagct tttctaaatg aagacattga aagaatacag agtttttttc ttcttatctt
      661 ttatttactt gggaatgtaa gatgttccag ttccacagca gcatggtagt gttgagatag
      721 ctctttgttg tctgtatacg ctgatgttta gacgtaatct tcagatgtga aatttttctt
      781 tttgtttctg ctttttggca cataaattgg atatttcatc tggattggat aagtacaaca
      841 gtgacaaata catggaatag taaagaagac cttgctcttg aatccaagga acttggctaa
      901 ttctggatct agccatatga aaacttcaaa ataaatatgg gtagctgact tcaagtaact
      961 ctatgtcaaa tagtcatagg ttaagtatct tcaaagaact tggatatttc agaggataca
     1021 aaataaaaaa acaaactgga aaacataaag cttatagaga aaaaatcaac accttcctgt
     1081 gcagtcccct tggaatttgg acttgccatg aggtgttgaa gccttgtttc actgagttgg
     1141 agagactgga cctaaatggc gcagcatgac tttgctccag cctggcttaa ttttcctact
     1201 cctccatcat caacaaagtc atcattgaat tttgagaagc attctgaaaa tttttcatgg
     1261 acagaaaatc gttatgatgt gagtcgtcga cgacacaatt cttcagatgg ctttgattct
     1321 ggtattggac gtcctaatgg aggtaatttt gggaggaaag aaaaaaatgg atggcgtacg
     1381 catggcagaa atggtacaga aaacataaat catcgagggg gataccatgg tggaaattcc
     1441 cgttctcgta gcagtatttt ccattctgga aaaagccaag gactacatga aaacaacatc
     1501 cctgacaatg aaactgggag gaaagaagac aaaagagaac gcagacagtt tgaggctgag
     1561 gattttccat ctttaaatcc tgaatatgag agagaaccaa atcagaataa atctttagct
     1621 gcgggcgtat ggggcctaca cgcccagaca cacacatacc caaccaaaaa aatctcccaa
     1681 gctcctctct tagaatatcc cccgaatcct aaatctagaa ctccaagaat gctggtcatt
     1741 aagaaaggta atacaaaaga cttacagcta tctggattcc cagtagcagg aaacctccag
     1801 tcacaaccag ttaagaatgg aactggtccg agtgtttata aaggcttagt ccccaaacct
     1861 gctgttccac ctacaaaacc tacacaatgg aaaagccaaa ctaaagaaaa caaagttgga
     1921 acttcttttc ctcatgaatc tacatatggt gttggcaact ttaatacttt taagtcaacg
     1981 gccaagaata ttagcccatc aacaaattca gtgaaagagt gtaatcgttc aaattcttct
     2041 tcgcctgttg acaaacttaa tcagcagcct cgtttaacta aactgacacg aatgcgcagt
     2101 gataaaaaaa gtgaattttt gaaagcattg aaaagggaca gagtagaaga ggagcatgaa
     2161 gatgaaagcc atgctggctc agagaaggat gacgactcat ttaatttgca taacagcaat
     2221 agtactcacc aagaaagaga tataaacaga aactttgatg aaaatgaaat cccacaggag
     2281 aacggcaatg cctcggtgat ttctcaacag atcattcgtt cttcgacttt tccacaaact
     2341 gatgttcttt ccagttcact tgaggcagaa cacagattat taaaagagat gggctggcag
     2401 gaagacagtg aaaatgatga aacatgtgct cccttaactg aggatgaaat gagagaattc
     2461 caagttatta gtgaacagtt acagaagaat ggtctgagaa aaaatggtat tttgaaaaac
     2521 ggcctgatct gtgacttcaa gtttggaccc tggaaaaaca gcactttcaa acccacaatt
     2581 gagaatgatg acacagagac aagtagcagt gacacatcag atgatgacga tgtgtgaagg
     2641 atttcctcac agctttagaa attttagtgt gatacatctc tcatgcagtt tggggtgaat
     2701 tgtaaaaatg aagaactata atttatgtag tgaacctacc ccattagaag atgatttttt
     2761 tgggggactt caatatgaag aaaaccaaga atgttgtgtt gggctgtgtt gaacattatt
     2821 tctttgtaaa tgaatgttgt agaaatgagg actttggttg atccaacatt gactttcttc
     2881 atcactgcag catttctctt gactagcaat gtgacgatgt aacaaatgag attttctcat
     2941 ttaataataa aaaattgtgt aatgttttgc aaagcttctg tcttaaaatg ttcaggtctt
     3001 aaggtacaag gcagcttcca gttttgcttg cagagtcctc tctttttcca acagtggaaa
     3061 tcttcaactc tactttgtgc acctcctcac cccacttccc cctaaaacaa agcaacagca
     3121 aaaaggaaaa tgtagcatgt tggctaaaac tggagcaaag tgcactaaaa cattaacttc
     3181 ttgaactcaa ctcttgtact aagcaagtca cctttcagaa caaatttctc tttagtcttt
     3241 cgtagtgcag tgagtgcgag agaggagacg tgccgggcgt tcttccaagc tttaggaggt
     3301 gcttgtccag agctttattt ggtatactgt cagatcagga ttttcagagg tgattggaaa
     3361 agttgtggga aaacttattt tgataaatta ttacacatgc agaaaacctg atcactgact
     3421 ggatctgtcc acaacatgga aaataaactg gattttcaga a
//
