LOCUS       NM_024377               1393 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus G protein subunit gamma 5 (Gng5), mRNA.
ACCESSION   NM_024377
VERSION     NM_024377.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Moon,A.M., Stauffer,A.M., Schwindinger,W.F., Sheridan,K.,
            Firment,A. and Robishaw,J.D.
  TITLE     Disruption of G-protein gamma5 subtype causes embryonic lethality
            in mice
  JOURNAL   PLoS One 9 (3), e90970 (2014)
   PUBMED   24599258
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  AUTHORS   Ahmed,S.M., Theriault,B.L., Uppalapati,M., Chiu,C.W., Gallie,B.L.,
            Sidhu,S.S. and Angers,S.
  TITLE     KIF14 negatively regulates Rap1a-Radil signaling during breast
            cancer progression
  JOURNAL   J Cell Biol 199 (6), 951-967 (2012)
   PUBMED   23209302
REFERENCE   3  (bases 1 to 1393)
  AUTHORS   Aoyama,C., Sugimoto,H., Ando,H., Yamashita,S., Horibata,Y.,
            Sugimoto,S. and Satou,M.
  TITLE     The heterotrimeric G protein subunits Galpha(q) and Gbeta(1) have
            lysophospholipase D activity
  JOURNAL   Biochem J 440 (2), 241-250 (2011)
   PUBMED   21812758
REFERENCE   4  (bases 1 to 1393)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 1393)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 1393)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 1393)
  AUTHORS   Fisher,K.J. and Aronson,N.N. Jr.
  TITLE     Characterization of the cDNA and genomic sequence of a G protein
            gamma subunit (gamma 5)
  JOURNAL   Mol Cell Biol 12 (4), 1585-1591 (1992)
   PUBMED   1549114
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 26, 2020 this sequence version replaced NM_024377.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M95780.1, SRR22399489.3641824.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               JAXUCZ010000002.1  238054954-238055059
            107-246             JAXUCZ010000002.1  238058581-238058720
            247-1393            JAXUCZ010000002.1  238062305-238063451
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q44"
     gene            1..1393
                     /gene="Gng5"
                     /note="G protein subunit gamma 5"
                     /db_xref="GeneID:79218"
                     /db_xref="RGD:620807"
     exon            1..106
                     /gene="Gng5"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..232
                     /gene="Gng5"
                     /note="guanine nucleotide binding protein gamma 5; G
                     protein gamma-5 subunit; guanine nucleotide binding
                     protein (G protein), gamma 5 subunit"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-5"
                     /protein_id="NP_077353.1"
                     /db_xref="GeneID:79218"
                     /db_xref="RGD:620807"
                     /translation="MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQ
                     HDPLLTGVSSSTNPFRPQKVCSFL"
     exon            107..246
                     /gene="Gng5"
                     /inference="alignment:Splign:2.1.0"
     exon            247..1393
                     /gene="Gng5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttggcccg gctgtcccga gcgccatgtc gggttcttct agcgtcgccg ccatgaagaa
       61 ggtggttcag caactccggc tggaggccgg gctcaaccgc gtgaaggttt cccaggcagc
      121 tgcagacttg aaacagttct gtctgcagaa tgctcaacat gaccctctgc tgactggagt
      181 gtcttcaagt acaaatccct tcagacccca gaaagtctgc tcctttttgt agtcatatat
      241 ctcgaggttt ctcaaactac ttttcatgaa ccagtgaata ttcacgagaa ctaagttcga
      301 agtcactaag tttgaagtct gtacagaagc ttctctttaa cacgtgccat acacataatc
      361 ttctactcgt cagtccttaa catctacctc tctggatttt catggatctc tgtttcacaa
      421 ggtttaactg ttttatatac actggctgta gcatacaata aagcagcata caaacttttg
      481 gccttgttat tgatatgaaa tgtgctgtat actaattttt tcaacatcag gactcactgc
      541 cttattggca aggcttctag gaatttacag aacaactgca aatctttgtt caaaggccgg
      601 aagacttaag agtttctaat ccttcagtca gttatgggaa ttatcttaaa tatcccaaat
      661 ataggtaggg agatggctcg gtggctaaga gcacttgctc tgcagttagt tatgctgagt
      721 tcagatcctg ccacccatgt aaaaagctgg gcgtggctgt acatgcccgt ggccacagcc
      781 cttcggggag atggtttgtt ggctgccagc gagggtaagg ttgtaattag ctccgtgaga
      841 acgaggcaga aagggataca ggtgcctgac actgccatgt gggctcacac aggcaacaaa
      901 caactctagt ggcgtcagca gttagtgcta ccaagaaggt ggctgcttcc atctggaaaa
      961 agagttaaag attcacagaa tcaagacctt gaggacttac gacaatgcct caagtaggca
     1021 agtggaggta attaggtaga aaggaacaag aaaacaggtt aacctctgtg acctgtaact
     1081 ttgctccaag tcccaataac ctgtccttta gaactggtat attaaatcag ggtcatacac
     1141 tatctaccaa caagcctttt ttctagccta caagttcttt gggaatgaaa attataaagt
     1201 ttgaatcgtc attcctaaga aattattaca actaatccaa aatgacaaca gcttttatga
     1261 ctttcataca taatttttca gacaaaaata aaattatatt tatttatatt tactatatgc
     1321 agtggaaact catagcactt ggtcatttct tcaaacacag gatttataaa ataaaatccc
     1381 attttgaaaa gta
//
