LOCUS       NM_001002820            1943 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus gamma-glutamyl transferase 6 (Ggt6), mRNA.
ACCESSION   NM_001002820 XM_579088
VERSION     NM_001002820.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1943)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 31, 2022 this sequence version replaced NM_001002820.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BN000385.1, SRR26643294.40193.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000010.1  57550538-57550725
            189-391             JAXUCZ010000010.1  57551330-57551532
            392-505             JAXUCZ010000010.1  57551610-57551723
            506-1943            JAXUCZ010000010.1  57552024-57553461
FEATURES             Location/Qualifiers
     source          1..1943
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1943
                     /gene="Ggt6"
                     /note="gamma-glutamyl transferase 6"
                     /db_xref="GeneID:408206"
                     /db_xref="RGD:1303335"
     exon            1..188
                     /gene="Ggt6"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1545
                     /gene="Ggt6"
                     /EC_number="2.3.2.2"
                     /EC_number="3.4.19.13"
                     /function="threonine peptidase"
                     /note="gamma-glutamyltransferase 6; GGT 6;
                     gamma-glutamyltranspeptidase 6"
                     /codon_start=1
                     /product="glutathione hydrolase 6"
                     /protein_id="NP_001002820.1"
                     /db_xref="GeneID:408206"
                     /db_xref="RGD:1303335"
                     /translation="MDATTGAVLYQKLQLWEPGMESEEEEEEEEIAEPLVLSLRRLQN
                     TPGNKVGGLPGAWTRLLAGLLLLAVSSSLALRQLQGRNSPKGNLGPVDLPASRHSHHP
                     GVYHHSAVISPAATCSRLGQELLVAGGNVVDAGVGAALCLAVVHPHATGLGATFWGLF
                     YNSSSGNSTALTAGPAQILAPGLGLPTALPALHLLHTHFGRLPWSHLLAKPAMLAQKG
                     FEVDAPLASALAAQGTEGLCPLFCHTNGTPLGLGAQVTNPNLAAVLLREALASSPDLV
                     GNALLNLLVRDLGLELPSVQPKPSLEPALQLLLPQGVLFTTPGPSAGPELMGLLESTL
                     HSKTPSPASCSSLLQTAETPVSSALATVDSHGSMLLLTSSLNSSFGSGHLSPSTGVLL
                     SNLEASSVPSTWACPLILRGNLDDTEDDMLGLVASGIPRGAKAMACTLFNHLTTPQTQ
                     QQVQHQAQQRPTESPGICGKEALLQVVVHAEHAQVSSIPSGCCPFQGY"
     exon            189..391
                     /gene="Ggt6"
                     /inference="alignment:Splign:2.1.0"
     exon            392..505
                     /gene="Ggt6"
                     /inference="alignment:Splign:2.1.0"
     exon            506..1943
                     /gene="Ggt6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtctcaact gtcagggctc tcggtaaaga tctggggaag cacgggccat ggatgccacc
       61 acaggggctg tgctctacca gaagctgcaa ctctgggagc ctggcatgga gtcagaggag
      121 gaggaagaag aggaagaaat agcagaacca ctagtccttt ccctaaggag actccaaaat
      181 acccccggga acaaggttgg tgggttgcca ggagcctgga cccgcctgct ggcaggcctg
      241 ctgctgctgg ctgttagcag ctccctggct ctgaggcagc tgcaaggtag gaacagccca
      301 aaaggaaact tgggccctgt ggatcttcca gccagcagac actcccacca ccctggtgtg
      361 taccaccaca gcgctgtcat cagccctgca gccacatgtt cccgactggg ccaagagctg
      421 cttgtcgctg ggggcaatgt cgtggatgct ggagttggag cagctttgtg tctggcggtg
      481 gtgcatcctc atgcaacagg gctaggtgcc acattctggg gtctcttcta caatagctcc
      541 tcaggaaact caactgccct gacagcaggt ccagcccaaa tcctggcccc tggcctggga
      601 ctgcccacag ctctgcctgc cctgcatttg cttcataccc acttcggccg cctgccctgg
      661 tcacacctgc tggccaagcc tgccatgctg gctcaaaagg gctttgaggt agatgcaccc
      721 ctggcaagcg cactagcagc ccagggtaca gaggggctct gtccactgtt ctgccatacc
      781 aacggaaccc cactgggtct tggggctcaa gtcaccaacc ccaacctggc agctgtgttg
      841 ctccgtgaag ccctggcctc cagcccagat cttgttggga atgccttgct gaacctgctg
      901 gtcagagacc tggggttaga gttgccctct gtgcagccca agccttcctt agagcctgca
      961 ctgcagcttc ttctgcctca gggtgtgctg ttcactactc ctggcccctc agcaggccca
     1021 gaacttatgg gactgttgga gtctactctt cactccaaga cacccagccc tgcttcctgc
     1081 tcatcactcc tgcagactgc tgaaacccca gtgagcagtg ccctggccac tgtggacagc
     1141 catggctcca tgctccttct aacctcctca ctcaacagct cctttggctc tggacatctg
     1201 tccccaagta ctggcgttct tctcagcaac ctggaagcca gctctgtacc tagtacctgg
     1261 gcctgtccac tcattctccg tggcaaccta gatgacacag aagacgatat gttggggctg
     1321 gtggcttcag ggatccccag aggggccaaa gccatggctt gcaccttgtt caatcatctg
     1381 acaacacccc aaacccaaca gcaggtccaa catcaagccc aacaaagacc cacagaaagc
     1441 cctggcattt gtggcaaaga ggctctactg caggtagtag tccatgcaga acacgcccag
     1501 gtctccagca tccctagtgg ctgctgcccc tttcaggggt attaacagag ggtcagagat
     1561 gtctggaacc taagagccag acagagaagg cctggcagca atgaatgtat gaagagaatg
     1621 tatctgtgat gtgtttgctg ctccaacaac cctgcatcct gttacgctac ctggttctag
     1681 ctctggcatc cagggctggt ccaaccacgt ttcctggtac cctcgctgat ggaatttctg
     1741 gctttttttt ttttaaatca aataaagact tagagggtga tgaaaaagag cttgagtgca
     1801 actcaccttc aggaaagtcc ggaggagtca tcactcccta cctggtcttt gggcagggtg
     1861 gtccgctcca tcttccactg ggccattccc tgctgatctt tatcaattgg actggaagtt
     1921 aataaaactc aaatatcccg gga
//
