LOCUS       NM_012795               2215 bp    mRNA    linear   ROD 07-APR-2024
DEFINITION  Rattus norvegicus glycoprotein V (platelet) (Gp5), mRNA.
ACCESSION   NM_012795
VERSION     NM_012795.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2215)
  AUTHORS   Moog,S., Mangin,P., Lenain,N., Strassel,C., Ravanat,C.,
            Schuhler,S., Freund,M., Santer,M., Kahn,M., Nieswandt,B.,
            Gachet,C., Cazenave,J.P. and Lanza,F.
  TITLE     Platelet glycoprotein V binds to collagen and participates in
            platelet adhesion and aggregation
  JOURNAL   Blood 98 (4), 1038-1046 (2001)
   PUBMED   11493449
REFERENCE   2  (bases 1 to 2215)
  AUTHORS   Ni,H., Ramakrishnan,V., Ruggeri,Z.M., Papalia,J.M., Phillips,D.R.
            and Wagner,D.D.
  TITLE     Increased thrombogenesis and embolus formation in mice lacking
            glycoprotein V
  JOURNAL   Blood 98 (2), 368-373 (2001)
   PUBMED   11435305
REFERENCE   3  (bases 1 to 2215)
  AUTHORS   Berndt,M.C., Shen,Y., Dopheide,S.M., Gardiner,E.E. and Andrews,R.K.
  TITLE     The vascular biology of the glycoprotein Ib-IX-V complex
  JOURNAL   Thromb Haemost 86 (1), 178-188 (2001)
   PUBMED   11487006
  REMARK    Review article
REFERENCE   4  (bases 1 to 2215)
  AUTHORS   Ramakrishnan,V., Reeves,P.S., DeGuzman,F., Deshpande,U.,
            Ministri-Madrid,K., DuBridge,R.B. and Phillips,D.R.
  TITLE     Increased thrombin responsiveness in platelets from mice lacking
            glycoprotein V
  JOURNAL   Proc Natl Acad Sci U S A 96 (23), 13336-13341 (1999)
   PUBMED   10557321
REFERENCE   5  (bases 1 to 2215)
  AUTHORS   Ravanat,C., Morales,M., Azorsa,D.O., Moog,S., Schuhler,S.,
            Grunert,P., Loew,D., Van Dorsselaer,A., Cazenave,J.P. and Lanza,F.
  TITLE     Gene cloning of rat and mouse platelet glycoprotein V:
            identification of megakaryocyte-specific promoters and
            demonstration of functional thrombin cleavage
  JOURNAL   Blood 89 (9), 3253-3262 (1997)
   PUBMED   9129030
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Nov 27, 2020 this sequence version replaced NM_012795.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.15110.1,
                                           SRR26643285.47428.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                JAXUCZ010000011.1  83948507-83948535
            30-2215             JAXUCZ010000011.1  83949414-83951599
FEATURES             Location/Qualifiers
     source          1..2215
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..2215
                     /gene="Gp5"
                     /gene_synonym="PLGPV"
                     /note="glycoprotein V (platelet)"
                     /db_xref="GeneID:25259"
                     /db_xref="RGD:2724"
     exon            1..29
                     /gene="Gp5"
                     /gene_synonym="PLGPV"
                     /inference="alignment:Splign:2.1.0"
     exon            30..2215
                     /gene="Gp5"
                     /gene_synonym="PLGPV"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1735
                     /gene="Gp5"
                     /gene_synonym="PLGPV"
                     /note="platelet glycoprotein V; Platelete glycoprotein 5;
                     GPV; Platelet glycoprotein 5; glycoprotein 5, platelet"
                     /codon_start=1
                     /product="platelet glycoprotein V precursor"
                     /protein_id="NP_036927.2"
                     /db_xref="GeneID:25259"
                     /db_xref="RGD:2724"
                     /translation="MLRSVLLSAVLSLVGAQPFPCPKTCKCVVRDAVQCSGGSVAHIA
                     ELGLPTNLTHILLFRMDRGVLQSHSFSGMTVLQRLMLSDSHISAIDPGTFNDLVKLKT
                     LRLTRNKISHLPRAILDKMVLLEQLFLDHNALRDLDQNLFQKLLNLRDLCLNQNQLSF
                     LPANLFSSLGKLKVLDLSRNNLTHLPQGLLGAQIKLEKLLLYSNRLMSLDSGLLANLG
                     ALTELRLERNHLRSIAPGAFDSLGNLSTLTLSGNLLESLPPALFLHVSCVTRLTLFEN
                     PLEELPEVLFGEMAGLRELWLNGTHLRTLPAAAFRNLSGLQTLGLTRNPLLSALPRGM
                     FHGLTELRVLALHTNALEELPEDALRGLGRLRQVSLRHNRLRALPRTLFRNLSSLVTV
                     QLEHNQLKTLPGDVFAALPQLTRVLLGHNPWLCDCGLWPFLQWLRHHLELLGRDEPPQ
                     CNGPESRASLTFWELLQGDQWCPDPRGLPPDPPTENALKAPDPTQRPNSSQSWAWVQL
                     VARGESPDNRFYWNLYILLLIAQATIAGFIVFAMIKIGQLFRTLIREELLFEAMGKSS
                     N"
ORIGIN      
        1 agtcagtcca gggtgcagag ctgcttcaga catgctaagg agcgtcctac tgtccgcggt
       61 gctctcacta gtaggcgccc aacccttccc ctgccccaaa acctgcaagt gtgtggtccg
      121 cgatgccgtg caatgctccg gcggcagcgt ggctcacatc gctgagctag gtctgcccac
      181 gaacctcaca cacatcctgc tcttcagaat ggaccgggga gtattgcaga gccacagctt
      241 cagcggcatg acggtccttc agcgcctgat gctctcagat agccacattt ctgccatcga
      301 ccccggcacc ttcaatgacc tggtaaaact aaaaaccctc aggttgacgc gcaacaaaat
      361 ctctcatctt ccacgtgcga tcctggataa gatggtgctt ttggaacagc tgttcttgga
      421 ccacaatgca ctaagggacc ttgaccaaaa cctgtttcag aaactgctta acctgcggga
      481 tctctgtttg aaccagaatc agctctcctt tcttcctgct aaccttttct cgagcctggg
      541 aaagctgaag gtgttggatt tatcgcgaaa caacctgacc cacctgcccc agggattact
      601 tggggcgcaa attaagcttg agaaactgct gctctattca aaccggctca tgtctctgga
      661 ttcggggctg ctggccaacc tgggcgccct gactgagctg cggctggagc ggaatcacct
      721 tcgctccatc gcaccgggtg ccttcgacag cctcggaaac ctgagcacct tgactctgtc
      781 cggaaacctc ctggagtctc tgccgcccgc gctcttcctt catgtgagct gcgtgactcg
      841 gctgaccctg ttcgagaacc ctctggagga gctcccggag gtgctgttcg gggagatggc
      901 cggcctgcgg gagctgtggc tgaacggcac ccacctgcgc acgctgcccg ccgccgcctt
      961 ccgcaacctg agcggcctgc agacgctggg gctgacacgg aacccgctcc tgagcgcgct
     1021 cccgcgcggc atgttccacg gcctgacgga gctgcgcgtg ctcgcgctgc acaccaatgc
     1081 cctggaggag ctgccggagg acgcgctgcg cggcctcggg cgcctgcgcc aggtgtcgct
     1141 gcgccacaac cggttgcggg ccctgccccg cacgctcttc cgtaacctca gcagcctcgt
     1201 gacggtgcag cttgagcata accagctgaa gaccctgcca ggagacgtgt tcgcggctct
     1261 gccccaactg acccgggtcc tgctcggtca caacccctgg ctctgcgact gtggcctgtg
     1321 gcccttcctc cagtggctgc ggcatcacct ggagctccta ggccgagatg agcctccgca
     1381 gtgcaatggc ccagagtcac gcgccagcct gacgttctgg gagctgctgc agggtgacca
     1441 gtggtgccca gatcctcgcg gtctgcctcc cgaccctcca accgaaaatg ctctgaaagc
     1501 cccggatccg acccagcggc ccaatagctc gcagtcctgg gcgtgggtcc agctggtggc
     1561 caggggtgaa agtcccgata accgcttcta ctggaatctt tatattctac ttctaatagc
     1621 ccaggccacc atagccgggt tcatcgtgtt tgccatgatt aaaatcggcc agctgtttcg
     1681 aacattaatc agagaggagc tcttgtttga ggcaatggga aaatcgtcta actaatcaaa
     1741 ctgtgaccag agcattgtgg acggggcccc aagaagaatc cagtcaggat gctgtgtgcc
     1801 attcctccat ttcccctctc ccagttcttc ctctcagtgt cccttctccc ctctccccag
     1861 aaggaccttt tgtaaaatcg ctactgcttt ctagcctggc ctggttttcc tcctctgttg
     1921 ttaggttcgg gagctggggg tgggggtggg gtgcacagga cttagcttgt gtttggctca
     1981 tcccgtccca ttgtgcagcg ttgggtgcct ggtggagaga ggagctcttt cttggtttct
     2041 gagtctgagg ccacatcctg ccaggtgggc aagacctctc ctgcaccgag caaggattga
     2101 gtaacatttg tggaaggaac accggcctaa agcgaaccct agatcccaga gatgaaggct
     2161 cttcccagga acaagctgga gtgttcttgt ccctttctac ctgaaaggag aattc
//
