LOCUS       NM_053542               1810 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus G protein subunit alpha 15 (Gna15), mRNA.
ACCESSION   NM_053542
VERSION     NM_053542.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1810)
  AUTHORS   Rhee,S.G.
  TITLE     Regulation of phosphoinositide-specific phospholipase C
  JOURNAL   Annu Rev Biochem 70, 281-312 (2001)
   PUBMED   11395409
  REMARK    Review article
REFERENCE   2  (bases 1 to 1810)
  AUTHORS   Davignon,I., Catalina,M.D., Smith,D., Montgomery,J., Swantek,J.,
            Croy,J., Siegelman,M. and Wilkie,T.M.
  TITLE     Normal hematopoiesis and inflammatory responses despite discrete
            signaling defects in Galpha15 knockout mice
  JOURNAL   Mol Cell Biol 20 (3), 797-804 (2000)
   PUBMED   10629036
REFERENCE   3  (bases 1 to 1810)
  AUTHORS   Feild,J.A., Foley,J.J., Testa,T.T., Nuthulaganti,P., Ellis,C.,
            Sarau,H.M. and Ames,R.S.
  TITLE     Cloning and characterization of a rabbit ortholog of human Galpha16
            and mouse G(alpha)15
  JOURNAL   FEBS Lett 460 (1), 53-56 (1999)
   PUBMED   10571060
REFERENCE   4  (bases 1 to 1810)
  AUTHORS   Kusakabe,Y., Yamaguchi,E., Tanemura,K., Kameyama,K., Chiba,N.,
            Arai,S., Emori,Y. and Abe,K.
  TITLE     Identification of two alpha-subunit species of GTP-binding
            proteins, Galpha15 and Galphaq, expressed in rat taste buds
  JOURNAL   Biochim Biophys Acta 1403 (3), 265-272 (1998)
   PUBMED   9685675
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 24, 2020 this sequence version replaced NM_053542.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.9552.1,
                                           SRR26643292.28148.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-414               JAXUCZ010000007.1  8835624-8836037
            415-599             JAXUCZ010000007.1  8844096-8844280
            600-754             JAXUCZ010000007.1  8846082-8846236
            755-883             JAXUCZ010000007.1  8846529-8846657
            884-1013            JAXUCZ010000007.1  8849597-8849726
            1014-1167           JAXUCZ010000007.1  8850533-8850686
            1168-1810           JAXUCZ010000007.1  8855627-8856269
FEATURES             Location/Qualifiers
     source          1..1810
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1810
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /note="G protein subunit alpha 15"
                     /db_xref="GeneID:89788"
                     /db_xref="RGD:619751"
     exon            1..414
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..1394
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /note="g alpha-15; guanine nucleotide binding protein,
                     alpha 15; heterotrimeric guanine nucleotide-binding
                     protein 1l"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein subunit
                     alpha-15"
                     /protein_id="NP_445994.2"
                     /db_xref="GeneID:89788"
                     /db_xref="RGD:619751"
                     /translation="MARSLTWGCCPWCLTEEEKTAARIDQEINKILLEQKKQERGELK
                     LLLLGPGESGKSTFIKQMRIIHGAGYSEEDRRAFRLLVYQNIFVSMQAMIEAMDRLQI
                     PFSRPDSKQHASLVMTQDPYKVSSFEKPYAVAMQYLWRDAGIRACYERRREFHLLDSA
                     VYYLSHLERIAEDDYIPTAQDVLRSRMPTTGINEYCFSVQKTKLRIVDVGGQKSERKK
                     WIHCFENVIALIYLASLSEYDQCLEENSQENRMKESLALFSTILELPWFKSTSVILFL
                     NKTDILEDKIHTSHLASYFPSFQGPRRDAEAAKRFILDMYARVYASCAEPHDGGRKGS
                     RARRLFAHFTCATDTHSVRSVFKDVRDSVLARYLDEINLL"
     exon            415..599
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            600..754
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            755..883
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1013
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1167
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1810
                     /gene="Gna15"
                     /gene_synonym="Hg1l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggagcttc caccaccgac ctgtctggcg ggcacggcca ggtctgggca agttggaggg
       61 ggcgggaagc agcacctagg tccccgccct gtttccagca cccaggcctc ttgaagcctt
      121 tgcctgggct cccacaggcc ctgggcaggg acacgggggt cctggaggga cctccacccc
      181 ccactccatc cagagaagaa agaatccggt agctggggct gtgcaggctg caggagcaat
      241 gtcgcctggt ggcctgtgag gcgcccacca tggcccggtc cctgacttgg ggctgctgtc
      301 cctggtgcct gacggaagag gagaagactg ccgccagaat cgaccaggag atcaacaaga
      361 ttttgttgga acagaagaaa caagagcgcg gggaattgaa actcctgctg ttggggcccg
      421 gtgagagcgg gaaaagcacg ttcatcaagc aaatgcgcat cattcacggc gccggctact
      481 ctgaggagga ccgcagagcc ttccggctgc tcgtctacca gaacatcttc gtctccatgc
      541 aggccatgat tgaagcaatg gacaggctgc agatcccctt cagcaggccg gacagcaagc
      601 agcacgccag cctggtgatg acccaggacc cctataaagt gagctcgttc gagaagccat
      661 atgcagtggc catgcagtac ctgtggcggg acgcgggcat ccgcgcatgc tacgagcgga
      721 ggcgtgaatt ccacctgctg gactccgcgg tgtactacct gtcacacctg gagcgcatcg
      781 ccgaggacga ctacatcccc actgcgcagg acgtgctgcg cagtcgcatg cccaccactg
      841 gcatcaatga gtactgcttt tccgtgcaga aaaccaaact gcgcatcgtg gatgttggcg
      901 gccagaagtc agaacgtaag aaatggatcc actgtttcga gaacgtgatt gccctcatct
      961 acctggcgtc tctgagcgag tatgaccagt gtctggagga gaacagtcag gagaaccgta
     1021 tgaaggagag tctcgctctg tttagcacga tcctagagct gccctggttc aagagcacct
     1081 cggtcatcct cttcctcaac aagacagaca tcctggagga taaaatccac acctcccacc
     1141 tagcctcata cttccccagc ttccagggac cccggaggga cgcagaggcc gccaagcgct
     1201 tcatcttgga catgtacgcg cgcgtgtacg cgagctgtgc agagccccac gacggtggca
     1261 ggaagggatc ccgcgcgcgc cgcctcttcg cacacttcac ctgtgccacg gacacgcaca
     1321 gcgtccgcag cgtgttcaag gacgtgcggg actcagtgct ggcccggtac ctggacgaga
     1381 tcaacctgtt gtgacacggg gaacccgaag cggtggtggc gaggacactg cgccccctgg
     1441 tggccactct cggaactgca ggccaaggaa gtcagtccag agtctgctcc ccacggggcc
     1501 tccaagccca gcccctctgt aatttatccc ctcactctcc tagctgttag agaaaggacc
     1561 tttaacccca gcgctcggag gcagaggcag gaggatctct gtgagttccg ggatcctggg
     1621 ccaaaaacaa acaaacaaaa ccggatagaa ctgtccgggg cttgtgactt cccagggatc
     1681 ctgtccaagt cctcctgtgg gcctcatgct gggtaagtga aatgtgcaag gaaggaagtt
     1741 ctacttgctg tctacccatt ggttggactg aggtagactc caattaaaga ttgacttttg
     1801 atatatcgta
//
