LOCUS       NM_053398               2070 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus GDNF family receptor alpha 3 (Gfra3), mRNA.
ACCESSION   NM_053398 XM_341593
VERSION     NM_053398.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Thornton P, Hatcher JP, Robinson I, Sargent B, Franzen B, Martino
            G, Kitching L, Glover CP, Anderson D, Forsmo-Bruce H, Low CP,
            Cusdin F, Dosanjh B, Williams W, Steffen AC, Thompson S, Eklund M,
            Lloyd C, Chessell I and Hughes J.
  TITLE     Artemin-GFRalpha3 interactions partially contribute to acute
            inflammatory hypersensitivity
  JOURNAL   Neurosci Lett 545, 23-28 (2013)
   PUBMED   23603259
  REMARK    GeneRIF: These data suggest that ARTN-GFRalpha3 interactions
            partially mediate early stage nociceptive signalling following an
            inflammatory insult.
REFERENCE   2  (bases 1 to 2070)
  AUTHORS   Forrest SL and Keast JR.
  TITLE     Expression of receptors for glial cell line-derived neurotrophic
            factor family ligands in sacral spinal cord reveals separate
            targets of pelvic afferent fibers
  JOURNAL   J Comp Neurol 506 (6), 989-1002 (2008)
   PUBMED   18085594
  REMARK    GeneRIF: GFRalpha3-labeled fibers were in lamina I, the
            lateral-collateral pathway, and areas surrounding dorsal groups of
            preganglionic neurons and associated interneurons.
REFERENCE   3  (bases 1 to 2070)
  AUTHORS   Yang C, Hutto D and Sah DW.
  TITLE     Distribution of GDNF family receptor alpha3 and RET in rat and
            human non-neural tissues
  JOURNAL   J Mol Histol 37 (1-2), 69-77 (2006)
   PUBMED   16773224
  REMARK    GeneRIF: In the rat, GFRalpha3- and RET-like staining were found in
            the same non-neural cell type only in kidney.
REFERENCE   4  (bases 1 to 2070)
  AUTHORS   Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E and
            Milbrandt J.
  TITLE     Artemin is a vascular-derived neurotropic factor for developing
            sympathetic neurons
  JOURNAL   Neuron 35 (2), 267-282 (2002)
   PUBMED   12160745
REFERENCE   5  (bases 1 to 2070)
  AUTHORS   Hoke A, Cheng C and Zochodne DW.
  TITLE     Expression of glial cell line-derived neurotrophic factor family of
            growth factors in peripheral nerve injury in rats
  JOURNAL   Neuroreport 11 (8), 1651-1654 (2000)
   PUBMED   10852218
REFERENCE   6  (bases 1 to 2070)
  AUTHORS   Stover T, Gong TL, Cho Y, Altschuler RA and Lomax MI.
  TITLE     Expression of the GDNF family members and their receptors in the
            mature rat cochlea
  JOURNAL   Brain Res Mol Brain Res 76 (1), 25-35 (2000)
   PUBMED   10719212
REFERENCE   7  (bases 1 to 2070)
  AUTHORS   Nishino J, Mochida K, Ohfuji Y, Shimazaki T, Meno C, Ohishi S,
            Matsuda Y, Fujii H, Saijoh Y and Hamada H.
  TITLE     GFR alpha3, a component of the artemin receptor, is required for
            migration and survival of the superior cervical ganglion
  JOURNAL   Neuron 23 (4), 725-736 (1999)
   PUBMED   10482239
REFERENCE   8  (bases 1 to 2070)
  AUTHORS   Worby CA, Vega QC, Chao HH, Seasholtz AF, Thompson RC and Dixon JE.
  TITLE     Identification and characterization of GFRalpha-3, a novel
            Co-receptor belonging to the glial cell line-derived neurotrophic
            receptor family
  JOURNAL   J Biol Chem 273 (6), 3502-3508 (1998)
   PUBMED   9452475
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079378.1.
            
            On Apr 19, 2005 this sequence version replaced XM_341593.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079378.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132279,
                                           SAMD00132284 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..2070
                     /gene="Gfra3"
                     /note="GDNF family receptor alpha 3"
                     /db_xref="GeneID:84422"
                     /db_xref="RGD:620502"
     exon            1..138
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            139..426
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            427..519
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            520..832
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            833..936
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1071
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1160
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..2045
                     /gene="Gfra3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgcgacgc ccagcacagg cagagcgctg ccgggtccgc ggcgtccaga cccgccatgg
       61 ggctctcccg gagcccgcga ccgccgccgc tagtgatcct gctactggtg ctgtcgctgt
      121 ggctacccct tggaacagga aactcccttc ccacagagaa caggcttgtg aacagctgta
      181 cccaggccag aaaaaaatgc gaggctaatc ccgcttgcaa ggctgcctac cagcacctgg
      241 actcctgcac ccccagtctc agcagtccac tgccctcagg ggagtctgcc acatctgcag
      301 cgtgccttga agcagcacag caactcagga acagctctct catagactgc aggtgccacc
      361 ggcgcatgaa gcaccaagct acctgtctgg acatttattg gaccgttcac cctgtccgaa
      421 gccttggtga ctacgagttg gacgtctcac cctatgaaga cacagtgacc agcaaaccct
      481 ggaaaatgaa tctcagcaag ctgagcatgc tcaaaccaga ctccgacctc tgcctcaaat
      541 ttgctatgct gtgtactctt aacgacaagt gcgaccgcct ccgaaaggcc tacggggagg
      601 cgtgctcagg gatccgctgc cagcgccacc tctgcctagc tcagctgcgc tccttcttcg
      661 agaaggcggc agagtcccac gctcagggcc tgctgctgtg tccctgtgca cccgaagatg
      721 cgggctgtgg ggagcgccgg cgcaacacca tcgcccccag ttgcgccctc ccgtctgtgg
      781 cccccaactg cctagatctt cggagcttct gccgtgcgga ccctctgtgc agatcacgcc
      841 tgatggactt ccagacccac tgccacccta tggacatcct cgggacttgt gcaactgagc
      901 agtccagatg tctgcgggca tacctggggc taattgggac tgccatgacc ccaaacttca
      961 tcagcaaggt caacactact gttgccttag gctgtacctg ccgaggcagt ggcaacctgc
     1021 aggacgagtg tgaacagctg gaaaagtcct tctcccagaa cccctgcctc atggaggcca
     1081 ttgcggctaa aatgcgtttc cacagacaac tcttctccca ggactgggcg gactctactt
     1141 tttctgtgat gcagcagcag aacagcagcc ctgctctgag gccccagctc aggctacccg
     1201 ttctgtcttt cttcatcctt accttgattc tgctgcagac cctctggtaa ctgggctccc
     1261 tcagggtcct ttgtcctctc caccacaccc agaccgactt gcagcctgtg atgggagaga
     1321 aaatgctggc ctctggaaga agatgcaacc aggctcactg cacatcctgt ctgctccaga
     1381 tgaggtcttg gaagaagcga gggctgtgac cgttcagaat cctgagcggc cagctttcaa
     1441 acctctccta cttactcctg cttgggctgc tcctccctag gaccttgtac tccagtttgg
     1501 ctgtatattg tggtggtgat tagcttccca cctccagccc ttcttcctgt ttcccaggac
     1561 cacccagggc taatgactca ctcattcctg gttgccttct ccaggaaggc aggctgaggg
     1621 ttctgaggca gctgagaaag atggtccctt tgtgaggaag gctggtggtc caaccccacg
     1681 tccttctgaa tggaaggtga agacctcctg tcatgtctgc caggccatcc tgaacacttg
     1741 ggcaagaaga gctaaaagcc tttgagtctt gcttaactcc tagcactgtc tccatgtccc
     1801 ccagtccctc aggtcatgat taaacatttt gacttaagac tttggtcttt acccatttcc
     1861 ttaaatggta agtttttaca gaagtagtgg tatgttacag atacaagggg actaaccggg
     1921 tgaggaagag acccagtaac cctactgcta agtgctgtgt gacttcaggc aaatctctcg
     1981 cctctcttgt cagagctgga agaatagtaa aaataaaaga tggtgtttgt cccagttcta
     2041 agtgaaaaaa aaaaaaaaaa aaaaaaaaaa
//
