LOCUS       XM_343404               4958 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus glucuronic acid epimerase (Glce),
            transcript variant X1, mRNA.
ACCESSION   XM_343404
VERSION     XM_343404.8
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 1, 2024 this sequence was replaced by
            NM_001427627.1.
            
            On Jan 21, 2021 this sequence version replaced XM_343404.7.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4958
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4958
                     /gene="Glce"
                     /note="glucuronic acid epimerase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 43
                     ESTs, 2 long SRA reads, 10 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 195 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:363073"
                     /db_xref="RGD:1565253"
     CDS             336..2192
                     /gene="Glce"
                     /codon_start=1
                     /product="D-glucuronyl C5-epimerase"
                     /protein_id="XP_343405.2"
                     /db_xref="GeneID:363073"
                     /db_xref="RGD:1565253"
                     /translation="MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRHLS
                     SGFRVDGLEKRSAASESNHYANHIAKQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGL
                     KYEEIDCLINDEHTIRGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSK
                     VYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYG
                     LSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMASVADKSRSTNVKQFIA
                     PEAGEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTDKNQLFTVHYVSNTQLIAFK
                     DRDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFL
                     DNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQ
                     AISTLVRAYLLTKDYVFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSF
                     VLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHF
                     MLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN"
ORIGIN      
        1 gcatggcctc gcccctcacc gtggctggga tctcgcggga agagccgcgg gcacggcagc
       61 ggctccgctc cccggtagcg cgccgagcgg gcgggctctc ctcacacgag cgcttcctcg
      121 ccgagaggct ggagctgcgg caacgcaggc ctgggccgcc gtgtctccgc cgcccgcttc
      181 agttttcctc agggctctgg gggtcgctcg tccgccaatg cgcctcagga atttaacaag
      241 aaactgaagt ttcaaagatt caaatatttt ttgaattgaa gccagaaatg tactaagatt
      301 ttgattcttt catttgatta aggtatggtc tgaatatgcg ttgtttggca gctcgggtca
      361 actataagac tttgattatc atctgtgcgt tattcacttt ggtcacagta cttttgtgga
      421 ataagtgttc cagcgacaaa gcaatccagt ttcctcggca cttgagtagt ggattcagag
      481 tggatggatt agaaaaaaga tcagcagcat ctgaaagtaa ccactatgcc aaccacatag
      541 ccaagcagca gtcagaggag gcatttcctc aggaacaaca gaaggcaccc cctgttgttg
      601 ggggcttcaa tagcaatggg ggaagcaagg tgttagggct caaatatgaa gagattgact
      661 gtctcataaa tgatgaacac acaattagag ggagacgaga ggggaatgaa gtttttcttc
      721 cattcacttg ggtagagaaa tactttgatg tttatggaaa agttgtccag tatgatggct
      781 atgatcgatt tgaattctct catagctatt ccaaagtcta tgcacagaga tcaccttacc
      841 accctgacgg tgtgtttatg tcctttgaag gatacaatgt ggaagtccga gacagagtca
      901 agtgtataag tggagttgaa ggtgtgccat tatctacaca atgggggcct caaggctatt
      961 tctacccaat ccagattgcg cagtatgggc tcagtcatta cagcaagaat ctaaccgaga
     1021 aaccccctca catagaggta tacgagacag cagaagacag ggacagaaac atcagaccta
     1081 atgaatggac tgtgcccaag ggctgcttca tggccagtgt ggctgataag tctagatcca
     1141 ccaatgttaa acagtttatt gctccagaag ccggtgaggg tgtgtctttg cagctgggaa
     1201 atacaaagga cttcattatc tcattcgacc tcaagttctt aacaaacgga agtgtgtctg
     1261 tggttctgga gaccacagac aagaatcagc tcttcactgt gcactatgtc tcaaataccc
     1321 agctaattgc ttttaaagac agggacatat actacggcat tgggcccagg acttcatgga
     1381 gtacagttac cagggacctg gtcactgacc tcaggaaagg agtgggcctt tctaacacaa
     1441 aagctgtcaa gccaaccaaa atcatgccca aaaaagtggt taggttgatt gcaaagggga
     1501 aggggttcct ggacaacatt accatctcaa ccacagccca catggctgca ttctttgctg
     1561 ctagtgactg gctagtgagg aaccaggatg agaaaggtgg ctggccaatt atggtgaccc
     1621 ggaagttagg ggaagggttt aaatctttag agccaggatg gtactctgcc atggcacaag
     1681 ggcaagccat ctctacctta gtcagggcct accttctaac aaaagactat gtattcctca
     1741 attcagcttt aagggcaaca gccccataca agtttctgtc agagcagcat ggagttaaag
     1801 ccgtgttcat gaataaacat gactggtatg aagaatatcc aactacacct agctcttttg
     1861 ttttaaatgg ctttatgtat tctctgattg ggctgtatga cctaaaagaa acagcaggag
     1921 agaagcttgg gaaagaagca aggtccttgt atgagcgcgg catggaatct cttaaagcca
     1981 tgctgccctt gtatgatact ggctccggaa ccatctatga cctccgccac ttcatgcttg
     2041 gcattgctcc caacctggcc cgctgggact atcacaccac ccacatcaac cagctgcagc
     2101 tgctcagcac catcgacgag tccccaatct tcaaagaatt tgtcaagagg tggaaaagct
     2161 accttaaagg cagtagggca aagcacaact agagctcaaa accaaaagtg cgttccagcc
     2221 tcttctgagc tccagggctg agctgtgtca gcggcagagt tcagcagcac gttgcacatt
     2281 tttaaatgcg gtgtgttctg ggtttgtgag tcacagcact gtgagaagag acccttaaag
     2341 ttagtcttct gaaacagttg cattccatgg gtcaggtgct tagaaaggta ggcaaggaga
     2401 gtgcttggtc agtgcactga gcacagatgt gacctccgcc ctgctcctca tgtaggcctc
     2461 catgcagtct ctcagtcttg ggaagatgct gggaagtcac tgctgcctag cacttaccta
     2521 aaccttagca tggagtgctt ttaaaatgtg attatttata tttgtactga aagcaggctt
     2581 agaaatcagt gtgctgtgct gcaggaaaca catgcatata gcctggatcg tggactcttt
     2641 tttaaaagtg tttctttcct gtagattcat ttcttgagag ggagtgagca tttgttcaat
     2701 tatatatgga aaatattttg aattatggtt ttcttgaact atgtatatct aaacacagcc
     2761 cgtgttcagg tttcacggtc atatacataa gcacaactaa aatgaaactt gttgactgca
     2821 caagaaatta cagacatgct atgttttatg aaacttggtc tacaatcagt aaaagtttga
     2881 taatcgtctt cccacctctg ctccagtgca gtttgtcttc gtcactgtct agaaggttgc
     2941 acttcattca tttcatactg tcctttagta gttctgtctg ttgagaggac attactcaga
     3001 atattataag cctaaatttg tgacagactt aacagtttga aactaaccat tggtacttcc
     3061 tccataaaag aaaagtactg ggttaagtgt catgttcagg agtcacagta aagttttcca
     3121 tgcctgggtt gtccccattg cttttcacgt catggcttct gtcctcacta tttctctgaa
     3181 gcttaatttt aaatgattcc agcattgaaa cagaagagat gctacttact atgtctgctg
     3241 tctgtgtgcc atcagatctg tcagagtcct catgctatgg acagtgtctg tggtaaggct
     3301 tcaggcatta gataaaagca acagggattg gttttgctct ggtatttgtt taagggtgtg
     3361 ataatatgga gacaattggg taacatgagc ctcacacttt ctagggacaa acagtggagc
     3421 ttatccatgc tgttggtcag atgcacgttt aagatggggt ggatgatcca cccacacaca
     3481 ttgtacttct actgaattca gctaaaaagt gctgttgaaa actggagtgc ataaacgcgc
     3541 acgcacatgt atacataatg atacatatgt aaactacatt aacatcaaag gctggaaaga
     3601 aggtctgtac tgaagacaat attaaactgt tgagaagtaa acttagactc ccggtttata
     3661 tgaccacacc ttaattttac ctacaacgta actagcgtgg tcattaggtt ccccagtttt
     3721 tacctctggt tctcacacac taggtgtttc agcaacatct gaacatgcac attttgtctc
     3781 agcaataaaa acgaagactc cctttttcag tacctatgtt caaaacaagc ttgcccacct
     3841 gggaacactg ttcactacag atttgtcact ggagtgctcc caactctgct ttctgtttgc
     3901 atactggtct tcagatgaga ggagtcagtg aatcctggaa ctgatttttg tgacaaacac
     3961 cagtgcctta ccaatgtggt tgtccttttt gtttctgttt ctgtttctga ggtagagatg
     4021 gcagttcact gctgttgcat ttccactgcc ttccacattg caacagccac ttgacttgtt
     4081 tgtgatccca gaattcccta agaggtcaca cagagcctgt gatagcactg tcagtgcttg
     4141 gcttgtcaga catgaggatg cctctgttgt cacttggcgg ttaacagaat gagactctgg
     4201 ctgcaggaag tctgcctgtg aggtggggat ccactgcatg ttgacaggtg ggagaaccgg
     4261 gcatgtgtga aggaacactg cctgggaccc atgcaatttt gcttccagaa aacttcaaag
     4321 tttcctaggt ttttaaatca tgtgtttact tatcctgagt atggagagaa tggggagggt
     4381 attttaaatt tttattgtga ctctttaact tttttcttta aaggtaatgg tttggttcac
     4441 ttatctgagt tagcttccat gttgaatctt ttgccatttc agtagtaaaa cagccaaaag
     4501 tttctagcaa agggcagatt tgacccttta ggagttactg tatataacag cttcattcaa
     4561 gaaccacaca gcatctgtga gcaagtgcag aagtgacacc gcaccctcca gatgcaggcc
     4621 tctgtctttg ttagtgtaca gactcttacc aaaagctgct gctttgttct tgtgattgtt
     4681 tccttgcttc tccattgtac atgtggggta tatgccatgt gtcaaatatg caataatgtg
     4741 tttaccggat gcccttctgc agggtggtcc tctgtaaagc tgtacagcct ttgcagttca
     4801 agcacaatgt gcacatgtta gttttatata cagcaaaact tgattttttc aaatggaaag
     4861 gtattttttg tttctataca aagttaaatg ggttgtttgt gcttaatgta aagctgcttt
     4921 ataaaattgt aaaataaagt ttttatctca aaaagaaa
//
