LOCUS       NM_001168529            2617 bp    mRNA    linear   ROD 14-AUG-2024
DEFINITION  Rattus norvegicus glycerol-3-phosphate acyltransferase 2,
            mitochondrial (Gpat2), mRNA; nuclear gene for mitochondrial
            product.
ACCESSION   NM_001168529 XM_001078526 XM_238283
VERSION     NM_001168529.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2617)
  AUTHORS   Shiromoto,Y., Kuramochi-Miyagawa,S., Daiba,A., Chuma,S.,
            Katanaya,A., Katsumata,A., Nishimura,K., Ohtaka,M., Nakanishi,M.,
            Nakamura,T., Yoshinaga,K., Asada,N., Nakamura,S., Yasunaga,T.,
            Kojima-Kita,K., Itou,D., Kimura,T. and Nakano,T.
  TITLE     GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis
            in germline stem cells
  JOURNAL   RNA 19 (6), 803-810 (2013)
   PUBMED   23611983
REFERENCE   2  (bases 1 to 2617)
  AUTHORS   Cattaneo,E.R., Pellon-Maison,M., Rabassa,M.E., Lacunza,E.,
            Coleman,R.A. and Gonzalez-Baro,M.R.
  TITLE     Glycerol-3-phosphate acyltransferase-2 is expressed in spermatic
            germ cells and incorporates arachidonic acid into triacylglycerols
  JOURNAL   PLoS One 7 (8), e42986 (2012)
   PUBMED   22905194
  REMARK    GeneRIF: GPAT2 expression is linked to arachidonoyl-CoA
            incorporation into TAG in spermatogenic germ cells
REFERENCE   3  (bases 1 to 2617)
  AUTHORS   Chen,Y.Q., Kuo,M.S., Li,S., Bui,H.H., Peake,D.A., Sanders,P.E.,
            Thibodeaux,S.J., Chu,S., Qian,Y.W., Zhao,Y., Bredt,D.S.,
            Moller,D.E., Konrad,R.J., Beigneux,A.P., Young,S.G. and Cao,G.
  TITLE     AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase
  JOURNAL   J Biol Chem 283 (15), 10048-10057 (2008)
   PUBMED   18238778
REFERENCE   4  (bases 1 to 2617)
  AUTHORS   Wang,S., Lee,D.P., Gong,N., Schwerbrock,N.M., Mashek,D.G.,
            Gonzalez-Baro,M.R., Stapleton,C., Li,L.O., Lewin,T.M. and
            Coleman,R.A.
  TITLE     Cloning and functional characterization of a novel mitochondrial
            N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase
            (GPAT2)
  JOURNAL   Arch Biochem Biophys 465 (2), 347-358 (2007)
   PUBMED   17689486
REFERENCE   5  (bases 1 to 2617)
  AUTHORS   Lewin,T.M., Schwerbrock,N.M., Lee,D.P. and Coleman,R.A.
  TITLE     Identification of a new glycerol-3-phosphate acyltransferase
            isoenzyme, mtGPAT2, in mitochondria
  JOURNAL   J Biol Chem 279 (14), 13488-13495 (2004)
   PUBMED   14724270
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before Dec 12, 2009 this sequence version replaced
            XM_238283.4, XM_001078526.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.962635.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000003.1  135101802-135101929
            129-242             JAXUCZ010000003.1  135102052-135102165
            243-316             JAXUCZ010000003.1  135102736-135102809
            317-421             JAXUCZ010000003.1  135103083-135103187
            422-550             JAXUCZ010000003.1  135103391-135103519
            551-650             JAXUCZ010000003.1  135105193-135105292
            651-784             JAXUCZ010000003.1  135105591-135105724
            785-884             JAXUCZ010000003.1  135105973-135106072
            885-1097            JAXUCZ010000003.1  135106165-135106377
            1098-1220           JAXUCZ010000003.1  135106662-135106784
            1221-1303           JAXUCZ010000003.1  135106956-135107038
            1304-1422           JAXUCZ010000003.1  135107279-135107397
            1423-1493           JAXUCZ010000003.1  135107870-135107940
            1494-1752           JAXUCZ010000003.1  135108012-135108270
            1753-1901           JAXUCZ010000003.1  135108352-135108500
            1902-1979           JAXUCZ010000003.1  135108655-135108732
            1980-2111           JAXUCZ010000003.1  135109041-135109172
            2112-2232           JAXUCZ010000003.1  135109269-135109389
            2233-2298           JAXUCZ010000003.1  135109475-135109540
            2299-2354           JAXUCZ010000003.1  135109743-135109798
            2355-2617           JAXUCZ010000003.1  135110093-135110355
FEATURES             Location/Qualifiers
     source          1..2617
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..2617
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /note="glycerol-3-phosphate acyltransferase 2,
                     mitochondrial"
                     /db_xref="GeneID:296130"
                     /db_xref="RGD:1304904"
     exon            1..128
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..2471
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /EC_number="2.3.1.51"
                     /EC_number="2.3.1.15"
                     /note="1-acylglycerol-3-phosphate O-acyltransferase GPAT2"
                     /codon_start=1
                     /product="glycerol-3-phosphate acyltransferase 2,
                     mitochondrial"
                     /protein_id="NP_001162001.1"
                     /db_xref="GeneID:296130"
                     /db_xref="RGD:1304904"
                     /translation="METMLKSNPQMQQRNNHSGQETSLWSSGFGMKMEAITPFLGKYR
                     PFMGRCCQTCTPKSWESLFHRSIMDLGFCNVILVKEENTRFRGWLVRRLCYFLWSLEQ
                     HIPTSSDASQMIMENTGVQNILLGKVPGAAGEGQAPDLVKKEVQRILGHIQTTPRPFL
                     LRLFSWALLWFLNRLFLNVQLHKGQMKMVHKAAQEGSPLVFLSTHKSLLDGFLLPFVL
                     FSQGLGVLRVALDSRTCSPALRALLRKLGGLFLPPEANLSLDSSEGILARAVVRATVE
                     QLLTSGQPLLIFLEEAPGYPGPRLSALGQAWLGLVVQAVQAGIVPDATLVPVATAYDL
                     VPDAPCNMTHDLAPLGLWTGALAIFRRLCNCWGCNRRVCVRVHLAQPFSLQEYTINAR
                     SCWGSRQTLEHLLQPIVLGECSVVPDTEKEQEWTPPTSLLLALKEEDQLLVRRLSRHV
                     LSASVASSAVMSTAIMATLLLLKHQKGVVLSQLLGEFSWLTEETLLRGFDVGFSGQLR
                     CLAQHTLSLLRAHVVLLRVHQGDLVVVPRPGPGLTHLARLSMELLPTFLSEAVGACAV
                     RGLLAGRVPPEGPWELQGIELLSQNELYRQILLLLHLLPQDLLLPQPCQSSYCYCQEV
                     LDRLIQCGLLVAEETPGSRPACDTGRQHLSAKLLWKPSGDFTDSESDDFEEPGGRCFR
                     LSQQSRCPDFFLFLCRLLSPILKAFAQAATFLHLGQLPDSEVGYSEKLLQFLQACAQE
                     EGIFECADPNLAISAIWTFKDLGVLQQIPSPTGPQLHLSPTFASRDNQDKLEQFIRQF
                     ICS"
     exon            129..242
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            243..316
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            317..421
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            422..550
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            551..650
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            651..784
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            785..884
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1097
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1220
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1303
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1422
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1493
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1752
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1901
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..1979
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2111
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2232
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            2233..2298
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2354
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..2617
                     /gene="Gpat2"
                     /gene_synonym="RGD1304904"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttctctagg tcaggtttgt gtggagagag gcacagtgct tccttccttg atctcacaga
       61 ccttcatgga gaccatgttg aagtccaacc ctcaaatgca gcagaggaat aaccacagtg
      121 gtcaagagac cagcctttgg tcctcaggct ttgggatgaa gatggaggcc atcactccat
      181 tcctggggaa gtatcgcccc tttatgggtc gatgctgcca gacctgtacc cctaagagct
      241 gggagtccct cttccacaga agcataatgg atctgggctt ctgcaatgtg atccttgtga
      301 aggaggagaa taccaggttt cggggctggc tggttcgcag gctctgctat ttcctatggt
      361 ccctggagca gcacataccc accagctctg atgcctccca gatgatcatg gaaaacactg
      421 gggtgcagaa catcctcttg gggaaggttc caggagcggc tggagaaggc caggcacctg
      481 acctagtgaa gaaagaggta cagcgcatcc tgggccacat tcagaccaca ccccgtccct
      541 tcttgcttag gctgttcagc tgggcactgc tgtggttcct gaaccgcctc ttcctgaacg
      601 ttcaacttca caagggacag atgaagatgg tccacaaggc tgcccaggag ggctctccac
      661 ttgtcttcct ttctacacac aagtccctct tggatgggtt cctgctgcct tttgtactgt
      721 tctcccaagg gctcggtgtg ctccgtgtgg ccttggactc ccgtacttgt tcccctgctc
      781 tcagagctct actgaggaaa cttggggggc ttttcctgcc cccagaggcc aacctctcat
      841 tggacagctc agagggcatc cttgcaaggg ctgtggtccg tgcaacggtg gagcagctgc
      901 ttactagtgg tcagcccctg ctcatcttcc tggaagaggc ccctgggtac ccagggccca
      961 ggctttctgc cctgggccag gcctggctag gactggtagt ccaggcggtc caggcaggca
     1021 tcgtcccaga tgccacactg gtaccagttg ccactgccta tgatctggtt ccagatgcac
     1081 catgtaacat gactcatgac ctggcccccc tggggctatg gacaggagcc ttggccatct
     1141 ttcggcgact gtgcaactgc tggggctgta accgtagagt ctgtgtccgg gtgcaccttg
     1201 cccagccatt ttccctccag gaatatacca tcaatgctcg aagttgctgg ggtagcaggc
     1261 agaccctgga acacttgttg cagcccattg tgctaggtga atgtagtgtt gttccagaca
     1321 ctgagaaaga gcaggagtgg accccaccaa ctagcctcct cctggccctc aaagaagagg
     1381 accagctcct ggtcagaaga ctgagccggc atgttctgag tgccagtgtg gccagctcag
     1441 cagtgatgag cacggccatc atggcaacac tgttgctgct gaagcaccaa aagggtgtgg
     1501 tcctgtcaca gctcctgggg gaattctcct ggctgacaga ggagacactg ctccgaggtt
     1561 ttgatgtggg cttctcaggg cagctgcggt gcctggccca acatacgctg agcctcttga
     1621 gggcacatgt ggttctgctg cgtgtccacc aaggggactt ggtggtggtg ccacggcctg
     1681 gcccaggcct cacacatctg gcacgcttga gtatggaatt gctgcccacc ttcctgagtg
     1741 aggctgtggg tgcctgtgcg gtgagggggt tgctggcggg cagagtacca cctgaggggc
     1801 cctgggagct gcagggcata gagctgctga gtcagaatga actgtaccgc cagatcctac
     1861 tgctgctgca cctgctacct caagacctgt tgctgcccca gccctgccag tcttcctact
     1921 gctactgtca ggaggtgctg gaccggctca tccagtgcgg gctcctggtt gcagaggaga
     1981 ccccaggctc ccggccagcc tgtgacacag gaagacagca tctgagtgca aagctgctgt
     2041 ggaaaccaag tggagacttt actgacagtg agagtgatga cttcgaggag ccagggggcc
     2101 gctgcttcag gcttagccag cagtctcgct gccctgactt cttcctcttc ctctgccgcc
     2161 tgctcagtcc catactcaag gcctttgcac aggcagccac cttcctccac ttggggcagc
     2221 tgccagattc agaggtgggc tactcagaga agttgttgca gtttttacag gcctgtgccc
     2281 aggaagaagg gatctttgag tgtgcagacc caaatctcgc tatcagtgca atctggacat
     2341 tcaaagacct gggggtactg cagcagatac ccagccctac aggaccccag ctccacctgt
     2401 cacctacatt tgccagccgg gacaatcagg acaagctgga acaattcatc cgacagttca
     2461 tctgcagtta gaaccagaga gtggaacttg atgggacttg ttagcctaga actcaagtgt
     2521 gtgtattctg gtcaggacac agctaacctg aacttacaaa acccgtgttt gcgcatcatt
     2581 tagtgtaata aatagactag gttagtttct tccctaa
//
