LOCUS       NM_001100493            1217 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus N-acetylglucosamine-1-phosphate transferase
            subunit gamma (Gnptg), mRNA.
ACCESSION   NM_001100493 XM_001059345 XM_213240
VERSION     NM_001100493.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1217)
  AUTHORS   Encarnacao M, Kollmann K, Trusch M, Braulke T and Pohl S.
  TITLE     Post-translational modifications of the gamma-subunit affect
            intracellular trafficking and complex assembly of
            GlcNAc-1-phosphotransferase
  JOURNAL   J Biol Chem 286 (7), 5311-5318 (2011)
   PUBMED   21173149
REFERENCE   2  (bases 1 to 1217)
  AUTHORS   Qian Y, Lee I, Lee WS, Qian M, Kudo M, Canfield WM, Lobel P and
            Kornfeld S.
  TITLE     Functions of the alpha, beta, and gamma subunits of
            UDP-GlcNAc:lysosomal enzyme
            N-acetylglucosamine-1-phosphotransferase
  JOURNAL   J Biol Chem 285 (5), 3360-3370 (2010)
   PUBMED   19955174
REFERENCE   3  (bases 1 to 1217)
  AUTHORS   Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE and
            Yates JR.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   4  (bases 1 to 1217)
  AUTHORS   Raas-Rothschild A, Cormier-Daire V, Bao M, Genin E, Salomon R,
            Brewer K, Zeigler M, Mandel H, Toth S, Roe B, Munnich A and
            Canfield WM.
  TITLE     Molecular basis of variant pseudo-hurler polydystrophy
            (mucolipidosis IIIC)
  JOURNAL   J Clin Invest 105 (5), 673-681 (2000)
   PUBMED   10712439
REFERENCE   5  (bases 1 to 1217)
  AUTHORS   Lukong KE, Elsliger MA, Mort JS, Potier M and Pshezhetsky AV.
  TITLE     Identification of
            UDP-N-acetylglucosamine-phosphotransferase-binding sites on the
            lysosomal proteases, cathepsins A, B, and D
  JOURNAL   Biochemistry 38 (1), 73-80 (1999)
   PUBMED   9890884
REFERENCE   6  (bases 1 to 1217)
  AUTHORS   Madiyalakan,R., Chowdhary,M.S., Rana,S.S. and Matta,K.L.
  TITLE     Lysosomal-enzyme targeting: the phosphorylation of synthetic
            D-mannosyl saccharides by UDP-N-acetyl-glucosamine:lysosomal-enzyme
            N-acetylglucosamine-phosphotransferase from rat-liver microsomes
            and fibroblasts
  JOURNAL   Carbohydr Res 152, 183-194 (1986)
   PUBMED   3021329
REFERENCE   7  (bases 1 to 1217)
  AUTHORS   Lang,L., Reitman,M., Tang,J., Roberts,R.M. and Kornfeld,S.
  TITLE     Lysosomal enzyme phosphorylation. Recognition of a
            protein-dependent determinant allows specific phosphorylation of
            oligosaccharides present on lysosomal enzymes
  JOURNAL   J Biol Chem 259 (23), 14663-14671 (1984)
   PUBMED   6094568
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158818.1.
            
            On or before Jun 4, 2008 this sequence version replaced
            XM_213240.4, XM_001059345.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158818.1, BC098716.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN14984038
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1217
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1217
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /note="N-acetylglucosamine-1-phosphate transferase subunit
                     gamma"
                     /db_xref="GeneID:287134"
                     /db_xref="RGD:1311614"
     exon            1..68
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..937
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /note="N-acetylglucosamine-1-phosphotransferase, gamma
                     subunit; N-acetylglucosamine-1-phosphate transferase,
                     gamma subunit; N-acetylglucosamine-1-phosphotransferase
                     subunit gamma"
                     /codon_start=1
                     /product="N-acetylglucosamine-1-phosphotransferase subunit
                     gamma precursor"
                     /protein_id="NP_001093963.1"
                     /db_xref="GeneID:287134"
                     /db_xref="RGD:1311614"
                     /translation="MAGRLTGFLMLLGLAAQGPAPTHAGKMKVVEEPNTFGLNNPFLP
                     QASRLQPKREPSAVSGPPHLFRLAGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYS
                     GILGIWHEWEIVNNTFKGMWMTDGDSCHSRSRQSKVELTCGKTNRLAHVSEPSTCVYA
                     LTFETPLVCHPHSLLVYPTLSEALQQRWDQVEQDLADELITPQGYEKLLRALFEDAGY
                     LKVPGETHPTQLAGDSKGLGLETLDICRKAHAELSREVQRLTSLLEQHGIPHTQPTET
                     THSQLLGQQLPVGEISEQLRGDPGLRGNIL"
     exon            69..126
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            127..194
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            195..249
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            250..333
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            334..427
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            428..542
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            543..625
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            626..757
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            758..839
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
     exon            840..1176
                     /gene="Gnptg"
                     /gene_synonym="Gnptag"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcgaccctg ggagcgatgg cggggcggct gactggcttc ctgatgttgc tggggctcgc
       61 ggcgcagggg cctgcgccga cacatgccgg gaagatgaag gtggtggagg agcccaacac
      121 tttcgggctg aataacccgt tcttgcccca ggcaagccga cttcagccca agagagagcc
      181 ttcggctgta tctgggcccc cgcatctctt cagactcgct ggcaagtgct tcagcctagt
      241 ggagtccacg tacaagtatg aattctgccc tttccacaac gtgacccagc atgagcagac
      301 cttccgttgg aacgcctaca gcgggatcct tggcatctgg catgagtggg agatcgtcaa
      361 caacaccttc aagggcatgt ggatgactga tggggactcc tgtcactccc ggagccggca
      421 gagcaaggtg gagctcacct gtggaaagac caaccgactg gcccacgtgt ctgaaccaag
      481 cacctgcgtc tatgcattga catttgagac ccctcttgtc tgccatcccc actctctgtt
      541 agtgtatcca accctgtcag aggccctgca gcagcgctgg gaccaggtgg aacaggacct
      601 ggcggacgag ctgatcacac cgcagggcta tgagaagttg ctgagggcac tttttgagga
      661 tgctggctac ttaaaggtcc caggagaaac ccaccccacc cagctggcag gagattccaa
      721 gggcctgggg cttgagactc tggacatttg cagaaaggca cacgcagagc tgtcacggga
      781 ggtacaaaga ctgacaagtc tgctcgaaca gcatggaatc ccacacactc agcccacaga
      841 aaccacccac tctcagctcc tgggtcagca gctcccggta ggtgaaatct cagagcagtt
      901 gcggggcgac ccaggactac gagggaacat cctgtgagcc aggcggccat gaagaacaga
      961 aatgttctga gccttgagtg tcttttcaga gagaggccaa gtgtggtctc agcagagtgc
     1021 accaaactgg tgtggtgtgg acatggcttc ttttggcatc ttctaggcca gacaatatca
     1081 ctgacaagag ggacctgctg gccagccttt gttgtgccca aagatccaga caaaataaag
     1141 attcgaagtt ttaattaatt ccatactcat aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1201 aaaaaaaaaa aaaaaaa
//
