LOCUS       NM_001031825             845 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus glycoprotein IX (platelet) (Gp9), mRNA.
ACCESSION   NM_001031825 XM_578358
VERSION     NM_001031825.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Boeckelmann,D., Hengartner,H., Greinacher,A., Nowak-Gottl,U.,
            Sachs,U.J., Peter,K., Sandrock-Lang,K. and Zieger,B.
  TITLE     Patients with Bernard-Soulier syndrome and different severity of
            the bleeding phenotype
  JOURNAL   Blood Cells Mol Dis 67, 69-74 (2017)
   PUBMED   28131619
REFERENCE   2  (bases 1 to 845)
  AUTHORS   He,Y., Zhao,Y.X., Zhu,M.Q., Wu,Q. and Ruan,C.G.
  TITLE     Detection of autoantibodies against platelet glycoproteins in
            patients with immune thrombocytopenic purpura by flow cytometric
            immunobead array
  JOURNAL   Clin Chim Acta 415, 176-180 (2013)
   PUBMED   23103637
REFERENCE   3  (bases 1 to 845)
  AUTHORS   Tsuji,A.B., Sugyo,A., Ogiu,T., Sagara,M., Kimura,T., Ishikawa,A.,
            Sudo,H., Ohtsuki,M., Aburatani,H., Imai,T. and Harada,Y.N.
  TITLE     Fine mapping of radiation susceptibility and gene expression
            analysis of LEC congenic rat lines
  JOURNAL   Genomics 86 (3), 271-279 (2005)
   PUBMED   15978772
REFERENCE   4  (bases 1 to 845)
  AUTHORS   Berndt,M.C., Shen,Y., Dopheide,S.M., Gardiner,E.E. and Andrews,R.K.
  TITLE     The vascular biology of the glycoprotein Ib-IX-V complex
  JOURNAL   Thromb Haemost 86 (1), 178-188 (2001)
   PUBMED   11487006
  REMARK    Review article
REFERENCE   5  (bases 1 to 845)
  AUTHORS   Noda,M., Fujimura,K., Takafuta,T., Shimomura,T., Fujii,T.,
            Katsutani,S., Fujimoto,T., Kuramoto,A., Yamazaki,T., Mochizuki,T.,
            Matsuzaki,M. and Sano,M.
  TITLE     A point mutation in glycoprotein IX coding sequence (Cys73 (TGT) to
            Tyr(TAT)) causes impaired surface expression of GPIb/IX/V complex
            in two families with Bernard-Soulier syndrome
  JOURNAL   Thromb Haemost 76 (6), 874-878 (1996)
   PUBMED   8972003
REFERENCE   6  (bases 1 to 845)
  AUTHORS   Wright,S.D., Michaelides,K., Johnson,D.J., West,N.C. and
            Tuddenham,E.G.
  TITLE     Double heterozygosity for mutations in the platelet glycoprotein IX
            gene in three siblings with Bernard-Soulier syndrome
  JOURNAL   Blood 81 (9), 2339-2347 (1993)
   PUBMED   8481514
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Oct 20, 2022 this sequence version replaced NM_001031825.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB158423.1, AB158424.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680412, SAMN06680413
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                JAXUCZ010000004.1  121792842-121792904
            64-845              JAXUCZ010000004.1  121793671-121794452
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..845
                     /gene="Gp9"
                     /note="glycoprotein IX (platelet)"
                     /db_xref="GeneID:502858"
                     /db_xref="RGD:1561601"
     exon            1..63
                     /gene="Gp9"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..609
                     /gene="Gp9"
                     /note="glycoprotein 9 (platelet); platelet glycoprotein
                     IX"
                     /codon_start=1
                     /product="platelet glycoprotein IX precursor"
                     /protein_id="NP_001026995.1"
                     /db_xref="GeneID:502858"
                     /db_xref="RGD:1561601"
                     /translation="MAPAQASQPICWIPTWGLLLLLWPVTTATQDCPRPCTCQSLETM
                     GLKVNCEGRGLTALPVLPANTRQLLLTNNSLRSVPPGAFDHMPQLWELKVAHNPWHCD
                     CSLTYLRLWLEDHMPEALSHVYCASPDLATQRPLGQLTGYELGNCGWKLPPSWAYSGI
                     WWDVSLVAVAVLGLILLAGLLNTFTESRN"
     exon            64..845
                     /gene="Gp9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagcttgca cacacaccac caccgctgcc ttgaccagga tggcaccagc ccaggcctca
       61 cagcccatct gctggatacc tacctggggg ctcctgttgc tgctctggcc tgtgaccaca
      121 gctactcagg attgccccag accctgtacc tgccagtcct tggaaaccat ggggttaaag
      181 gtaaactgtg aggggcgagg cctcacagcc ctgcctgtgc tgccagctaa cactcgccag
      241 ctcctgctga ccaacaacag cctacgttca gtgccacctg gtgcctttga ccacatgcct
      301 cagctgtggg aacttaaggt ggcacacaac ccctggcact gcgactgcag cctcacctac
      361 ctacgcctct ggctggagga ccacatgccc gaggccctgt cacatgtgta ctgtgccagc
      421 ccggacttgg ctacccagcg cccactgggc cagctcacag gctatgagct aggtaactgt
      481 ggctggaagc tgccaccatc ctgggcctat tcagggatct ggtgggatgt gtcactggtg
      541 gctgtggctg tgctaggcct gattctgctg gctggtctac tgaacacatt tacagagtcc
      601 cggaactgaa cctagcccca aaaccaggga gagcccagac ctaagccagg tccccagaag
      661 catcagcccc agtcagccca tgctatcaaa agcccacacg gagtgggctg aggccacctc
      721 atgggtaaag gcacttgctg cccagtctaa agacctgggt tggatcctca gaagagaatg
      781 gaatctcacc tcctcagcct tgccatgccc acacgacaaa taaataaatg taattttaaa
      841 agaca
//
