LOCUS       NM_198972                706 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus gastrokine 1 (Gkn1), mRNA.
ACCESSION   NM_198972 XM_216210
VERSION     NM_198972.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Oien KA, McGregor F, Butler S, Ferrier RK, Downie I, Bryce S, Burns
            S and Keith WN.
  TITLE     Gastrokine 1 is abundantly and specifically expressed in
            superficial gastric epithelium, down-regulated in gastric
            carcinoma, and shows high evolutionary conservation
  JOURNAL   J Pathol 203 (3), 789-797 (2004)
   PUBMED   15221938
REFERENCE   2  (bases 1 to 706)
  AUTHORS   Martin TE, Powell CT, Wang Z, Bhattacharyya S, Walsh-Reitz MM,
            Agarwal K and Toback FG.
  TITLE     A novel mitogenic protein that is highly expressed in cells of the
            gastric antrum mucosa
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 285 (2), G332-G343 (2003)
   PUBMED   12851218
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY456958.1.
            
            On Dec 17, 2003 this sequence version replaced XM_216210.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY456958.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN13663606,
                                           SAMN13663612 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..706
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /note="gastrokine 1"
                     /db_xref="GeneID:297418"
                     /db_xref="RGD:735014"
     exon            1..50
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..590
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /codon_start=1
                     /product="gastrokine-1 precursor"
                     /protein_id="NP_945323.1"
                     /db_xref="GeneID:297418"
                     /db_xref="RGD:735014"
                     /translation="MGFTVLIVGLLGLLAAPGFAYTININGDSNVDGSGQQSVSINGV
                     HNVANIDNNNGWDSWNSLWDYENSFAATRLFAKKSCIVHKMNKDAMPSLQDLDTLVKQ
                     QKGKGPEGASPKDLMYSINPTRVEDVNTFGPKIASMCRGIPTYVAEEIPGPNQPLYSK
                     KCYTANILWILRMSFCETSVETY"
     exon            51..101
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /inference="alignment:Splign:2.1.0"
     exon            102..239
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /inference="alignment:Splign:2.1.0"
     exon            240..350
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /inference="alignment:Splign:2.1.0"
     exon            351..492
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /inference="alignment:Splign:2.1.0"
     exon            493..706
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      684..689
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gkn1"
                     /gene_synonym="Amp18; Ca11; Fov; foveolin"
ORIGIN      
        1 atgcctgcct gctcctccac tccaccactg ctgtcgacat ggggttcaca gtcctcatcg
       61 ttggtctgct cgggctcctc gcagctcctg gctttgctta cactatcaac atcaatggtg
      121 acagcaatgt agacggaagt ggacagcagt cggtgagcat caacggtgtg cacaacgtgg
      181 ccaatattga caacaataac ggctgggact cctggaacag cctctgggac tatgaaaata
      241 gttttgctgc aacgagactc tttgccaaga aatcatgcat tgtgcacaaa atgaataagg
      301 acgccatgcc ctcccttcag gacctcgata cactggtcaa gcagcaaaag ggtaaagggc
      361 ccgagggagc atctcccaag gacttgatgt actccatcaa ccctaccaga gtggaggacg
      421 tgaatacatt cgggccgaag attgctagca tgtgccgggg catccctacc tatgtggctg
      481 aggagattcc aggaccaaac cagcctttgt actcaaagaa gtgctacaca gctaacatac
      541 tctggattct gcgcatgtcc ttctgtgaaa catcagtgga aacatactag aagtcacaga
      601 aagacaaaat gtgggctctg accattgcaa tacctaatta tgagaatgtt ctcggagagt
      661 tatgattagc ttctttaagg ttcaataaac ccacctggca gcacaa
//
