LOCUS       NP_001013083             694 aa            linear   ROD 05-JUN-2024
DEFINITION  gametogenetin isoform 1 [Rattus norvegicus].
ACCESSION   NP_001013083 XP_214882
VERSION     NP_001013083.2
DBSOURCE    REFSEQ: accession NM_001013065.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 694)
  AUTHORS   Jamsai,D., O'Connor,A.E., Deboer,K.D., Clark,B.J., Smith,S.J.,
            Browne,C.M., Bensley,J.G., Merriman,J.A., Yuen,W.S., Koopman,P.,
            Jones,K.T. and O'Bryan,M.K.
  TITLE     Loss of GGN leads to pre-implantation embryonic lethality and
            compromised male meiotic DNA double strand break repair in the
            mouse
  JOURNAL   PLoS One 8 (2), e56955 (2013)
   PUBMED   23451117
REFERENCE   2  (residues 1 to 694)
  AUTHORS   Zhang,J., Wang,Y., Zhou,Y., Cao,Z., Huang,P. and Lu,B.
  TITLE     Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are
            potential interaction partners of testicular germ cell-specific
            protein GGN1
  JOURNAL   FEBS Lett 579 (2), 559-566 (2005)
   PUBMED   15642376
REFERENCE   3  (residues 1 to 694)
  AUTHORS   Hansson,A.S., Johannesson,M., Svensson,L., Nandakumar,K.S.,
            Heinegard,D. and Holmdahl,R.
  TITLE     Relapsing polychondritis, induced in mice with matrilin 1, is an
            antibody- and complement-dependent disease
  JOURNAL   Am J Pathol 164 (3), 959-966 (2004)
   PUBMED   14982849
REFERENCE   4  (residues 1 to 694)
  AUTHORS   Lu,B. and Bishop,C.E.
  TITLE     Mouse GGN1 and GGN3, two germ cell-specific proteins from the
            single gene Ggn, interact with mouse POG and play a role in
            spermatogenesis
  JOURNAL   J Biol Chem 278 (18), 16289-16296 (2003)
   PUBMED   12574169
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC081922.1.
            
            On Jun 16, 2015 this sequence version replaced NP_001013083.1.
            
            Transcript Variant: This variant (1) represents the longer
            tanscript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081922.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     Protein         1..694
                     /product="gametogenetin isoform 1"
                     /calculated_mol_wt=71445
     Region          38..693
                     /region_name="GGN"
                     /note="Gametogenetin; pfam15685"
                     /db_xref="CDD:434857"
     CDS             1..694
                     /gene="Ggn"
                     /coded_by="NM_001013065.1:272..2356"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:292765"
                     /db_xref="RGD:1306765"
ORIGIN      
        1 mqtgavqeqp epwsphrtrr ltggsffnhs prpsskmgnv qsepsagggs rkeqasdras
       61 dsrrtplvep evtpsspamr larglgvwfp gssgppglli ppesqassst lpltlelpsp
      121 vtpppeeaaa aavstppppp vgtllpapsk wrkptgtavp rirglleash rgqgdppslr
      181 plpplprqlt ekdpvlrapa ppptpleprk qlppapstcd pqppsrritl assatsptes
      241 qvrhssegqa aggahgegem arsatsesgl sllckvtfks gphlsptsss gplaakaslg
      301 asgggglfas sgaisyaevl kqgpqppgat rplgegpraa qeteggdgdg egcsgppsvp
      361 tplaralppp pyttfpgskp kfdwvsppdg terhfrfnga vggigaprrr tttlsgpwgs
      421 ppprsgqthp ssgprrptpa llappmfifp apnngepvrp vppspqqipp lppppptppa
      481 tpppappptp qppalprtpi lvarpptpgp ghlesalapt ppstlsptaa aeqapaptpa
      541 pvtsqvpatt taelsppmpq pkirtrrnkg praargvire egtsgdgpre pnmapvtdss
      601 sggggggsng tstagasnkg tarhwppfev lnscpckcyc rhqrrhrrlp rnvsawlstp
      661 tnhlseppwv atvklagslv aglehydlqa thst
//
