LOCUS       NM_024138               2897 bp    mRNA    linear   ROD 26-APR-2024
DEFINITION  Rattus norvegicus G protein subunit gamma 7 (Gng7), mRNA.
ACCESSION   NM_024138
VERSION     NM_024138.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2897)
  AUTHORS   Lai,W.S. and Ding,Y.L.
  TITLE     GNG7 silencing promotes the proliferation and differentiation of
            placental cytotrophoblasts in preeclampsia rats through activation
            of the mTOR signaling pathway
  JOURNAL   Int J Mol Med 43 (5), 1939-1950 (2019)
   PUBMED   30864685
  REMARK    GeneRIF: GNG7 silencing repressed apoptosis and enhanced the
            proliferation and differentiation of placental cytotrophoblasts in
            preeclampsia rats through activation of the mTOR signaling pathway.
REFERENCE   2  (bases 1 to 2897)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 2897)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2897)
  AUTHORS   Pahner,I., Holtje,M., Winter,S., Takamori,S., Bellocchio,E.E.,
            Spicher,K., Laake,P., Nurnberg,B., Ottersen,O.P. and
            Ahnert-Hilger,G.
  TITLE     Functional G-protein heterotrimers are associated with vesicles of
            putative glutamatergic terminals: implications for regulation of
            transmitter uptake
  JOURNAL   Mol Cell Neurosci 23 (3), 398-413 (2003)
   PUBMED   12837624
  REMARK    Erratum:[Mol Cell Neurosci. 2003 Nov;24(3):850. Numberg, Bernd
            [corrected to Nurnberg, Bernd]]
REFERENCE   5  (bases 1 to 2897)
  AUTHORS   Schwindinger,W.F., Betz,K.S., Giger,K.E., Sabol,A., Bronson,S.K.
            and Robishaw,J.D.
  TITLE     Loss of G protein gamma 7 alters behavior and reduces striatal
            alpha(olf) level and cAMP production
  JOURNAL   J Biol Chem 278 (8), 6575-6579 (2003)
   PUBMED   12488442
REFERENCE   6  (bases 1 to 2897)
  AUTHORS   Watson,J.B., Coulter,P.M. 2nd, Margulies,J.E., de Lecea,L.,
            Danielson,P.E., Erlander,M.G. and Sutcliffe,J.G.
  TITLE     G-protein gamma 7 subunit is selectively expressed in medium-sized
            neurons and dendrites of the rat neostriatum
  JOURNAL   J Neurosci Res 39 (1), 108-116 (1994)
   PUBMED   7807587
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from L23219.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L23219.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2897
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2897
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /note="G protein subunit gamma 7"
                     /db_xref="GeneID:58979"
                     /db_xref="RGD:61860"
     exon            1..208
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     exon            209..324
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..450
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /note="guanine nucleotide binding protein (G protein),
                     gamma 7 subunit; guanine nucleotide binding protein, gamma
                     7; heterotrimeric guanine nucleotide-binding protein 3b"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-7"
                     /protein_id="NP_077052.1"
                     /db_xref="GeneID:58979"
                     /db_xref="RGD:61860"
                     /translation="MMSGTNNVAQARKLVEQLRIEAGIERIKVSKASSELMSYCEQHA
                     RNDPLLVGVPASENPFKDKKPCIIL"
     exon            325..2897
                     /gene="Gng7"
                     /gene_synonym="Hg3b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggcaccaaa ccctagtttg ccggggcctc cggagcagct ggctgagggt tcctgtcgct
       61 gcctgggccg ggtgtgacct cccgtccaca cagacccaga caccagcctg gcaccctgcg
      121 gtgccaaatt aatgcacagt atttctcttc cagggtgtga agccttccta ttggaacctc
      181 ggtgctggga cagtgggact cagagcagct ctctagacgc caggtccacg ctcatggctg
      241 atgatgtcag gtactaacaa cgtcgcccag gcccggaagc tggtggagca gttgcgcatc
      301 gaagctggga tcgaacgcat caaggtctcc aaggcctcgt cagaactgat gagctactgt
      361 gagcaacatg cccggaatga ccccttgctg gttggtgtac cagcctctga aaatccattc
      421 aaagacaaaa agccttgcat aattctctag ttctctctct cttcctccct ccttcctctc
      481 cctctctttc tccccacccc aaaggtattg tccagttttt cctgtaagaa aaaaatattt
      541 gaatcccttc tactttgaat tttaaaggaa cagaaaccat tgtgaatgcc tggagcctcc
      601 tgacctagct ggagttcgtc ctggcctaac tttagcctca tccaccccct cccgtcgaga
      661 accactgatg tgacagtttt taagctcccc ttagttggcc tggggaaagg gttctgttgg
      721 ccaacggcga gcctagcaag tttgcggacc atagctgcag tcctcgggtc ccacataaaa
      781 catgcaggtg cggtgtcaga aggctgagat ggaaggatcc ccgaggcttg gggactgcat
      841 cctagcagcc agtaaactcc agacagtgag aaacgatgcc tccaaacaca aggcagagga
      901 ggatacccag ccttgacctc tggctccaca cgcggcacac acaatgcacc ctgtactacc
      961 cagtgtcatt ctcgagtggc cctgtcgtgt gcacggtgac agtgatgccc tttctccaga
     1021 gagttggccc attctagaaa cgggcatttg ggtctccata caaaggaagc acttgctggt
     1081 atggccgagt gtgtaacttt gtctccgaag cctgagatcc atgtgttcat tggtgactcc
     1141 tcgtttttct cccagttaca cagatggttg tgagggcaga agtgcagatt taattatctt
     1201 gaggtgattg agaaggaccg atggggttct ccatcccaca cgtgactgtg cctccagatc
     1261 ccccttcctg ggtcaaacta ttttttaact aactagaacc caagtccctc aatgtgtgga
     1321 ctgtggccat tttctgcact ccttcattgg gagattcatc tctgaccaca cccccaaccc
     1381 ctcactgagg gattctagac ggggctccac ccctgaccac gccccagtcc cccattgagg
     1441 gattctagaa ggggttccac ctctgaccat gcctcagccc cctactgggg attctagaag
     1501 gggctccacc ctgaccacgc ccccagaccc ttactggtaa attctagatg gcactccact
     1561 tctgaggcgg gcatcttctc tattgtgtga gcagagccct agagtccagg ctggcctgga
     1621 ctggaactgg agatcttcct gcctctggct ccggagtacc tacctgatag gcctgtgttg
     1681 catgcctggc atcggattgg acggaagatg acagaccgtc tgtctatgac agtgacagtg
     1741 gcaggtctag ggaggacaca gcttaggtgt gccagtgtgg tctgcagcca tacacaaagg
     1801 catctcaagc atttgagact ccagttacct ctttctcctg ccggatcagt gtgggagcag
     1861 aaatgaagcc agtccagtta ctccctgcag ctctggtgga aatctgcttc ccaaaccctg
     1921 tgccaggctc atccctggac agttgctcaa actgcccatg ggcaaagtga atggagctgg
     1981 cagatctggc tcctagccta ttaggcacaa cctaccacct agataaggtg gcagcccccc
     2041 ccctccccag tccatttgat ggaatcaggg aaagaagttt gggatgtgac taagggggag
     2101 gggcactgca ggtgctaaga gaggaccctg tttccccctc catgggccac agagagcaca
     2161 gaccaagggt caggcccctc ctgtgcactg actcccaatt actggtcaga gagggccagg
     2221 actttggtga gcctgactct cagaacctgt ggtggaatca gaaaagccag tgtccctcca
     2281 gaactgcagc cacctttcat taggctagga accaggtccc agcaggtgtg tctccagctg
     2341 cactggcagg ggacagtgag gagagaggaa aggacataca ttctggggac cgggactgca
     2401 gaacacccag ccagtatggt agaaacctgg gttccacccc aagctcgcaa aaaaacaggc
     2461 atgggcactg gggatgtaga ggcaggaaga tcagaacttc agggtctttc tcagccacag
     2521 gatgggctca aggttagcct gggctgcatg agaccatgtc tcaaagacag aaatctcagt
     2581 gtgctctctc atgttcctaa cacgcctgat tgtttccctc tggaggctgc tgtgccagcc
     2641 tggccagcct gcgtttggtc gcagccttgt ttctcagctc tgggacaaaa actcaaatct
     2701 gcatctctgc ccacacctcc agttccccct ccccgggtga ctcacaggcc aaggacaaag
     2761 tggcctcttg ctcccaggga gggtaggatg tgctggtgta gcctgtgtac gtcctaagca
     2821 ctggagccct gcctcggcct agagacgctt agggaaacca gaacacatca gagcaattag
     2881 gagccaagaa tggtggc
//
