LOCUS       NM_023977               2530 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus golgi phosphoprotein 3 (Golph3), mRNA.
ACCESSION   NM_023977
VERSION     NM_023977.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2530)
  AUTHORS   You,H., Li,T., Zhang,J., Lei,Q., Tao,X., Xie,P. and Lu,W.
  TITLE     Reduction in ischemic cerebral infarction is mediated through golgi
            phosphoprotein 3 and Akt/mTOR signaling following salvianolate
            administration
  JOURNAL   Curr Neurovasc Res 11 (2), 107-113 (2014)
   PUBMED   24606552
  REMARK    GeneRIF: GOLPH3 may be involved in the mitochondrial oxidative
            stress during cerebral ischemia/reperfusion injury
REFERENCE   2  (bases 1 to 2530)
  AUTHORS   Farber-Katz,S.E., Dippold,H.C., Buschman,M.D., Peterman,M.C.,
            Xing,M., Noakes,C.J., Tat,J., Ng,M.M., Rahajeng,J., Cowan,D.M.,
            Fuchs,G.J., Zhou,H. and Field,S.J.
  TITLE     DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3
  JOURNAL   Cell 156 (3), 413-427 (2014)
   PUBMED   24485452
REFERENCE   3  (bases 1 to 2530)
  AUTHORS   Zhou,X., Zhan,W., Bian,W., Hua,L., Shi,Q., Xie,S., Yang,D., Li,Y.,
            Zhang,X., Liu,G. and Yu,R.
  TITLE     GOLPH3 regulates the migration and invasion of glioma cells though
            RhoA
  JOURNAL   Biochem Biophys Res Commun 433 (3), 338-344 (2013)
   PUBMED   23500462
REFERENCE   4  (bases 1 to 2530)
  AUTHORS   Ng,M.M., Dippold,H.C., Buschman,M.D., Noakes,C.J. and Field,S.J.
  TITLE     GOLPH3L antagonizes GOLPH3 to determine Golgi morphology
  JOURNAL   Mol Biol Cell 24 (6), 796-808 (2013)
   PUBMED   23345592
REFERENCE   5  (bases 1 to 2530)
  AUTHORS   Ali,M.F., Chachadi,V.B., Petrosyan,A. and Cheng,P.W.
  TITLE     Golgi phosphoprotein 3 determines cell binding properties under
            dynamic flow by controlling Golgi localization of core 2
            N-acetylglucosaminyltransferase 1
  JOURNAL   J Biol Chem 287 (47), 39564-39577 (2012)
   PUBMED   23027862
REFERENCE   6  (bases 1 to 2530)
  AUTHORS   Schmitz,K.R., Liu,J., Li,S., Setty,T.G., Wood,C.S., Burd,C.G. and
            Ferguson,K.M.
  TITLE     Golgi localization of glycosyltransferases requires a Vps74p
            oligomer
  JOURNAL   Dev Cell 14 (4), 523-534 (2008)
   PUBMED   18410729
REFERENCE   7  (bases 1 to 2530)
  AUTHORS   Snyder,C.M., Mardones,G.A., Ladinsky,M.S. and Howell,K.E.
  TITLE     GMx33 associates with the trans-Golgi matrix in a dynamic manner
            and sorts within tubules exiting the Golgi
  JOURNAL   Mol Biol Cell 17 (1), 511-524 (2006)
   PUBMED   16236792
  REMARK    GeneRIF: GMx33 is a member of the trans-Golgi matrix and offer
            clues regarding the role of the trans-Golgi matrix in sorting and
            exit from the Golgi
REFERENCE   8  (bases 1 to 2530)
  AUTHORS   Nakashima-Kamimura,N., Asoh,S., Ishibashi,Y., Mukai,Y., Shidara,Y.,
            Oda,H., Munakata,K., Goto,Y. and Ohta,S.
  TITLE     MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial
            mass in response to mitochondrial dysfunction
  JOURNAL   J Cell Sci 118 (Pt 22), 5357-5367 (2005)
   PUBMED   16263763
REFERENCE   9  (bases 1 to 2530)
  AUTHORS   Bell,A.W., Ward,M.A., Blackstock,W.P., Freeman,H.N.,
            Choudhary,J.S., Lewis,A.P., Chotai,D., Fazel,A., Gushue,J.N.,
            Paiement,J., Palcy,S., Chevet,E., Lafreniere-Roula,M., Solari,R.,
            Thomas,D.Y., Rowley,A. and Bergeron,J.J.
  TITLE     Proteomics characterization of abundant Golgi membrane proteins
  JOURNAL   J Biol Chem 276 (7), 5152-5165 (2001)
   PUBMED   11042173
REFERENCE   10 (bases 1 to 2530)
  AUTHORS   Wu,C.C., Taylor,R.S., Lane,D.R., Ladinsky,M.S., Weisz,J.A. and
            Howell,K.E.
  TITLE     GMx33: a novel family of trans-Golgi proteins identified by
            proteomics
  JOURNAL   Traffic 1 (12), 963-975 (2000)
   PUBMED   11208086
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC092568.1.
            
            On Apr 11, 2005 this sequence version replaced NM_023977.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092568.1, AF311954.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2530
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q16"
     gene            1..2530
                     /gene="Golph3"
                     /gene_synonym="Gmx33"
                     /note="golgi phosphoprotein 3"
                     /db_xref="GeneID:78961"
                     /db_xref="RGD:621226"
     exon            1..334
                     /gene="Golph3"
                     /gene_synonym="Gmx33"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..1006
                     /gene="Golph3"
                     /gene_synonym="Gmx33"
                     /note="coat protein GPP34; trans-Golgi protein GMx33;
                     golgi phosphoprotein 3 (coat-protein)"
                     /codon_start=1
                     /product="Golgi phosphoprotein 3"
                     /protein_id="NP_076467.2"
                     /db_xref="GeneID:78961"
                     /db_xref="RGD:621226"
                     /translation="MTSLTQRSSGLVQRRTEASRNAADKERAAGGGGGSGEDEAQSRR
                     DEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGR
                     LQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGET
                     WNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQ
                     EAVLDKWVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDP
                     EVECLKANTNEVLWAVVAAFTK"
     exon            335..466
                     /gene="Golph3"
                     /gene_synonym="Gmx33"
                     /inference="alignment:Splign:2.1.0"
     exon            467..581
                     /gene="Golph3"
                     /gene_synonym="Gmx33"
                     /inference="alignment:Splign:2.1.0"
     exon            582..2506
                     /gene="Golph3"
                     /gene_synonym="Gmx33"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgccccagc tccgagaatt aacacggaag ctcctggggc cgggaccgtg agggagagcc
       61 ggccggtccc gcgtccctgt cggtctggcg cggctcttcg gctggagcca tgacctcgct
      121 gacccagcgg agctcgggcc tggtgcagcg gcgcaccgag gcctcgcgga acgctgccga
      181 caaggagcgg gcggcgggcg gcggcggcgg cagcggcgag gatgaggcgc aaagccgccg
      241 cgacgagcag gacgacgacg acaagggcga ctccaaggaa acgcggctga ccctgatgga
      301 ggaggtgctc ctgctgggcc tcaaggaccg agagggttac acatcatttt ggaatgactg
      361 tatatcatct ggattacgtg gctgtatgtt aattgaatta gctttgagag gaaggttaca
      421 gttagaggct tgtggaatga gaagaaaaag tcttttaaca agaaaggtga tctgtaaatc
      481 ggatgctcca acaggagatg ttcttcttga tgaagctcta aagcatgtta aggagactca
      541 gcctccagag acagtccaga actggatcga gttacttagt ggtgagacgt ggaatccatt
      601 aaaattgcat tatcagttaa gaaatgtacg ggaacgatta gctaaaaacc tggtagaaaa
      661 gggtgtactg acgacagaga aacagaactt cctcctgttt gacatgacga cacatcctct
      721 caccaacaac aacattaagc agcgcctcat caagaaggta caggaagctg ttcttgacaa
      781 atgggtaaat gaccctcacc gaatggacaa gcgcttgctg gccctcattt acctagccca
      841 tgcctcagat gttttggaaa atgcttttgc tcctcttctg gacgagcagt atgatttagc
      901 caccaagaga gtacggcagc ttctcgactt agacccagaa gtggagtgtc tgaaggccaa
      961 caccaacgaa gttctctggg ccgtggtagc tgcgtttacc aagtaactgt cagaatgcaa
     1021 tgtttccttt ctctcatgtg aaccagtagc ttttcttcta ttgactctgg ttttctgcag
     1081 tttgtacttt cccacactaa taattggctt ttgttctaca aaacggtggg tggctatttc
     1141 tttttgtatg tacgcaggat tctgctggta cgagaggcct tcctctttct gtttgtaatc
     1201 aaccttattg ccatattggc acttcattcc ctgctcattc tcactgtttc ctgttctggg
     1261 tctctggtgt actttgactt tcagagtacc tctagtcacc cgcctcatgc acagcgcttg
     1321 gattacctca gcttgcgttt tcccacatgt gcttactcac atggccttct gcctacagtt
     1381 cacacaagtc acaaccaggc cttcaactca ccaaaggtaa atatctgtat ctattaggac
     1441 attttataca tagacctcag ttgagatgta tacttagcaa aattattttt aaattgaaac
     1501 agcacagtaa atacataata taaaatgccc cttgaacttt tgcttcctat gtaaatctgt
     1561 tatatgatta cagttgttat aattttagct attaaatcat aaaggtccaa ttgtttcaca
     1621 aagccagttt ggaatgggct gcattccact tatgctgtat atagtttgaa ttatatatga
     1681 atcgcccctt cttctggcca cctctgcctc gttttagtat ttgaaaaatt taattttgca
     1741 tctggtgccc ctcacttgct tcattctttg ttatttgatg gcaaaataga cctctcatca
     1801 ttgaaggaga gaggagatgt gtgactcctt cagggctctt tgtgagctat gttcctcatg
     1861 atagtctgcc tgtgcatctc ttttgggact ttttttttct ttaacttttc ctgttttatg
     1921 atttctatag gaaagaggct tgtgaccagt actaatcttg agtacagttt ttttttttgt
     1981 tgttgttgtt ttgtttttcc acttttctgt ccttaagtaa attaatgtct gctctgaaat
     2041 accgtttacc tactcatctt ttcttggaga aaagaaaatc aaatatcagt cctagcagat
     2101 gttgcatgta atttggtagc aagtaacgac tacgacttga tgattaagaa tttcgtaaca
     2161 gaaagctctg ctgtgtttta atttttatat gcaattatga taattagcac accttaagac
     2221 tatcaacctt tgtgttttaa tgttgatttt attcattatc actgtttatt tactatcagt
     2281 ttcataatgt aaatattata cattgaacaa attaaatgtc aaatttttat tactatagtt
     2341 catgttaata gtggggcttt caggtgtcta gaaacttttg gtgaacattt gatgcaaaaa
     2401 gactagatgc gtataacttt agagttgaat tttaagggag tcctaatatg tatactatct
     2461 ttttatctgg agtaataaat aaactatgat cttgaaagtg cctgaaaaaa aaaaaaaaaa
     2521 aaaaaaaaaa
//
