LOCUS       NM_001310058            1069 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus gamma-glutamylamine cyclotransferase (Ggact),
            transcript variant 2, mRNA.
ACCESSION   NM_001310058 XM_006252516
VERSION     NM_001310058.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Oakley,A.J., Coggan,M. and Board,P.G.
  TITLE     Identification and characterization of gamma-glutamylamine
            cyclotransferase, an enzyme responsible for
            gamma-glutamyl-epsilon-lysine catabolism
  JOURNAL   J Biol Chem 285 (13), 9642-9648 (2010)
   PUBMED   20110353
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Jun 25, 2015 this sequence version replaced XM_006252516.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.1432167.1,
                                           SRR26360176.575251.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434, SAMN16676807
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                JAXUCZ010000015.1  106399428-106399477 c
            51-107              JAXUCZ010000015.1  106384926-106384982 c
            108-1069            JAXUCZ010000015.1  106375924-106376885 c
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q25"
     gene            1..1069
                     /gene="Ggact"
                     /gene_synonym="A2ld1"
                     /note="gamma-glutamylamine cyclotransferase"
                     /db_xref="GeneID:290500"
                     /db_xref="RGD:1304748"
     exon            1..50
                     /gene="Ggact"
                     /gene_synonym="A2ld1"
                     /inference="alignment:Splign:2.1.0"
     exon            51..107
                     /gene="Ggact"
                     /gene_synonym="A2ld1"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..570
                     /gene="Ggact"
                     /gene_synonym="A2ld1"
                     /EC_number="4.3.2.8"
                     /note="AIG2-like domain-containing protein 1; AIG2-like
                     domain 1"
                     /codon_start=1
                     /product="gamma-glutamylaminecyclotransferase"
                     /protein_id="NP_001296987.1"
                     /db_xref="GeneID:290500"
                     /db_xref="RGD:1304748"
                     /translation="MCIVQNTIRKSACSQMAHIFVYGTLKRGQPNHKVMLDQSHGLAT
                     FRGRGCTVESFPLVIAGEHNIPWLLHLPGKGHCVAGEIYEVDEQMLRFLDDFEGCPSM
                     YQRTALQVRVLEWEGAGGPGDSVQCFVYSTATYAPEWLFLPYHKNYDSEGPHGLRYNP
                     RENR"
     exon            108..1069
                     /gene="Ggact"
                     /gene_synonym="A2ld1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttccgctccg cggccgggct cgctcctggt gatccccctg acccgtgcag ggacaagttg
       61 cttcctgaag gatccatgtg tattgttcaa aacacaatca gaaaaagtgc ctgcagccag
      121 atggcccaca tcttcgtgta tggcaccctg aagcggggcc agcccaacca caaagtcatg
      181 ctggaccagt cacatggctt agccaccttc cgaggccgag gctgcacagt tgagtccttc
      241 ccactggtga ttgcgggcga gcacaacata ccttggctgc tgcacctgcc aggcaagggc
      301 cattgcgtgg caggtgaaat ctatgaggtg gatgagcaga tgttgcgctt cctggatgac
      361 ttcgaaggct gccccagcat gtaccagcgt acagccctgc aggtgcgggt gctggagtgg
      421 gagggtgctg gaggccctgg ggacagtgtt cagtgcttcg tgtacagtac agccacctat
      481 gcacccgagt ggctgtttct tccctaccat aaaaactatg attctgaggg cccacacggg
      541 ctccgctaca acccccggga aaacagatga agggctagtg ccccaaatgc caacagggtg
      601 gagggaattt ggtagctgcc tggcataagc agagctctcc cagttcaact ataaaactat
      661 gtttgtcata tacgctaatc tgatgttact taattctgct tccgtcttta gtggaggagc
      721 ttgcatgtac tagatgaaaa acactctagg ctgagtcccc taaacggcag ttacagagta
      781 cctggtgctc cacactgctt tttttttttt tttttaattt gctttgctct aacctgaaca
      841 tggaatcttt tgagactaaa aggactgggc tgcagttgca tctgaacagt ttaacatatt
      901 gattcccata tatagaacct agaaagaagt ggtaagagat gctgattttg atcgaatcag
      961 tgtaaaaaca tcaagaaaag catgttgtac ctaaactatg tgctccatcc acccccacct
     1021 gcattttcta aatcacacat aaactattaa aatggccatt aaaataaaa
//
