LOCUS       NM_019241               1300 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus gap junction protein, beta 5 (Gjb5), mRNA.
ACCESSION   NM_019241 XM_008763990
VERSION     NM_019241.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Kibschull,M., Colaco,K., Matysiak-Zablocki,E., Winterhager,E. and
            Lye,S.J.
  TITLE     Connexin31.1 (Gjb5) deficiency blocks trophoblast stem cell
            differentiation and delays placental development
  JOURNAL   Stem Cells Dev 23 (21), 2649-2660 (2014)
   PUBMED   24866916
REFERENCE   2  (bases 1 to 1300)
  AUTHORS   Zheng-Fischhofer,Q., Kibschull,M., Schnichels,M., Kretz,M.,
            Petrasch-Parwez,E., Strotmann,J., Reucher,H., Lynn,B.D., Nagy,J.I.,
            Lye,S.J., Winterhager,E. and Willecke,K.
  TITLE     Characterization of connexin31.1-deficient mice reveals impaired
            placental development
  JOURNAL   Dev Biol 312 (1), 258-271 (2007)
   PUBMED   17961533
REFERENCE   3  (bases 1 to 1300)
  AUTHORS   Dufresne,J., Finnson,K.W., Gregory,M. and Cyr,D.G.
  TITLE     Expression of multiple connexins in the rat epididymis indicates a
            complex regulation of gap junctional communication
  JOURNAL   Am J Physiol Cell Physiol 284 (1), C33-C43 (2003)
   PUBMED   12388089
REFERENCE   4  (bases 1 to 1300)
  AUTHORS   Haefliger,J.A., Bruzzone,R., Jenkins,N.A., Gilbert,D.J.,
            Copeland,N.G. and Paul,D.L.
  TITLE     Four novel members of the connexin family of gap junction proteins.
            Molecular cloning, expression, and chromosome mapping
  JOURNAL   J Biol Chem 267 (3), 2057-2064 (1992)
   PUBMED   1370487
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On or before Aug 30, 2022 this sequence version replaced
            XM_008763990.2, NM_019241.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.23763.1,
                                           SRR26643299.24336.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN09345238, SAMN09345329
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               JAXUCZ010000005.1  144967915-144968051 c
            138-1300            JAXUCZ010000005.1  144965133-144966295 c
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1300
                     /gene="Gjb5"
                     /gene_synonym="Cx31.1; Cxna"
                     /note="gap junction protein, beta 5"
                     /db_xref="GeneID:29586"
                     /db_xref="RGD:2696"
     exon            1..137
                     /gene="Gjb5"
                     /gene_synonym="Cx31.1; Cxna"
                     /inference="alignment:Splign:2.1.0"
     exon            138..1300
                     /gene="Gjb5"
                     /gene_synonym="Cx31.1; Cxna"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..977
                     /gene="Gjb5"
                     /gene_synonym="Cx31.1; Cxna"
                     /note="gap junction membrane channel protein beta 5;
                     connexin-31.1; connexin a"
                     /codon_start=1
                     /product="gap junction beta-5 protein"
                     /protein_id="NP_062114.1"
                     /db_xref="GeneID:29586"
                     /db_xref="RGD:2696"
                     /translation="MNWSVFEGLLSGVNKYSTAFGRIWLSLVFVFRVLVYLVTAERVW
                     GDDQKDFDCNTRQPGCTNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYRKARE
                     KKYQQEVGKGYLYPNPGKKRGGLWWTYVCSLLFKATIDIIFLYLFHAFYPRYTLPSMV
                     KCHSAPCPNTVDCFIAKPSEKNIFIVFMLVTAIVCILLNLVELLYLVIKRCSECAPAK
                     RPPTAHAKNDPNWANPSSKEKDFLSSDLIFLGSDTHPPLLPDRPRAHVKKTIL"
ORIGIN      
        1 gctcagcagc ctctgcccca actatgagct ttaccagaaa cccttgcctg attctgacat
       61 gaattttgat gcttgctgaa ccccaactgc tagcttccag gagcggtact agggagccat
      121 aaggagtcgc tgctcaggag caaccagccc ttgagtccac catgaactgg agcgtctttg
      181 aggggctcct aagtggggtc aacaagtact ccacagcctt tggtcgcatc tggctgtctc
      241 tggtctttgt cttccgtgtg ctggtgtacc tggtgacagc cgagcgtgtg tggggtgacg
      301 accagaagga ctttgactgc aacactaggc aacccggctg taccaacgtc tgctatgatg
      361 agttcttccc tgtgtcccac gtgcgcctct gggccctgca gctcatcctg gtcacatgcc
      421 cctccttgct tgtcgtcatg catgtggcct atagaaaggc tcgagagaag aagtaccagc
      481 aagaagttgg caaagggtac ctctacccaa accccggcaa gaagcgaggc ggactctggt
      541 ggacatacgt ctgcagcctg ttgttcaagg ccaccataga tattattttc ctctaccttt
      601 tccatgcatt ctaccccaga tataccctcc cgtctatggt caagtgccat tcggcaccat
      661 gtcccaacac agtggactgc ttcatcgcca agccctcaga gaagaacatc ttcattgtct
      721 tcatgttggt cacggccatc gtctgcatcc tgcttaacct tgtggagctg ctctacttgg
      781 tgatcaagcg gtgttctgag tgtgcaccag cgaagagacc gcccactgca cacgcaaaga
      841 atgacccaaa ctgggccaac ccttccagca aagagaagga cttcctctca agcgacctca
      901 tctttctggg ctcggacact cacccacctc tgttacctga tcgccctcga gcccacgtga
      961 agaaaaccat tctgtgaagg gtccctagac tggactggcg gggtgggcat gaactggaag
     1021 gttccagaat ctctcatgaa tgtagctggt gaggaaaaga gctgagtcgg agttggaggc
     1081 agacaaaagg gaggactccc agagcttggg atccaactgt ccctcctggc tgactggtct
     1141 tcgctgaaac cctctactct gaacctcagt ttccttttct gttaaataaa cacactgagt
     1201 gccacttaac agggctgggg gtggatgaga gcacagatga gcaaacgcct tcctgtgtga
     1261 cccagggtga gaactcaata aagataaatg tgttcacaga
//
