LOCUS       NM_001134756            1664 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus glucosamine-phosphate N-acetyltransferase 1
            (Gnpnat1), transcript variant 2, mRNA.
ACCESSION   NM_001134756 XM_001072812 XM_573746
VERSION     NM_001134756.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S
            and Russo T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   2  (bases 1 to 1664)
  AUTHORS   Wang J, Liu X, Liang YH, Li LF and Su XD.
  TITLE     Acceptor substrate binding revealed by crystal structure of human
            glucosamine-6-phosphate N-acetyltransferase 1
  JOURNAL   FEBS Lett 582 (20), 2973-2978 (2008)
   PUBMED   18675810
REFERENCE   3  (bases 1 to 1664)
  AUTHORS   Bouche C, Serdy S, Kahn CR and Goldfine AB.
  TITLE     The cellular fate of glucose and its relevance in type 2 diabetes
  JOURNAL   Endocr Rev 25 (5), 807-830 (2004)
   PUBMED   15466941
  REMARK    Review article
REFERENCE   4  (bases 1 to 1664)
  AUTHORS   Boehmelt G, Fialka I, Brothers G, McGinley MD, Patterson SD, Mo R,
            Hui CC, Chung S, Huber LA, Mak TW and Iscove NN.
  TITLE     Cloning and characterization of the murine glucosamine-6-phosphate
            acetyltransferase EMeg32. Differential expression and intracellular
            membrane association
  JOURNAL   J Biol Chem 275 (17), 12821-12832 (2000)
   PUBMED   10777580
REFERENCE   5  (bases 1 to 1664)
  AUTHORS   Oikawa,S., Sato,H. and Akamatsu,N.
  TITLE     Glucosamine 6-phosphate acetylase in rat ascites hepatomas
  JOURNAL   Int J Biochem 18 (10), 929-933 (1986)
   PUBMED   3792612
REFERENCE   6  (bases 1 to 1664)
  AUTHORS   Oikawa,S. and Akamatsu,N.
  TITLE     Three forms of rat liver glucosamine 6-phosphate acetylase and the
            changes in their levels during development
  JOURNAL   Int J Biochem 17 (1), 73-80 (1985)
   PUBMED   3996734
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA339205.1, BC160861.1 and AI502591.1.
            
            On or before Sep 5, 2008 this sequence version replaced
            XM_001072812.1, XM_573746.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EX489830.1, FQ222000.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                CA339205.1         71-151
            82-1638             BC160861.1         88-1644
            1639-1664           AI502591.1         1-26                c
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1664
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /note="glucosamine-phosphate N-acetyltransferase 1"
                     /db_xref="GeneID:498486"
                     /db_xref="RGD:1563144"
     exon            1..73
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /inference="alignment:Splign:2.1.0"
     exon            74..241
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..642
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /EC_number="2.3.1.4"
                     /codon_start=1
                     /product="glucosamine 6-phosphate N-acetyltransferase"
                     /protein_id="NP_001128228.1"
                     /db_xref="GeneID:498486"
                     /db_xref="RGD:1563144"
                     /translation="MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGEGLVLRPL
                     CTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATAT
                     LIIEHKFIHSCAKRGRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQ
                     NVGFYKKFDYTVSEENYMCRRFLK"
     exon            242..304
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /inference="alignment:Splign:2.1.0"
     exon            305..432
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /inference="alignment:Splign:2.1.0"
     exon            433..494
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /inference="alignment:Splign:2.1.0"
     exon            495..1648
                     /gene="Gnpnat1"
                     /gene_synonym="RGD1563144"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggatccgg atgcggcggc gctgtgaccc gcaggcagac tgacgcgctg ggacgggagc
       61 gtggctcgct ccgattttac tagaaagatg aaacctgatg aaactcctat gtttgacccg
      121 agtttgctca aagaagtgga ctggagtcag aatacagcta tattttctcc agccatttct
      181 ccaatgcatc ctggagaagg cttggttttg aggcctctct gtactgcgga cttaaataaa
      241 ggttttttta aggtattggg tcagttgaca gagactggtg tcgtcagccc ggagcagttc
      301 atgaaatctt ttgagcatat gaagaagtct ggggattact atgttacagt tgtggaagat
      361 gtgaccctag gacaaattgt ggctacagca actctgatca tagaacataa atttatccat
      421 tcatgtgcta agagagggag agtagaagat gtggtcgtta gtgacgagtg cagagggaaa
      481 cagcttggca aactgttatt atcaactctg actttgctaa gcaagaaact aaactgttac
      541 aagatcaccc ttgaatgtct accacaaaat gttggtttct acaaaaagtt tgactacacg
      601 gtatcagaag aaaattacat gtgtcggagg ttcctaaagt aaaaaccacc attgagaggt
      661 tacttgatgc tactgtttta gagttcattt ttgttgctgc aaccagtgag ctccctaact
      721 actagactga aaaatgctgt agtgtgccag tgtagtgcca cgagaggatg cctgtggctg
      781 ctgggagtgc aaatgatcag aaaggggggt gattttttaa ccaaaggaat atattttcaa
      841 cttgaatctt ttcttgcatt gtatttttct acagtttgtc ttcctttctt ggtagtcaag
      901 agtatgggta gtaaacagtt atgtcatctg ctctctgctg ctcactttta aatacatgta
      961 tatatatatg tgtatgtata tatgtatata tacatgtata tatatatacg tgtgtatata
     1021 tatattgatt gattgaataa gggtgtttct taccataaaa ttatttttgt ctccgacatc
     1081 taatagactt aggcacacca tttctcacat tacagggagt tgggcacttt ggttaccatg
     1141 accaccagat acatatttga acattgtcga tcctaactct gcacacaaaa caatctttgg
     1201 acagtctttt taaagcaaca aaggaaaaga aaaatgggac aaggtacaac agcttaaata
     1261 actattttgt gtatagttct gtgcagctac tgtcccatct ttctcatctg tcaaataagg
     1321 gtcaagttct ccaagttctc caagggcaga cacagagatc cagggtcctt tccatcagtg
     1381 agtgagttgc taccttggtt tctatatcgt gacatctgaa gcctttgaat cataaaaatg
     1441 tgtggtactg cctttggtac agctttaaaa tggtagcttt tctatttaat gtgattataa
     1501 tggtactatg attctgatca ctgtcctatt ttatttattt gaatgatttt tagaaacaga
     1561 atcagatact tttattaata atggttctaa tcttttgcat tccatgttac tatattaaac
     1621 ttgtttatat gaatagtctc tcatattaaa aaaaaaaaaa aaaa
//
