LOCUS       NM_053625               2607 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus G elongation factor, mitochondrial 1 (Gfm1),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_053625 XM_346621
VERSION     NM_053625.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   2  (bases 1 to 2607)
  AUTHORS   Tsuboi,M., Morita,H., Nozaki,Y., Akama,K., Ueda,T., Ito,K.,
            Nierhaus,K.H. and Takeuchi,N.
  TITLE     EF-G2mt is an exclusive recycling factor in mammalian mitochondrial
            protein synthesis
  JOURNAL   Mol Cell 35 (4), 502-510 (2009)
   PUBMED   19716793
REFERENCE   3  (bases 1 to 2607)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   4  (bases 1 to 2607)
  AUTHORS   Barker,C., Makris,A., Patriotis,C., Bear,S.E. and Tsichlis,P.N.
  TITLE     Identification of the gene encoding the mitochondrial elongation
            factor G in mammals
  JOURNAL   Nucleic Acids Res 21 (11), 2641-2647 (1993)
   PUBMED   8332461
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053625.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085721.1, L14684.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               JAXUCZ010000002.1  154010623-154010834
            213-365             JAXUCZ010000002.1  154012205-154012357
            366-498             JAXUCZ010000002.1  154013920-154014052
            499-703             JAXUCZ010000002.1  154016295-154016499
            704-820             JAXUCZ010000002.1  154019355-154019471
            821-971             JAXUCZ010000002.1  154020472-154020622
            972-1126            JAXUCZ010000002.1  154023793-154023947
            1127-1211           JAXUCZ010000002.1  154025027-154025111
            1212-1349           JAXUCZ010000002.1  154029793-154029930
            1350-1451           JAXUCZ010000002.1  154031401-154031502
            1452-1508           JAXUCZ010000002.1  154033682-154033738
            1509-1646           JAXUCZ010000002.1  154036228-154036365
            1647-1729           JAXUCZ010000002.1  154037496-154037578
            1730-1892           JAXUCZ010000002.1  154047396-154047558
            1893-2037           JAXUCZ010000002.1  154049148-154049292
            2038-2198           JAXUCZ010000002.1  154053867-154054027
            2199-2252           JAXUCZ010000002.1  154054964-154055017
            2253-2607           JAXUCZ010000002.1  154055169-154055523
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q32"
     gene            1..2607
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /note="G elongation factor, mitochondrial 1"
                     /db_xref="GeneID:114017"
                     /db_xref="RGD:631396"
     exon            1..212
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..2384
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /note="mitochondrial elongation factor G; elongation
                     factor G1; EF-Gmt; mEF-G 1; elongation factor G 1,
                     mitochondrial"
                     /codon_start=1
                     /product="elongation factor G, mitochondrial"
                     /protein_id="NP_446077.2"
                     /db_xref="GeneID:114017"
                     /db_xref="RGD:631396"
                     /translation="MRLLRITAGLGRGPLPRVPAILGWQGKQANWKTYRWCSSGSIPN
                     EKIRNIGISAHIDSGKTTLTERVLYYTGRIATMHEVKGKDGVGAVMDSMELERQRGIT
                     IQSAATYTMWRDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVS
                     RQMKRYNVPFLTFINKLDRMGSNPARALQQMRSKLNHNAAFVQIPIGLEGDFKGIIDL
                     IEERAIYFDGDFGQIVRYDEIPADLRAAAADHRQELIECVANSDEQLGELFLEEKIPS
                     VSDLKLAIRRATLSRSFTPVFLGSALKNKGVQPLLDAVLEFLPNPSEVQNYALLNQND
                     SKEKNKILMNPKRDDSHPFVGLAFKLEAGRFGQLTYVRNYQGELKKGSTIYNTRTGKK
                     VRVQRLVRMHADMMEDVEEVYAGDICALFGIDCASGDTFTNKDNSDLSMESIHVPDPV
                     ISVAMKPSNKNDLEKFSKGIARFTREDPTFKVHFDTESKETIVSGMGELHLEIYAQRM
                     EREYGCPCITGKPKVAFRETVTAPVPFDFTHKKQSGGAGQYGKVIGVLEPLAPEDYTK
                     LEFSDETFGANVPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEI
                     SFIRAGEGALKQALASATLCIIEPIMSVEVIAPNEFQGAVFAGINRRHGVITGQDGIE
                     DYFTLYADVPLNNMFGYSTELRSCTEGKGEYTMEYNRYQPCSPSTQEELVNKYLEATG
                     QLPVKKGKAKN"
     exon            213..365
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            366..498
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            499..703
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            704..820
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            821..971
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1126
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1211
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1349
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1451
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1508
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1646
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1729
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1892
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..2037
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2198
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2252
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2607
                     /gene="Gfm1"
                     /gene_synonym="EF-G; Efg; Gfm"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcccggaag tgctcctgtg gctggagttg caggcgtgac tttgagcgct tcccgctctg
       61 ctgccggcgc tgagcacaac agagcacagc ggagcaggaa ccctggaagt ggctgttcca
      121 gacttgtcat gcggctgctg cggatcactg caggcctggg gcgtgggccg ctccctcggg
      181 tccctgccat cctgggttgg caggggaagc aggctaattg gaagacctac cgatggtgtt
      241 cgtcaggatc aattcccaat gagaaaatcc ggaacattgg aatctcggct cacattgatt
      301 ctgggaagac gacgttaaca gaacgggtgc tgtactacac cggcaggatt gccacgatgc
      361 acgaggtgaa aggtaaagat ggagtcggtg ctgtcatgga ctccatggag ctagagagac
      421 agcgagggat cactattcag tcagcagcta cctacaccat gtggagagat gtcaatatca
      481 acatcataga cactccaggc cacgtggact tcacaataga agtggaaagg gccctgcgag
      541 tcctggatgg tgcggtcctt gtcctctgtg cagtcggtgg agtgcagtgc cagaccatga
      601 ctgtcagtcg ccagatgaag cgctacaacg ttcccttttt aaccttcatt aacaaactgg
      661 accgaatggg ctccaaccca gccagggccc ttcagcaaat gagatccaaa ctaaatcaca
      721 atgctgcatt tgtgcaaata cccattggtt tagaggggga ttttaaggga attatagacc
      781 tcattgaaga acgagccatt tactttgatg gagactttgg tcagattgtt cgatatgatg
      841 agattccggc tgatctgagg gccgcagcag ctgaccaccg gcaggagctg attgaatgtg
      901 tggctaattc agatgagcag cttggtgagc tgtttctgga agaaaaaatc ccctcagtgt
      961 ctgatttaaa gttagcgatc cggagagcta ctctgagtag atcctttact cctgtgttct
     1021 tgggaagtgc tctgaagaac aaaggagttc agcctctcct ggatgctgtc ttagaattcc
     1081 tccccaatcc atctgaagtc cagaattacg ctctactcaa tcagaatgac tcaaaagaga
     1141 agaacaaaat cctaatgaac cccaaaagag acgactcgca cccgtttgta ggcctggctt
     1201 ttaaattgga ggcaggccgt ttcggacagt taacttacgt ccgcaattat caaggcgaac
     1261 tgaagaaggg aagcaccatc tacaacacga ggacaggaaa gaaagtgcgc gtgcagcggc
     1321 tggtgcgcat gcatgccgac atgatggagg atgttgaaga agtatatgcc ggagacatct
     1381 gtgcgttgtt tggcattgac tgtgcaagtg gagacacatt cacaaacaaa gacaacagtg
     1441 acctttctat ggaatcgatt catgttcctg atcctgtcat ttcagtagca atgaagcctt
     1501 ctaacaagaa tgatctggaa aaattttcca aaggtattgc caggtttaca cgggaagacc
     1561 caacatttaa agtccacttt gacacagaga gcaaggagac gattgtgtct ggaatgggag
     1621 aattgcacct ggagatctat gctcagagaa tggagagaga atatggctgt ccttgtatca
     1681 caggaaagcc caaagtggcg tttagagaaa ccgttactgc ccctgtgcca tttgatttta
     1741 cacataaaaa gcagtcgggt ggtgccggcc agtatggaaa agtgataggg gtgctggagc
     1801 ccttggcccc ggaggactac acgaagttgg agttttccga tgagaccttt ggggccaatg
     1861 ttccaaagca gtttgttccc gccgttgaga aggggttttt ggatgcctgc gaaaaagggc
     1921 ctctttctgg tcacaagctt tctgggctcc ggtttgttct gcaagatgga gcacaccaca
     1981 tggtggattc taacgagatc tctttcatcc gagctggaga aggtgctctt aaacaagcct
     2041 tggccagtgc cacattgtgt attattgaac ctatcatgtc cgtggaagtc atcgccccaa
     2101 atgagtttca gggagcagtg tttgcaggaa ttaaccggcg ccatggagtg attacagggc
     2161 aagatggaat tgaggactat ttcacgctct acgctgatgt tcccctaaat aatatgtttg
     2221 gttattccac tgagcttagg tcttgcacag agggaaaagg agagtacaca atggagtaca
     2281 acagatacca accatgttcc ccatccacac aagaagagct tgtcaataag tatttggaag
     2341 ctacaggtca acttcccgta aaaaaaggaa aagccaagaa ctgactctca gtggtacttt
     2401 gaacgtactg acagtttgac tacaagacgt aaggatgatg gatgccggta gaatgaattc
     2461 agacggctga aacagattta ggagcccctg ccatctcgtg ttcaggagct tctatatacg
     2521 tgcaagataa ctagataact atgtgtattt aaactgtatt tctattattt agtaaaagat
     2581 cttaaataaa attatattat tactaaa
//
