LOCUS       XM_039101769            3947 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus growth hormone receptor (Ghr),
            transcript variant X2, mRNA.
ACCESSION   XM_039101769
VERSION     XM_039101769.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039101769.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3947
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3947
                     /gene="Ghr"
                     /gene_synonym="GHR/BP"
                     /note="growth hormone receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 80 ESTs, 6 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     7 samples with support for all annotated introns"
                     /db_xref="GeneID:25235"
                     /db_xref="RGD:2687"
     CDS             48..1964
                     /gene="Ghr"
                     /gene_synonym="GHR/BP"
                     /codon_start=1
                     /product="growth hormone receptor isoform X1"
                     /protein_id="XP_038957697.1"
                     /db_xref="GeneID:25235"
                     /db_xref="RGD:2687"
                     /translation="MDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLR
                     ESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECP
                     DYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLL
                     NISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLY
                     SLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGI
                     FGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYK
                     PDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYD
                     PDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITL
                     TMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIK
                     AGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIY
                     ITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSS
                     CGYVSTDQLNKIMQ"
ORIGIN      
        1 aaaaaaaaag aaagtccgtt tcttgtcagt gatgcacagt ctcaggtatg gatctttggc
       61 gggtgttctt aaccctggca ctggcagtct ccagcgacat gtttcctgga agtggggcta
      121 caccagctac tcttggcaaa gcttccccgg ttctgcaaag aattaatcca agcctgaggg
      181 aaagttcctc tggaaagcct cgattcacca agtgtcgttc ccctgaactg gagacctttt
      241 catgctactg gacagaaggg gatgatcata atttaaaggt cccgggatct attcagctat
      301 actatgctag aagaattgct catgaatgga ccccggaatg gaaagaatgc cctgattatg
      361 tctctgctgg agcaaacagc tgttacttca actcatcgta tacctccatt tggataccct
      421 actgcattaa gcttactaca aatggtgatt tgttggacga aaagtgtttc actgttgatg
      481 aaatagtgca acctgatccg cccattggcc tcaactggac tttactaaac atcagtttgc
      541 ctgggatccg tggagatatc caagtgagtt ggcagccacc gcccagtgcc gatgttctga
      601 agggatggat aattctggag tatgaaattc agtacaaaga agtaaatgaa acaaaatgga
      661 aaacgatgag cccgatatgg tcaacatcag tcccactgta ctcactgaga ctggataaag
      721 agcacgaagt gcgtgtgaga tccagacaac ggagcttcga aaagtacagc gagttcagtg
      781 aagtactccg tgtaacgttt cctcagatgg acacactggc agcatgtgaa gaagatttcc
      841 ggtttccatg gttcttaatt attatctttg gaatatttgg agtagcagtg atgctatttg
      901 tagttatatt ttcaaagcag caaaggatta agatgctgat tttaccccca gtaccagttc
      961 caaagattaa agggattgat ccagatcttc tcaaggaagg aaaattggag gaggtgaaca
     1021 ccatcttggg cattcatgat aactacaaac ccgacttcta caatgatgac tcctgggttg
     1081 agttcattga gctggatatt gatgatgcgg atgagaagac tgaagagtca gacaccgaca
     1141 gacttctaag cgatgaccag gagaaatcag ctggtatcct tggagcaaag gatgacgatt
     1201 ctggacgtac cagctgttat gaccctgaca ttttggatac cgatttccac accagtgaca
     1261 tgtgcgatgg tacctcggag tttgctcagc cgcagaagtt aaaagcagaa gctgatctct
     1321 tgtgccttga ccagaagaat ctgaagaact cgccttatga tgcttccctt ggctctctgc
     1381 acccctccat taccctgaca atggaagaca aaccacagcc acttctgggc agtgaaactg
     1441 agtcaaccca ccaactcccc tctacaccaa tgagcagtcc cgtgtcactg gcaaacattg
     1501 acttttatgc ccaagtaagc gacattacac cagcaggtgg tgtagtcctt tctccaggcc
     1561 aaaagattaa ggcagggtta gcccagggca acacccagct ggaggtggcc gcgccctgcc
     1621 aagaaaatta cagcatgaac agtgcctact tctgtgagtc agatgccaaa aagtgcatcg
     1681 ctgcggcccc tcacatggag gccacgacat gtgtaaaacc aagctttaac caagaggaca
     1741 tttacatcac cacagaaagc cttaccacta ctgcccgaat gtccgagaca gcagataccg
     1801 ctccagatgc tgagcctgtc ccagactaca ccacggttca caccgtgaag tccccaaggg
     1861 gccttatact caacgcgact gctttgcctt tgcctgacaa aaagaagttt ctctcctcat
     1921 gtggctatgt gagcacagac caactgaaca aaatcatgca gtagcctttc ctatctttaa
     1981 tggcaaaaga aatgactggg cacgaacgcc taaaccaaaa ctatgtttta aatctgtgtt
     2041 gggagagcgt gagagtgaat gtggattcaa aaataccttt tctggaaacg tcgaaacatt
     2101 atcataacgt ggaaaatcaa gaatatgtaa tcagatagat actcccattg tgaattttaa
     2161 atattttaaa gaatcgtctt taagactgtt tagtggcagt gattgtctgt gctgtgggtc
     2221 ttaactttgt gatactaagt attaaatagc tacgtttttc atgtatgtag atcatgcttt
     2281 tttgaaaaag caaaacaatc aggtggcttt tgcagttcag gaaattgaat gcagatttta
     2341 gcacagactg atttcttttt cctttttaaa tagctaggag ctaaaactct aggggagaag
     2401 gtaaaactag tttggatatg caaaacattt attttgacat aaaattgata aagatatttt
     2461 taataattta cactgtaagc atgagtattt tataatacac tacagatata ttgtagttca
     2521 caacaatcca tctacggatg taacaactac aatgtgtaga ggggttgatg ctttggtcaa
     2581 tgaacctaaa gaaaaatgaa caagttagat ttttacaaag ccctttttta taactcccaa
     2641 aacttcttaa atctaaaaat gtctgcatta ttggaacaaa cccattttaa atttgtaaat
     2701 gaatattttt ttaattttga aaactttaat tttttataca aattaacgta tcatacacca
     2761 aacagtaaca gaagtgatta taataatgga agaaacagtt tcttcaccaa atttccattc
     2821 aagccacaag gctgtgtgta agagaagtag aagtgatgtg gtgtgactgg ctaggataaa
     2881 ggagatcttc aggagcacat gggtttagag agcccaggga tcaggaaaag gaggctctca
     2941 catctgagca gtgctgtcct ttcaaacaca gcttggcttt tatagtaacc taagaattaa
     3001 tgcatacaag gaggagtttc acatgtgtga aatccaatag cagatgggtt aaagttaaac
     3061 aagttatagc acaggaaatt aaagacctag atctttgttt cgcagtcaga cacatacttt
     3121 taattcaggg agaaaaggga cagaataaat gacttcacag tcacaaggca cacctcagaa
     3181 gtagttaaac aagtaacaga aaccttgtta tcaaaccttt aataagatgt attttaaata
     3241 gtaagcagta tttcattgct tcttaccctc ccagagagat tgatctcaaa taaggtagga
     3301 aaacaaacaa tataaaaatc actttaatta tgtaataaca tagacacagc tctttgggtt
     3361 agccccccaa aagatttatg agagaaggag gactttcagc caactgaaga atacttctca
     3421 ttttaagcac tttttagatg cttgaaactt taaaattacc tttaactttc aatgatattt
     3481 accattttgc agagaccttt gtggggaaac aggcttaatg tttagtggtt tttaaatctc
     3541 tttcatgcag gagagacagt gaaaaattta gacttgggtg tttaaggttc actgtgttat
     3601 tctgtagtag attttaatag atttttttct gctaccttgc tgctatggtt tccccaatgg
     3661 ctacatgatt tagttcatat gaagtatcat caacttagaa cctattcagc ttaaagatgt
     3721 gtgttttgat gaactatctt accatttcac cataggctga ccacgttgct atagccaaaa
     3781 atagctaaat acctcaatca gtcccagaat gtcatttttg gtactttgct ggccacacaa
     3841 gccattattc accatgtgac tagttgtgtc ctgcagtctg tatttaactt tcttttatgt
     3901 ctgtggattt ttcccttcaa agttcaataa atttattttc ttggact
//
