LOCUS       NM_001007720            2177 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus golgi reassembly stacking protein 2 (Gorasp2),
            mRNA.
ACCESSION   NM_001007720 NM_138829 XM_346653 XM_579651
VERSION     NM_001007720.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2177)
  AUTHORS   Piao,H., Kim,J., Noh,S.H., Kweon,H.S., Kim,J.Y. and Lee,M.G.
  TITLE     Sec16A is critical for both conventional and unconventional
            secretion of CFTR
  JOURNAL   Sci Rep 7, 39887 (2017)
   PUBMED   28067262
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2177)
  AUTHORS   Kim,J., Noh,S.H., Piao,H., Kim,D.H., Kim,K., Cha,J.S., Chung,W.Y.,
            Cho,H.S., Kim,J.Y. and Lee,M.G.
  TITLE     Monomerization and ER Relocalization of GRASP Is a Requisite for
            Unconventional Secretion of CFTR
  JOURNAL   Traffic 17 (7), 733-753 (2016)
   PUBMED   27062250
REFERENCE   3  (bases 1 to 2177)
  AUTHORS   Feng,Y., Yu,W., Li,X., Lin,S., Zhou,Y., Hu,J. and Liu,X.
  TITLE     Structural insight into Golgi membrane stacking by GRASP65 and
            GRASP55 proteins
  JOURNAL   J Biol Chem 288 (39), 28418-28427 (2013)
   PUBMED   23940043
  REMARK    GeneRIF: GRASP65 and GRASP55 proteins have roles in Golgi membrane
            stacking
REFERENCE   4  (bases 1 to 2177)
  AUTHORS   Truschel,S.T., Zhang,M., Bachert,C., Macbeth,M.R. and Linstedt,A.D.
  TITLE     Allosteric regulation of GRASP protein-dependent Golgi membrane
            tethering by mitotic phosphorylation
  JOURNAL   J Biol Chem 287 (24), 19870-19875 (2012)
   PUBMED   22523075
REFERENCE   5  (bases 1 to 2177)
  AUTHORS   Gee,H.Y., Noh,S.H., Tang,B.L., Kim,K.H. and Lee,M.G.
  TITLE     Rescue of DeltaF508-CFTR trafficking via a GRASP-dependent
            unconventional secretion pathway
  JOURNAL   Cell 146 (5), 746-760 (2011)
   PUBMED   21884936
REFERENCE   6  (bases 1 to 2177)
  AUTHORS   Duran,J.M., Kinseth,M., Bossard,C., Rose,D.W., Polishchuk,R.,
            Wu,C.C., Yates,J., Zimmerman,T. and Malhotra,V.
  TITLE     The role of GRASP55 in Golgi fragmentation and entry of cells into
            mitosis
  JOURNAL   Mol Biol Cell 19 (6), 2579-2587 (2008)
   PUBMED   18385516
  REMARK    GeneRIF: GRASP55 has no role in the organization of Golgi membranes
            per se, but it controls their fragmentation by regulating the
            release of a partner, which requires a G2-specific phosphorylation
            at T225/T249.
REFERENCE   7  (bases 1 to 2177)
  AUTHORS   Wu,C.C., MacCoss,M.J., Mardones,G., Finnigan,C., Mogelsvang,S.,
            Yates,J.R. 3rd and Howell,K.E.
  TITLE     Organellar proteomics reveals Golgi arginine dimethylation
  JOURNAL   Mol Biol Cell 15 (6), 2907-2919 (2004)
   PUBMED   15047867
REFERENCE   8  (bases 1 to 2177)
  AUTHORS   Barr,F.A., Preisinger,C., Kopajtich,R. and Korner,R.
  TITLE     Golgi matrix proteins interact with p24 cargo receptors and aid
            their efficient retention in the Golgi apparatus
  JOURNAL   J Cell Biol 155 (6), 885-891 (2001)
   PUBMED   11739402
REFERENCE   9  (bases 1 to 2177)
  AUTHORS   Short,B., Preisinger,C., Korner,R., Kopajtich,R., Byron,O. and
            Barr,F.A.
  TITLE     A GRASP55-rab2 effector complex linking Golgi structure to membrane
            traffic
  JOURNAL   J Cell Biol 155 (6), 877-883 (2001)
   PUBMED   11739401
REFERENCE   10 (bases 1 to 2177)
  AUTHORS   Shorter,J., Watson,R., Giannakou,M.E., Clarke,M., Warren,G. and
            Barr,F.A.
  TITLE     GRASP55, a second mammalian GRASP protein involved in the stacking
            of Golgi cisternae in a cell-free system
  JOURNAL   EMBO J 18 (18), 4949-4960 (1999)
   PUBMED   10487747
  REMARK    GeneRIF: Identification of GRASP55, and demonstration that it
            functions in the stacking of Golgi cisternae in a similar manner to
            the related protein GRASP65.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078731.1.
            
            On or before Oct 20, 2005 this sequence version replaced
            NM_138829.1, XM_346653.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078731.1, AF110267.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2177
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q22"
     gene            1..2177
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /note="golgi reassembly stacking protein 2"
                     /db_xref="GeneID:113961"
                     /db_xref="RGD:619911"
     exon            1..91
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1393
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /note="golgi reassembly-stacking protein of 55 kDa; Golgi
                     reassembly-stacking protein 2-like"
                     /codon_start=1
                     /product="Golgi reassembly-stacking protein 2"
                     /protein_id="NP_001007721.1"
                     /db_xref="GeneID:113961"
                     /db_xref="RGD:619911"
                     /translation="MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSIN
                     GSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRF
                     CSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKP
                     LKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEEGKKISLPGQ
                     MTGTPMTPPKDGFTEVQLSSVSPPSLSPPGTAGVEQSLSGLSISSAPPAVSNVLSTGV
                     PTVPLLPPQVNQSLASVPPMNPAATLPSLMPLSAGLPSLPNLPSLSNFNLPAPHIMPG
                     VGLPELGKPGLPPLPSLPPRNLPGIAPLPMPSDFLPSFPLVPEGSSAASAGEPLSSLP
                     AMGPPSDPVMTTAKADTSSLTVDVMSPASKVPTTVEDRVSDCTPAMEKPVSAVTDANA
                     SEAS"
     exon            92..172
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            173..376
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            377..463
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            464..594
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            595..727
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            728..851
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            852..938
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1058
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..2148
                     /gene="Gorasp2"
                     /gene_synonym="GRASP55; Grs2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctgggtcg tacggatcgc ccgccgccat gggctcctcg cagagcgtcg agatcccggg
       61 cggcggcaca gagggctacc acgtcctgcg ggtacaggaa aattccccag gacacagagc
      121 tggactggag cctttctttg actttattgt ttctattaat ggttcgagat taaataagga
      181 caacgacact ctgaaggact tgctgaaagc caacgtagag aagcctgtga agatgctcat
      241 ctacagcagc aaaaccctgg agctgcggga ggcctcggtc acacccagca acctgtgggg
      301 cggccagggc ttgttggggg ttagcatccg gttctgcagt ttcgatgggg ccaacgaaaa
      361 tgtttggcac gtgctggaag tggaatcgaa ttcccccgca gcactggcgg ggctgagacc
      421 tcacagcgat tacatcattg gagctgatac cgtcatgaat gagtctgaag acctgttcag
      481 ccttattgag acccatgaag caaagcctct taagctctac gtgtacaaca cagacactga
      541 caactgccga gaagtgatca ttacaccaaa ttctgcatgg ggtggggaag gcagcctcgg
      601 ctgtggcatc ggctatggtt atttgcaccg aatacctacg cgtccctttg aagaaggaaa
      661 gaagatttcc cttccaggac aaatgactgg cacccccatg actcctccta aggatgggtt
      721 tacggaggtc cagctgtcct cagtcagccc cccatctttg tcaccaccag gaactgcagg
      781 agttgagcag agtctgtctg gactgtccat tagctcagct ccaccggctg tcagcaatgt
      841 tctcagtaca ggtgtaccga ctgtaccatt gttgccgcca caagtaaacc agtcccttgc
      901 ttctgtgcca ccaatgaacc cagctgccac attaccaagt ctgatgcctt tgtcagcagg
      961 gctgcctagc ctccccaacc tccccagcct ctccaacttc aacctccctg ctccgcacat
     1021 catgccaggg gtcggcttgc cagagctcgg gaagccgggt ttgccacctc ttccgtcctt
     1081 gcctccccga aacttacctg gcattgcacc tctccccatg ccgtccgact tcctcccgtc
     1141 attccctttg gttccagagg gctcttctgc agccagcgca ggggaaccac tgtcttccct
     1201 tcctgccatg ggcccacctt ctgaccctgt catgactact gcaaaggcag acacctcctc
     1261 cctcactgtg gatgtgatgt ctcctgcttc caaggtcccc accactgttg aggacagagt
     1321 gagcgactgc accccagcca tggagaagcc tgtgtctgca gttacggatg caaatgcttc
     1381 tgaggcttct taacttggaa tcaaccttca gaactgatgt ggtctgtcta tttaaccatg
     1441 ggatcatatc tggaatcgca aactaccatt gatttcatct agtttgtacg tatctgtagg
     1501 ggtcctgtac ataattctaa ggggaaactg cacaagagtc tgagggcttg tctcccacca
     1561 agttggggga attacagcca aggaggggaa tctgagaatg tgcttgtatt ttaaacaacc
     1621 aaaaaaagtt gttatgggtg gcttgctgcc aggcatctgc tgccattctg ggatgtacgt
     1681 ctttggaaga gacggcgggg gcctgctaga atccctgtac cactgctacg ccttgtgtaa
     1741 ggagatgaga tattttatgc ctagtgccca cacgcaacat ttcttgtact ttgtaagtcg
     1801 tttgcaagaa cacagaccac ctcactaaac tgtaaaagga aacaagaatt taatgttggt
     1861 ctctgtgagt cgcatctcta ttaaggttta cacagaactc ccagtcgaag atgttttgtt
     1921 ccggttacat gcacactgtt aattgaacat ctttttattc tgcctgtaca cagatcttgt
     1981 tttgaactca gaattactca gacaccgttt tgtagctgct gctgttgctt tagatgcccg
     2041 tggtaagatg gcattaaaga gaaatagagg agggctgcac tctgtagcta cttcatggta
     2101 tggcgaccct gggagagcga agacggcaat aaacttcagt cgctttgtaa aaaaaaaaaa
     2161 aaaaaaaaaa aaaaaaa
//
