LOCUS       NM_001108629             838 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus gamma-glutamyl cyclotransferase (Ggct), mRNA.
ACCESSION   NM_001108629 XM_001058292 XM_342693
VERSION     NM_001108629.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Oda,K., Makino,S., Masuda,C., Yoshiki,T., Kitamura,Y., Takata,K.,
            Yanagisawa,D., Taniguchi,T. and Tooyama,I.
  TITLE     The mRNA distribution of C7orf24, a gamma-glutamyl
            cyclotransferase, in rat tissues
  JOURNAL   J Histochem Cytochem 57 (12), 1121-1126 (2009)
   PUBMED   19687470
  REMARK    GeneRIF: the distribution pattern of the C7orf24/gamma-glutamyl
            cyclotransferase mRNA in rat tissues
REFERENCE   2  (bases 1 to 838)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 838)
  AUTHORS   Oakley,A.J., Yamada,T., Liu,D., Coggan,M., Clark,A.G. and
            Board,P.G.
  TITLE     The identification and structural characterization of C7orf24 as
            gamma-glutamyl cyclotransferase. An essential enzyme in the
            gamma-glutamyl cycle
  JOURNAL   J Biol Chem 283 (32), 22031-22042 (2008)
   PUBMED   18515354
  REMARK    Erratum:[J Biol Chem. 2008 Nov 14;283(46):32152]
REFERENCE   4  (bases 1 to 838)
  AUTHORS   Bae,E., Bingman,C.A., Aceti,D.J. and Phillips,G.N. Jr.
  TITLE     Crystal structure of Homo sapiens protein LOC79017
  JOURNAL   Proteins 70 (2), 588-591 (2008)
   PUBMED   17932939
REFERENCE   5  (bases 1 to 838)
  AUTHORS   Masuda,Y., Maeda,S., Watanabe,A., Sano,Y., Aiuchi,T., Nakajo,S.,
            Itabe,H. and Nakaya,K.
  TITLE     A novel 21-kDa cytochrome c-releasing factor is generated upon
            treatment of human leukemia U937 cells with geranylgeraniol
  JOURNAL   Biochem Biophys Res Commun 346 (2), 454-460 (2006)
   PUBMED   16765912
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1 and FM060344.1.
            
            On Feb 20, 2013 this sequence version replaced NM_001108629.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AW919608.1, BF287180.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                JAXUCZ010000004.1  85459480-85459546   c
            68-685              FM060344.1         6-623
            686-838             JAXUCZ010000004.1  85453387-85453539   c
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..838
                     /gene="Ggct"
                     /gene_synonym="Ggctl1; RGD1304876; RGD1562590"
                     /note="gamma-glutamyl cyclotransferase"
                     /db_xref="GeneID:362368"
                     /db_xref="RGD:1304876"
     exon            1..214
                     /gene="Ggct"
                     /gene_synonym="Ggctl1; RGD1304876; RGD1562590"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..640
                     /gene="Ggct"
                     /gene_synonym="Ggctl1; RGD1304876; RGD1562590"
                     /EC_number="4.3.2.9"
                     /note="gamma-glutamyl cyclotransferase-like 1"
                     /codon_start=1
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="NP_001102099.1"
                     /db_xref="GeneID:362368"
                     /db_xref="RGD:1304876"
                     /translation="MASSDCEDHAGQEGETFLYFAYGSNLLTERIHLRNPSAVFCCVA
                     RLQDFKLDFGNFQGKMSERWHGGIATIFQSPGDEVWGVVWKMNKSNLSSLDEQEGVKS
                     GVYVVIEIKVTTQQGKDITCRSYLMTNYERAPPSPQYKKVICMGAKENGLPLEYQEKL
                     NVIEPNDYKGKISDEMEDIIKKGEAKLL"
     exon            215..360
                     /gene="Ggct"
                     /gene_synonym="Ggctl1; RGD1304876; RGD1562590"
                     /inference="alignment:Splign:2.1.0"
     exon            361..496
                     /gene="Ggct"
                     /gene_synonym="Ggctl1; RGD1304876; RGD1562590"
                     /inference="alignment:Splign:2.1.0"
     exon            497..838
                     /gene="Ggct"
                     /gene_synonym="Ggctl1; RGD1304876; RGD1562590"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggggcgctg ctctttttag cagcggtatc cccgctcttc tgtgcttgaa gctgctggcg
       61 tggacaagtg gacatggcga gctccgactg tgaggaccat gcgggtcagg agggggagac
      121 gttcctgtac ttcgcctacg gcagcaatct gctgaccgag aggatccacc tgcgaaaccc
      181 ttccgccgtg ttctgctgcg tggcgcgcct gcaggacttt aagctcgact tcggcaattt
      241 ccaaggcaaa atgagtgaga ggtggcacgg aggtatagct accatttttc aaagtcctgg
      301 cgatgaagtg tggggagtag tatggaaaat gaacaaaagc aatttaagtt ctctggatga
      361 acaagaagga gttaaaagtg gagtgtatgt tgtaatagag attaaagtta caactcaaca
      421 agggaaggac atcacctgca ggagttacct gatgacgaat tatgagagag cgcccccatc
      481 accacagtat aagaaggtta tctgcatggg tgcgaaagaa aacggtttac cgctggaata
      541 tcaagagaag ttaaacgtga tagaaccaaa tgactataaa ggaaagatct cagacgagat
      601 ggaagacatc atcaagaagg gagaggcaaa actgttataa cagactctgg agatgcgcgt
      661 gctaggatga agtgcttaat gtttgcgagc aggagtctga actctgttgt ttttaacctt
      721 ttgattttca acagtgctgt gaagggcttc tcacttaggt gactctttat tttcaactgt
      781 aacagagaac tgaaatgggg gtagggatta gaaattaaaa ggggccagga gatcctga
//
