LOCUS       NM_001025056            1662 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus GDP-mannose pyrophosphorylase A (Gmppa), mRNA.
ACCESSION   NM_001025056 XM_576592
VERSION     NM_001025056.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Verachtert,H., Rodriguez,P., Bass,S.T. and Hansen,R.G.
  TITLE     Purification and properties of guanosine diphosphate hexose
            pyrophosphorylase from mammalian tissues
  JOURNAL   J Biol Chem 241 (9), 2007-2013 (1966)
   PUBMED   5946626
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083763.1.
            
            [WARNING] On Aug 1, 2024 this sequence was replaced by
            NM_001025056.2.
            
            On Jun 25, 2005 this sequence version replaced XM_576592.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083763.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132274, SAMD00132291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..1662
                     /gene="Gmppa"
                     /note="GDP-mannose pyrophosphorylase A"
                     /db_xref="GeneID:501167"
                     /db_xref="RGD:1560644"
     exon            1..191
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            192..252
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     CDS             213..1475
                     /gene="Gmppa"
                     /EC_number="2.7.7.13"
                     /note="GTP-mannose-1-phosphate guanylyltransferase alpha"
                     /codon_start=1
                     /product="mannose-1-phosphate guanyltransferase alpha"
                     /protein_id="NP_001020227.1"
                     /db_xref="GeneID:501167"
                     /db_xref="RGD:1560644"
                     /translation="MLKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEAC
                     AQVPGMQEILLIGFYQPDEALTQFLEAAQQEFNLPVRYLQEFTPLGTGGGLYHFRDQI
                     LAGAPEAFFVLNADVCSDFPLSAMLDAHRLQRHPFLLLGTTANRTQSLNYGCIVENPQ
                     THEVLHYVEKPSTFISDIINCGIYLFSPEALKPLRDVFQRNQQDGQLEESPGSWPGAG
                     TIRLEQDVFSALAGQGQIYVHLTDGIWSQIKSAGSALYASRLYLGRYQITHPERLARH
                     TAGGPRIRGNVYIHPTAKVAPSAVLGPNVSIGKGVTIGEGVRLRESIVLHGATLQEHT
                     CVLHSIVGWGSTVGRWARVEGTPNDPNPNDPRARMDSESLFKDGKLLPAITILGCRVR
                     IPAEVLILNSIVLPHKELSRSFTNQIIL"
     exon            253..350
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            351..454
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            455..641
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            642..701
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            702..832
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            833..967
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1065
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1112
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1205
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1374
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1638
                     /gene="Gmppa"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggtggtgg gcagggtagg ggtaagggac gaaccctcga cgtagggagg gttcgcaagg
       61 cctgccttgc tctcctcatg cccacgcttg tgttggtggc tacgagaagc tgacatctat
      121 tggacagact caattgtggg gtccagaagg tcagcaatca atctttagaa tccagagatt
      181 ccacaccggt ggtttaggtc acaacgacca tcatgctcaa agctgtgatc ctcattggag
      241 gaccccagaa ggggactcgc ttcaggcctt tgtcttttga agtgcccaaa ccgttgttcc
      301 ctgtggcagg tgtccctatg atccagcacc atatagaagc ctgtgcccag gtccctggga
      361 tgcaggagat tctactcatt ggcttctacc agcctgatga ggctctcacc cagttcctgg
      421 aagctgcaca gcaggagttt aaccttccag tcaggtatct gcaggagttc actccccttg
      481 gcacaggggg tggcctctac cattttcggg accagatcct ggctggcgca cctgaggcct
      541 tcttcgtgct caatgctgat gtctgttctg acttccctct gagtgccatg ttggatgctc
      601 acaggctcca acgccaccct ttcctactcc ttggcaccac ggcgaacagg acacaatctc
      661 tcaactacgg ctgcatcgtt gagaatccac agacgcatga ggtcctgcac tatgtggaga
      721 aacccagcac ctttatcagc gacatcatca actgtggcat ctaccttttc tccccagaag
      781 ccctgaagcc tctccgggat gttttccagc gtaatcagca ggatgggcaa ctggaggaat
      841 ctccaggctc ctggcctggt gcagggacca tccgactaga gcaggatgtg ttctcagccc
      901 tggctgggca gggccaaatc tatgtgcacc tcaccgacgg catctggagc cagatcaagt
      961 cggcaggctc ggccctttat gcttcccgcc tgtatctggg gcgataccag atcacccacc
     1021 cagaacggct agccagacac actgcagggg gcccacgaat cagaggaaat gtttacatcc
     1081 atccaactgc taaagtggcc ccatcagctg tgctgggccc caatgtctcc attgggaagg
     1141 gggtgaccat aggcgagggt gtgcgtctgc gggagagtat tgtcctccat ggagccacac
     1201 tgcaggaaca cacctgtgtc cttcacagca ttgtgggctg ggggagcact gtggggcgct
     1261 gggcccgcgt agaggggact cccaatgacc ccaatcccaa tgacccccgc gcccgcatgg
     1321 acagcgagag cctcttcaaa gatggaaagc tacttcctgc catcaccatc ctgggctgcc
     1381 gagtacggat ccccgctgag gtgcttatct tgaactcgat tgttctacca cataaggagc
     1441 tgagtcgaag cttcaccaac caaatcattc tgtgaggtgc tgcccaagga ctccacccac
     1501 tctcctgtgg gatgccgcct gcctgaccag ctctgtccag aaaggacctg aggaagccac
     1561 ctcataggga gccatgtgtg tggctgggga cacctggcct ccctccccac ccccaaataa
     1621 acccctgtga accttggaaa aaaaaaaaaa aaaaaaaaaa aa
//
