LOCUS       NM_001009648            1660 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus glycine-N-acyltransferase (Glyat), transcript
            variant 1, mRNA.
ACCESSION   NM_001009648 XM_006231121 XM_215137
VERSION     NM_001009648.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Wen,H., Yang,H.J., An,Y.J., Kim,J.M., Lee,D.H., Jin,X., Park,S.W.,
            Min,K.J. and Park,S.
  TITLE     Enhanced phase II detoxification contributes to beneficial effects
            of dietary restriction as revealed by multi-platform metabolomics
            studies
  JOURNAL   Mol Cell Proteomics 12 (3), 575-586 (2013)
   PUBMED   23230277
  REMARK    GeneRIF: Data indicate that the up-regulation of phase II
            detoxification in the DR group was confirmed by mRNA and protein
            expression levels of uridinediphospho-glucuronosyltransferase and
            glycine-N-acyltransferase in actual liver tissues.
REFERENCE   2  (bases 1 to 1660)
  AUTHORS   Matsuo,M., Terai,K., Kameda,N., Matsumoto,A., Kurokawa,Y.,
            Funase,Y., Nishikawa,K., Sugaya,N., Hiruta,N. and Kishimoto,T.
  TITLE     Designation of enzyme activity of glycine-N-acyltransferase family
            genes and depression of glycine-N-acyltransferase in human
            hepatocellular carcinoma
  JOURNAL   Biochem Biophys Res Commun 420 (4), 901-906 (2012)
   PUBMED   22475485
REFERENCE   3  (bases 1 to 1660)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Oct 5, 2022 this sequence version replaced
            XM_006231121.4, NM_001009648.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.3303.1,
                                           SRR26643286.4295.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                JAXUCZ010000001.1  219128926-219129017
            93-177              JAXUCZ010000001.1  219131225-219131309
            178-272             JAXUCZ010000001.1  219135208-219135302
            273-380             JAXUCZ010000001.1  219142321-219142428
            381-507             JAXUCZ010000001.1  219144513-219144639
            508-679             JAXUCZ010000001.1  219147621-219147792
            680-1660            JAXUCZ010000001.1  219148635-219149615
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1660
                     /gene="Glyat"
                     /note="glycine-N-acyltransferase"
                     /db_xref="GeneID:293779"
                     /db_xref="RGD:1307163"
     exon            1..92
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
     exon            93..177
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
     exon            178..272
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..1082
                     /gene="Glyat"
                     /EC_number="2.3.1.13"
                     /EC_number="2.3.1.71"
                     /note="AAc; acyl-CoA:glycine N-acyltransferase; aralkyl
                     acyl-CoA N-acyltransferase; glycine N-benzoyltransferase;
                     liver regeneration-related protein LRRG067; aralkyl
                     acyl-CoA:amino acid N-acyltransferase; benzoyl-coenzyme
                     A:glycine N-acyltransferase"
                     /codon_start=1
                     /product="glycine N-acyltransferase"
                     /protein_id="NP_001009648.1"
                     /db_xref="GeneID:293779"
                     /db_xref="RGD:1307163"
                     /translation="MIVPLQGAQMLQMLEKSLKKYLPESLKVYGTIYHVNHGNPFNLK
                     ALVDKWPDFNTVVVRPQEQEMKDDLDFYTNTYQIYSKDPENCQEFLGSSEVINWKQHL
                     QIQSSQSHLNKAIQNLASIHSLQVKHSENILYVVSETVRKLFPSLLDTKNLSPGSGKP
                     KAINQEMFKLSSLDVTHAALVNKFWLFGGNERSQRFIERCIKNFPSSCVLGPEGTPAS
                     WTLMDQTGEMRMGGTVPQYRAQGLVSFVIYSQDQIMKKRGFPVYSHTDKSNTVMQKMS
                     YSLQHLPMPCAWNQWICVPM"
     exon            273..380
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
     exon            381..507
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
     exon            508..679
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
     exon            680..1660
                     /gene="Glyat"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcttcagg ttctcactga acctactgta tcggaaggga cttcacctcc cagaagtcca
       61 tttttatgaa gactgttgag acagctttcc agaaactaga accatgtgga agatagacct
      121 tggagtattc ctgtgcggat tatcttgatt acgttaatta attctggatg ggactaggct
      181 aaagtgtcat catgattgtt ccattacaag gtgcacagat gctacaaatg ctggagaaat
      241 ccttgaagaa gtaccttcct gaatccttaa aggtctatgg gaccatctat catgtgaacc
      301 atggaaaccc attcaatcta aaagccctag tagacaagtg gcctgatttt aacacagtgg
      361 ttgtccgccc tcaagaacag gaaatgaaag atgaccttga tttctacact aacacttacc
      421 aaatctactc caaagacccc gagaactgtc aggagttcct gggctcctca gaagtcatta
      481 actggaaaca gcatttgcag attcaaagtt cccagtccca cctgaataaa gcaatacaaa
      541 atcttgcaag catccattct ctccaagtca aacactcaga aaacatcctc tatgtggtat
      601 cagagacagt taggaaactg ttcccttccc tgctggatac aaagaattta tcaccaggaa
      661 gtggcaagcc caaggctatc aatcaagaga tgtttaaact ttcatctttg gatgttaccc
      721 atgctgcatt ggtgaataaa ttctggcttt ttggtggcaa cgagaggagt cagagattca
      781 tcgaacgctg cataaagaac ttcccaagtt cctgtgtctt ggggcctgag ggaacccctg
      841 catcttggac tctaatggac caaactggag agatgcgaat gggaggcacc gtgcctcagt
      901 accgggccca aggtcttgtc tcctttgtta tctattcaca agaccagatt atgaagaaac
      961 gtggctttcc tgtttattct cacactgaca aaagcaatac tgttatgcaa aaaatgagtt
     1021 actcactgca gcatctcccc atgccctgtg cctggaacca gtggatatgt gtacctatgt
     1081 gaagctggac tcaaacacaa gatgatgtcg ggtgggccgg gggatgtaat tggatggtga
     1141 gcaaagagtg aaggtgattg aaaagagaga ataaatggca gccagctgca aaagagagct
     1201 gctgtctgtg ctctggggaa gcagtgtgaa tggccaacag atctccataa ctcctttttg
     1261 tcagattgct cctagacttc ccttaagttc ctgagtttga agcaggccta tacccttcgg
     1321 tactggactc atgtaattta gccccttcat atttctagga tttatgtaac attcctttat
     1381 catctgctcc aaatggctcc tcctagaaac catagtacaa aatttggaaa cttctgctac
     1441 ccttactagc aatagggaga gtatgttttc tgactactgt gcctattccc ctctgtctat
     1501 tgcctttcct tcagtgatca gcaagtgaat tctccttata atgtcttaag gaagtagctg
     1561 cccctctgtt gggtgcttca tagatatgtt aaatacatca ttatacatgg atcatatact
     1621 ttatcagatt aaacacaata tatataaaac atcaaaagaa
//
