LOCUS       NM_130423               2589 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus gamma-glutamyltransferase 7 (Ggt7), mRNA.
ACCESSION   NM_130423
VERSION     NM_130423.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Bui,T.T., Nitta,R.T., Kahn,S.A., Razavi,S.M., Agarwal,M., Aujla,P.,
            Gholamin,S., Recht,L. and Li,G.
  TITLE     gamma-Glutamyl transferase 7 is a novel regulator of glioblastoma
            growth
  JOURNAL   BMC Cancer 15, 225 (2015)
   PUBMED   25884624
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2589)
  AUTHORS   He,X., Di,Y., Li,J., Xie,Y., Tang,Y., Zhang,F., Wei,L., Zhang,Y.,
            Qin,W., Huo,K., Li,Y., Wan,D. and Gu,J.
  TITLE     Molecular cloning and characterization of CT120, a novel
            membrane-associated gene involved in amino acid transport and
            glutathione metabolism
  JOURNAL   Biochem Biophys Res Commun 297 (3), 528-536 (2002)
   PUBMED   12270127
REFERENCE   3  (bases 1 to 2589)
  AUTHORS   Yamaguchi,T., Takei,N., Araki,K., Ishii,K., Nagano,T., Ichikawa,T.,
            Kumanishi,T. and Nawa,H.
  TITLE     Molecular characterization of a novel gamma-glutamyl transpeptidase
            homologue found in rat brain
  JOURNAL   J Biochem 128 (1), 101-106 (2000)
   PUBMED   10876163
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB761916.1, AF244973.1 and AA925130.1.
            
            On Oct 8, 2008 this sequence version replaced NM_130423.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF244973.1, SRR8487231.46541.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                CB761916.1         1-17
            18-2134             AF244973.1         1-2117
            2135-2589           AA925130.1         1-455               c
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2589
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /note="gamma-glutamyltransferase 7"
                     /db_xref="GeneID:156275"
                     /db_xref="RGD:619870"
     exon            1..181
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..2001
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /EC_number="2.3.2.2"
                     /EC_number="3.4.19.13"
                     /note="GGT 7; gamma-glutamyltranspeptidase 7;
                     gamma-glutamyltransferase-like 3"
                     /codon_start=1
                     /product="glutathione hydrolase 7"
                     /protein_id="NP_569107.2"
                     /db_xref="GeneID:156275"
                     /db_xref="RGD:619870"
                     /translation="MAAENEASQESALGAYSPVDYMSITSFPRLPEDEPAPAAPLRGR
                     KDEDAFLGDPDTDPDSFLKSARLQRLPSSSSEMGSQDGSPLRETRKDPFSAAAAECSC
                     RQDGLTVIVTACLTFATGVTVALVMQIYFGDPQIFQQGAVVTDASCCTALGMEVLSKQ
                     GSSVDAAVAAALCLGIVAPHSSGLGGGGVMLVHDIRRNESHLIDFRESAPGALREEAL
                     QRSWDTKPGLLVGVPGMVKGLYEAHQLYGRLPWSQVLAFAAAVAQDGFNVTHDLAHAL
                     AEQLPPNASDRFLETFLPLGHPPLPGSLLRRPDLAEVLDILGISGPAAFYNGGNLTLE
                     MVAEVQHAGGVMTEEDFSNYSALTEKPVCGVYRGHLVLSPPPPHTGPALISALNILEG
                     FNLTSLVSREQALHWVAETLKIALALASRLGDPVYDSTISESMDDMLSKVEAANFRGH
                     ISDSQAAPAPLLPVYELDGAPTAAQVLVMGPDDFIVAMVSSLNRPFGSGLLTPSGILL
                     NSQMLDFSWPNRTANHSAPSLENSVQPGKRPLSFLLPTVVRPAEGLCGTYLALGANGA
                     ARGLSGLTQVLLNVLTLNRNLSDSLARGRLHPDLQSNVLQVDSEFTEEEIEFLEARGH
                     HVEKVDVLSWVHGSRRTNNFIIGVKDPRSLDATGASIL"
     exon            182..417
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            418..569
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            570..687
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            688..755
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            756..829
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            830..1026
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1114
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1242
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1331
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1481
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1599
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1737
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1837
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..2574
                     /gene="Ggt7"
                     /gene_synonym="Ggtl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttagggcga ggatggcggc agagaacgag gctagccagg agagcgccct aggcgcctac
       61 tcaccagtag actacatgag catcaccagc ttcccgaggc tgcccgagga cgagccagcg
      121 cctgcggccc cgctgagggg ccgtaaggac gaggatgcct tcctgggaga cccggatact
      181 gatccggact ccttcctgaa gtctgcccgg cttcagcgat tgccttcatc ttcctcggag
      241 atgggcagcc aggacgggtc accacttcgc gagacgcgca aggacccatt ctcagctgca
      301 gcagccgagt gttcctgccg ccaggacggg ctcacggtca tcgtcaccgc ctgcctcact
      361 tttgccacgg gtgttaccgt ggcgctggtc atgcaaatct acttcgggga tccccagatc
      421 ttccagcaag gtgctgtggt gacggatgcc tcctgttgca cggcgctggg catggaggtg
      481 ctcagtaaac agggctcttc cgtggacgca gctgtggcag cagccttgtg tttgggaata
      541 gtggctccac acagttctgg cctgggcggg ggaggcgtga tgctggtaca cgatatccgc
      601 cggaatgaga gccacctaat tgatttccgg gagtctgcac ctggggccct cagagaagag
      661 gccctgcaga gatcctggga taccaagcct gggctcttgg tgggggtccc cggaatggtg
      721 aaagggctat atgaagctca tcaactctat ggcaggctgc cctggtccca agtcctggcc
      781 ttcgcagcag ctgtggccca agatggcttc aacgtgaccc atgatctagc tcatgccttg
      841 gctgagcagc tgcctcccaa tgcatctgac cgcttcctgg aaactttcct gccgttgggc
      901 cacccacctt tgcctggctc cctgctgaga cggcctgatc tcgccgaggt gctggatata
      961 cttggcatct ctggccctgc tgccttctac aatggtggca acctcacgct ggagatggtg
     1021 gctgaggttc agcatgcagg gggtgtcatg accgaggagg acttcagcaa ctatagtgct
     1081 ctcacggaga agcctgtgtg tggagtatac cgaggccacc tggttctcag tcccccaccc
     1141 ccacacacag gcccggccct catcagtgcg ctcaacatcc tggagggctt caacctcacc
     1201 agcctggtat cccgcgagca agcgcttcac tgggtagcag agaccctgaa gattgcattg
     1261 gccctggcta gcagactggg agaccctgtc tatgattcta ccatcagtga gagcatggac
     1321 gacatgctca gcaaggtgga ggctgccaac ttccggggcc acatcagtga ctctcaggca
     1381 gcccctgccc cactcctgcc tgtctatgag ctggacgggg ctcccacagc tgcccaggtg
     1441 ctggtcatgg gccctgacga cttcatcgtg gccatggtca gctccctgaa tcggcctttt
     1501 ggaagtggcc tcctcactcc ctccgggatc cttctcaaca gccagatgct agacttctcc
     1561 tggcccaata ggactgctaa ccactctgca cccagcctgg agaactcggt acagccaggg
     1621 aagcggcccc tctctttcct tctgcccact gtagtccgac cagcagaagg gctctgtggg
     1681 acctacctcg ctctgggggc caacggagct gctcgaggcc tcagtggcct gacccaggtt
     1741 ctactgaatg tcctgacctt gaatcggaac ctgagtgaca gcctggccag aggacgcctc
     1801 cacccagacc tgcagtccaa cgtcctgcag gtggacagtg agttcaccga ggaagagatt
     1861 gagttcctgg aagccagggg tcaccatgtg gagaaggtag atgtcttatc ctgggtccac
     1921 ggcagtcgga gaaccaacaa cttcatcatt ggtgtgaagg accctcggag cctggatgca
     1981 accggagcca gcatcctgta gagcattggg gtgggcggga cctctgctcc ccgcctttgc
     2041 atgttcccag agtccctctc tctcccaggt ttggtctcag ggggacccca tggatgcctc
     2101 agatcagggg ccagagggga tgcttagcaa accctatccc agagtaactg gaaaattctc
     2161 caactggagg cctttggcgg taatgatgac atcagtgtcc atgaccaggc agacaggacc
     2221 ttgaggagtc agattgtctg tccgcctctt ctcctctctc agccatgcta tccttgagct
     2281 tagggatgtg cttgcaaacc cttctcaagg gtctcacaac cccaacacct tcagactggt
     2341 ctgacccagg ccttgtcttc cagctccctt ttcctgtatc tggccccgtt tcttaagtga
     2401 ctaggatttt tttttaaatt ggccactata gggagaggta atcctcccct tccaccaggt
     2461 tgaagcaggg gccttgcatt tgcaggttcc caggcagccg agtaggggtg ggggtgggta
     2521 tcagctcagg ggcttccatt tgcaatgggg aattaaagaa agaatattgc ttaaaaaaaa
     2581 aaaaaaaaa
//
