LOCUS       NM_001013065            2436 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Rattus norvegicus gametogenetin (Ggn), transcript variant 1, mRNA.
ACCESSION   NM_001013065 XM_214882
VERSION     NM_001013065.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2436)
  AUTHORS   Jamsai,D., O'Connor,A.E., Deboer,K.D., Clark,B.J., Smith,S.J.,
            Browne,C.M., Bensley,J.G., Merriman,J.A., Yuen,W.S., Koopman,P.,
            Jones,K.T. and O'Bryan,M.K.
  TITLE     Loss of GGN leads to pre-implantation embryonic lethality and
            compromised male meiotic DNA double strand break repair in the
            mouse
  JOURNAL   PLoS One 8 (2), e56955 (2013)
   PUBMED   23451117
REFERENCE   2  (bases 1 to 2436)
  AUTHORS   Zhang,J., Wang,Y., Zhou,Y., Cao,Z., Huang,P. and Lu,B.
  TITLE     Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are
            potential interaction partners of testicular germ cell-specific
            protein GGN1
  JOURNAL   FEBS Lett 579 (2), 559-566 (2005)
   PUBMED   15642376
REFERENCE   3  (bases 1 to 2436)
  AUTHORS   Hansson,A.S., Johannesson,M., Svensson,L., Nandakumar,K.S.,
            Heinegard,D. and Holmdahl,R.
  TITLE     Relapsing polychondritis, induced in mice with matrilin 1, is an
            antibody- and complement-dependent disease
  JOURNAL   Am J Pathol 164 (3), 959-966 (2004)
   PUBMED   14982849
REFERENCE   4  (bases 1 to 2436)
  AUTHORS   Lu,B. and Bishop,C.E.
  TITLE     Mouse GGN1 and GGN3, two germ cell-specific proteins from the
            single gene Ggn, interact with mouse POG and play a role in
            spermatogenesis
  JOURNAL   J Biol Chem 278 (18), 16289-16296 (2003)
   PUBMED   12574169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC081922.1.
            
            On Apr 20, 2005 this sequence version replaced XM_214882.2.
            
            Transcript Variant: This variant (1) represents the longer
            tanscript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081922.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2436              BC081922.1         1-2436
FEATURES             Location/Qualifiers
     source          1..2436
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2436
                     /gene="Ggn"
                     /note="gametogenetin"
                     /db_xref="GeneID:292765"
                     /db_xref="RGD:1306765"
     exon            1..2238
                     /gene="Ggn"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..2356
                     /gene="Ggn"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="gametogenetin isoform 1"
                     /protein_id="NP_001013083.2"
                     /db_xref="GeneID:292765"
                     /db_xref="RGD:1306765"
                     /translation="MQTGAVQEQPEPWSPHRTRRLTGGSFFNHSPRPSSKMGNVQSEP
                     SAGGGSRKEQASDRASDSRRTPLVEPEVTPSSPAMRLARGLGVWFPGSSGPPGLLIPP
                     ESQASSSTLPLTLELPSPVTPPPEEAAAAAVSTPPPPPVGTLLPAPSKWRKPTGTAVP
                     RIRGLLEASHRGQGDPPSLRPLPPLPRQLTEKDPVLRAPAPPPTPLEPRKQLPPAPST
                     CDPQPPSRRITLASSATSPTESQVRHSSEGQAAGGAHGEGEMARSATSESGLSLLCKV
                     TFKSGPHLSPTSSSGPLAAKASLGASGGGGLFASSGAISYAEVLKQGPQPPGATRPLG
                     EGPRAAQETEGGDGDGEGCSGPPSVPTPLARALPPPPYTTFPGSKPKFDWVSPPDGTE
                     RHFRFNGAVGGIGAPRRRTTTLSGPWGSPPPRSGQTHPSSGPRRPTPALLAPPMFIFP
                     APNNGEPVRPVPPSPQQIPPLPPPPPTPPATPPPAPPPTPQPPALPRTPILVARPPTP
                     GPGHLESALAPTPPSTLSPTAAAEQAPAPTPAPVTSQVPATTTAELSPPMPQPKIRTR
                     RNKGPRAARGVIREEGTSGDGPREPNMAPVTDSSSGGGGGGSNGTSTAGASNKGTARH
                     WPPFEVLNSCPCKCYCRHQRRHRRLPRNVSAWLSTPTNHLSEPPWVATVKLAGSLVAG
                     LEHYDLQATHST"
     exon            2239..2412
                     /gene="Ggn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catcattacc cgtgtggttt gaaactttcg gcagagaggc tggcgagact gagtcctgaa
       61 gcctggagat cccgggagtg gcaaagtgtt agggatgtga tctaagcagc caagggatca
      121 gggttgagcc tttgtacatt aagaagttag gttcgaagag taagaaccgc agccttgaga
      181 ccatggggaa ggggacgtga ccatgacgaa tcggagaact gaagacttaa gagacggggg
      241 ctgagagaat attggaggac agggcagacc aatgcagaca ggggctgtcc aagaacagcc
      301 tgagccgtgg agtcctcaca gaacccgccg actgactggt ggaagtttct ttaaccacag
      361 tccccgacct tcttcaaaaa tggggaacgt gcagtcggag ccgtccgcgg gcgggggttc
      421 ccgaaaagag caggcctcag accgcgcctc ggactctcgt aggacgcctc tggtggagcc
      481 cgaggtgacc ccctcatccc ctgccatgcg cctggctcga gggctgggcg tctggttccc
      541 tggcagttcc gggccccccg ggctcctgat acccccggag tcccaggcct catcctcaac
      601 cctgcccctg accttagaac tgccctcgcc agtgacaccc cctccagagg aggcggctgc
      661 ggcggcggtc tctacaccac ccccgcctcc cgtggggacc ctgctgcccg ccccatctaa
      721 gtggcgaaaa cccacgggca ctgcagtgcc tcggatccgc ggtcttctgg aggcgagcca
      781 tcgtggtcag ggtgaccctc cgagcctccg ccctctccca ccgctgcccc ggcaactgac
      841 cgaaaaagac ccggtcctga gggccccagc cccacctccg acgcccctgg aacctcggaa
      901 acagctaccg ccagcaccgt cgacttgtga cccgcagccc ccgagccgca gaatcactct
      961 ggcctcgtcg gccacaagcc ccacagaaag ccaggtcaga cacagcagcg agggtcaggc
     1021 ggccggggga gcccacggag agggcgaaat ggctcggtct gctacttctg agtctggcct
     1081 gagtctgctg tgtaaagtca ccttcaagtc ggggccccat ttgtccccca catcctcctc
     1141 gggcccctta gcagccaaag cctcactggg ggccagtggt ggcggaggac tgtttgcctc
     1201 ttctggggcc atctcttatg ctgaggtact gaagcaaggc ccccagcctc ctggagccac
     1261 tcgtccctta ggagagggcc ctcgtgcagc tcaggaaacc gagggtggtg acggagatgg
     1321 tgaagggtgt tctggtcccc cttcggtgcc tactccgctt gcccgggctc taccgccacc
     1381 cccttacacc accttcccag gttcaaagcc caaattcgac tgggtgagcc ctcctgatgg
     1441 cactgaacgg cacttccgat tcaatggggc tgttggggga atcggggcac cccgacggcg
     1501 gacgactacg ctctcagggc cttggggatc ccctccacca aggtcaggtc agacacatcc
     1561 aagttcaggg ccccgaaggc ccacacctgc cttgctggca ccacccatgt tcatcttccc
     1621 agcgccaaac aatggcgagc ctgttcgccc agtgcctcca agtccgcagc agatacctcc
     1681 gctgccaccg ccaccgccca caccaccagc cacgccacca ccagcaccgc cacccacacc
     1741 acagccacca gcactcccga ggacgccgat actggtggcc cgtccgccta ccccaggccc
     1801 tggccactta gagtcagcct tggctcccac ccctccctcc actttgtccc cgactgcagc
     1861 tgcggagcag gccccagccc cgacaccagc cccagtcaca tcccaagttc cagcaaccac
     1921 caccgctgag ctgtcacccc cgatgcccca gcccaagatt cgtacacgca ggaacaaagg
     1981 tccccgagcg gcccggggtg ttatccgtga agaagggact tctggagatg gccctcgaga
     2041 accgaatatg gctccggtga ctgacagcag cagtggaggg ggtggcggtg gtagcaacgg
     2101 aacctccaca gctggggcct ctaacaaggg aacagctcga cactggccgc ctttcgaggt
     2161 gcttaactcc tgtccctgca agtgctactg ccgccatcaa cgccgtcacc gacgtctgcc
     2221 acgcaacgtg tctgcctggc tgagtacacc caccaaccac ctgagtgagc caccttgggt
     2281 ggccaccgtc aagctggctg gctccctggt agctggccta gagcactacg acttgcaggc
     2341 cactcattct acctgagtgc aactgcccac tccctctgcc tcaccctcct tgccaataaa
     2401 gtacccagtc taaaaaaaaa aaaaaaaaaa aaaaaa
//
